Motif ID: Pgr_Nr3c1

Z-value: 0.663

Transcription factors associated with Pgr_Nr3c1:

Gene SymbolEntrez IDGene Name
Nr3c1 ENSMUSG00000024431.8 Nr3c1
Pgr ENSMUSG00000031870.10 Pgr

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c1mm10_v2_chr18_-_39489776_39489868-0.561.7e-02Click!


Activity profile for motif Pgr_Nr3c1.

activity profile for motif Pgr_Nr3c1


Sorted Z-values histogram for motif Pgr_Nr3c1

Sorted Z-values for motif Pgr_Nr3c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pgr_Nr3c1

PNG image of the network

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Top targets:


Showing 1 to 20 of 129 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 7.307 ENSMUST00000075312.3
 Ttr
transthyretin
chr10_+_97565436 3.712 ENSMUST00000038160.4
 Lum
lumican
chr9_+_91368970 1.952 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr9_+_91368811 1.775 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr7_+_144838590 1.386 ENSMUST00000105898.1
 Fgf3
fibroblast growth factor 3
chr3_-_33082004 0.968 ENSMUST00000108225.3
 Pex5l
peroxisomal biogenesis factor 5-like
chr2_-_30474199 0.930 ENSMUST00000065134.2
 Ier5l
immediate early response 5-like
chr3_-_146839365 0.895 ENSMUST00000084614.3
 Gm10288
predicted gene 10288
chr1_+_109993982 0.804 ENSMUST00000027542.6
 Cdh7
cadherin 7, type 2
chr7_-_75308373 0.739 ENSMUST00000085164.5
 Sv2b
synaptic vesicle glycoprotein 2 b
chr18_-_62756275 0.690 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr14_-_16575456 0.666 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr10_-_63421739 0.661 ENSMUST00000054760.4
 Gm7075
predicted gene 7075
chr1_-_171240055 0.650 ENSMUST00000131286.1
 Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr10_+_14523062 0.638 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr4_-_44710408 0.558 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
 Pax5









paired box gene 5









chr14_+_75845093 0.554 ENSMUST00000110894.2
 Tpt1
tumor protein, translationally-controlled 1
chr14_+_75845296 0.539 ENSMUST00000142061.1
 Tpt1
tumor protein, translationally-controlled 1
chr2_-_80128834 0.534 ENSMUST00000102654.4
ENSMUST00000102655.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr1_+_135232045 0.497 ENSMUST00000110798.3
 Gm4204
predicted gene 4204

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 7.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.9 3.7 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 1.5 GO:0030916 otic vesicle formation(GO:0030916)
0.2 1.2 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.3 1.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.7 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.6 GO:0021670 lateral ventricle development(GO:0021670) negative regulation of histone H3-K9 methylation(GO:0051573)
0.2 0.5 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 0.5 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.1 0.5 GO:0048386 positive regulation of keratinocyte differentiation(GO:0045618) positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.4 GO:0046104 thymidine metabolic process(GO:0046104)
0.1 0.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0051798 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 1.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 1.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 0.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 7.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 2.9 GO:0005518 collagen binding(GO:0005518)
0.1 1.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 1.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.7 GO:0048038 quinone binding(GO:0048038)
0.0 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 0.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.5 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.9 PID_P73PATHWAY p73 transcription factor network
0.0 0.2 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.3 REACTOME_AMYLOIDS Genes involved in Amyloids
0.4 3.7 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.4 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.8 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle