Motif ID: Pax5
Z-value: 1.382
Transcription factors associated with Pax5:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pax5 | ENSMUSG00000014030.9 | Pax5 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pax5 | mm10_v2_chr4_-_44710408_44710418 | -0.41 | 9.3e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 5.1 | GO:0007521 | muscle cell fate determination(GO:0007521) |
1.1 | 6.7 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
1.0 | 4.0 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
0.9 | 3.6 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.9 | 3.5 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
0.8 | 1.5 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
0.7 | 2.9 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
0.7 | 2.1 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
0.6 | 1.8 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
0.6 | 1.7 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) |
0.6 | 1.7 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
0.6 | 1.7 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.6 | 7.3 | GO:0070842 | aggresome assembly(GO:0070842) |
0.5 | 1.6 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
0.5 | 2.7 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
0.5 | 2.0 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
0.5 | 1.5 | GO:1900738 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
0.5 | 0.5 | GO:0001941 | postsynaptic membrane organization(GO:0001941) |
0.5 | 1.5 | GO:0010751 | regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763) |
0.5 | 2.0 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
0.5 | 1.4 | GO:0060060 | post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
0.4 | 2.2 | GO:0042891 | antibiotic transport(GO:0042891) |
0.4 | 1.6 | GO:0014042 | positive regulation of neuron maturation(GO:0014042) |
0.4 | 1.2 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.4 | 1.2 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.4 | 2.0 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.4 | 1.5 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
0.4 | 2.5 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
0.4 | 1.8 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.4 | 3.6 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.4 | 2.8 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
0.3 | 1.4 | GO:0043974 | histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) |
0.3 | 1.7 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
0.3 | 1.0 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
0.3 | 1.0 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
0.3 | 1.3 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
0.3 | 1.3 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.3 | 1.5 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
0.3 | 0.6 | GO:0060596 | mammary placode formation(GO:0060596) |
0.3 | 0.3 | GO:0021593 | rhombomere morphogenesis(GO:0021593) |
0.3 | 1.2 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
0.3 | 5.1 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.3 | 2.1 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.3 | 0.9 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
0.3 | 1.5 | GO:0007262 | STAT protein import into nucleus(GO:0007262) |
0.3 | 1.7 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.3 | 2.5 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
0.3 | 1.1 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.3 | 0.8 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
0.3 | 1.3 | GO:0019236 | response to pheromone(GO:0019236) |
0.3 | 1.1 | GO:0099527 | postsynapse to nucleus signaling pathway(GO:0099527) |
0.3 | 2.1 | GO:0042756 | drinking behavior(GO:0042756) |
0.3 | 1.8 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
0.3 | 3.0 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.3 | 3.3 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
0.2 | 1.2 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
0.2 | 1.2 | GO:0097167 | circadian regulation of translation(GO:0097167) |
0.2 | 0.9 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
0.2 | 0.7 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
0.2 | 0.5 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
0.2 | 0.7 | GO:0071579 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579) |
0.2 | 3.3 | GO:0046548 | retinal rod cell development(GO:0046548) |
0.2 | 2.3 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
0.2 | 0.9 | GO:0086048 | membrane depolarization during bundle of His cell action potential(GO:0086048) |
0.2 | 0.7 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
0.2 | 2.2 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.2 | 3.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.2 | 0.7 | GO:0090425 | hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
0.2 | 1.1 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
0.2 | 2.8 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.2 | 0.6 | GO:0050975 | sensory perception of touch(GO:0050975) |
0.2 | 0.2 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
0.2 | 0.6 | GO:1904192 | cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193) |
0.2 | 1.4 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.2 | 0.8 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
0.2 | 3.2 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.2 | 0.6 | GO:0046549 | retinal cone cell development(GO:0046549) |
0.2 | 0.6 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.2 | 0.6 | GO:0039533 | regulation of MDA-5 signaling pathway(GO:0039533) |
0.2 | 5.7 | GO:0007616 | long-term memory(GO:0007616) |
0.2 | 0.6 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
0.2 | 0.4 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
0.2 | 0.5 | GO:0006553 | lysine metabolic process(GO:0006553) |
0.2 | 1.4 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.2 | 0.9 | GO:0097343 | ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026) |
0.2 | 0.8 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
0.2 | 1.0 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
0.2 | 1.5 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.2 | 1.0 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
0.2 | 1.8 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
0.2 | 2.5 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
0.2 | 1.3 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.2 | 3.1 | GO:0030033 | microvillus assembly(GO:0030033) |
0.2 | 0.8 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.2 | 0.8 | GO:0006868 | glutamine transport(GO:0006868) cellular response to potassium ion starvation(GO:0051365) |
0.2 | 0.8 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
0.2 | 2.1 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.2 | 0.8 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
0.2 | 0.9 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.2 | 0.8 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
0.2 | 1.2 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
0.2 | 0.5 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
0.1 | 0.1 | GO:0042713 | sperm ejaculation(GO:0042713) |
0.1 | 1.6 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
0.1 | 0.4 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
0.1 | 0.7 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
0.1 | 0.8 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
0.1 | 1.4 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
0.1 | 0.5 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
0.1 | 0.4 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
0.1 | 0.5 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
0.1 | 0.6 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
0.1 | 1.3 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
0.1 | 0.9 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.1 | 1.6 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.1 | 0.6 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.1 | 0.4 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) |
0.1 | 0.5 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
0.1 | 0.4 | GO:0032916 | positive regulation of transforming growth factor beta3 production(GO:0032916) |
0.1 | 0.5 | GO:1904953 | Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953) |
0.1 | 0.5 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
0.1 | 1.4 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.1 | 1.5 | GO:0033005 | positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
0.1 | 0.3 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.1 | 2.9 | GO:0061157 | mRNA destabilization(GO:0061157) |
0.1 | 8.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.1 | 2.5 | GO:0032757 | positive regulation of interleukin-8 production(GO:0032757) |
0.1 | 0.6 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.1 | 0.6 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
0.1 | 0.2 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
0.1 | 0.5 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
0.1 | 1.1 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
0.1 | 0.9 | GO:0071569 | protein ufmylation(GO:0071569) |
0.1 | 0.5 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
0.1 | 0.9 | GO:0043084 | penile erection(GO:0043084) |
0.1 | 2.8 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.1 | 0.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.1 | 1.3 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
0.1 | 0.7 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.1 | 0.3 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
0.1 | 0.7 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
0.1 | 0.2 | GO:1904468 | negative regulation of tumor necrosis factor secretion(GO:1904468) |
0.1 | 2.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.1 | 0.6 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
0.1 | 0.3 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
0.1 | 1.3 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
0.1 | 0.5 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) post-embryonic camera-type eye morphogenesis(GO:0048597) |
0.1 | 0.3 | GO:0070973 | COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973) |
0.1 | 1.2 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
0.1 | 0.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 1.6 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
0.1 | 1.5 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.1 | 0.4 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
0.1 | 0.8 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.1 | 0.9 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
0.1 | 1.7 | GO:0021860 | pyramidal neuron development(GO:0021860) |
0.1 | 0.5 | GO:0015879 | carnitine transport(GO:0015879) |
0.1 | 0.7 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
0.1 | 0.2 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
0.1 | 0.7 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
0.1 | 0.5 | GO:0048702 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) embryonic neurocranium morphogenesis(GO:0048702) |
0.1 | 0.3 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.1 | 0.6 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.1 | 0.2 | GO:2001223 | negative regulation of neuron migration(GO:2001223) |
0.1 | 0.4 | GO:1904177 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) regulation of adipose tissue development(GO:1904177) |
0.1 | 1.8 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
0.1 | 0.4 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
0.1 | 1.3 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
0.1 | 0.4 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
0.1 | 0.2 | GO:0097051 | establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) |
0.1 | 3.6 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.1 | 1.0 | GO:0009072 | aromatic amino acid family metabolic process(GO:0009072) |
0.1 | 0.2 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.1 | 0.6 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
0.1 | 0.5 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.1 | 1.4 | GO:0090218 | positive regulation of lipid kinase activity(GO:0090218) |
0.1 | 0.2 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
0.1 | 0.1 | GO:0021546 | rhombomere development(GO:0021546) |
0.1 | 0.8 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
0.1 | 2.5 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 1.0 | GO:0045332 | phospholipid translocation(GO:0045332) |
0.1 | 0.8 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.1 | 0.2 | GO:0097278 | complement-dependent cytotoxicity(GO:0097278) |
0.1 | 0.3 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572) |
0.1 | 0.5 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.1 | 0.7 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
0.1 | 0.6 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
0.1 | 0.3 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
0.1 | 0.5 | GO:0070447 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) |
0.1 | 0.2 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
0.1 | 0.4 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
0.1 | 0.3 | GO:0009098 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
0.1 | 0.5 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
0.1 | 0.1 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
0.1 | 1.3 | GO:0032288 | myelin assembly(GO:0032288) |
0.1 | 0.3 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.1 | 0.4 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
0.1 | 0.2 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
0.1 | 1.1 | GO:0010803 | regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803) |
0.1 | 0.4 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
0.1 | 5.9 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
0.1 | 1.1 | GO:0071800 | podosome assembly(GO:0071800) |
0.1 | 0.9 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.1 | 1.3 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.1 | 0.8 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
0.1 | 0.9 | GO:0030204 | chondroitin sulfate metabolic process(GO:0030204) |
0.1 | 2.9 | GO:0034605 | cellular response to heat(GO:0034605) |
0.1 | 0.2 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
0.1 | 3.3 | GO:0015807 | L-amino acid transport(GO:0015807) |
0.1 | 0.8 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.1 | 0.9 | GO:0048240 | sperm capacitation(GO:0048240) |
0.1 | 1.6 | GO:0010812 | negative regulation of cell-substrate adhesion(GO:0010812) |
0.1 | 1.7 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.1 | 0.5 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
0.1 | 0.4 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.1 | 1.0 | GO:0044804 | nucleophagy(GO:0044804) |
0.1 | 1.4 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.1 | 1.1 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.1 | 0.7 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
0.1 | 0.2 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.1 | 0.6 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.2 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.0 | 1.2 | GO:0001523 | retinoid metabolic process(GO:0001523) |
0.0 | 0.5 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
0.0 | 0.2 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
0.0 | 1.2 | GO:0071625 | vocalization behavior(GO:0071625) |
0.0 | 2.3 | GO:0048278 | vesicle docking(GO:0048278) |
0.0 | 0.3 | GO:0019348 | dolichol metabolic process(GO:0019348) |
0.0 | 0.1 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
0.0 | 0.2 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
0.0 | 0.1 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.0 | 0.9 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.0 | 0.7 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
0.0 | 1.0 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
0.0 | 0.5 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
0.0 | 0.3 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.0 | 1.2 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.8 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
0.0 | 0.9 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 1.5 | GO:0043113 | receptor clustering(GO:0043113) |
0.0 | 0.0 | GO:0002030 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) |
0.0 | 0.8 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
0.0 | 0.5 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
0.0 | 0.3 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
0.0 | 0.2 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.0 | 0.1 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
0.0 | 0.2 | GO:0019530 | taurine metabolic process(GO:0019530) |
0.0 | 0.2 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
0.0 | 2.7 | GO:0007338 | single fertilization(GO:0007338) |
0.0 | 3.2 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
0.0 | 0.2 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
0.0 | 0.4 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 0.3 | GO:0042428 | serotonin metabolic process(GO:0042428) |
0.0 | 0.2 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
0.0 | 4.3 | GO:0051017 | actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572) |
0.0 | 0.6 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
0.0 | 0.6 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
0.0 | 0.2 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.0 | 0.7 | GO:0021681 | cerebellar granular layer development(GO:0021681) |
0.0 | 0.2 | GO:0098543 | detection of bacterium(GO:0016045) detection of other organism(GO:0098543) |
0.0 | 1.7 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
0.0 | 0.1 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
0.0 | 0.9 | GO:0031297 | replication fork processing(GO:0031297) |
0.0 | 0.2 | GO:0051176 | positive regulation of sulfur metabolic process(GO:0051176) |
0.0 | 0.3 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.0 | 0.2 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
0.0 | 0.5 | GO:0030575 | nuclear body organization(GO:0030575) |
0.0 | 0.1 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
0.0 | 0.6 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
0.0 | 0.6 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
0.0 | 0.3 | GO:0033572 | transferrin transport(GO:0033572) |
0.0 | 0.4 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
0.0 | 0.5 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.0 | 0.4 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 1.1 | GO:0045453 | bone resorption(GO:0045453) |
0.0 | 0.6 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
0.0 | 0.0 | GO:2000642 | negative regulation of vacuolar transport(GO:1903336) negative regulation of early endosome to late endosome transport(GO:2000642) |
0.0 | 0.1 | GO:0060027 | convergent extension involved in gastrulation(GO:0060027) |
0.0 | 0.9 | GO:0016079 | synaptic vesicle exocytosis(GO:0016079) |
0.0 | 0.3 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.0 | 1.0 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
0.0 | 0.2 | GO:0007413 | axonal fasciculation(GO:0007413) |
0.0 | 0.3 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
0.0 | 0.4 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
0.0 | 0.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.0 | 0.8 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 0.5 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
0.0 | 0.4 | GO:0070296 | sarcoplasmic reticulum calcium ion transport(GO:0070296) |
0.0 | 0.3 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
0.0 | 0.2 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
0.0 | 0.4 | GO:0097484 | dendrite extension(GO:0097484) |
0.0 | 0.6 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 2.7 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
0.0 | 0.1 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
0.0 | 0.7 | GO:0007032 | endosome organization(GO:0007032) |
0.0 | 0.4 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.0 | 0.4 | GO:0045815 | positive regulation of gene expression, epigenetic(GO:0045815) |
0.0 | 0.2 | GO:0061577 | calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) |
0.0 | 0.7 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
0.0 | 0.0 | GO:0030862 | regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862) |
0.0 | 0.2 | GO:0014029 | neural crest formation(GO:0014029) |
0.0 | 0.4 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.0 | 0.1 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.0 | 0.1 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
0.0 | 0.1 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
0.0 | 0.2 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.4 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.3 | GO:0010830 | regulation of myotube differentiation(GO:0010830) |
0.0 | 0.3 | GO:0045475 | locomotor rhythm(GO:0045475) |
0.0 | 0.3 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
0.0 | 0.2 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.4 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.0 | 0.4 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
0.0 | 0.3 | GO:0048041 | cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) |
0.0 | 0.4 | GO:0044458 | motile cilium assembly(GO:0044458) |
0.0 | 0.1 | GO:0033578 | protein glycosylation in Golgi(GO:0033578) GDP-L-fucose metabolic process(GO:0046368) |
0.0 | 1.0 | GO:0017157 | regulation of exocytosis(GO:0017157) |
0.0 | 0.1 | GO:0015862 | uridine transport(GO:0015862) |
0.0 | 0.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
0.0 | 0.1 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
0.0 | 0.9 | GO:0040014 | regulation of multicellular organism growth(GO:0040014) |
0.0 | 1.7 | GO:0008360 | regulation of cell shape(GO:0008360) |
0.0 | 0.2 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
0.0 | 0.4 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
0.0 | 0.2 | GO:0051297 | microtubule organizing center organization(GO:0031023) centrosome organization(GO:0051297) |
0.0 | 0.3 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
0.0 | 1.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.0 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
0.0 | 0.1 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
0.0 | 0.1 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
0.0 | 0.1 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.0 | 0.1 | GO:0045026 | plasma membrane fusion(GO:0045026) |
0.0 | 0.0 | GO:0003310 | pancreatic A cell differentiation(GO:0003310) |
0.0 | 0.1 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.0 | 0.3 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.0 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
0.0 | 0.1 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
0.0 | 0.2 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.4 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.8 | 12.5 | GO:0005614 | interstitial matrix(GO:0005614) |
0.7 | 2.0 | GO:0072534 | perineuronal net(GO:0072534) |
0.5 | 2.8 | GO:0044308 | axonal spine(GO:0044308) |
0.4 | 1.3 | GO:0098831 | presynaptic active zone cytoplasmic component(GO:0098831) |
0.4 | 1.7 | GO:0097441 | basilar dendrite(GO:0097441) |
0.4 | 1.6 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
0.4 | 3.0 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.3 | 1.2 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
0.3 | 1.1 | GO:0031673 | H zone(GO:0031673) |
0.3 | 0.9 | GO:0036128 | CatSper complex(GO:0036128) |
0.3 | 4.2 | GO:0043083 | synaptic cleft(GO:0043083) |
0.3 | 1.1 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
0.3 | 1.6 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.2 | 4.8 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.2 | 1.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.2 | 1.1 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.2 | 0.6 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
0.2 | 0.6 | GO:0016939 | kinesin II complex(GO:0016939) |
0.2 | 0.5 | GO:0098835 | presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
0.2 | 1.0 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.2 | 2.6 | GO:1990635 | proximal dendrite(GO:1990635) |
0.2 | 2.0 | GO:0016600 | flotillin complex(GO:0016600) |
0.2 | 1.3 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
0.2 | 1.9 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.2 | 0.3 | GO:0097513 | myosin II filament(GO:0097513) |
0.1 | 2.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.1 | 0.3 | GO:0008091 | spectrin(GO:0008091) |
0.1 | 1.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.1 | 1.3 | GO:0098839 | postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634) |
0.1 | 0.9 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.1 | 3.5 | GO:0033268 | node of Ranvier(GO:0033268) |
0.1 | 0.5 | GO:0031084 | BLOC-2 complex(GO:0031084) |
0.1 | 1.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.1 | 0.6 | GO:0031523 | Myb complex(GO:0031523) |
0.1 | 3.3 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.1 | 1.0 | GO:0097427 | microtubule bundle(GO:0097427) |
0.1 | 2.3 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.1 | 1.1 | GO:0045180 | basal cortex(GO:0045180) |
0.1 | 7.7 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.1 | 3.1 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.1 | 0.8 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
0.1 | 1.5 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.1 | 2.7 | GO:0030673 | axolemma(GO:0030673) |
0.1 | 1.9 | GO:0000145 | exocyst(GO:0000145) |
0.1 | 3.6 | GO:0031672 | A band(GO:0031672) |
0.1 | 0.2 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
0.1 | 0.6 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.1 | 0.3 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
0.1 | 0.3 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.1 | 4.0 | GO:0005871 | kinesin complex(GO:0005871) |
0.1 | 20.9 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.1 | 1.5 | GO:0097228 | sperm principal piece(GO:0097228) |
0.1 | 0.9 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.1 | 3.4 | GO:0002102 | podosome(GO:0002102) |
0.1 | 0.4 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.1 | 0.3 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.1 | 0.7 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.1 | 0.3 | GO:0001651 | dense fibrillar component(GO:0001651) |
0.1 | 1.4 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.1 | 1.1 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.1 | 0.9 | GO:0097542 | ciliary tip(GO:0097542) |
0.1 | 0.6 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 1.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.1 | 0.3 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.1 | 0.5 | GO:0097433 | dense body(GO:0097433) |
0.1 | 0.1 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.1 | 0.3 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.1 | 0.9 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.1 | 1.0 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.1 | 0.4 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.1 | 0.8 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.1 | 1.5 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.1 | 0.1 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
0.1 | 0.2 | GO:0042629 | mast cell granule(GO:0042629) |
0.1 | 0.4 | GO:0005638 | lamin filament(GO:0005638) |
0.1 | 0.2 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.1 | 1.3 | GO:0032589 | neuron projection membrane(GO:0032589) |
0.1 | 0.6 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 0.7 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.1 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
0.0 | 3.6 | GO:0043197 | dendritic spine(GO:0043197) neuron spine(GO:0044309) |
0.0 | 0.1 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.0 | 1.6 | GO:0005901 | caveola(GO:0005901) |
0.0 | 0.3 | GO:0001739 | sex chromatin(GO:0001739) |
0.0 | 9.2 | GO:0060076 | excitatory synapse(GO:0060076) |
0.0 | 0.3 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.0 | 0.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 1.1 | GO:0071565 | nBAF complex(GO:0071565) |
0.0 | 1.1 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.2 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.0 | 0.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.5 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
0.0 | 1.4 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
0.0 | 0.7 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.1 | GO:0044194 | cytolytic granule(GO:0044194) |
0.0 | 1.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.5 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 0.3 | GO:0000439 | core TFIIH complex(GO:0000439) |
0.0 | 0.6 | GO:0043218 | compact myelin(GO:0043218) |
0.0 | 0.9 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
0.0 | 0.6 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
0.0 | 0.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 1.6 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 3.6 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 0.5 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 0.2 | GO:0071439 | clathrin complex(GO:0071439) |
0.0 | 0.2 | GO:0002080 | acrosomal membrane(GO:0002080) |
0.0 | 0.2 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.0 | 0.3 | GO:0031931 | TORC1 complex(GO:0031931) |
0.0 | 2.6 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 0.1 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
0.0 | 0.9 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
0.0 | 0.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 2.8 | GO:0030016 | myofibril(GO:0030016) |
0.0 | 0.6 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 2.1 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 0.3 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.3 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.0 | 0.3 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
0.0 | 0.4 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.4 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.3 | GO:0032994 | protein-lipid complex(GO:0032994) |
0.0 | 14.1 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.0 | 2.4 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.0 | 0.1 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 0.2 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.0 | 0.2 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
0.0 | 0.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.1 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
0.0 | 0.4 | GO:0045177 | apical part of cell(GO:0045177) |
0.0 | 0.2 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 0.6 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 0.8 | GO:0016324 | apical plasma membrane(GO:0016324) |
0.0 | 0.7 | GO:0030027 | lamellipodium(GO:0030027) |
0.0 | 1.1 | GO:0005770 | late endosome(GO:0005770) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 4.8 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
1.0 | 2.9 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
0.8 | 6.3 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
0.7 | 2.0 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.6 | 3.9 | GO:0045545 | syndecan binding(GO:0045545) |
0.5 | 1.6 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
0.5 | 2.0 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.5 | 2.9 | GO:0019841 | retinol binding(GO:0019841) |
0.5 | 3.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.4 | 1.7 | GO:0038025 | reelin receptor activity(GO:0038025) |
0.4 | 1.3 | GO:0038132 | neuregulin binding(GO:0038132) |
0.4 | 3.3 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.4 | 2.8 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.4 | 2.3 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.4 | 2.6 | GO:0019534 | toxin transporter activity(GO:0019534) |
0.4 | 6.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.3 | 1.0 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) |
0.3 | 1.0 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
0.3 | 8.6 | GO:0001968 | fibronectin binding(GO:0001968) |
0.3 | 1.9 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
0.3 | 3.7 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.3 | 0.9 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
0.3 | 4.6 | GO:0003680 | AT DNA binding(GO:0003680) |
0.3 | 2.0 | GO:0099609 | microtubule lateral binding(GO:0099609) |
0.3 | 0.8 | GO:0015182 | L-asparagine transmembrane transporter activity(GO:0015182) |
0.3 | 0.8 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
0.2 | 2.2 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.2 | 2.0 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.2 | 1.6 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
0.2 | 0.4 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.2 | 1.3 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.2 | 0.9 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.2 | 1.7 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
0.2 | 1.1 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.2 | 0.6 | GO:0016748 | succinyltransferase activity(GO:0016748) |
0.2 | 4.9 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.2 | 2.5 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.2 | 1.8 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
0.2 | 0.8 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.2 | 0.6 | GO:0051765 | inositol tetrakisphosphate kinase activity(GO:0051765) |
0.2 | 1.2 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.2 | 1.4 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.2 | 1.6 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.2 | 1.0 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.2 | 0.8 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
0.2 | 1.5 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.2 | 1.5 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
0.2 | 2.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.2 | 1.1 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.2 | 0.6 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.2 | 0.6 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.2 | 1.6 | GO:1990239 | steroid hormone binding(GO:1990239) |
0.2 | 2.0 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
0.2 | 1.5 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.2 | 2.9 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.2 | 0.5 | GO:0015226 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
0.2 | 0.8 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.2 | 0.8 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.2 | 0.6 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
0.2 | 0.6 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.2 | 2.7 | GO:0046625 | sphingolipid binding(GO:0046625) |
0.2 | 0.8 | GO:0070330 | aromatase activity(GO:0070330) |
0.1 | 0.6 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
0.1 | 1.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.1 | 1.1 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.1 | 0.7 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.1 | 0.8 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.1 | 1.7 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.1 | 0.4 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
0.1 | 1.8 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.1 | 0.4 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.1 | 0.4 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
0.1 | 0.6 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.1 | 1.8 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
0.1 | 0.5 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
0.1 | 0.9 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
0.1 | 2.6 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.1 | 0.4 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
0.1 | 2.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.1 | 3.2 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.1 | 1.1 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 0.4 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
0.1 | 0.4 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
0.1 | 0.8 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 0.5 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
0.1 | 0.9 | GO:0031005 | filamin binding(GO:0031005) |
0.1 | 0.4 | GO:0008169 | C-methyltransferase activity(GO:0008169) |
0.1 | 0.5 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.1 | 2.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 1.0 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 1.4 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
0.1 | 3.7 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.1 | 0.3 | GO:0001847 | opsonin receptor activity(GO:0001847) |
0.1 | 2.8 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.1 | 2.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.9 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.1 | 2.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.1 | 1.4 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.1 | 1.5 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.1 | 1.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.1 | 0.4 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
0.1 | 0.6 | GO:0043559 | insulin binding(GO:0043559) |
0.1 | 0.5 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.1 | 0.3 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.1 | 1.8 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.1 | 0.7 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.1 | 0.6 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.1 | 1.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 0.3 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
0.1 | 1.2 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
0.1 | 0.3 | GO:0031543 | peptidyl-proline dioxygenase activity(GO:0031543) |
0.1 | 0.8 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.1 | 2.1 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.1 | 0.5 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.1 | 3.0 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.1 | 0.6 | GO:0016151 | nickel cation binding(GO:0016151) |
0.1 | 0.2 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
0.1 | 0.7 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.1 | 0.7 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
0.1 | 1.0 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.1 | 1.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.1 | 1.3 | GO:0031489 | myosin V binding(GO:0031489) |
0.1 | 0.3 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.1 | 2.3 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.1 | 0.5 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.1 | 0.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.1 | 0.3 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
0.1 | 0.3 | GO:0015093 | iron ion transmembrane transporter activity(GO:0005381) ferrous iron transmembrane transporter activity(GO:0015093) |
0.1 | 0.7 | GO:0050693 | LBD domain binding(GO:0050693) |
0.1 | 1.6 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.1 | 3.5 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.1 | 0.2 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
0.1 | 1.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 0.2 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.1 | 0.4 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
0.1 | 0.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 0.1 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
0.0 | 0.3 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.0 | 0.3 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.0 | 0.9 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.2 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
0.0 | 0.7 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.0 | 1.3 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 1.0 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.5 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 3.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 1.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.5 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.0 | 0.2 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.0 | 2.9 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 4.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 0.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.1 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.0 | 0.1 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
0.0 | 1.5 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 1.2 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.0 | 0.7 | GO:0035250 | UDP-galactosyltransferase activity(GO:0035250) |
0.0 | 0.1 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
0.0 | 0.1 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
0.0 | 0.1 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.0 | 1.0 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.5 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
0.0 | 0.4 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.0 | 0.5 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.0 | 0.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.2 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
0.0 | 0.1 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.0 | 1.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 1.6 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
0.0 | 0.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 0.6 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.0 | 0.3 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.0 | 1.9 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.0 | 0.9 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
0.0 | 0.4 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.6 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 1.1 | GO:0008528 | G-protein coupled peptide receptor activity(GO:0008528) |
0.0 | 0.3 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
0.0 | 0.1 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
0.0 | 1.4 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
0.0 | 0.1 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.0 | 0.1 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.0 | 1.1 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 3.0 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 0.6 | GO:0004532 | exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896) |
0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 2.9 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.0 | 1.6 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.0 | 1.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.1 | GO:0001727 | lipid kinase activity(GO:0001727) |
0.0 | 0.2 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.1 | GO:0004064 | arylesterase activity(GO:0004064) |
0.0 | 0.2 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 0.4 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.2 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.0 | 4.7 | GO:0016887 | ATPase activity(GO:0016887) |
0.0 | 2.8 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.3 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.3 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 0.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.4 | GO:0097110 | scaffold protein binding(GO:0097110) |
0.0 | 0.5 | GO:1901505 | carbohydrate derivative transporter activity(GO:1901505) |
0.0 | 0.1 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.0 | 0.6 | GO:0019003 | GDP binding(GO:0019003) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 10.6 | PID_REELIN_PATHWAY | Reelin signaling pathway |
0.2 | 2.5 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.1 | 1.9 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.1 | 5.5 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.1 | 4.2 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.1 | 3.4 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.1 | 0.4 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.1 | 1.5 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.1 | 4.0 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.1 | 4.0 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
0.1 | 3.3 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.1 | 3.6 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
0.1 | 2.7 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.1 | 3.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.1 | 0.9 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.1 | 1.2 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.1 | 0.4 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.1 | 2.2 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.1 | 0.8 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.1 | 1.4 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
0.0 | 0.8 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.0 | 0.5 | PID_CONE_PATHWAY | Visual signal transduction: Cones |
0.0 | 1.0 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.0 | 1.3 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 1.5 | PID_RHOA_PATHWAY | RhoA signaling pathway |
0.0 | 0.9 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.5 | PID_S1P_S1P3_PATHWAY | S1P3 pathway |
0.0 | 0.9 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 1.0 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 0.5 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.9 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 0.9 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 1.2 | PID_BCR_5PATHWAY | BCR signaling pathway |
0.0 | 0.7 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
0.0 | 0.4 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.0 | 0.5 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
0.0 | 1.2 | PID_AVB3_INTEGRIN_PATHWAY | Integrins in angiogenesis |
0.0 | 0.6 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 0.3 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 0.7 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
0.0 | 0.5 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.0 | 0.7 | PID_ERBB1_DOWNSTREAM_PATHWAY | ErbB1 downstream signaling |
0.0 | 0.3 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
0.0 | 0.2 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
0.0 | 0.2 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 0.2 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.2 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.9 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.2 | 5.5 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
0.2 | 4.9 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.2 | 1.2 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.2 | 1.3 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
0.2 | 1.4 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
0.2 | 2.0 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
0.2 | 1.1 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.2 | 5.9 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.1 | 2.2 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.1 | 4.6 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.1 | 0.7 | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | Genes involved in Downstream signal transduction |
0.1 | 1.3 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.1 | 1.8 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.1 | 1.3 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.1 | 0.8 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.1 | 1.4 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | Genes involved in Platelet sensitization by LDL |
0.1 | 1.1 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.1 | 1.4 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.1 | 0.7 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.1 | 1.7 | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
0.1 | 5.9 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.1 | 0.6 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
0.1 | 2.9 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
0.1 | 1.4 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
0.1 | 2.2 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
0.1 | 2.6 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.1 | 0.4 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
0.1 | 0.4 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
0.1 | 2.6 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.1 | 1.9 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.1 | 0.8 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.1 | 1.0 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.1 | 0.9 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
0.1 | 6.0 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
0.1 | 0.8 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.1 | 2.2 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.1 | 2.4 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.1 | 1.1 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
0.1 | 0.9 | REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING | Genes involved in GRB2 events in ERBB2 signaling |
0.0 | 3.9 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 1.3 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
0.0 | 3.1 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 3.0 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.0 | 0.5 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.0 | 0.9 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
0.0 | 0.2 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.0 | 0.6 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.0 | 0.8 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 0.5 | REACTOME_IL_RECEPTOR_SHC_SIGNALING | Genes involved in Interleukin receptor SHC signaling |
0.0 | 0.8 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.0 | 0.5 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.0 | 1.5 | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | Genes involved in NCAM signaling for neurite out-growth |
0.0 | 0.9 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
0.0 | 0.6 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.0 | 0.2 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.0 | 0.6 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.0 | 0.5 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 0.6 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.0 | 0.4 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
0.0 | 0.3 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 0.2 | REACTOME_NOD1_2_SIGNALING_PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
0.0 | 0.4 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 1.1 | REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM | Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism |
0.0 | 0.6 | REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
0.0 | 0.4 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
0.0 | 0.3 | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | Genes involved in Double-Strand Break Repair |
0.0 | 0.3 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 0.2 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 0.3 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
0.0 | 0.5 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 0.5 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.2 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.0 | 0.2 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |