Motif ID: Pax3

Z-value: 0.696


Transcription factors associated with Pax3:

Gene SymbolEntrez IDGene Name
Pax3 ENSMUSG00000004872.9 Pax3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax3mm10_v2_chr1_-_78196832_781968450.634.7e-03Click!


Activity profile for motif Pax3.

activity profile for motif Pax3


Sorted Z-values histogram for motif Pax3

Sorted Z-values for motif Pax3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax3

PNG image of the network

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Top targets:


Showing 1 to 20 of 38 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_40346290 2.123 ENSMUST00000121357.1
 Gramd1b
GRAM domain containing 1B
chr10_+_82138253 1.978 ENSMUST00000105314.2
 AU041133
expressed sequence AU041133
chr4_+_127077374 1.687 ENSMUST00000046751.6
ENSMUST00000094713.3
 Zmym6

zinc finger, MYM-type 6

chr14_+_51893610 1.598 ENSMUST00000047726.5
ENSMUST00000161888.1
 Slc39a2

solute carrier family 39 (zinc transporter), member 2

chrX_-_103623648 1.352 ENSMUST00000156211.1
 Ftx
Ftx transcript, Xist regulator (non-protein coding)
chr2_-_136387929 1.179 ENSMUST00000035264.2
ENSMUST00000077200.3
 Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr12_+_38780284 1.093 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr7_+_120843551 1.085 ENSMUST00000106489.1
ENSMUST00000143279.1
 Eef2k

eukaryotic elongation factor-2 kinase

chrX_+_159840463 1.075 ENSMUST00000112451.1
ENSMUST00000112453.2
 Sh3kbp1

SH3-domain kinase binding protein 1

chr12_+_38781093 1.001 ENSMUST00000161513.1
 Etv1
ets variant gene 1
chr12_+_38780817 0.965 ENSMUST00000160856.1
 Etv1
ets variant gene 1
chr12_+_109540979 0.918 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
 Meg3


maternally expressed 3


chrX_-_103623704 0.914 ENSMUST00000130063.1
ENSMUST00000125419.1
 Ftx

Ftx transcript, Xist regulator (non-protein coding)

chr8_+_71887264 0.880 ENSMUST00000034259.7
 Zfp709
zinc finger protein 709
chr7_+_30121915 0.833 ENSMUST00000098596.3
ENSMUST00000153792.1
 Zfp382

zinc finger protein 382

chr12_+_52699297 0.781 ENSMUST00000095737.3
 Akap6
A kinase (PRKA) anchor protein 6
chr3_+_36159522 0.766 ENSMUST00000165956.2
 D3Ertd254e
DNA segment, Chr 3, ERATO Doi 254, expressed
chr16_-_32877723 0.655 ENSMUST00000119810.1
 1700021K19Rik
RIKEN cDNA 1700021K19 gene
chr1_+_176814660 0.638 ENSMUST00000056773.8
ENSMUST00000027785.8
 Sdccag8

serologically defined colon cancer antigen 8

chr18_+_35562158 0.637 ENSMUST00000166793.1
 Matr3
matrin 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.5 2.3 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 1.6 GO:0006829 zinc II ion transport(GO:0006829)
0.0 1.1 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.9 GO:0034605 cellular response to heat(GO:0034605)
0.2 0.8 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 0.6 GO:0018307 tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307)
0.1 0.5 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)

Gene overrepresentation in cellular_component category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)

Gene overrepresentation in molecular_function category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.4 1.1 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.1 0.6 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.1 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.1 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.1 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 1.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.1 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors