Motif ID: Pax7

Z-value: 0.344


Transcription factors associated with Pax7:

Gene SymbolEntrez IDGene Name
Pax7 ENSMUSG00000028736.7 Pax7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax7mm10_v2_chr4_-_139832920_139833007-0.155.6e-01Click!


Activity profile for motif Pax7.

activity profile for motif Pax7


Sorted Z-values histogram for motif Pax7

Sorted Z-values for motif Pax7



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_67113909 1.363 ENSMUST00000092640.5
 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr8_-_34965631 0.619 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr9_-_96719404 0.574 ENSMUST00000140121.1
 Zbtb38
zinc finger and BTB domain containing 38
chr3_+_55461758 0.533 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr2_+_32727682 0.529 ENSMUST00000113242.2
 Sh2d3c
SH2 domain containing 3C
chr4_+_136286061 0.507 ENSMUST00000069195.4
ENSMUST00000130658.1
 Zfp46

zinc finger protein 46

chr1_+_72284367 0.506 ENSMUST00000027380.5
ENSMUST00000141783.1
 Tmem169

transmembrane protein 169

chr10_+_85386813 0.489 ENSMUST00000105307.1
ENSMUST00000020231.3
 Btbd11

BTB (POZ) domain containing 11

chr10_-_62379852 0.476 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
 Hk1



hexokinase 1



chr4_+_102589687 0.446 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chr9_-_96719549 0.433 ENSMUST00000128269.1
 Zbtb38
zinc finger and BTB domain containing 38
chr5_+_26817357 0.390 ENSMUST00000071500.6
 Dpp6
dipeptidylpeptidase 6
chr2_+_65620829 0.383 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr13_+_76579670 0.337 ENSMUST00000126960.1
ENSMUST00000109583.2
 Mctp1

multiple C2 domains, transmembrane 1

chr19_+_8802486 0.316 ENSMUST00000172175.1
 Zbtb3
zinc finger and BTB domain containing 3
chr4_+_108719649 0.307 ENSMUST00000178992.1
 3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr11_-_87359011 0.279 ENSMUST00000055438.4
 Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr11_-_115276973 0.236 ENSMUST00000021078.2
 Fdxr
ferredoxin reductase
chr2_+_125136692 0.176 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr15_-_37459327 0.174 ENSMUST00000119730.1
ENSMUST00000120746.1
 Ncald

neurocalcin delta

chr1_-_55226768 0.156 ENSMUST00000027121.8
ENSMUST00000114428.2
 Rftn2

raftlin family member 2

chr14_-_76110760 0.155 ENSMUST00000022585.3
 Gpalpp1
GPALPP motifs containing 1
chr8_+_107031218 0.144 ENSMUST00000034388.9
 Vps4a
vacuolar protein sorting 4a (yeast)
chr14_+_55560010 0.143 ENSMUST00000147981.1
ENSMUST00000133256.1
 Dcaf11

DDB1 and CUL4 associated factor 11

chr2_-_150255591 0.127 ENSMUST00000063463.5
 Gm21994
predicted gene 21994
chr9_-_20959785 0.119 ENSMUST00000177754.1
 Dnmt1
DNA methyltransferase (cytosine-5) 1
chr2_-_37359274 0.108 ENSMUST00000009174.8
 Pdcl
phosducin-like
chr18_+_38993126 0.106 ENSMUST00000097593.2
 Arhgap26
Rho GTPase activating protein 26
chr7_-_98656530 0.098 ENSMUST00000038359.4
 2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr6_+_145934113 0.094 ENSMUST00000032383.7
 Sspn
sarcospan
chr16_+_58408443 0.085 ENSMUST00000046663.7
 Dcbld2
discoidin, CUB and LCCL domain containing 2
chr5_-_92348871 0.081 ENSMUST00000038816.6
ENSMUST00000118006.1
 Cxcl10

chemokine (C-X-C motif) ligand 10

chr7_-_46667375 0.066 ENSMUST00000107669.2
 Tph1
tryptophan hydroxylase 1
chr11_+_43682038 0.064 ENSMUST00000094294.4
 Pwwp2a
PWWP domain containing 2A
chr19_+_41933464 0.057 ENSMUST00000026154.7
 Zdhhc16
zinc finger, DHHC domain containing 16
chr7_-_45510400 0.050 ENSMUST00000033096.7
 Nucb1
nucleobindin 1
chr13_+_67833235 0.045 ENSMUST00000060609.7
 Gm10037
predicted gene 10037
chr3_+_32436376 0.035 ENSMUST00000108242.1
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr12_+_72441852 0.031 ENSMUST00000162159.1
 Lrrc9
leucine rich repeat containing 9
chr9_+_21955747 0.030 ENSMUST00000053583.5
 Swsap1
SWIM type zinc finger 7 associated protein 1
chr2_-_33718789 0.027 ENSMUST00000130532.1
 9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr6_+_37870786 0.023 ENSMUST00000120428.1
ENSMUST00000031859.7
 Trim24

tripartite motif-containing 24

chr14_+_55559993 0.022 ENSMUST00000117236.1
 Dcaf11
DDB1 and CUL4 associated factor 11
chr7_-_137410717 0.017 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
 9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr3_-_87174657 0.016 ENSMUST00000159976.1
ENSMUST00000107618.2
 Kirrel

kin of IRRE like (Drosophila)

chr19_-_41933276 0.009 ENSMUST00000075280.4
ENSMUST00000112123.2
 Exosc1

exosome component 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.5 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.2 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.0 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.0 0.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.0 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.5 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events