Motif ID: Olig2_Olig3

Z-value: 0.777

Transcription factors associated with Olig2_Olig3:

Gene SymbolEntrez IDGene Name
Olig2 ENSMUSG00000039830.8 Olig2
Olig3 ENSMUSG00000045591.5 Olig3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Olig2mm10_v2_chr16_+_91225550_91225579-0.465.3e-02Click!
Olig3mm10_v2_chr10_+_19356558_19356565-0.116.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Olig2_Olig3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_92164666 4.863 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr3_-_154330543 3.368 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr19_-_53589067 3.253 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr1_-_186117251 3.080 ENSMUST00000045388.7
Lyplal1
lysophospholipase-like 1
chr1_+_12692430 2.624 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr16_-_44558864 2.616 ENSMUST00000023370.4
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr9_-_119825456 2.563 ENSMUST00000070617.7
Scn11a
sodium channel, voltage-gated, type XI, alpha
chr16_-_44558879 2.532 ENSMUST00000114634.1
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr2_-_105399286 2.323 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr3_+_125404292 2.184 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr17_-_62606679 2.110 ENSMUST00000163332.1
Efna5
ephrin A5
chr10_+_53596936 2.081 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr3_+_125404072 2.080 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr16_+_16213318 1.966 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
Pkp2


plakophilin 2


chr11_-_69920892 1.960 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr9_+_66946057 1.892 ENSMUST00000040917.7
ENSMUST00000127896.1
Rps27l

ribosomal protein S27-like

chr4_+_15957923 1.747 ENSMUST00000029879.8
ENSMUST00000149069.1
Nbn

nibrin

chr11_+_32276400 1.727 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr15_-_55548164 1.698 ENSMUST00000165356.1
Mrpl13
mitochondrial ribosomal protein L13
chr1_+_51987139 1.656 ENSMUST00000168302.1
Stat4
signal transducer and activator of transcription 4
chr1_+_110099295 1.528 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr3_-_63851251 1.523 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr9_+_106281061 1.506 ENSMUST00000072206.6
Poc1a
POC1 centriolar protein homolog A (Chlamydomonas)
chr10_-_117224480 1.427 ENSMUST00000020382.6
Yeats4
YEATS domain containing 4
chrM_+_5319 1.372 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr2_-_80129458 1.371 ENSMUST00000102653.1
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr10_+_97479470 1.337 ENSMUST00000105287.3
Dcn
decorin
chr5_-_100820929 1.330 ENSMUST00000117364.1
ENSMUST00000055245.6
Fam175a

family with sequence similarity 175, member A

chr4_+_11579647 1.235 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr8_+_85171322 1.233 ENSMUST00000076896.5
Gm6531
predicted gene 6531
chr1_-_166309585 1.226 ENSMUST00000168347.1
5330438I03Rik
RIKEN cDNA 5330438I03 gene
chr2_-_80128834 1.220 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr5_+_144255223 1.182 ENSMUST00000056578.6
Bri3
brain protein I3
chrX_-_74373260 1.133 ENSMUST00000073067.4
ENSMUST00000037967.5
Slc10a3

solute carrier family 10 (sodium/bile acid cotransporter family), member 3

chr14_+_65806066 1.130 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr7_-_139582790 1.109 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chrX_+_141475385 1.106 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5

collagen, type IV, alpha 5

chr1_+_175880775 1.095 ENSMUST00000039725.6
Exo1
exonuclease 1
chr1_-_178337774 1.095 ENSMUST00000037748.7
Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr11_+_100320596 1.069 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr10_-_92162753 1.065 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr13_+_23535411 1.030 ENSMUST00000080859.5
Hist1h3g
histone cluster 1, H3g
chr10_+_45067167 1.028 ENSMUST00000099858.2
Prep
prolyl endopeptidase
chr14_-_88123824 1.023 ENSMUST00000074245.3
Rps3a2
ribosomal protein S3A2
chr8_+_31089471 1.019 ENSMUST00000036631.7
ENSMUST00000170204.1
Dusp26

dual specificity phosphatase 26 (putative)

chr10_+_128015157 1.009 ENSMUST00000178041.1
ENSMUST00000026461.7
Prim1

DNA primase, p49 subunit

chr3_-_59220150 0.998 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr7_-_64392214 0.990 ENSMUST00000032735.5
Mphosph10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr2_-_174346712 0.988 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chrX_+_56786527 0.987 ENSMUST00000144600.1
Fhl1
four and a half LIM domains 1
chr15_-_91191733 0.981 ENSMUST00000069511.6
Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr17_+_46772635 0.979 ENSMUST00000071430.5
2310039H08Rik
RIKEN cDNA 2310039H08 gene
chr10_-_127522428 0.977 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr5_+_92925400 0.973 ENSMUST00000172706.1
Shroom3
shroom family member 3
chr11_-_9011111 0.967 ENSMUST00000020683.3
Hus1
Hus1 homolog (S. pombe)
chr17_+_46496753 0.958 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr11_+_117232254 0.919 ENSMUST00000106354.2
Sept9
septin 9
chr4_-_110292719 0.915 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_35000746 0.894 ENSMUST00000163360.1
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr2_-_132253227 0.888 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr19_+_20601958 0.872 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr14_+_103070216 0.871 ENSMUST00000022721.6
Cln5
ceroid-lipofuscinosis, neuronal 5
chrX_+_93286499 0.865 ENSMUST00000046565.7
ENSMUST00000113947.2
Arx

aristaless related homeobox

chr7_+_45216671 0.851 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr8_+_27260327 0.830 ENSMUST00000033880.5
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr11_-_101417615 0.795 ENSMUST00000070395.8
Aarsd1
alanyl-tRNA synthetase domain containing 1
chr2_+_155751117 0.784 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr9_+_76014855 0.773 ENSMUST00000008052.6
ENSMUST00000183425.1
ENSMUST00000183979.1
ENSMUST00000117981.2
Hmgcll1



3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1



chr3_+_102734496 0.772 ENSMUST00000029451.5
Tspan2
tetraspanin 2
chr14_+_74732384 0.756 ENSMUST00000176957.1
Esd
esterase D/formylglutathione hydrolase
chr14_+_74732297 0.754 ENSMUST00000022573.10
ENSMUST00000175712.1
Esd

esterase D/formylglutathione hydrolase

chr12_+_111971545 0.754 ENSMUST00000079009.5
Tdrd9
tudor domain containing 9
chr9_+_15520830 0.753 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr8_+_53511695 0.739 ENSMUST00000033920.4
Aga
aspartylglucosaminidase
chr9_-_27155418 0.716 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chr11_+_97029925 0.712 ENSMUST00000021249.4
Scrn2
secernin 2
chr18_-_15063560 0.698 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr18_+_34759551 0.694 ENSMUST00000097622.3
Fam53c
family with sequence similarity 53, member C
chr2_-_79456750 0.681 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr6_-_13871477 0.677 ENSMUST00000139231.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr14_-_47394253 0.671 ENSMUST00000177822.1
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr13_-_21440901 0.667 ENSMUST00000122872.1
ENSMUST00000151743.1
ENSMUST00000148071.1
Pgbd1


piggyBac transposable element derived 1


chr2_+_14873656 0.651 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2

calcium channel, voltage-dependent, beta 2 subunit

chr5_+_90768511 0.646 ENSMUST00000031319.6
Ppbp
pro-platelet basic protein
chr8_-_34146974 0.644 ENSMUST00000033910.8
Leprotl1
leptin receptor overlapping transcript-like 1
chr13_+_92354783 0.637 ENSMUST00000022218.4
Dhfr
dihydrofolate reductase
chr18_-_88894322 0.631 ENSMUST00000070116.5
ENSMUST00000125362.1
Socs6

suppressor of cytokine signaling 6

chr15_+_12321472 0.629 ENSMUST00000059680.5
Golph3
golgi phosphoprotein 3
chr15_-_5121172 0.628 ENSMUST00000090488.2
Gm10250
predicted pseudogene 10250
chr4_+_89137122 0.626 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr7_-_118584669 0.626 ENSMUST00000044195.4
Tmc7
transmembrane channel-like gene family 7
chr13_-_98492001 0.624 ENSMUST00000170205.1
Gm10320
predicted pseudogene 10320
chr19_-_36919606 0.619 ENSMUST00000057337.7
Fgfbp3
fibroblast growth factor binding protein 3
chr17_+_8182247 0.617 ENSMUST00000161898.1
Fgfr1op
Fgfr1 oncogene partner
chrX_-_145505136 0.615 ENSMUST00000112835.1
Amot
angiomotin
chr15_-_50882806 0.615 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr11_-_107189325 0.614 ENSMUST00000018577.7
ENSMUST00000106757.1
Nol11

nucleolar protein 11

chr9_-_48480540 0.613 ENSMUST00000034524.3
Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr5_+_76183880 0.611 ENSMUST00000031144.7
Tmem165
transmembrane protein 165
chr11_-_75796048 0.608 ENSMUST00000021209.7
Doc2b
double C2, beta
chr11_-_102365111 0.603 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr13_-_115090123 0.602 ENSMUST00000109226.3
Pelo
pelota homolog (Drosophila)
chr11_+_69991633 0.601 ENSMUST00000108592.1
Gabarap
gamma-aminobutyric acid receptor associated protein
chr14_+_47472628 0.591 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr10_+_75589363 0.588 ENSMUST00000072217.2
Ggt5
gamma-glutamyltransferase 5
chr18_-_51865881 0.583 ENSMUST00000091905.2
Gm4950
predicted pseudogene 4950
chr3_-_84155762 0.580 ENSMUST00000047368.6
Mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr7_-_45092130 0.577 ENSMUST00000148175.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chrX_+_7579666 0.574 ENSMUST00000115740.1
ENSMUST00000115739.1
Foxp3

forkhead box P3

chr6_-_72345144 0.572 ENSMUST00000070345.3
Usp39
ubiquitin specific peptidase 39
chr10_+_11609256 0.566 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr9_-_88719798 0.559 ENSMUST00000113110.3
Gm2382
predicted gene 2382
chr10_+_110920170 0.558 ENSMUST00000020403.5
Csrp2
cysteine and glycine-rich protein 2
chr13_+_108046411 0.558 ENSMUST00000095458.4
Smim15
small integral membrane protein 15
chr2_-_101649501 0.551 ENSMUST00000160722.1
ENSMUST00000160037.1
ENSMUST00000078494.5
B230118H07Rik

Rag1
RIKEN cDNA B230118H07 gene

recombination activating gene 1
chr16_-_4719148 0.548 ENSMUST00000115851.3
Nmral1
NmrA-like family domain containing 1
chr3_-_33082004 0.540 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr7_-_126704816 0.535 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr3_-_46447939 0.534 ENSMUST00000166505.1
Pabpc4l
poly(A) binding protein, cytoplasmic 4-like
chr5_-_65391408 0.527 ENSMUST00000057885.6
Rpl9
ribosomal protein L9
chr19_+_7268296 0.526 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr1_-_53352637 0.521 ENSMUST00000027264.3
ENSMUST00000123519.2
Asnsd1

asparagine synthetase domain containing 1

chr11_-_69920581 0.520 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr11_-_5878207 0.514 ENSMUST00000102922.3
Pold2
polymerase (DNA directed), delta 2, regulatory subunit
chr4_-_87230435 0.510 ENSMUST00000107157.2
Slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr2_+_157737401 0.508 ENSMUST00000029178.6
Ctnnbl1
catenin, beta like 1
chr18_-_40219324 0.504 ENSMUST00000025364.4
Yipf5
Yip1 domain family, member 5
chr3_+_87906842 0.501 ENSMUST00000159492.1
Hdgf
hepatoma-derived growth factor
chr2_-_71367749 0.498 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr9_+_37401897 0.490 ENSMUST00000115048.1
Robo4
roundabout homolog 4 (Drosophila)
chr7_+_30314810 0.487 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
Syne4



spectrin repeat containing, nuclear envelope family member 4



chr17_-_48432723 0.486 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr2_+_164456936 0.482 ENSMUST00000109352.1
Sys1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr2_+_157279026 0.479 ENSMUST00000116380.2
Rpn2
ribophorin II
chr12_+_108410542 0.478 ENSMUST00000054955.7
Eml1
echinoderm microtubule associated protein like 1
chr5_-_65391380 0.469 ENSMUST00000120094.1
ENSMUST00000118543.1
ENSMUST00000127874.1
Rpl9


ribosomal protein L9


chrX_+_36328353 0.461 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr6_+_17636983 0.459 ENSMUST00000015877.7
Capza2
capping protein (actin filament) muscle Z-line, alpha 2
chr10_-_117746356 0.455 ENSMUST00000079041.5
Slc35e3
solute carrier family 35, member E3
chr2_+_157279065 0.450 ENSMUST00000029171.5
Rpn2
ribophorin II
chr1_-_79440039 0.450 ENSMUST00000049972.4
Scg2
secretogranin II
chr14_+_26514554 0.448 ENSMUST00000104927.1
Gm2178
predicted gene 2178
chr3_+_121291725 0.446 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr10_+_128790903 0.445 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr15_-_99651580 0.444 ENSMUST00000171908.1
ENSMUST00000171702.1
ENSMUST00000109581.2
ENSMUST00000169810.1
ENSMUST00000023756.5
Racgap1




Rac GTPase-activating protein 1




chr16_-_46155077 0.443 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr11_-_53480178 0.439 ENSMUST00000104955.2
Sowaha
sosondowah ankyrin repeat domain family member A
chr14_+_47472547 0.438 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr11_-_87404380 0.438 ENSMUST00000067692.6
Rad51c
RAD51 homolog C
chr7_-_45092198 0.428 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
Rcn3


reticulocalbin 3, EF-hand calcium binding domain


chr13_-_18031616 0.418 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr3_+_60877002 0.418 ENSMUST00000099086.2
Gm8325
predicted pseudogene 8325
chr11_+_71749914 0.418 ENSMUST00000150531.1
Wscd1
WSC domain containing 1
chr9_+_107580117 0.412 ENSMUST00000093785.4
Nat6
N-acetyltransferase 6
chr7_+_127904079 0.404 ENSMUST00000071056.7
Bckdk
branched chain ketoacid dehydrogenase kinase
chr7_-_126704736 0.401 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr19_+_55898553 0.400 ENSMUST00000148666.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr9_+_37401993 0.387 ENSMUST00000115046.1
ENSMUST00000102895.4
Robo4

roundabout homolog 4 (Drosophila)

chr10_+_80054029 0.383 ENSMUST00000097227.3
Gpx4
glutathione peroxidase 4
chr9_+_48450327 0.377 ENSMUST00000165252.1
Gm5616
predicted gene 5616
chr17_-_34615965 0.371 ENSMUST00000097345.3
ENSMUST00000015611.7
Egfl8

EGF-like domain 8

chr12_-_80132802 0.361 ENSMUST00000180643.1
2310015A10Rik
RIKEN cDNA 2310015A10 gene
chr6_+_48684570 0.358 ENSMUST00000067506.7
ENSMUST00000119575.1
ENSMUST00000114527.2
ENSMUST00000121957.1
ENSMUST00000090070.5
Gimap4




GTPase, IMAP family member 4




chr4_+_139233383 0.355 ENSMUST00000042675.7
Capzb
capping protein (actin filament) muscle Z-line, beta
chr7_-_44748306 0.352 ENSMUST00000118162.1
ENSMUST00000140599.2
ENSMUST00000120798.1
Zfp473


zinc finger protein 473


chr15_+_31568851 0.345 ENSMUST00000070918.6
Cmbl
carboxymethylenebutenolidase-like (Pseudomonas)
chr1_-_182282738 0.344 ENSMUST00000035295.5
Degs1
degenerative spermatocyte homolog 1 (Drosophila)
chr8_+_33428709 0.343 ENSMUST00000059351.7
5930422O12Rik
RIKEN cDNA 5930422O12 gene
chr8_+_60655540 0.342 ENSMUST00000034066.3
Mfap3l
microfibrillar-associated protein 3-like
chr13_-_56895737 0.339 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chrX_-_53608979 0.333 ENSMUST00000123034.1
Gm14597
predicted gene 14597
chr2_+_127587214 0.333 ENSMUST00000028852.6
Mrps5
mitochondrial ribosomal protein S5
chr10_+_128747850 0.326 ENSMUST00000163377.2
Wibg
within bgcn homolog (Drosophila)
chr1_+_74391479 0.318 ENSMUST00000027367.7
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr4_+_86930691 0.317 ENSMUST00000164590.1
Acer2
alkaline ceramidase 2
chr8_+_4253067 0.313 ENSMUST00000011981.3
Snapc2
small nuclear RNA activating complex, polypeptide 2
chr4_+_41762309 0.306 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr3_+_94443315 0.304 ENSMUST00000029786.7
ENSMUST00000098876.3
Mrpl9

mitochondrial ribosomal protein L9

chr16_-_91931643 0.303 ENSMUST00000023677.3
Atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr15_+_99006056 0.302 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr3_-_151762906 0.302 ENSMUST00000046739.4
Ifi44l
interferon-induced protein 44 like
chr14_+_28511344 0.300 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr7_+_25681158 0.296 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr5_-_33657889 0.293 ENSMUST00000019439.7
Tmem129
transmembrane protein 129
chr12_+_55398775 0.287 ENSMUST00000021412.8
Psma6
proteasome (prosome, macropain) subunit, alpha type 6
chr5_+_124598749 0.284 ENSMUST00000130912.1
ENSMUST00000100706.3
Tctn2

tectonic family member 2

chr10_+_14523062 0.284 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr18_+_35771488 0.283 ENSMUST00000170693.1
Ube2d2a
ubiquitin-conjugating enzyme E2D 2A
chr10_+_127041931 0.281 ENSMUST00000006915.7
ENSMUST00000120542.1
Mettl1

methyltransferase like 1

chr9_+_108936648 0.281 ENSMUST00000026743.8
Uqcrc1
ubiquinol-cytochrome c reductase core protein 1
chr2_+_131133497 0.276 ENSMUST00000110225.1
Gm11037
predicted gene 11037
chr12_-_113361232 0.273 ENSMUST00000103423.1
Ighg3
Immunoglobulin heavy constant gamma 3
chr16_-_95990890 0.271 ENSMUST00000117044.1
ENSMUST00000023630.7
Psmg1

proteasome (prosome, macropain) assembly chaperone 1

chr6_+_48684544 0.270 ENSMUST00000118802.1
Gimap4
GTPase, IMAP family member 4
chr4_+_9269285 0.263 ENSMUST00000038841.7
Clvs1
clavesin 1
chr2_+_180456234 0.262 ENSMUST00000038259.6
Slco4a1
solute carrier organic anion transporter family, member 4a1
chr5_-_108434373 0.260 ENSMUST00000049628.9
ENSMUST00000118632.1
Atp5k

ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e

chr3_-_121171678 0.259 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chr7_-_138397704 0.257 ENSMUST00000160436.1
Tcerg1l
transcription elongation regulator 1-like
chr5_+_8893677 0.255 ENSMUST00000003717.8
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.7 2.0 GO:0002159 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496)
0.5 3.1 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.4 2.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 1.6 GO:0006545 glycine biosynthetic process(GO:0006545)
0.4 1.5 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.4 1.1 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.3 1.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 1.7 GO:0015671 oxygen transport(GO:0015671)
0.3 1.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.3 1.0 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.3 1.0 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.3 0.9 GO:0006272 leading strand elongation(GO:0006272)
0.3 0.9 GO:0021759 globus pallidus development(GO:0021759)
0.3 0.8 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.3 0.8 GO:0050819 negative regulation of coagulation(GO:0050819)
0.3 1.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 1.5 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 0.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 0.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 0.6 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.2 0.8 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 0.6 GO:0032829 tolerance induction to self antigen(GO:0002513) positive regulation of T cell anergy(GO:0002669) negative regulation of T cell cytokine production(GO:0002725) positive regulation of lymphocyte anergy(GO:0002913) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 1.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.1 GO:0032796 uropod organization(GO:0032796)
0.2 0.6 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.2 4.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 0.7 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 2.1 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 1.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 0.6 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.2 0.8 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.1 0.6 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.9 GO:1904426 positive regulation of GTP binding(GO:1904426)
0.1 2.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.8 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.5 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.4 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.6 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.6 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.1 0.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 1.0 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.1 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.4 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.1 1.0 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.3 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 3.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:0061349 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.1 0.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.3 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 2.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.3 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.3 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.1 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.5 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.2 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.1 0.2 GO:0015866 ADP transport(GO:0015866)
0.1 1.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.5 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 1.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.2 GO:1990859 cellular response to endothelin(GO:1990859)
0.1 1.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.6 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.4 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 0.7 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:1902309 regulation of peptidyl-serine dephosphorylation(GO:1902308) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.5 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.9 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 2.5 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.3 GO:0043652 skeletal muscle satellite cell activation(GO:0014719) skeletal muscle satellite cell differentiation(GO:0014816) engulfment of apoptotic cell(GO:0043652) recognition of apoptotic cell(GO:0043654)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 1.5 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.4 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.6 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.9 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 1.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0046697 decidualization(GO:0046697)
0.0 0.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.0 0.2 GO:0060325 head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
0.0 0.2 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0072236 DCT cell differentiation(GO:0072069) metanephric loop of Henle development(GO:0072236) metanephric DCT cell differentiation(GO:0072240)
0.0 1.1 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.6 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.1 GO:0007632 visual behavior(GO:0007632)
0.0 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.0 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.2 GO:0050667 drug metabolic process(GO:0017144) homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.5 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.6 GO:0050868 negative regulation of T cell activation(GO:0050868)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0044299 C-fiber(GO:0044299)
0.6 3.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.3 1.0 GO:0034457 Mpp10 complex(GO:0034457)
0.3 0.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 1.7 GO:0030870 Mre11 complex(GO:0030870)
0.3 0.9 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 1.0 GO:0070552 BRISC complex(GO:0070552)
0.2 2.5 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 1.7 GO:0005833 hemoglobin complex(GO:0005833)
0.2 0.6 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 2.7 GO:0030057 desmosome(GO:0030057)
0.2 1.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 2.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 1.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.0 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.9 GO:0005775 vacuolar lumen(GO:0005775)
0.1 0.8 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 1.1 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 1.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.4 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 5.1 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0033391 chromatoid body(GO:0033391)
0.1 0.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.4 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.9 GO:0031105 septin complex(GO:0031105)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.3 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) small ribosomal subunit(GO:0015935)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.5 2.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 1.5 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.4 2.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 1.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 1.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 1.0 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.3 3.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 1.8 GO:0008494 translation activator activity(GO:0008494)
0.3 0.9 GO:0032139 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.3 1.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 1.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.3 0.8 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.6 GO:0051870 methotrexate binding(GO:0051870)
0.2 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 0.8 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 0.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 2.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 0.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 2.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.1 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.5 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.3 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.3 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.3 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 0.3 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.6 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.3 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.9 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.4 GO:0000150 recombinase activity(GO:0000150)
0.1 1.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.9 GO:0005537 mannose binding(GO:0005537)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 1.0 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) purinergic receptor activity(GO:0035586)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 3.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.0 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.9 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.0 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.7 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 2.6 PID_BARD1_PATHWAY BARD1 signaling events
0.1 2.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 0.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID_ATM_PATHWAY ATM pathway
0.0 1.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.2 PID_ATR_PATHWAY ATR signaling pathway
0.0 3.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.1 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.8 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.2 2.4 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.1 5.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 4.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 2.5 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 0.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.8 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 2.1 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.0 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 2.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 2.2 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA