Motif ID: Pax5

Z-value: 1.382


Transcription factors associated with Pax5:

Gene SymbolEntrez IDGene Name
Pax5 ENSMUSG00000014030.9 Pax5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax5mm10_v2_chr4_-_44710408_44710418-0.419.3e-02Click!


Activity profile for motif Pax5.

activity profile for motif Pax5


Sorted Z-values histogram for motif Pax5

Sorted Z-values for motif Pax5



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_89520152 4.843 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr13_+_83573577 4.601 ENSMUST00000185052.1
Mef2c
myocyte enhancer factor 2C
chr16_+_45094036 4.352 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr16_+_45093611 4.235 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr10_-_110000219 4.005 ENSMUST00000032719.7
Nav3
neuron navigator 3
chr4_-_64046925 3.898 ENSMUST00000107377.3
Tnc
tenascin C
chr2_-_162661075 3.672 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt



protein tyrosine phosphatase, receptor type, T



chr10_+_127725392 3.644 ENSMUST00000026466.3
Tac2
tachykinin 2
chr4_-_123664725 3.577 ENSMUST00000147030.1
Macf1
microtubule-actin crosslinking factor 1
chr3_-_152982240 3.386 ENSMUST00000044278.5
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr6_-_18514802 3.326 ENSMUST00000090601.5
Cttnbp2
cortactin binding protein 2
chr15_-_79164477 3.267 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr10_-_109764840 3.227 ENSMUST00000163071.1
Nav3
neuron navigator 3
chr1_-_56972437 3.227 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr2_+_91945703 3.100 ENSMUST00000178895.1
Gm9821
predicted gene 9821
chr5_+_89027959 2.993 ENSMUST00000130041.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr14_+_45219993 2.967 ENSMUST00000146150.1
Gpr137c
G protein-coupled receptor 137C
chr7_-_79386943 2.926 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr13_+_109632760 2.841 ENSMUST00000135275.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr7_-_118243564 2.792 ENSMUST00000179047.1
ENSMUST00000032891.8
Smg1

SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)

chr6_-_136173492 2.754 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr10_+_13966268 2.553 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr13_-_57907587 2.512 ENSMUST00000172326.1
Spock1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
chr7_+_91090697 2.511 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr7_+_91090728 2.470 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr19_-_57008187 2.468 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr6_-_29507946 2.448 ENSMUST00000101614.3
ENSMUST00000078112.6
Kcp

kielin/chordin-like protein

chr1_-_134955908 2.366 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr9_+_37367354 2.343 ENSMUST00000051839.7
Hepacam
hepatocyte cell adhesion molecule
chr11_-_102897123 2.336 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr9_-_29412204 2.263 ENSMUST00000115237.1
Ntm
neurotrimin
chr3_+_118433797 2.216 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
Gm26871



predicted gene, 26871



chr9_-_56418023 2.210 ENSMUST00000061552.8
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr7_-_79149042 2.202 ENSMUST00000032825.8
ENSMUST00000107409.3
Mfge8

milk fat globule-EGF factor 8 protein

chr15_+_83791939 2.194 ENSMUST00000172115.1
ENSMUST00000172398.1
Mpped1

metallophosphoesterase domain containing 1

chr6_-_13838432 2.188 ENSMUST00000115492.1
Gpr85
G protein-coupled receptor 85
chr3_-_117360876 2.109 ENSMUST00000061071.8
D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr5_+_129584169 2.100 ENSMUST00000031390.8
Mmp17
matrix metallopeptidase 17
chr3_-_116968827 2.097 ENSMUST00000119557.1
Palmd
palmdelphin
chr5_+_89028035 2.092 ENSMUST00000113216.2
ENSMUST00000134303.1
Slc4a4

solute carrier family 4 (anion exchanger), member 4

chrX_+_151198078 2.068 ENSMUST00000184730.1
ENSMUST00000184392.1
ENSMUST00000096285.4
Wnk3


WNK lysine deficient protein kinase 3


chr1_+_159737510 2.042 ENSMUST00000111669.3
Tnr
tenascin R
chr9_-_112217261 2.012 ENSMUST00000159451.1
ENSMUST00000162796.1
ENSMUST00000161097.1
Arpp21


cyclic AMP-regulated phosphoprotein, 21


chr1_-_134955847 1.987 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr19_-_5797410 1.954 ENSMUST00000173314.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr3_-_116968969 1.910 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr11_+_67586520 1.898 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr14_-_54781886 1.895 ENSMUST00000022787.6
Slc7a8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
chr2_+_4300462 1.876 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr2_-_85196697 1.827 ENSMUST00000099930.2
ENSMUST00000111601.1
Lrrc55

leucine rich repeat containing 55

chr17_+_69969217 1.822 ENSMUST00000060072.5
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr11_+_67586675 1.809 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr3_+_28263563 1.796 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
Tnik






TRAF2 and NCK interacting kinase






chr19_-_37207293 1.796 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr11_-_85139939 1.792 ENSMUST00000108075.2
Usp32
ubiquitin specific peptidase 32
chr2_-_104493690 1.787 ENSMUST00000111124.1
Hipk3
homeodomain interacting protein kinase 3
chr2_+_119897212 1.777 ENSMUST00000046717.6
ENSMUST00000110774.1
ENSMUST00000110773.2
ENSMUST00000079934.5
ENSMUST00000156510.1
Mga




MAX gene associated




chr1_-_161034794 1.761 ENSMUST00000177003.1
ENSMUST00000162226.2
ENSMUST00000159250.2
Zbtb37


zinc finger and BTB domain containing 37


chr1_-_132542934 1.719 ENSMUST00000086521.4
Cntn2
contactin 2
chr16_+_72663143 1.719 ENSMUST00000023600.7
Robo1
roundabout homolog 1 (Drosophila)
chr4_+_107802277 1.713 ENSMUST00000106733.2
ENSMUST00000030356.3
ENSMUST00000106732.2
ENSMUST00000126573.1
Lrp8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr8_-_34965631 1.709 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr11_+_84179792 1.690 ENSMUST00000137500.2
ENSMUST00000130012.2
Acaca

acetyl-Coenzyme A carboxylase alpha

chr3_+_26331150 1.683 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr12_+_102949450 1.682 ENSMUST00000179002.1
Unc79
unc-79 homolog (C. elegans)
chr13_+_77135513 1.670 ENSMUST00000168779.1
2210408I21Rik
RIKEN cDNA 2210408I21 gene
chr1_-_172297989 1.648 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr15_+_80711292 1.636 ENSMUST00000067689.7
Tnrc6b
trinucleotide repeat containing 6b
chr11_+_54522872 1.630 ENSMUST00000108895.1
ENSMUST00000101206.3
Rapgef6

Rap guanine nucleotide exchange factor (GEF) 6

chr12_+_4592992 1.619 ENSMUST00000062580.7
Itsn2
intersectin 2
chr17_+_69969073 1.611 ENSMUST00000133983.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr7_-_123500449 1.582 ENSMUST00000042470.7
ENSMUST00000128217.1
Zkscan2

zinc finger with KRAB and SCAN domains 2

chr16_-_37384915 1.578 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr11_-_101785252 1.564 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr2_+_156475844 1.562 ENSMUST00000103135.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr5_-_108549934 1.562 ENSMUST00000129040.1
ENSMUST00000046892.9
Cplx1

complexin 1

chr16_-_36784784 1.552 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr9_-_44234014 1.549 ENSMUST00000037644.6
Cbl
Casitas B-lineage lymphoma
chr5_-_123140135 1.546 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr2_+_165992625 1.539 ENSMUST00000109252.1
ENSMUST00000088095.5
Ncoa3

nuclear receptor coactivator 3

chr16_+_43235856 1.494 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr1_-_133753681 1.488 ENSMUST00000125659.1
ENSMUST00000165602.2
ENSMUST00000048953.7
Atp2b4


ATPase, Ca++ transporting, plasma membrane 4


chr19_-_4989964 1.468 ENSMUST00000056129.7
Npas4
neuronal PAS domain protein 4
chr4_+_42917234 1.467 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr4_+_74013442 1.462 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3

FERM domain containing 3

chr17_+_69969387 1.460 ENSMUST00000146730.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr1_-_69108039 1.456 ENSMUST00000121473.1
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr11_+_57011945 1.430 ENSMUST00000094179.4
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr18_+_65873478 1.417 ENSMUST00000025395.8
ENSMUST00000173530.1
Grp

gastrin releasing peptide

chr4_-_22488296 1.415 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr4_+_102760294 1.413 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
Sgip1



SH3-domain GRB2-like (endophilin) interacting protein 1



chr14_+_62837679 1.409 ENSMUST00000014691.8
Wdfy2
WD repeat and FYVE domain containing 2
chr11_+_77518566 1.406 ENSMUST00000147386.1
Abhd15
abhydrolase domain containing 15
chr11_+_57011798 1.404 ENSMUST00000036315.9
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_-_101226414 1.390 ENSMUST00000100417.2
ENSMUST00000107285.1
ENSMUST00000107284.1
Ezh1


enhancer of zeste homolog 1 (Drosophila)


chr9_-_44881274 1.387 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
Kmt2a


lysine (K)-specific methyltransferase 2A


chr10_+_127759721 1.381 ENSMUST00000073639.5
Rdh1
retinol dehydrogenase 1 (all trans)
chr18_-_34506788 1.376 ENSMUST00000040506.6
Fam13b
family with sequence similarity 13, member B
chr16_-_97170707 1.367 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr4_-_88033328 1.355 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr19_-_4698315 1.352 ENSMUST00000096325.3
Gm960
predicted gene 960
chr12_-_4592927 1.349 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chr10_-_8518801 1.346 ENSMUST00000061601.7
Ust
uronyl-2-sulfotransferase
chr7_+_25306085 1.344 ENSMUST00000119703.1
ENSMUST00000108409.1
Tmem145

transmembrane protein 145

chr7_-_126502094 1.324 ENSMUST00000179818.1
Atxn2l
ataxin 2-like
chr13_+_54949388 1.321 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr17_-_25785533 1.308 ENSMUST00000140738.1
ENSMUST00000145053.1
ENSMUST00000138759.1
ENSMUST00000133071.1
ENSMUST00000077938.3
Haghl




hydroxyacylglutathione hydrolase-like




chr5_-_150594493 1.303 ENSMUST00000016279.7
N4bp2l1
NEDD4 binding protein 2-like 1
chr15_+_76660564 1.293 ENSMUST00000004294.10
Kifc2
kinesin family member C2
chr2_+_156475803 1.290 ENSMUST00000029155.8
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr10_+_75893398 1.288 ENSMUST00000009236.4
Derl3
Der1-like domain family, member 3
chr18_-_6241470 1.286 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr4_-_149307506 1.283 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
Kif1b


kinesin family member 1B


chr11_-_97500340 1.273 ENSMUST00000056955.1
4933428G20Rik
RIKEN cDNA 4933428G20 gene
chr3_-_56183678 1.271 ENSMUST00000029374.6
Nbea
neurobeachin
chr4_-_82705735 1.270 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr1_-_22805994 1.259 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr11_+_35769462 1.258 ENSMUST00000018990.7
Pank3
pantothenate kinase 3
chr19_+_40894692 1.240 ENSMUST00000050092.6
Zfp518a
zinc finger protein 518A
chr5_-_25498702 1.235 ENSMUST00000173073.1
ENSMUST00000045291.7
Kmt2c

lysine (K)-specific methyltransferase 2C

chr2_-_39190687 1.221 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr14_+_54936456 1.220 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr5_-_25498748 1.219 ENSMUST00000173174.1
Kmt2c
lysine (K)-specific methyltransferase 2C
chr10_+_60106452 1.216 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr1_+_135584773 1.215 ENSMUST00000067468.4
Gm4793
predicted gene 4793
chr2_+_120629113 1.213 ENSMUST00000150912.1
ENSMUST00000180041.1
Stard9

START domain containing 9

chr18_+_65430945 1.211 ENSMUST00000049248.5
Malt1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr6_-_28830345 1.208 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr2_-_130906338 1.204 ENSMUST00000146975.1
4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr9_+_32224457 1.201 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr1_+_50927511 1.199 ENSMUST00000081851.3
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr6_+_90465287 1.197 ENSMUST00000113530.1
Klf15
Kruppel-like factor 15
chr14_-_105177263 1.197 ENSMUST00000163499.1
Rbm26
RNA binding motif protein 26
chr4_+_103619580 1.196 ENSMUST00000106827.1
Dab1
disabled 1
chr11_+_69095217 1.184 ENSMUST00000101004.2
Per1
period circadian clock 1
chr17_-_56140333 1.181 ENSMUST00000001256.4
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr11_+_87760533 1.177 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr2_-_45110336 1.168 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr9_-_51008936 1.167 ENSMUST00000176824.1
ENSMUST00000176663.1
ENSMUST00000041375.10
Sik2


salt inducible kinase 2


chr11_+_84179852 1.167 ENSMUST00000136463.2
Acaca
acetyl-Coenzyme A carboxylase alpha
chr10_+_67185730 1.164 ENSMUST00000173689.1
Jmjd1c
jumonji domain containing 1C
chr11_-_104550392 1.164 ENSMUST00000106962.2
Cdc27
cell division cycle 27
chr16_+_43363855 1.154 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr10_+_60106198 1.152 ENSMUST00000121820.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr1_+_34005872 1.149 ENSMUST00000182296.1
Dst
dystonin
chr11_+_3330781 1.147 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr11_+_7063423 1.144 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chr17_+_70522083 1.138 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr18_-_37969742 1.132 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr9_-_44721383 1.126 ENSMUST00000148929.1
ENSMUST00000123406.1
Phldb1

pleckstrin homology-like domain, family B, member 1

chr14_-_49066653 1.124 ENSMUST00000162175.1
Exoc5
exocyst complex component 5
chr4_-_156228540 1.123 ENSMUST00000105571.2
Plekhn1
pleckstrin homology domain containing, family N member 1
chr9_+_100643755 1.122 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr17_+_5492558 1.122 ENSMUST00000089185.4
Zdhhc14
zinc finger, DHHC domain containing 14
chr2_+_65845833 1.120 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr6_+_47835650 1.119 ENSMUST00000079881.4
ENSMUST00000114598.1
Zfp398

zinc finger protein 398

chr11_-_102897146 1.114 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr3_-_97868242 1.098 ENSMUST00000107038.3
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr16_+_20591156 1.095 ENSMUST00000159780.1
Vwa5b2
von Willebrand factor A domain containing 5B2
chr8_+_125995102 1.094 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr13_-_77135416 1.087 ENSMUST00000159462.1
ENSMUST00000151524.2
Ankrd32

ankyrin repeat domain 32

chr2_-_77816758 1.080 ENSMUST00000111831.1
Zfp385b
zinc finger protein 385B
chr11_-_75451083 1.078 ENSMUST00000132442.1
Wdr81
WD repeat domain 81
chr16_+_35983424 1.077 ENSMUST00000173555.1
Kpna1
karyopherin (importin) alpha 1
chr12_+_116281180 1.069 ENSMUST00000100986.2
Esyt2
extended synaptotagmin-like protein 2
chr9_-_112217344 1.067 ENSMUST00000161412.1
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr12_-_91849081 1.061 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
Sel1l


sel-1 suppressor of lin-12-like (C. elegans)


chr14_-_49066368 1.058 ENSMUST00000161504.1
Exoc5
exocyst complex component 5
chr4_-_126753372 1.057 ENSMUST00000030637.7
ENSMUST00000106116.1
Ncdn

neurochondrin

chr4_+_124657646 1.056 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr14_-_100149764 1.053 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr19_+_6306456 1.051 ENSMUST00000025681.7
Cdc42bpg
CDC42 binding protein kinase gamma (DMPK-like)
chr3_-_103791075 1.051 ENSMUST00000106845.2
ENSMUST00000029438.8
ENSMUST00000121324.1
Hipk1


homeodomain interacting protein kinase 1


chr13_+_58807884 1.051 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr1_+_87327008 1.046 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr9_-_110476637 1.044 ENSMUST00000111934.1
ENSMUST00000068025.6
Klhl18

kelch-like 18

chr17_-_25785324 1.043 ENSMUST00000150324.1
Haghl
hydroxyacylglutathione hydrolase-like
chr1_+_165301863 1.040 ENSMUST00000178700.1
Gpr161
G protein-coupled receptor 161
chr15_+_102503722 1.038 ENSMUST00000096145.4
Gm10337
predicted gene 10337
chr16_+_43364145 1.036 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr11_+_54522847 1.036 ENSMUST00000102743.3
Rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr9_-_82975475 1.035 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr2_-_181156993 1.034 ENSMUST00000055990.7
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr13_+_42866247 1.024 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr19_+_44931119 1.013 ENSMUST00000096053.3
Fam178a
family with sequence similarity 178, member A
chr12_-_87200200 1.012 ENSMUST00000037418.5
Tmed8
transmembrane emp24 domain containing 8
chr18_+_37513652 1.010 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr3_-_84259812 1.010 ENSMUST00000107691.1
Trim2
tripartite motif-containing 2
chr12_+_16894894 1.005 ENSMUST00000020904.6
Rock2
Rho-associated coiled-coil containing protein kinase 2
chr11_+_75531690 1.004 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr9_-_59036387 1.003 ENSMUST00000068664.5
Neo1
neogenin
chrX_-_60403947 0.999 ENSMUST00000033480.6
ENSMUST00000101527.2
Atp11c

ATPase, class VI, type 11C

chr15_+_82256023 0.993 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr12_-_83439910 0.989 ENSMUST00000177801.1
Dpf3
D4, zinc and double PHD fingers, family 3
chrX_+_99975570 0.987 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr1_+_177444653 0.985 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr6_+_21215472 0.982 ENSMUST00000081542.5
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr9_+_26733845 0.980 ENSMUST00000115269.2
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr9_-_96752822 0.980 ENSMUST00000152594.1
Zbtb38
zinc finger and BTB domain containing 38
chr16_-_22439719 0.979 ENSMUST00000079601.6
Etv5
ets variant gene 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0007521 muscle cell fate determination(GO:0007521)
1.1 6.7 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
1.0 4.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.9 3.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.9 3.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.8 1.5 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.7 2.9 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.7 2.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.6 1.8 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.6 1.7 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
0.6 1.7 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.6 1.7 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.6 7.3 GO:0070842 aggresome assembly(GO:0070842)
0.5 1.6 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.5 2.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.5 2.0 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.5 1.5 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.5 0.5 GO:0001941 postsynaptic membrane organization(GO:0001941)
0.5 1.5 GO:0010751 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.5 2.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.5 1.4 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.4 2.2 GO:0042891 antibiotic transport(GO:0042891)
0.4 1.6 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.4 1.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 1.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.4 2.0 GO:0035063 nuclear speck organization(GO:0035063)
0.4 1.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 2.5 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.4 1.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 3.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.4 2.8 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.3 1.4 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.3 1.7 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.3 1.0 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3 1.0 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.3 1.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 1.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.3 1.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 0.6 GO:0060596 mammary placode formation(GO:0060596)
0.3 0.3 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.3 1.2 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.3 5.1 GO:0015701 bicarbonate transport(GO:0015701)
0.3 2.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 0.9 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.3 1.5 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.3 1.7 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.3 2.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.3 1.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.3 0.8 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.3 1.3 GO:0019236 response to pheromone(GO:0019236)
0.3 1.1 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.3 2.1 GO:0042756 drinking behavior(GO:0042756)
0.3 1.8 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.3 3.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.3 3.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.2 1.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.2 1.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 0.9 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.5 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.2 0.7 GO:0071579 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579)
0.2 3.3 GO:0046548 retinal rod cell development(GO:0046548)
0.2 2.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.2 0.9 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 0.7 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 2.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 3.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 0.7 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.2 1.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.2 2.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.6 GO:0050975 sensory perception of touch(GO:0050975)
0.2 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 0.6 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.2 1.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 3.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 0.6 GO:0046549 retinal cone cell development(GO:0046549)
0.2 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 0.6 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.2 5.7 GO:0007616 long-term memory(GO:0007616)
0.2 0.6 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.2 0.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.2 0.5 GO:0006553 lysine metabolic process(GO:0006553)
0.2 1.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 0.9 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 0.8 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.2 1.0 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 1.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 1.0 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.2 1.8 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 2.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 1.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 3.1 GO:0030033 microvillus assembly(GO:0030033)
0.2 0.8 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2 0.8 GO:0006868 glutamine transport(GO:0006868) cellular response to potassium ion starvation(GO:0051365)
0.2 0.8 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 2.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 0.8 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.2 0.9 GO:0016198 axon choice point recognition(GO:0016198)
0.2 0.8 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 1.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 0.5 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.1 1.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.4 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.7 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 0.8 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 1.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.5 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.4 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 0.5 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.6 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 1.3 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.6 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.5 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.4 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.1 0.5 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.1 0.5 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.5 GO:0033005 positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 2.9 GO:0061157 mRNA destabilization(GO:0061157)
0.1 8.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.5 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.1 0.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.5 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 1.1 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.9 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.5 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.9 GO:0043084 penile erection(GO:0043084)
0.1 2.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.7 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.3 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 0.7 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.2 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
0.1 2.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 1.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.5 GO:0048050 post-embryonic eye morphogenesis(GO:0048050) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.3 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 1.2 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.5 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 1.7 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.5 GO:0015879 carnitine transport(GO:0015879)
0.1 0.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.7 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.5 GO:0048702 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.4 GO:1904177 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) regulation of adipose tissue development(GO:1904177)
0.1 1.8 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.4 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 1.3 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.2 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 3.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 1.0 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.6 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.4 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.1 GO:0021546 rhombomere development(GO:0021546)
0.1 0.8 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 2.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.2 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.1 0.3 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.6 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.5 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.4 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 0.3 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.5 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.1 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 1.3 GO:0032288 myelin assembly(GO:0032288)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 1.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 5.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 1.1 GO:0071800 podosome assembly(GO:0071800)
0.1 0.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.9 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.1 2.9 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 3.3 GO:0015807 L-amino acid transport(GO:0015807)
0.1 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.9 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.6 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.1 1.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.5 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.0 GO:0044804 nucleophagy(GO:0044804)
0.1 1.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.1 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 1.2 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 1.2 GO:0071625 vocalization behavior(GO:0071625)
0.0 2.3 GO:0048278 vesicle docking(GO:0048278)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.7 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 1.0 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.5 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 1.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.8 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.5 GO:0043113 receptor clustering(GO:0043113)
0.0 0.0 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.0 0.8 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 2.7 GO:0007338 single fertilization(GO:0007338)
0.0 3.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 4.3 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.7 GO:0021681 cerebellar granular layer development(GO:0021681)
0.0 0.2 GO:0098543 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 1.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.9 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.5 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.3 GO:0033572 transferrin transport(GO:0033572)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.1 GO:0045453 bone resorption(GO:0045453)
0.0 0.6 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.0 GO:2000642 negative regulation of vacuolar transport(GO:1903336) negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.1 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.9 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 1.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.3 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.5 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.4 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.2 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.4 GO:0097484 dendrite extension(GO:0097484)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 2.7 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0007032 endosome organization(GO:0007032)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.4 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.2 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 0.7 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.0 GO:0030862 regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.3 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.4 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0033578 protein glycosylation in Golgi(GO:0033578) GDP-L-fucose metabolic process(GO:0046368)
0.0 1.0 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.9 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 1.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0051297 microtubule organizing center organization(GO:0031023) centrosome organization(GO:0051297)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.1 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.8 12.5 GO:0005614 interstitial matrix(GO:0005614)
0.7 2.0 GO:0072534 perineuronal net(GO:0072534)
0.5 2.8 GO:0044308 axonal spine(GO:0044308)
0.4 1.3 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.4 1.7 GO:0097441 basilar dendrite(GO:0097441)
0.4 1.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.4 3.0 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.3 1.2 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.3 1.1 GO:0031673 H zone(GO:0031673)
0.3 0.9 GO:0036128 CatSper complex(GO:0036128)
0.3 4.2 GO:0043083 synaptic cleft(GO:0043083)
0.3 1.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 1.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 4.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 1.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 0.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 0.6 GO:0016939 kinesin II complex(GO:0016939)
0.2 0.5 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.2 1.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 2.6 GO:1990635 proximal dendrite(GO:1990635)
0.2 2.0 GO:0016600 flotillin complex(GO:0016600)
0.2 1.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.2 1.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 0.3 GO:0097513 myosin II filament(GO:0097513)
0.1 2.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.1 1.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.3 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 3.5 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.6 GO:0031523 Myb complex(GO:0031523)
0.1 3.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 2.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.1 GO:0045180 basal cortex(GO:0045180)
0.1 7.7 GO:0031594 neuromuscular junction(GO:0031594)
0.1 3.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 2.7 GO:0030673 axolemma(GO:0030673)
0.1 1.9 GO:0000145 exocyst(GO:0000145)
0.1 3.6 GO:0031672 A band(GO:0031672)
0.1 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 4.0 GO:0005871 kinesin complex(GO:0005871)
0.1 20.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 1.5 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 3.4 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.3 GO:0001651 dense fibrillar component(GO:0001651)
0.1 1.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.9 GO:0097542 ciliary tip(GO:0097542)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 0.5 GO:0097433 dense body(GO:0097433)
0.1 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.2 GO:0042629 mast cell granule(GO:0042629)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.1 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.3 GO:0032589 neuron projection membrane(GO:0032589)
0.1 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 3.6 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 9.2 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.1 GO:0071565 nBAF complex(GO:0071565)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 1.4 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 1.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.6 GO:0043218 compact myelin(GO:0043218)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.6 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 3.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 2.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.9 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.8 GO:0030016 myofibril(GO:0030016)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.1 GO:0005884 actin filament(GO:0005884)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0032994 protein-lipid complex(GO:0032994)
0.0 14.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.4 GO:0045177 apical part of cell(GO:0045177)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.7 GO:0030027 lamellipodium(GO:0030027)
0.0 1.1 GO:0005770 late endosome(GO:0005770)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.0 2.9 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.8 6.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.7 2.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.6 3.9 GO:0045545 syndecan binding(GO:0045545)
0.5 1.6 GO:0042936 dipeptide transporter activity(GO:0042936)
0.5 2.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.5 2.9 GO:0019841 retinol binding(GO:0019841)
0.5 3.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 1.7 GO:0038025 reelin receptor activity(GO:0038025)
0.4 1.3 GO:0038132 neuregulin binding(GO:0038132)
0.4 3.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.4 2.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.4 2.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.4 2.6 GO:0019534 toxin transporter activity(GO:0019534)
0.4 6.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 1.0 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.3 1.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.3 8.6 GO:0001968 fibronectin binding(GO:0001968)
0.3 1.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 3.7 GO:0070097 delta-catenin binding(GO:0070097)
0.3 0.9 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.3 4.6 GO:0003680 AT DNA binding(GO:0003680)
0.3 2.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.3 0.8 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.3 0.8 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 2.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 2.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 1.6 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.2 0.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 1.3 GO:0005042 netrin receptor activity(GO:0005042)
0.2 0.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 0.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 4.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 2.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 1.8 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 0.8 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 0.6 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 1.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 1.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 1.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.8 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.2 1.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 1.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 2.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 1.6 GO:1990239 steroid hormone binding(GO:1990239)
0.2 2.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 1.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 2.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 0.5 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2 0.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 0.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 0.6 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.2 0.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 2.7 GO:0046625 sphingolipid binding(GO:0046625)
0.2 0.8 GO:0070330 aromatase activity(GO:0070330)
0.1 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.4 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 1.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.4 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.6 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 1.8 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.5 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 2.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.4 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 2.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 3.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 0.5 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)
0.1 0.4 GO:0008169 C-methyltransferase activity(GO:0008169)
0.1 0.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 2.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 3.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 2.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.6 GO:0043559 insulin binding(GO:0043559)
0.1 0.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.8 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 1.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 1.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.3 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.5 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 3.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0016151 nickel cation binding(GO:0016151)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.3 GO:0031489 myosin V binding(GO:0031489)
0.1 0.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 2.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.3 GO:0015093 iron ion transmembrane transporter activity(GO:0005381) ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 3.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 1.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 3.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 2.9 GO:0005178 integrin binding(GO:0005178)
0.0 4.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 1.5 GO:0043621 protein self-association(GO:0043621)
0.0 1.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.7 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.6 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.1 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 1.4 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 3.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0004532 exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 4.7 GO:0016887 ATPase activity(GO:0016887)
0.0 2.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.5 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.6 PID_REELIN_PATHWAY Reelin signaling pathway
0.2 2.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 1.9 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.1 5.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 4.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.4 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 0.4 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.5 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 4.0 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 3.3 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.6 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.1 2.7 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 3.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.9 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 1.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 0.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.2 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 1.4 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.8 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.5 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.0 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.5 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.0 0.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.2 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.7 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.2 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 0.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.3 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.3 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.2 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 5.5 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 4.9 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 1.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 1.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.2 1.4 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.2 2.0 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 1.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 5.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 4.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.7 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.3 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.8 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.4 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 1.1 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.7 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.7 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 5.9 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.6 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 2.9 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 1.4 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 2.2 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 2.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 0.4 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 0.4 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 2.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.9 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.8 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 0.9 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 6.0 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 0.8 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.2 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.1 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.9 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 3.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.3 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 3.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 3.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.9 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.5 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.9 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.0 0.6 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 0.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants