Motif ID: Obox6_Obox5
Z-value: 0.713
Transcription factors associated with Obox6_Obox5:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Obox5 | ENSMUSG00000074366.3 | Obox5 |
Obox6 | ENSMUSG00000041583.7 | Obox6 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.0 | GO:0014016 | neuroblast differentiation(GO:0014016) |
0.4 | 1.7 | GO:0015825 | L-serine transport(GO:0015825) |
0.4 | 1.5 | GO:0060155 | platelet dense granule organization(GO:0060155) |
0.3 | 1.7 | GO:0015671 | oxygen transport(GO:0015671) |
0.3 | 1.7 | GO:0061642 | chemoattraction of axon(GO:0061642) |
0.3 | 0.9 | GO:0031204 | posttranslational protein targeting to membrane, translocation(GO:0031204) |
0.3 | 0.9 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
0.3 | 0.9 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
0.3 | 1.5 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
0.3 | 1.6 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.2 | 0.7 | GO:0019405 | alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
0.2 | 2.0 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.2 | 0.6 | GO:0002014 | vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014) |
0.2 | 0.6 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
0.2 | 0.5 | GO:0045004 | DNA replication proofreading(GO:0045004) |
0.1 | 0.6 | GO:0033087 | negative regulation of immature T cell proliferation(GO:0033087) |
0.1 | 0.4 | GO:0070543 | response to linoleic acid(GO:0070543) |
0.1 | 0.9 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
0.1 | 0.4 | GO:0035604 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529) |
0.1 | 0.6 | GO:0048682 | axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682) |
0.1 | 0.3 | GO:1990523 | bone regeneration(GO:1990523) |
0.1 | 0.6 | GO:0061101 | neuroendocrine cell differentiation(GO:0061101) |
0.1 | 0.8 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.1 | 0.9 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.1 | 0.5 | GO:0033762 | response to glucagon(GO:0033762) |
0.1 | 0.6 | GO:0048254 | snoRNA localization(GO:0048254) |
0.1 | 0.5 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
0.1 | 0.4 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
0.1 | 1.7 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.1 | 0.3 | GO:1903048 | regulation of acetylcholine-gated cation channel activity(GO:1903048) |
0.1 | 0.3 | GO:0048289 | isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293) |
0.1 | 0.4 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.1 | 0.5 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
0.1 | 0.6 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
0.1 | 0.4 | GO:0032346 | positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) |
0.1 | 0.3 | GO:0010796 | regulation of multivesicular body size(GO:0010796) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
0.1 | 0.3 | GO:1904430 | negative regulation of t-circle formation(GO:1904430) |
0.1 | 0.5 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
0.1 | 0.2 | GO:1903225 | regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225) |
0.1 | 0.4 | GO:0003383 | apical constriction(GO:0003383) |
0.1 | 0.2 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.1 | 0.1 | GO:1903899 | positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
0.1 | 0.1 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
0.1 | 0.6 | GO:0048664 | neuron fate determination(GO:0048664) |
0.1 | 0.4 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.1 | 0.3 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.1 | 0.3 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.1 | 0.3 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
0.1 | 0.6 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.1 | 0.3 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.1 | 0.2 | GO:0036233 | glycine import(GO:0036233) |
0.1 | 0.3 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
0.0 | 0.2 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.0 | 0.2 | GO:0019659 | fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
0.0 | 0.3 | GO:0086028 | bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) |
0.0 | 0.2 | GO:0015889 | cobalamin transport(GO:0015889) |
0.0 | 0.4 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
0.0 | 0.5 | GO:1903894 | regulation of IRE1-mediated unfolded protein response(GO:1903894) |
0.0 | 0.2 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
0.0 | 0.3 | GO:0021539 | subthalamus development(GO:0021539) |
0.0 | 0.2 | GO:0001306 | age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571) |
0.0 | 0.3 | GO:0098535 | de novo centriole assembly(GO:0098535) |
0.0 | 0.3 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.0 | 0.2 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
0.0 | 0.1 | GO:0015747 | urate transport(GO:0015747) |
0.0 | 0.3 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.0 | 0.2 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.0 | 0.2 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
0.0 | 0.4 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.0 | 0.1 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
0.0 | 0.6 | GO:0051451 | myoblast migration(GO:0051451) |
0.0 | 0.1 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.0 | 0.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.0 | 1.7 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 0.2 | GO:0031424 | keratinization(GO:0031424) |
0.0 | 0.4 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
0.0 | 0.2 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.0 | 0.3 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) protein K6-linked ubiquitination(GO:0085020) |
0.0 | 0.1 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
0.0 | 0.3 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.0 | 0.2 | GO:1904426 | positive regulation of GTP binding(GO:1904426) |
0.0 | 0.1 | GO:0010752 | regulation of cGMP-mediated signaling(GO:0010752) |
0.0 | 0.5 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
0.0 | 0.1 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
0.0 | 0.7 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.3 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
0.0 | 0.1 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
0.0 | 0.1 | GO:0071873 | response to norepinephrine(GO:0071873) |
0.0 | 0.1 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
0.0 | 0.1 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
0.0 | 0.2 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.0 | 0.2 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.0 | 0.2 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.0 | 0.1 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.0 | 0.8 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.4 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.0 | 0.3 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.0 | 0.1 | GO:0016114 | terpenoid biosynthetic process(GO:0016114) |
0.0 | 0.2 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.0 | 0.1 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.0 | 0.1 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
0.0 | 0.1 | GO:0006788 | heme oxidation(GO:0006788) |
0.0 | 0.6 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
0.0 | 0.2 | GO:0030259 | lipid glycosylation(GO:0030259) |
0.0 | 0.2 | GO:0097284 | hepatocyte apoptotic process(GO:0097284) |
0.0 | 0.2 | GO:0015074 | DNA integration(GO:0015074) |
0.0 | 0.1 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.0 | 0.2 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.0 | 0.1 | GO:0002829 | negative regulation of type 2 immune response(GO:0002829) |
0.0 | 0.1 | GO:0035814 | negative regulation of renal sodium excretion(GO:0035814) |
0.0 | 0.1 | GO:0002339 | B cell selection(GO:0002339) |
0.0 | 0.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.0 | 0.1 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
0.0 | 0.0 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.0 | 0.4 | GO:0003351 | epithelial cilium movement(GO:0003351) |
0.0 | 0.0 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
0.0 | 0.1 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
0.0 | 0.2 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.5 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
0.0 | 0.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.0 | 0.5 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
0.0 | 0.2 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.0 | 0.9 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.0 | 0.3 | GO:0033962 | cytoplasmic mRNA processing body assembly(GO:0033962) |
0.0 | 0.0 | GO:0032621 | interleukin-18 production(GO:0032621) |
0.0 | 0.3 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
0.0 | 0.4 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.0 | 0.0 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
0.0 | 0.0 | GO:1901642 | purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642) |
0.0 | 0.1 | GO:0030223 | neutrophil differentiation(GO:0030223) |
0.0 | 0.7 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.1 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.0 | 0.1 | GO:0046415 | urate metabolic process(GO:0046415) |
0.0 | 0.2 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
0.0 | 0.0 | GO:0038108 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) |
0.0 | 0.1 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
0.0 | 0.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 1.1 | GO:0006413 | translational initiation(GO:0006413) |
0.0 | 0.1 | GO:0042573 | retinoic acid metabolic process(GO:0042573) retinal metabolic process(GO:0042574) |
0.0 | 0.0 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
0.0 | 0.2 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
0.0 | 0.3 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
0.0 | 1.5 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
0.0 | 0.1 | GO:1901020 | negative regulation of calcium ion transmembrane transporter activity(GO:1901020) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.5 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
0.3 | 0.9 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
0.2 | 1.7 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.2 | 0.6 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
0.2 | 0.6 | GO:0005584 | collagen type I trimer(GO:0005584) |
0.2 | 0.5 | GO:1990047 | spindle matrix(GO:1990047) |
0.2 | 0.9 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.1 | 2.2 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.1 | 0.6 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
0.1 | 0.6 | GO:0043256 | laminin complex(GO:0043256) |
0.1 | 0.4 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
0.1 | 0.3 | GO:0000814 | ESCRT II complex(GO:0000814) |
0.1 | 0.5 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.1 | 0.4 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.1 | 1.0 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.1 | 0.6 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.1 | 0.4 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.1 | 0.4 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.1 | 0.6 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.1 | 0.5 | GO:0001940 | male pronucleus(GO:0001940) |
0.1 | 0.5 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.1 | 0.7 | GO:0045275 | respiratory chain complex III(GO:0045275) |
0.1 | 0.6 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.1 | 0.2 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.1 | 0.6 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
0.1 | 0.3 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.0 | 0.4 | GO:0033269 | internode region of axon(GO:0033269) |
0.0 | 0.3 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.0 | 0.3 | GO:0098536 | deuterosome(GO:0098536) |
0.0 | 0.5 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.0 | 0.7 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 2.1 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.3 | GO:0001520 | outer dense fiber(GO:0001520) |
0.0 | 0.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.0 | 0.7 | GO:0097470 | ribbon synapse(GO:0097470) |
0.0 | 0.1 | GO:0031983 | vesicle lumen(GO:0031983) |
0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.6 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 0.2 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.0 | 1.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.3 | GO:0005688 | U6 snRNP(GO:0005688) |
0.0 | 0.2 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 0.5 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 0.5 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 0.2 | GO:0005775 | vacuolar lumen(GO:0005775) |
0.0 | 0.4 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
0.0 | 0.2 | GO:0005642 | annulate lamellae(GO:0005642) |
0.0 | 0.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.0 | 0.1 | GO:0019815 | B cell receptor complex(GO:0019815) |
0.0 | 0.3 | GO:0031932 | TORC2 complex(GO:0031932) |
0.0 | 0.3 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.1 | GO:0072487 | MSL complex(GO:0072487) |
0.0 | 0.5 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.1 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.0 | 0.2 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.0 | 0.1 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
0.0 | 0.1 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.0 | 0.7 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.5 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.1 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
0.0 | 0.1 | GO:0031415 | NatA complex(GO:0031415) |
0.0 | 1.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 0.3 | GO:0031527 | filopodium membrane(GO:0031527) |
0.0 | 0.0 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.0 | 0.2 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
0.0 | 0.1 | GO:0061700 | nuclear pore outer ring(GO:0031080) GATOR2 complex(GO:0061700) |
0.0 | 1.4 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 0.2 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.9 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.5 | GO:0097546 | ciliary base(GO:0097546) |
0.0 | 0.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.1 | GO:0005832 | zona pellucida receptor complex(GO:0002199) chaperonin-containing T-complex(GO:0005832) |
0.0 | 0.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.5 | GO:0035651 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
0.4 | 1.7 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
0.3 | 1.6 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
0.3 | 0.9 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
0.3 | 0.9 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
0.3 | 0.9 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
0.3 | 1.0 | GO:0003998 | acylphosphatase activity(GO:0003998) |
0.2 | 0.7 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
0.2 | 1.0 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
0.2 | 2.0 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.2 | 0.5 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.2 | 0.5 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
0.2 | 1.1 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.1 | 0.4 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
0.1 | 0.6 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.1 | 0.4 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.1 | 0.4 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.1 | 0.6 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.1 | 1.7 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.1 | 0.3 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
0.1 | 0.3 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.1 | 0.4 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.1 | 0.4 | GO:0097003 | adipokinetic hormone receptor activity(GO:0097003) |
0.1 | 0.5 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.1 | 0.5 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.1 | 0.7 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.1 | 0.9 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.1 | 0.3 | GO:0000700 | mismatch base pair DNA N-glycosylase activity(GO:0000700) |
0.1 | 0.7 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.1 | 0.6 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.1 | 2.0 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 0.7 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.1 | 0.2 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
0.1 | 0.5 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.1 | 0.2 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.1 | 0.3 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.1 | 0.3 | GO:0042731 | PH domain binding(GO:0042731) |
0.1 | 0.4 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.0 | 0.2 | GO:0019808 | polyamine binding(GO:0019808) |
0.0 | 0.2 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.0 | 0.3 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.0 | 0.2 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.0 | 0.3 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.0 | 0.2 | GO:0004046 | aminoacylase activity(GO:0004046) |
0.0 | 0.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.0 | 1.0 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 0.2 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.0 | 0.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.0 | 0.3 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.0 | 0.4 | GO:1990405 | protein antigen binding(GO:1990405) |
0.0 | 0.2 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.0 | 0.2 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
0.0 | 0.9 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.0 | 0.6 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.4 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.0 | 0.6 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.0 | 0.1 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.0 | 0.2 | GO:0031419 | cobalamin binding(GO:0031419) |
0.0 | 0.1 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
0.0 | 0.1 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
0.0 | 0.5 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 0.1 | GO:0008142 | oxysterol binding(GO:0008142) |
0.0 | 0.2 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
0.0 | 0.4 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.0 | 0.2 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
0.0 | 0.6 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.1 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
0.0 | 0.3 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.1 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
0.0 | 0.3 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 0.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.0 | 0.5 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.1 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
0.0 | 0.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.3 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.0 | 0.2 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.0 | 0.7 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.0 | 0.2 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.0 | 0.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.0 | 0.1 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
0.0 | 1.5 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.6 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.1 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
0.0 | 0.1 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
0.0 | 1.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.1 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.0 | 0.1 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
0.0 | 0.3 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 0.0 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
0.0 | 0.3 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 0.2 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.0 | 0.8 | GO:0005507 | copper ion binding(GO:0005507) |
0.0 | 0.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.4 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 3.2 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.0 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.0 | 0.1 | GO:0001851 | complement component C3b binding(GO:0001851) |
0.0 | 0.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 1.0 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
0.0 | 0.5 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
0.0 | 0.6 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
0.0 | 0.2 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 0.5 | GO:0009055 | electron carrier activity(GO:0009055) |
0.0 | 0.1 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.0 | 0.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 0.1 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
0.0 | 1.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.7 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
0.0 | 0.5 | GO:0016504 | peptidase activator activity(GO:0016504) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.6 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 2.2 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 1.5 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
0.0 | 1.4 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.0 | 0.5 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 0.5 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 1.7 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 0.3 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.0 | 0.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.1 | PID_MYC_PATHWAY | C-MYC pathway |
0.0 | 1.4 | PID_FGF_PATHWAY | FGF signaling pathway |
0.0 | 1.7 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 0.5 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 0.3 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.6 | REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS | Genes involved in Hormone ligand-binding receptors |
0.1 | 1.3 | REACTOME_POL_SWITCHING | Genes involved in Polymerase switching |
0.1 | 0.5 | REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
0.1 | 0.9 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
0.1 | 0.6 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
0.1 | 0.9 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.0 | 1.7 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.6 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.0 | 2.7 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.4 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
0.0 | 0.5 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.0 | 0.4 | REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
0.0 | 0.9 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.0 | 1.1 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.4 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.0 | 0.3 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 1.3 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
0.0 | 0.5 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.0 | 0.7 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 0.2 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
0.0 | 0.2 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.0 | 0.6 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.0 | 2.7 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.0 | 0.5 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.0 | 2.1 | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
0.0 | 0.4 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
0.0 | 0.3 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.0 | 0.1 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.0 | 0.4 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.0 | 0.1 | REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
0.0 | 0.7 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.4 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.0 | 0.3 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 0.3 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
0.0 | 0.1 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.0 | 0.1 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.0 | 0.1 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
0.0 | 0.3 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |