Motif ID: Obox3

Z-value: 0.527


Transcription factors associated with Obox3:

Gene SymbolEntrez IDGene Name
Obox3 ENSMUSG00000066772.6 Obox3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Obox3mm10_v2_chr7_-_15627876_156278760.145.9e-01Click!


Activity profile for motif Obox3.

activity profile for motif Obox3


Sorted Z-values histogram for motif Obox3

Sorted Z-values for motif Obox3



Network of associatons between targets according to the STRING database.



First level regulatory network of Obox3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_43393346 1.619 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr6_+_4902913 1.422 ENSMUST00000175889.1
ENSMUST00000168998.2
 Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr11_+_70459940 1.228 ENSMUST00000147289.1
ENSMUST00000126105.1
 Zmynd15

zinc finger, MYND-type containing 15

chr6_-_91807318 1.172 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr12_+_81631369 1.140 ENSMUST00000036116.5
 Ttc9
tetratricopeptide repeat domain 9
chr14_+_61138445 1.072 ENSMUST00000089394.3
ENSMUST00000119509.1
 Sacs

sacsin

chr6_-_91807424 1.028 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chr1_-_119836999 0.992 ENSMUST00000163621.1
ENSMUST00000168303.1
 Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chr1_+_178187721 0.790 ENSMUST00000159284.1
 Desi2
desumoylating isopeptidase 2
chr4_+_74013442 0.785 ENSMUST00000098006.2
ENSMUST00000084474.5
 Frmd3

FERM domain containing 3

chr1_+_118389058 0.732 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
 Clasp1



CLIP associating protein 1



chr6_-_122340200 0.716 ENSMUST00000159384.1
 Phc1
polyhomeotic-like 1 (Drosophila)
chr19_+_3768112 0.688 ENSMUST00000005518.9
ENSMUST00000113967.1
ENSMUST00000152935.1
ENSMUST00000176262.1
ENSMUST00000176407.1
ENSMUST00000176926.1
ENSMUST00000176512.1
 Suv420h1






suppressor of variegation 4-20 homolog 1 (Drosophila)






chr14_-_19977249 0.641 ENSMUST00000160013.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr18_+_37496997 0.640 ENSMUST00000059571.5
 Pcdhb19
protocadherin beta 19
chr19_+_44992127 0.639 ENSMUST00000179305.1
 Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_-_52232296 0.608 ENSMUST00000114512.1
 Gls
glutaminase
chr2_+_136892168 0.579 ENSMUST00000099311.2
 Slx4ip
SLX4 interacting protein
chr11_-_70459957 0.534 ENSMUST00000019064.2
 Cxcl16
chemokine (C-X-C motif) ligand 16
chr4_+_74242468 0.462 ENSMUST00000077851.3
 Kdm4c
lysine (K)-specific demethylase 4C
chr10_-_127341583 0.453 ENSMUST00000026474.3
 Gli1
GLI-Kruppel family member GLI1
chr9_-_50617228 0.444 ENSMUST00000147671.1
ENSMUST00000145139.1
ENSMUST00000155435.1
 AU019823


expressed sequence AU019823


chr4_+_115000174 0.386 ENSMUST00000129957.1
 Stil
Scl/Tal1 interrupting locus
chr7_+_35802593 0.381 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr14_-_19977040 0.376 ENSMUST00000159028.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr19_+_3767397 0.362 ENSMUST00000113974.4
ENSMUST00000113972.2
ENSMUST00000113973.1
ENSMUST00000113977.2
ENSMUST00000052699.6
ENSMUST00000113968.2
 Suv420h1





suppressor of variegation 4-20 homolog 1 (Drosophila)





chr1_+_178187417 0.358 ENSMUST00000161075.1
ENSMUST00000027783.7
 Desi2

desumoylating isopeptidase 2

chr14_-_19977151 0.355 ENSMUST00000055100.7
ENSMUST00000162425.1
 Gng2

guanine nucleotide binding protein (G protein), gamma 2

chrX_+_142227923 0.346 ENSMUST00000042329.5
 Nxt2
nuclear transport factor 2-like export factor 2
chr19_+_3767953 0.318 ENSMUST00000113970.1
 Suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr18_-_60848911 0.309 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
 Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chr13_-_23369156 0.306 ENSMUST00000125328.1
ENSMUST00000145451.1
ENSMUST00000050101.2
 Zfp322a


zinc finger protein 322A


chrX_+_134295225 0.289 ENSMUST00000037687.7
 Tmem35
transmembrane protein 35
chr4_+_62663620 0.286 ENSMUST00000126338.1
 Rgs3
regulator of G-protein signaling 3
chr7_-_25398697 0.229 ENSMUST00000105177.2
ENSMUST00000149349.1
 Lipe

lipase, hormone sensitive

chr9_+_108460518 0.198 ENSMUST00000061209.5
 Ccdc71
coiled-coil domain containing 71
chrX_+_74424632 0.181 ENSMUST00000114129.2
ENSMUST00000132749.1
 Ikbkg

inhibitor of kappaB kinase gamma

chr9_+_109051090 0.155 ENSMUST00000059097.8
 Shisa5
shisa homolog 5 (Xenopus laevis)
chr1_-_133701881 0.154 ENSMUST00000167348.1
 Gm17678
predicted gene, 17678
chr18_+_42511496 0.149 ENSMUST00000025375.7
 Tcerg1
transcription elongation regulator 1 (CA150)
chrX_+_74424534 0.148 ENSMUST00000135165.1
ENSMUST00000114128.1
ENSMUST00000114133.2
ENSMUST00000004330.3
 Ikbkg



inhibitor of kappaB kinase gamma



chr10_+_111972664 0.125 ENSMUST00000163048.1
ENSMUST00000174653.1
 Krr1

KRR1, small subunit (SSU) processome component, homolog (yeast)

chr14_-_69805524 0.111 ENSMUST00000022665.2
 Rhobtb2
Rho-related BTB domain containing 2
chr2_-_24049389 0.099 ENSMUST00000051416.5
 Hnmt
histamine N-methyltransferase
chr2_+_69722797 0.057 ENSMUST00000090858.3
 Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr2_+_152962485 0.050 ENSMUST00000099197.2
ENSMUST00000103155.3
 Ttll9

tubulin tyrosine ligase-like family, member 9

chr11_+_109649376 0.045 ENSMUST00000106677.1
 Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr7_-_103843154 0.043 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr4_+_115000156 0.026 ENSMUST00000030490.6
 Stil
Scl/Tal1 interrupting locus
chr17_+_25786566 0.014 ENSMUST00000095500.4
 Ccdc78
coiled-coil domain containing 78
chr1_+_140246216 0.009 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
 Kcnt2



potassium channel, subfamily T, member 2



chr1_-_155232710 0.008 ENSMUST00000035914.3
 BC034090
cDNA sequence BC034090
chr3_+_55116174 0.006 ENSMUST00000146109.1
 Spg20
spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)
chrX_+_52791179 0.000 ENSMUST00000101588.1
 Ccdc160
coiled-coil domain containing 160

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 2.2 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.1 0.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.5 GO:0060032 notochord regression(GO:0060032)
0.1 0.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 1.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:0033504 floor plate development(GO:0033504)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.5 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.6 GO:0050919 negative chemotaxis(GO:0050919)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 0.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.0 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 1.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 2.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.0 GO:0030492 hemoglobin binding(GO:0030492) hemoglobin alpha binding(GO:0031721)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.4 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.4 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor