Motif ID: Nr4a2

Z-value: 0.588


Transcription factors associated with Nr4a2:

Gene SymbolEntrez IDGene Name
Nr4a2 ENSMUSG00000026826.7 Nr4a2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr4a2mm10_v2_chr2_-_57124003_571240710.292.4e-01Click!


Activity profile for motif Nr4a2.

activity profile for motif Nr4a2


Sorted Z-values histogram for motif Nr4a2

Sorted Z-values for motif Nr4a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr4a2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_26229707 2.325 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr18_+_86711059 1.595 ENSMUST00000068423.3
 Cbln2
cerebellin 2 precursor protein
chr7_-_100514800 1.377 ENSMUST00000054923.7
 Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr11_+_70657687 1.115 ENSMUST00000134087.1
ENSMUST00000170716.1
 Eno3

enolase 3, beta muscle

chr8_+_68880491 1.108 ENSMUST00000015712.8
 Lpl
lipoprotein lipase
chr2_+_4976113 0.952 ENSMUST00000167607.1
ENSMUST00000115010.2
 Ucma

upper zone of growth plate and cartilage matrix associated

chr11_+_70657196 0.946 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
 Eno3



enolase 3, beta muscle



chr9_-_32344237 0.934 ENSMUST00000034533.5
 Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr6_-_124814288 0.819 ENSMUST00000172132.2
 Tpi1
triosephosphate isomerase 1
chrX_+_150589907 0.791 ENSMUST00000080884.4
 Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr15_-_42676967 0.757 ENSMUST00000022921.5
 Angpt1
angiopoietin 1
chr2_-_129699833 0.717 ENSMUST00000028883.5
 Pdyn
prodynorphin
chr10_+_93589413 0.709 ENSMUST00000181835.1
 4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr13_+_93304066 0.690 ENSMUST00000109493.1
 Homer1
homer homolog 1 (Drosophila)
chrX_-_48513518 0.672 ENSMUST00000114945.2
ENSMUST00000037349.7
 Aifm1

apoptosis-inducing factor, mitochondrion-associated 1

chr5_+_111581422 0.637 ENSMUST00000064930.3
 C130026L21Rik
RIKEN cDNA C130026L21 gene
chr5_-_121527186 0.604 ENSMUST00000152270.1
 Mapkapk5
MAP kinase-activated protein kinase 5
chrX_-_73921917 0.575 ENSMUST00000114389.3
 Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr2_-_73911323 0.572 ENSMUST00000111996.1
ENSMUST00000018914.2
 Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chrX_-_73921930 0.528 ENSMUST00000033763.8
 Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chrX_-_73921828 0.510 ENSMUST00000096316.3
ENSMUST00000114390.1
ENSMUST00000114391.3
ENSMUST00000114387.1
 Naa10



N(alpha)-acetyltransferase 10, NatA catalytic subunit



chr5_-_137613759 0.503 ENSMUST00000155251.1
ENSMUST00000124693.1
 Pcolce

procollagen C-endopeptidase enhancer protein

chr1_+_137966529 0.483 ENSMUST00000182158.1
 A430106G13Rik
RIKEN cDNA A430106G13 gene
chr10_-_40302186 0.478 ENSMUST00000099945.4
 Amd1
S-adenosylmethionine decarboxylase 1
chr17_+_47737030 0.465 ENSMUST00000086932.3
 Tfeb
transcription factor EB
chr18_+_36664060 0.415 ENSMUST00000036765.7
 Eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
chr15_-_89425856 0.384 ENSMUST00000109313.2
 Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr2_+_61593077 0.374 ENSMUST00000112495.1
ENSMUST00000112501.2
 Tank

TRAF family member-associated Nf-kappa B activator

chr10_+_110920170 0.372 ENSMUST00000020403.5
 Csrp2
cysteine and glycine-rich protein 2
chr4_-_36136463 0.365 ENSMUST00000098151.2
 Lingo2
leucine rich repeat and Ig domain containing 2
chr10_-_93589621 0.362 ENSMUST00000020203.6
 Snrpf
small nuclear ribonucleoprotein polypeptide F
chr7_+_4119525 0.349 ENSMUST00000119661.1
ENSMUST00000129423.1
 Ttyh1

tweety homolog 1 (Drosophila)

chr7_+_4119556 0.346 ENSMUST00000079415.5
 Ttyh1
tweety homolog 1 (Drosophila)
chr10_-_117224480 0.340 ENSMUST00000020382.6
 Yeats4
YEATS domain containing 4
chr2_+_105668888 0.338 ENSMUST00000111086.4
ENSMUST00000111087.3
 Pax6

paired box gene 6

chr17_+_29360923 0.337 ENSMUST00000024810.6
 Fgd2
FYVE, RhoGEF and PH domain containing 2
chr8_-_119840522 0.337 ENSMUST00000168698.1
ENSMUST00000034285.6
 Cotl1

coactosin-like 1 (Dictyostelium)

chr18_-_15063560 0.335 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr9_-_22002599 0.335 ENSMUST00000115336.2
ENSMUST00000044926.5
 Ccdc151

coiled-coil domain containing 151

chr2_+_79707780 0.334 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
 Ppp1r1c


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chr10_+_42502197 0.329 ENSMUST00000105499.1
 Snx3
sorting nexin 3
chrX_+_7579666 0.325 ENSMUST00000115740.1
ENSMUST00000115739.1
 Foxp3

forkhead box P3

chr3_+_14578609 0.323 ENSMUST00000029069.6
ENSMUST00000165922.2
 E2f5

E2F transcription factor 5

chr2_-_101621033 0.321 ENSMUST00000090513.4
 B230118H07Rik
RIKEN cDNA B230118H07 gene
chr11_-_52282564 0.318 ENSMUST00000086844.3
 Tcf7
transcription factor 7, T cell specific
chr3_-_95133989 0.306 ENSMUST00000172572.2
ENSMUST00000173462.2
 Scnm1

sodium channel modifier 1

chr8_-_13494479 0.303 ENSMUST00000033828.5
 Gas6
growth arrest specific 6
chr8_-_46211284 0.298 ENSMUST00000034049.4
 Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chrX_-_142390334 0.295 ENSMUST00000112907.1
 Acsl4
acyl-CoA synthetase long-chain family member 4
chr9_-_106656081 0.293 ENSMUST00000023959.7
 Grm2
glutamate receptor, metabotropic 2
chr9_+_95637601 0.282 ENSMUST00000015498.8
 Pcolce2
procollagen C-endopeptidase enhancer 2
chr10_-_35711891 0.279 ENSMUST00000080898.2
 Amd2
S-adenosylmethionine decarboxylase 2
chr4_-_150914401 0.274 ENSMUST00000105675.1
 Park7
Parkinson disease (autosomal recessive, early onset) 7
chr18_-_56975333 0.271 ENSMUST00000139243.2
ENSMUST00000025488.8
 C330018D20Rik

RIKEN cDNA C330018D20 gene

chr9_+_108392820 0.266 ENSMUST00000035234.4
 1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr8_+_70863127 0.247 ENSMUST00000050921.2
 A230052G05Rik
RIKEN cDNA A230052G05 gene
chr1_+_63176818 0.242 ENSMUST00000129339.1
 Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr5_-_31202215 0.242 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
 Zfp513


zinc finger protein 513


chr2_+_75832168 0.241 ENSMUST00000047232.7
ENSMUST00000111952.2
 Agps

alkylglycerone phosphate synthase

chr14_-_78088994 0.232 ENSMUST00000118785.2
ENSMUST00000066437.4
 Fam216b

family with sequence similarity 216, member B

chr13_-_97747373 0.220 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_-_141623799 0.208 ENSMUST00000038661.7
 Slc25a34
solute carrier family 25, member 34
chr1_+_131910458 0.205 ENSMUST00000062264.6
 Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr3_+_84925476 0.204 ENSMUST00000107675.1
 Fbxw7
F-box and WD-40 domain protein 7
chr2_-_155945282 0.201 ENSMUST00000040162.2
 Gdf5
growth differentiation factor 5
chr11_-_100822525 0.175 ENSMUST00000107358.2
 Stat5b
signal transducer and activator of transcription 5B
chr11_-_70656467 0.166 ENSMUST00000131642.1
 Gm12319
predicted gene 12319
chr10_+_90829835 0.147 ENSMUST00000179964.1
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_+_90829780 0.145 ENSMUST00000179337.2
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_+_167618246 0.144 ENSMUST00000111380.1
 Rxrg
retinoid X receptor gamma
chr7_+_125603420 0.143 ENSMUST00000033000.6
 Il21r
interleukin 21 receptor
chr13_+_94875600 0.142 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr4_+_99955715 0.132 ENSMUST00000102783.4
 Pgm2
phosphoglucomutase 2
chr3_+_4211716 0.130 ENSMUST00000170943.1
 Gm8775
predicted gene 8775
chr1_-_124045247 0.128 ENSMUST00000112603.2
 Dpp10
dipeptidylpeptidase 10
chr10_-_99759658 0.125 ENSMUST00000056085.4
 Csl
citrate synthase like
chr11_-_109722214 0.122 ENSMUST00000020938.7
 Fam20a
family with sequence similarity 20, member A
chr2_+_61593125 0.118 ENSMUST00000112494.1
 Tank
TRAF family member-associated Nf-kappa B activator
chr10_-_20725023 0.108 ENSMUST00000020165.7
 Pde7b
phosphodiesterase 7B
chr10_+_53337686 0.106 ENSMUST00000046221.6
ENSMUST00000163319.1
 Pln

phospholamban

chr7_+_4690760 0.106 ENSMUST00000048248.7
 Brsk1
BR serine/threonine kinase 1
chr16_+_44139821 0.094 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
 Naa50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr8_+_117095854 0.090 ENSMUST00000034308.8
ENSMUST00000167370.1
ENSMUST00000176860.1
 Bcmo1


beta-carotene 15,15'-monooxygenase


chr1_-_167393826 0.087 ENSMUST00000028005.2
 Mgst3
microsomal glutathione S-transferase 3
chr4_+_136357423 0.074 ENSMUST00000182167.1
 Gm17388
predicted gene, 17388
chr17_-_43667015 0.063 ENSMUST00000024705.4
 Slc25a27
solute carrier family 25, member 27
chr19_-_6921753 0.062 ENSMUST00000173635.1
 Esrra
estrogen related receptor, alpha
chr8_-_64733534 0.048 ENSMUST00000141021.1
 Sc4mol
sterol-C4-methyl oxidase-like
chr1_+_57845534 0.048 ENSMUST00000169772.1
 Spats2l
spermatogenesis associated, serine-rich 2-like
chr2_-_26237368 0.035 ENSMUST00000036187.8
 Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr17_-_25785324 0.035 ENSMUST00000150324.1
 Haghl
hydroxyacylglutathione hydrolase-like
chr2_+_121295437 0.033 ENSMUST00000110639.1
 Map1a
microtubule-associated protein 1 A
chr14_-_30915387 0.022 ENSMUST00000166622.1
 Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr2_+_59160838 0.014 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
 Pkp4


plakophilin 4


chr2_-_73892619 0.011 ENSMUST00000112007.1
ENSMUST00000112016.2
 Atf2

activating transcription factor 2

chr17_-_25785533 0.011 ENSMUST00000140738.1
ENSMUST00000145053.1
ENSMUST00000138759.1
ENSMUST00000133071.1
ENSMUST00000077938.3
 Haghl




hydroxyacylglutathione hydrolase-like




chr9_+_118506226 0.008 ENSMUST00000084820.4
 Golga4
golgi autoantigen, golgin subfamily a, 4
chr9_-_64737623 0.007 ENSMUST00000169058.1
 Rab11a
RAB11a, member RAS oncogene family
chr7_+_120635176 0.002 ENSMUST00000033176.5
 Uqcrc2
ubiquinol cytochrome c reductase core protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.3 1.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 0.8 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 0.8 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 0.8 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.2 0.9 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 0.3 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.2 0.5 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 0.6 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.3 GO:0003104 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 0.6 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 0.2 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.0 0.2 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.2 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.3 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 1.7 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.3 GO:0032306 regulation of prostaglandin secretion(GO:0032306) embryonic process involved in female pregnancy(GO:0060136)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 2.1 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 2.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0051562 cellular triglyceride homeostasis(GO:0035356) negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 0.7 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 2.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 1.7 GO:0031415 NatA complex(GO:0031415)
0.2 1.1 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.1 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 1.7 GO:0005930 axoneme(GO:0005930)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2 2.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 0.8 GO:0019808 polyamine binding(GO:0019808)
0.2 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.8 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.3 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.8 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.9 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 ST_ADRENERGIC Adrenergic Pathway
0.0 0.6 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.3 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.1 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.7 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.8 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs