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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_+_102010138	3.980	ENSMUST00000066187.4	Nhlh2	nescient helix loop helix 2
chr12_+_55598917	3.764	ENSMUST00000051857.3	Insm2	insulinoma-associated 2
chr6_-_23248264	3.000	ENSMUST00000031709.5	Fezf1	Fez family zinc finger 1
chr18_+_57468478	2.889	ENSMUST00000091892.2	Ctxn3	cortexin 3
chr10_-_64090265	2.601	ENSMUST00000105439.1	Lrrtm3	leucine rich repeat transmembrane neuronal 3
chr6_+_4755327	2.516	ENSMUST00000176551.1	Peg10	paternally expressed 10
chr1_-_158958367	2.074	ENSMUST00000159861.2	Pappa2	pappalysin 2
chr10_-_64090241	1.786	ENSMUST00000133588.1	Lrrtm3	leucine rich repeat transmembrane neuronal 3
chr14_+_68083853	1.708	ENSMUST00000022639.7	Nefl	neurofilament, light polypeptide
chr10_-_112928974	1.171	ENSMUST00000099276.2	Atxn7l3b	ataxin 7-like 3B
chr8_+_58911755	1.070	ENSMUST00000062978.6	BC030500	cDNA sequence BC030500
chr19_-_57197496	0.956	ENSMUST00000111544.1	Ablim1	actin-binding LIM protein 1
chr7_+_75848338	0.954	ENSMUST00000092073.5 ENSMUST00000171155.2	Klhl25	kelch-like 25
chr9_-_114844090	0.827	ENSMUST00000047013.3	Cmtm8	CKLF-like MARVEL transmembrane domain containing 8
chr19_-_57197377	0.751	ENSMUST00000111546.1	Ablim1	actin-binding LIM protein 1
chr12_-_84698769	0.748	ENSMUST00000095550.2	Syndig1l	synapse differentiation inducing 1 like
chr2_-_72986716	0.693	ENSMUST00000112062.1	Gm11084	predicted gene 11084
chr13_+_93304940	0.660	ENSMUST00000109497.1 ENSMUST00000109498.1 ENSMUST00000060490.4 ENSMUST00000109492.1 ENSMUST00000109496.1 ENSMUST00000109495.1	Homer1	homer homolog 1 (Drosophila)
chr19_-_57197556	0.636	ENSMUST00000099294.2	Ablim1	actin-binding LIM protein 1
chr3_+_8509477	0.561	ENSMUST00000029002.7	Stmn2	stathmin-like 2
chrX_+_134404780	0.560	ENSMUST00000113224.2 ENSMUST00000113226.1	Drp2	dystrophin related protein 2
chr7_-_127448993	0.554	ENSMUST00000106299.1	Zfp689	zinc finger protein 689
chr19_-_57197435	0.536	ENSMUST00000111550.1	Ablim1	actin-binding LIM protein 1
chr1_+_165302625	0.534	ENSMUST00000111450.1	Gpr161	G protein-coupled receptor 161
chr7_-_127449109	0.532	ENSMUST00000053392.4	Zfp689	zinc finger protein 689
chr13_+_93304799	0.511	ENSMUST00000080127.5	Homer1	homer homolog 1 (Drosophila)
chr6_-_23132981	0.506	ENSMUST00000031707.7	Aass	aminoadipate-semialdehyde synthase
chr3_+_125404072	0.493	ENSMUST00000173932.1	Ndst4	N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr7_+_45627482	0.491	ENSMUST00000057927.7	Rasip1	Ras interacting protein 1
chr3_+_125404292	0.480	ENSMUST00000144344.1	Ndst4	N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr4_+_62965560	0.475	ENSMUST00000030043.6 ENSMUST00000107415.1 ENSMUST00000064814.5	Zfp618	zinc finger protein 618
chr18_-_72351029	0.464	ENSMUST00000114943.3	Dcc	deleted in colorectal carcinoma
chr15_-_42676967	0.460	ENSMUST00000022921.5	Angpt1	angiopoietin 1
chrX_+_134404543	0.454	ENSMUST00000113228.1 ENSMUST00000153424.1	Drp2	dystrophin related protein 2
chr18_-_72351009	0.440	ENSMUST00000073379.5	Dcc	deleted in colorectal carcinoma
chr12_+_72441933	0.440	ENSMUST00000161284.1	Lrrc9	leucine rich repeat containing 9
chr2_-_168767136	0.438	ENSMUST00000029061.5 ENSMUST00000103074.1	Sall4	sal-like 4 (Drosophila)
chrX_+_56609751	0.416	ENSMUST00000144068.1	Slc9a6	solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr6_+_29853746	0.412	ENSMUST00000064872.6 ENSMUST00000152581.1 ENSMUST00000176265.1 ENSMUST00000154079.1	Ahcyl2	S-adenosylhomocysteine hydrolase-like 2
chr1_+_191717834	0.409	ENSMUST00000110855.1 ENSMUST00000133076.1	Lpgat1	lysophosphatidylglycerol acyltransferase 1
chr1_-_51941261	0.352	ENSMUST00000097103.3	Gm8420	predicted gene 8420
chr2_-_32451396	0.338	ENSMUST00000028160.8 ENSMUST00000113310.2	Slc25a25	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr3_-_33082004	0.334	ENSMUST00000108225.3	Pex5l	peroxisomal biogenesis factor 5-like
chr4_-_97584605	0.317	ENSMUST00000107067.1	E130114P18Rik	RIKEN cDNA E130114P18 gene
chr12_+_72441852	0.310	ENSMUST00000162159.1	Lrrc9	leucine rich repeat containing 9
chrX_-_51205990	0.305	ENSMUST00000114876.2	Mbnl3	muscleblind-like 3 (Drosophila)
chr4_-_97584612	0.305	ENSMUST00000107068.2	E130114P18Rik	RIKEN cDNA E130114P18 gene
chr19_+_26750939	0.297	ENSMUST00000175953.1	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_5724304	0.296	ENSMUST00000108380.1	Fam110b	family with sequence similarity 110, member B
chr1_-_54194048	0.282	ENSMUST00000120904.1	Hecw2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr3_-_79842662	0.265	ENSMUST00000029568.1	Tmem144	transmembrane protein 144
chr8_-_8660773	0.249	ENSMUST00000001319.7	Efnb2	ephrin B2
chr8_-_58911627	0.242	ENSMUST00000077447.4	Galntl6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr2_+_163602331	0.232	ENSMUST00000152135.1	Ttpal	tocopherol (alpha) transfer protein-like
chr2_-_92392634	0.227	ENSMUST00000111279.2	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1
chr6_-_56704673	0.212	ENSMUST00000170382.2	Lsm5	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr5_+_92683625	0.206	ENSMUST00000168878.1	Shroom3	shroom family member 3
chr11_+_120232921	0.204	ENSMUST00000122148.1 ENSMUST00000044985.7	Bahcc1	BAH domain and coiled-coil containing 1
chr12_-_46818749	0.201	ENSMUST00000021438.6	Nova1	neuro-oncological ventral antigen 1
chr9_+_59589288	0.195	ENSMUST00000121266.1 ENSMUST00000118164.1	Celf6	CUGBP, Elav-like family member 6
chr8_+_127064022	0.187	ENSMUST00000160272.1 ENSMUST00000079777.5 ENSMUST00000162907.1	Pard3	par-3 (partitioning defective 3) homolog (C. elegans)
chr2_-_168767029	0.186	ENSMUST00000075044.3	Sall4	sal-like 4 (Drosophila)
chr16_+_32430895	0.184	ENSMUST00000115137.1 ENSMUST00000079791.4	Pcyt1a	phosphate cytidylyltransferase 1, choline, alpha isoform
chr2_+_130277157	0.178	ENSMUST00000028890.8 ENSMUST00000159373.1	Nop56	NOP56 ribonucleoprotein
chr12_-_80260091	0.172	ENSMUST00000167327.1	Actn1	actinin, alpha 1
chr2_+_163602294	0.162	ENSMUST00000171696.1 ENSMUST00000109408.3	Ttpal	tocopherol (alpha) transfer protein-like
chr1_-_54438940	0.159	ENSMUST00000041638.6	Gtf3c3	general transcription factor IIIC, polypeptide 3
chr8_-_91801547	0.159	ENSMUST00000093312.4	Irx3	Iroquois related homeobox 3 (Drosophila)
chr11_+_4902212	0.152	ENSMUST00000142543.1	Thoc5	THO complex 5
chr8_+_127064107	0.147	ENSMUST00000162536.1 ENSMUST00000026921.6 ENSMUST00000162665.1 ENSMUST00000160766.1 ENSMUST00000162602.1 ENSMUST00000162531.1 ENSMUST00000160581.1 ENSMUST00000161355.1 ENSMUST00000159537.1	Pard3	par-3 (partitioning defective 3) homolog (C. elegans)
chr2_-_25224653	0.145	ENSMUST00000043584.4	Tubb4b	tubulin, beta 4B class IVB
chr19_-_32061438	0.141	ENSMUST00000096119.4	Asah2	N-acylsphingosine amidohydrolase 2
chr4_+_109343029	0.140	ENSMUST00000030281.5	Eps15	epidermal growth factor receptor pathway substrate 15
chr16_+_32431225	0.136	ENSMUST00000115140.1	Pcyt1a	phosphate cytidylyltransferase 1, choline, alpha isoform
chr7_+_67655414	0.135	ENSMUST00000107470.1	Ttc23	tetratricopeptide repeat domain 23
chr9_-_50739365	0.126	ENSMUST00000117093.1 ENSMUST00000121634.1	Dixdc1	DIX domain containing 1
chr3_+_94372794	0.120	ENSMUST00000029795.3	Rorc	RAR-related orphan receptor gamma
chr9_-_29963112	0.118	ENSMUST00000075069.4	Ntm	neurotrimin
chr7_-_116084635	0.117	ENSMUST00000111755.3	Gm4353	predicted gene 4353
chr3_+_68572245	0.115	ENSMUST00000170788.2	Schip1	schwannomin interacting protein 1
chr11_+_97315716	0.102	ENSMUST00000019026.3 ENSMUST00000132168.1	Mrpl45	mitochondrial ribosomal protein L45
chr18_+_15832772	0.089	ENSMUST00000079733.5	Gm10036	predicted gene 10036
chr17_-_24479034	0.086	ENSMUST00000179163.1 ENSMUST00000070888.6	Mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae)
chr8_-_79399513	0.074	ENSMUST00000066091.7 ENSMUST00000109885.1 ENSMUST00000066081.3	Smad1	SMAD family member 1
chr7_+_67647405	0.070	ENSMUST00000032774.8 ENSMUST00000107471.1	Ttc23	tetratricopeptide repeat domain 23
chr9_-_59146210	0.070	ENSMUST00000085631.2	Gm7589	predicted gene 7589
chr17_+_55986494	0.061	ENSMUST00000011733.8	Fsd1	fibronectin type 3 and SPRY domain-containing protein
chr17_+_56990264	0.056	ENSMUST00000002735.7	Clpp	ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit
chr11_-_60036917	0.055	ENSMUST00000102692.3	Pemt	phosphatidylethanolamine N-methyltransferase
chr19_-_37178011	0.051	ENSMUST00000133988.1	Cpeb3	cytoplasmic polyadenylation element binding protein 3
chr9_+_54980880	0.039	ENSMUST00000093844.3	Chrna5	cholinergic receptor, nicotinic, alpha polypeptide 5
chr17_-_46440099	0.027	ENSMUST00000166852.1	Gm5093	predicted gene 5093
chr5_+_144100387	0.026	ENSMUST00000041804.7	Lmtk2	lemur tyrosine kinase 2
chr1_-_89933290	0.026	ENSMUST00000036954.7	Gbx2	gastrulation brain homeobox 2
chr7_-_104950441	0.026	ENSMUST00000179862.1	Gm5900	predicted pseudogene 5900
chr16_-_95459245	0.021	ENSMUST00000176345.1 ENSMUST00000121809.2 ENSMUST00000118113.1 ENSMUST00000122199.1	Erg	avian erythroblastosis virus E-26 (v-ets) oncogene related
chr19_+_31082841	0.013	ENSMUST00000066039.6	Cstf2t	cleavage stimulation factor, 3' pre-RNA subunit 2, tau
chr4_+_117849361	0.007	ENSMUST00000163288.1	Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.5	3.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.3	4.4	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
0.2	0.6	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.2	0.5	GO:0006553	lysine metabolic process(GO:0006553)
0.2	0.8	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2	0.5	GO:0030210	heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.2	0.9	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
0.1	4.0	GO:0007617	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1	0.3	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	1.2	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.1	0.3	GO:0003383	apical constriction(GO:0003383)
0.1	0.4	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.5	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.3	GO:0051461	protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.4	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.6	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	2.5	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0	0.3	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.2	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0	2.5	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.4	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.2	GO:0072086	specification of loop of Henle identity(GO:0072086)
0.0	0.2	GO:0045650	negative regulation of macrophage differentiation(GO:0045650) negative regulation of DNA damage checkpoint(GO:2000002)
0.0	0.3	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0002182	cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0	0.3	GO:0014823	response to activity(GO:0014823)
0.0	0.1	GO:0072615	interleukin-17 secretion(GO:0072615)
0.0	0.8	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.2	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.0	GO:0021546	rhombomere development(GO:0021546)
0.0	0.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.2	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.9	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	0.2	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.1	0.3	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1	0.9	GO:0032584	growth cone membrane(GO:0032584)
0.1	0.2	GO:0044302	dentate gyrus mossy fiber(GO:0044302)
0.1	0.4	GO:0044308	axonal spine(GO:0044308)
0.0	0.2	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.3	GO:0033269	internode region of axon(GO:0033269)
0.0	0.3	GO:0042587	glycogen granule(GO:0042587)
0.0	0.2	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	2.9	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.8	GO:0043034	costamere(GO:0043034)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	5.4	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.3	GO:0071564	npBAF complex(GO:0071564)
0.0	0.2	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	1.0	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0005042	netrin receptor activity(GO:0005042)
0.1	1.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	1.2	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	0.8	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.3	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1	1.7	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.3	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1	4.0	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	0.4	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.4	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	0.2	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0	4.4	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.3	GO:0015217	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0	0.5	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	2.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.5	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	3.8	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	2.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.2	GO:1990226	histone methyltransferase binding(GO:1990226)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.5	PID_MYC_ACTIV_PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.9	PID_NETRIN_PATHWAY	Netrin-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.8	REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.1	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.7	REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.4	REACTOME_ACYL_CHAIN_REMODELLING_OF_PG	Genes involved in Acyl chain remodelling of PG
0.0	1.0	REACTOME_HS_GAG_BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME_TIE2_SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME_SYNTHESIS_OF_PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME_NEPHRIN_INTERACTIONS	Genes involved in Nephrin interactions

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