ISMARA results: Nr4a3

Motif ID: Nr4a3

Z-value: 0.570

Transcription factors associated with Nr4a3:

Gene Symbol	Entrez ID	Gene Name
Nr4a3	ENSMUSG00000028341.3	Nr4a3

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Nr4a3	mm10_v2_chr4_+_48045144_48045160	0.32	1.9e-01	Click!

View svg image
View png image

Top targets:

Search:

Show entries

Showing 1 to 20 of 83 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_66968559	1.345	ENSMUST00000127184.1	Limch1	LIM and calponin homology domains 1
chr19_-_4334001	1.249	ENSMUST00000176653.1	Kdm2a	lysine (K)-specific demethylase 2A
chr15_+_25773985	1.093	ENSMUST00000125667.1	Myo10	myosin X
chr16_+_10545390	1.046	ENSMUST00000115827.1 ENSMUST00000038145.6 ENSMUST00000150894.1	Clec16a	C-type lectin domain family 16, member A
chrY_-_1245685	0.997	ENSMUST00000143286.1 ENSMUST00000137048.1 ENSMUST00000069309.7 ENSMUST00000139365.1	Uty	ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr8_+_124793013	0.858	ENSMUST00000167588.1	Trim67	tripartite motif-containing 67
chr8_+_124793061	0.779	ENSMUST00000041106.7	Trim67	tripartite motif-containing 67
chr5_+_66968416	0.721	ENSMUST00000038188.7	Limch1	LIM and calponin homology domains 1
chr9_-_54661666	0.685	ENSMUST00000128624.1	Acsbg1	acyl-CoA synthetase bubblegum family member 1
chr4_+_43578921	0.682	ENSMUST00000030190.8	Rgp1	RGP1 retrograde golgi transport homolog (S. cerevisiae)
chrY_-_1245753	0.669	ENSMUST00000154004.1	Uty	ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr11_-_115267236	0.626	ENSMUST00000106554.1	Grin2c	glutamate receptor, ionotropic, NMDA2C (epsilon 3)
chr11_-_55033398	0.590	ENSMUST00000108883.3 ENSMUST00000102727.2	Anxa6	annexin A6
chr15_+_100761741	0.582	ENSMUST00000023776.6	Slc4a8	solute carrier family 4 (anion exchanger), member 8
chrX_+_73675500	0.538	ENSMUST00000171398.1	Slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr7_+_102267795	0.519	ENSMUST00000033289.4	Stim1	stromal interaction molecule 1
chr17_-_35909626	0.475	ENSMUST00000141132.1	Atat1	alpha tubulin acetyltransferase 1
chr7_-_98162318	0.472	ENSMUST00000107112.1	Capn5	calpain 5
chr5_+_16553488	0.465	ENSMUST00000030683.3	Hgf	hepatocyte growth factor
chr19_+_46152505	0.439	ENSMUST00000026254.7	Gbf1	golgi-specific brefeldin A-resistance factor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Showing 1 to 20 of 31 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.2	1.5	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.3	1.4	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.2	1.2	GO:0033184	positive regulation of histone ubiquitination(GO:0033184)
0.0	1.1	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.7	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.2	0.6	GO:0071929	alpha-tubulin acetylation(GO:0071929)
0.0	0.6	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	0.6	GO:0001964	startle response(GO:0001964)
0.1	0.5	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.1	0.5	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.0	0.5	GO:0072337	modified amino acid transport(GO:0072337)
0.1	0.4	GO:0070973	COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.4	GO:2000331	regulation of terminal button organization(GO:2000331)
0.1	0.4	GO:0002182	cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0	0.4	GO:0030432	peristalsis(GO:0030432)
0.0	0.4	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.4	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.4	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.4	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)

Gene overrepresentation in cellular_component category:

Search:

Show entries

Showing 1 to 14 of 14 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.1	GO:0016459	myosin complex(GO:0016459)
0.0	0.7	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.6	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.6	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.6	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	0.6	GO:0031902	late endosome membrane(GO:0031902)
0.1	0.5	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.4	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.4	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	0.3	GO:0042642	actomyosin, myosin complex part(GO:0042642)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.3	GO:0042575	DNA polymerase complex(GO:0042575)

Gene overrepresentation in molecular_function category:

Search:

Show entries

Showing 1 to 20 of 28 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.5	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2	1.2	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	1.1	GO:0030507	spectrin binding(GO:0030507)
0.1	0.7	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	0.6	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.6	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.6	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.5	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.5	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.5	GO:0042056	chemoattractant activity(GO:0042056)
0.1	0.4	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.4	GO:0008556	sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0	0.4	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.4	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.4	GO:0046966	thyroid hormone receptor binding(GO:0046966)

Gene overrepresentation in C2:CP category:

Search:

Show entries

Showing 1 to 3 of 3 entries

Total log-likelihood	Term	Description
1.1	PID_NETRIN_PATHWAY	Netrin-mediated signaling events
0.5	PID_UPA_UPAR_PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4	PID_ARF_3PATHWAY	Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Showing 1 to 9 of 9 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.1	REACTOME_NETRIN1_SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.6	REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	0.5	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.4	REACTOME_COPI_MEDIATED_TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.4	REACTOME_SIGNALING_BY_ROBO_RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME_IL_7_SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.3	REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME_ACTIVATION_OF_RAC	Genes involved in Activation of Rac