Motif ID: Phox2a

Z-value: 0.586


Transcription factors associated with Phox2a:

Gene SymbolEntrez IDGene Name
Phox2a ENSMUSG00000007946.9 Phox2a



Activity profile for motif Phox2a.

activity profile for motif Phox2a


Sorted Z-values histogram for motif Phox2a

Sorted Z-values for motif Phox2a



Network of associatons between targets according to the STRING database.



First level regulatory network of Phox2a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_60893430 2.935 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr2_-_168767136 2.883 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr2_-_168767029 2.597 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr2_+_20737306 2.139 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr9_+_119063429 1.998 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr6_-_147264124 1.672 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr13_-_102905740 1.159 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr13_-_102906046 1.095 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr1_-_172027269 1.047 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr8_-_84662841 0.975 ENSMUST00000060427.4
Ier2
immediate early response 2
chrM_+_2743 0.932 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr1_-_89933290 0.664 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr7_-_45103747 0.485 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr7_-_38019505 0.315 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr4_+_134930898 0.208 ENSMUST00000030622.2
Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr11_+_116843278 0.170 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr19_-_41933276 0.121 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chr4_-_14621669 0.100 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chrX_+_9885622 0.058 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr4_-_14621494 0.023 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr16_-_42340595 0.009 ENSMUST00000102817.4
Gap43
growth associated protein 43

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 5.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 1.7 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 2.9 GO:0007530 sex determination(GO:0007530)
0.1 0.7 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 2.0 GO:0051693 actin filament capping(GO:0051693)
0.0 0.9 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 2.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.0 GO:0071774 response to fibroblast growth factor(GO:0071774)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0060187 cell pole(GO:0060187)
0.0 5.5 GO:0000792 heterochromatin(GO:0000792)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 3.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 5.5 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease