Motif ID: Osr2_Osr1

Z-value: 1.024

Transcription factors associated with Osr2_Osr1:

Gene SymbolEntrez IDGene Name
Osr1 ENSMUSG00000048387.7 Osr1
Osr2 ENSMUSG00000022330.4 Osr2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Osr1mm10_v2_chr12_+_9574437_95744480.262.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Osr2_Osr1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_107497762 2.252 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr10_+_4611971 2.203 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr5_+_107497718 2.132 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr10_-_109823585 2.067 ENSMUST00000161582.1
Nav3
neuron navigator 3
chr4_-_134254076 1.862 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr1_-_43163891 1.589 ENSMUST00000008280.7
Fhl2
four and a half LIM domains 2
chr15_-_43869993 1.561 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chrY_+_90785442 1.526 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr4_+_13743424 1.467 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_170010744 1.423 ENSMUST00000178789.1
Gm21887
predicted gene, 21887
chr6_+_141524379 1.328 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr4_+_135963742 1.234 ENSMUST00000149636.1
ENSMUST00000143304.1
Gale

galactose-4-epimerase, UDP

chr2_-_80128834 1.163 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr4_+_102087543 1.158 ENSMUST00000106911.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr6_-_59024470 1.085 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr6_-_142571303 0.981 ENSMUST00000032374.7
Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
chr7_-_57509995 0.966 ENSMUST00000068456.6
Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr10_+_82058417 0.952 ENSMUST00000105313.1
Zfp873
zinc finger protein 873
chr6_-_59024340 0.794 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr2_+_136892168 0.778 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr4_+_135963720 0.745 ENSMUST00000102541.3
Gale
galactose-4-epimerase, UDP
chr7_+_126950687 0.733 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr15_-_78718113 0.711 ENSMUST00000088592.4
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr7_-_123500449 0.696 ENSMUST00000042470.7
ENSMUST00000128217.1
Zkscan2

zinc finger with KRAB and SCAN domains 2

chr3_-_127225847 0.668 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chrY_+_90784738 0.651 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr9_-_86546795 0.617 ENSMUST00000167814.1
Gm17530
predicted gene, 17530
chr14_-_20480106 0.609 ENSMUST00000065504.9
ENSMUST00000100844.4
Anxa7

annexin A7

chr15_-_20666750 0.608 ENSMUST00000052910.4
Acot10
acyl-CoA thioesterase 10
chr8_+_3621529 0.582 ENSMUST00000156380.2
Pet100
PET100 homolog (S. cerevisiae)
chr16_+_91729281 0.578 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
Itsn1






intersectin 1 (SH3 domain protein 1A)






chr9_-_50739365 0.576 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr8_+_12984246 0.554 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr16_-_91728701 0.540 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr18_-_31317043 0.537 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chr2_+_131950855 0.535 ENSMUST00000110170.1
ENSMUST00000110172.2
ENSMUST00000110171.2
Prnd


prion protein dublet


chr6_-_144209448 0.527 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr19_+_27217011 0.519 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr3_-_127225917 0.514 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr19_-_57008187 0.508 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr16_+_91729436 0.507 ENSMUST00000113993.1
Itsn1
intersectin 1 (SH3 domain protein 1A)
chr4_+_134496996 0.506 ENSMUST00000095074.3
Paqr7
progestin and adipoQ receptor family member VII
chr6_-_144209471 0.497 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr9_-_53610329 0.495 ENSMUST00000034547.5
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr6_-_144209558 0.488 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr4_+_139622842 0.458 ENSMUST00000039818.9
Aldh4a1
aldehyde dehydrogenase 4 family, member A1
chr4_+_43383449 0.455 ENSMUST00000135216.1
ENSMUST00000152322.1
Rusc2

RUN and SH3 domain containing 2

chr5_+_123930675 0.421 ENSMUST00000094320.3
ENSMUST00000165148.1
Ccdc62

coiled-coil domain containing 62

chr9_-_96719404 0.412 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr5_+_76529303 0.393 ENSMUST00000087133.4
ENSMUST00000113493.1
ENSMUST00000049469.6
Exoc1


exocyst complex component 1


chr2_+_176831140 0.393 ENSMUST00000122218.2
ENSMUST00000126726.1
Gm14408

predicted gene 14408

chr16_-_91728975 0.392 ENSMUST00000073466.6
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr18_+_38296805 0.390 ENSMUST00000171461.1
Rnf14
ring finger protein 14
chr9_+_3532295 0.390 ENSMUST00000115733.1
Gucy1a2
guanylate cyclase 1, soluble, alpha 2
chr6_+_51523901 0.390 ENSMUST00000049152.8
Snx10
sorting nexin 10
chr9_-_96719549 0.378 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr7_+_97842917 0.376 ENSMUST00000033040.5
Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr3_-_89322883 0.370 ENSMUST00000029673.5
Efna3
ephrin A3
chr5_+_19227046 0.369 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_16378231 0.357 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr2_+_83644435 0.355 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr10_+_74967164 0.351 ENSMUST00000037813.4
Gnaz
guanine nucleotide binding protein, alpha z subunit
chr2_-_156180135 0.350 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
Rbm39




RNA binding motif protein 39




chr4_+_134496966 0.349 ENSMUST00000134506.1
ENSMUST00000136171.1
ENSMUST00000125330.1
Paqr7


progestin and adipoQ receptor family member VII


chr7_-_30743681 0.347 ENSMUST00000182634.1
Gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr19_-_6067785 0.341 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
Tm7sf2






transmembrane 7 superfamily member 2






chr4_-_119383732 0.330 ENSMUST00000044781.2
ENSMUST00000084307.3
Ccdc30

coiled-coil domain containing 30

chr12_-_110682606 0.330 ENSMUST00000070659.5
1700001K19Rik
RIKEN cDNA 1700001K19 gene
chr1_+_179546303 0.329 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr7_+_44849216 0.321 ENSMUST00000054343.8
Akt1s1
AKT1 substrate 1 (proline-rich)
chr8_-_45975224 0.319 ENSMUST00000095323.1
ENSMUST00000098786.2
1700029J07Rik

RIKEN cDNA 1700029J07 gene

chr10_-_57532489 0.301 ENSMUST00000020027.4
Serinc1
serine incorporator 1
chr16_-_91728599 0.298 ENSMUST00000122254.1
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr3_-_116614587 0.284 ENSMUST00000041524.4
Trmt13
tRNA methyltransferase 13
chr15_+_84232030 0.283 ENSMUST00000023072.6
Parvb
parvin, beta
chr8_+_105701142 0.277 ENSMUST00000098444.2
Pard6a
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr6_+_57702601 0.276 ENSMUST00000072954.1
ENSMUST00000050077.8
Lancl2

LanC (bacterial lantibiotic synthetase component C)-like 2

chr1_-_180996145 0.271 ENSMUST00000154133.1
Ephx1
epoxide hydrolase 1, microsomal
chr14_+_120275669 0.257 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr7_-_119720742 0.253 ENSMUST00000033236.7
Thumpd1
THUMP domain containing 1
chr10_-_57532416 0.252 ENSMUST00000169122.1
Serinc1
serine incorporator 1
chr19_-_6942406 0.242 ENSMUST00000099782.3
Gpr137
G protein-coupled receptor 137
chr2_-_33087169 0.236 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr7_+_97720839 0.235 ENSMUST00000070021.1
Gm9990
predicted gene 9990
chr6_+_11925869 0.226 ENSMUST00000115510.1
ENSMUST00000115511.2
ENSMUST00000090632.4
Phf14


PHD finger protein 14


chr4_+_130913264 0.223 ENSMUST00000156225.1
ENSMUST00000156742.1
Laptm5

lysosomal-associated protein transmembrane 5

chr4_+_130913120 0.217 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr11_-_70239794 0.208 ENSMUST00000040428.3
Rnasek
ribonuclease, RNase K
chr7_+_44849581 0.207 ENSMUST00000150335.1
ENSMUST00000107882.1
Akt1s1

AKT1 substrate 1 (proline-rich)

chr7_+_44849949 0.201 ENSMUST00000141311.1
ENSMUST00000107880.1
Akt1s1

AKT1 substrate 1 (proline-rich)

chr5_-_112589990 0.193 ENSMUST00000183186.1
ENSMUST00000182949.1
1700034G24Rik

RIKEN cDNA 1700034G24 gene

chr16_+_24721842 0.191 ENSMUST00000115314.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr2_+_172248492 0.187 ENSMUST00000038532.1
Mc3r
melanocortin 3 receptor
chr16_+_4886100 0.183 ENSMUST00000070658.8
ENSMUST00000023159.8
Mgrn1

mahogunin, ring finger 1

chr19_+_54045182 0.181 ENSMUST00000036700.5
Adra2a
adrenergic receptor, alpha 2a
chr12_+_84114321 0.181 ENSMUST00000123491.1
ENSMUST00000046340.2
ENSMUST00000136159.1
Dnal1


dynein, axonemal, light chain 1


chr6_+_90369486 0.178 ENSMUST00000113539.1
ENSMUST00000075117.3
ENSMUST00000045740.6
Zxdc


ZXD family zinc finger C


chr6_+_57703051 0.177 ENSMUST00000151042.1
Lancl2
LanC (bacterial lantibiotic synthetase component C)-like 2
chr8_-_22653406 0.175 ENSMUST00000033938.5
Polb
polymerase (DNA directed), beta
chr1_-_179546261 0.171 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr19_+_18631927 0.168 ENSMUST00000159572.1
ENSMUST00000042392.7
Nmrk1

nicotinamide riboside kinase 1

chr2_+_153741274 0.166 ENSMUST00000028981.8
Mapre1
microtubule-associated protein, RP/EB family, member 1
chr16_+_17070281 0.165 ENSMUST00000090199.3
Ypel1
yippee-like 1 (Drosophila)
chr2_-_177925604 0.165 ENSMUST00000108934.2
ENSMUST00000081529.4
C330013J21Rik

RIKEN cDNA C330013J21 gene

chr1_-_125913101 0.159 ENSMUST00000161361.1
Lypd1
Ly6/Plaur domain containing 1
chr11_+_75588064 0.158 ENSMUST00000143219.1
ENSMUST00000179521.1
ENSMUST00000179445.1
Pitpna


phosphatidylinositol transfer protein, alpha


chr9_-_104262900 0.153 ENSMUST00000035170.6
Dnajc13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr8_+_45975514 0.144 ENSMUST00000034051.6
Ufsp2
UFM1-specific peptidase 2
chr12_-_108702265 0.143 ENSMUST00000167978.1
ENSMUST00000021691.4
Degs2

degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase

chr5_+_105876532 0.143 ENSMUST00000150440.1
ENSMUST00000031227.4
Zfp326

zinc finger protein 326

chr15_-_89429851 0.139 ENSMUST00000023289.6
Chkb
choline kinase beta
chr6_-_89595647 0.137 ENSMUST00000032172.8
ENSMUST00000113550.3
Chchd6

coiled-coil-helix-coiled-coil-helix domain containing 6

chr15_+_89429560 0.136 ENSMUST00000168646.1
C730034F03Rik
RIKEN cDNA C730034F03 gene
chr1_+_171270321 0.135 ENSMUST00000064272.3
ENSMUST00000141999.1
ENSMUST00000111313.3
B4galt3


UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3


chr15_+_85510812 0.133 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr9_-_63377835 0.133 ENSMUST00000034920.9
Map2k5
mitogen-activated protein kinase kinase 5
chr8_+_25720054 0.129 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr7_+_96951505 0.127 ENSMUST00000044466.5
Nars2
asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)
chr7_+_45526330 0.126 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr12_+_70974621 0.121 ENSMUST00000160027.1
ENSMUST00000160864.1
Psma3

proteasome (prosome, macropain) subunit, alpha type 3

chr16_-_32868325 0.119 ENSMUST00000089684.3
ENSMUST00000040986.8
ENSMUST00000115105.2
1700021K19Rik


RIKEN cDNA 1700021K19 gene


chr10_+_78425670 0.117 ENSMUST00000005185.6
Cstb
cystatin B
chr9_-_35267746 0.117 ENSMUST00000125087.1
ENSMUST00000121564.1
ENSMUST00000063782.5
ENSMUST00000059057.7
Fam118b



family with sequence similarity 118, member B



chr12_-_70231414 0.116 ENSMUST00000161083.1
Pygl
liver glycogen phosphorylase
chr17_-_32822200 0.108 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr15_-_27681498 0.107 ENSMUST00000100739.3
Fam105a
family with sequence similarity 105, member A
chr14_-_70599832 0.102 ENSMUST00000022690.9
Fam160b2
family with sequence similarity 160, member B2
chr8_-_3621270 0.100 ENSMUST00000159548.1
ENSMUST00000019614.6
Xab2

XPA binding protein 2

chr11_-_102556122 0.099 ENSMUST00000143842.1
Gpatch8
G patch domain containing 8
chr10_-_39899238 0.099 ENSMUST00000178563.1
AA474331
expressed sequence AA474331
chr5_-_113650390 0.095 ENSMUST00000047936.6
Cmklr1
chemokine-like receptor 1
chr1_+_44119952 0.094 ENSMUST00000114709.2
Bivm
basic, immunoglobulin-like variable motif containing
chr16_+_91391721 0.094 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr11_+_72301613 0.082 ENSMUST00000151440.1
ENSMUST00000146233.1
ENSMUST00000140842.2
Xaf1


XIAP associated factor 1


chr6_+_87887814 0.080 ENSMUST00000113607.3
ENSMUST00000049966.5
Copg1

coatomer protein complex, subunit gamma 1

chr8_+_70131327 0.079 ENSMUST00000095273.5
Nr2c2ap
nuclear receptor 2C2-associated protein
chr15_+_78935177 0.075 ENSMUST00000145157.1
ENSMUST00000123013.1
Nol12

nucleolar protein 12

chr15_+_35371498 0.069 ENSMUST00000048646.7
Vps13b
vacuolar protein sorting 13B (yeast)
chr2_-_175175871 0.067 ENSMUST00000109054.2
Gm14443
predicted gene 14443
chr10_-_26373956 0.061 ENSMUST00000105519.3
ENSMUST00000040219.6
L3mbtl3

l(3)mbt-like 3 (Drosophila)

chr14_-_123627059 0.057 ENSMUST00000000201.5
Nalcn
sodium leak channel, non-selective
chr6_-_86733268 0.054 ENSMUST00000001185.7
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr4_-_116555896 0.053 ENSMUST00000069674.5
ENSMUST00000106478.2
Tmem69

transmembrane protein 69

chr6_-_86733218 0.050 ENSMUST00000113679.1
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr16_-_20425881 0.046 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr13_+_4191163 0.046 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chr11_-_98149551 0.045 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr9_-_48495321 0.045 ENSMUST00000170000.2
Rbm7
RNA binding motif protein 7
chr9_-_54193442 0.044 ENSMUST00000034811.7
Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
chr2_+_180071793 0.044 ENSMUST00000108901.1
Mtg2
mitochondrial ribosome associated GTPase 2
chr6_-_87851011 0.038 ENSMUST00000113617.1
Cnbp
cellular nucleic acid binding protein
chr9_-_55283582 0.032 ENSMUST00000114306.1
ENSMUST00000164721.1
Nrg4

neuregulin 4

chr7_+_96951552 0.031 ENSMUST00000107159.1
Nars2
asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)
chr18_-_70141568 0.029 ENSMUST00000121693.1
Rab27b
RAB27b, member RAS oncogene family
chr1_-_74601345 0.029 ENSMUST00000136078.1
ENSMUST00000132081.1
ENSMUST00000113721.1
ENSMUST00000027357.5
Rnf25



ring finger protein 25



chr2_+_35622160 0.023 ENSMUST00000112992.2
Dab2ip
disabled 2 interacting protein
chr9_+_48495345 0.010 ENSMUST00000048824.7
Gm5617
predicted gene 5617
chr19_-_14598031 0.009 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_-_14597983 0.008 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr9_-_7184440 0.001 ENSMUST00000140466.1
Dync2h1
dynein cytoplasmic 2 heavy chain 1
chr4_-_138913915 0.000 ENSMUST00000097830.3
Otud3
OTU domain containing 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.5 2.0 GO:0061623 glycolytic process from galactose(GO:0061623)
0.2 1.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.5 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.2 0.5 GO:0006550 isoleucine catabolic process(GO:0006550) acetyl-CoA catabolic process(GO:0046356) ketone body catabolic process(GO:0046952)
0.2 0.5 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 1.6 GO:0060347 heart trabecula formation(GO:0060347)
0.1 1.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 1.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 1.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.3 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.5 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 1.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.6 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.4 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 1.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.2 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.5 GO:0006560 proline metabolic process(GO:0006560)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.2 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) thermoception(GO:0050955)
0.0 0.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0070375 ERK5 cascade(GO:0070375)
0.0 0.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.4 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.3 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.7 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 1.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.5 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 1.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.3 GO:0034312 diol biosynthetic process(GO:0034312)
0.0 0.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.0 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 1.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.4 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.9 GO:0048477 oogenesis(GO:0048477)
0.0 0.4 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 1.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.5 GO:0097447 dendritic tree(GO:0097447)
0.1 0.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 2.8 GO:0031430 M band(GO:0031430)
0.1 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 1.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 1.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.5 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.2 1.2 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.0 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.5 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.2 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.1 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.5 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 2.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.6 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.4 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.4 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.7 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID_INSULIN_PATHWAY Insulin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 1.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 2.2 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.6 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.7 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 3.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.6 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 2.5 REACTOME_METABOLISM_OF_CARBOHYDRATES Genes involved in Metabolism of carbohydrates