Motif ID: Pitx2_Otx2

Z-value: 2.205

Transcription factors associated with Pitx2_Otx2:

Gene SymbolEntrez IDGene Name
Otx2 ENSMUSG00000021848.9 Otx2
Pitx2 ENSMUSG00000028023.10 Pitx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Otx2mm10_v2_chr14_-_48665098_486652460.753.3e-04Click!
Pitx2mm10_v2_chr3_+_129213920_1292139380.361.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx2_Otx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_164562579 11.436 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr7_-_75782080 8.142 ENSMUST00000181224.1
AU020206
expressed sequence AU020206
chr6_+_34354119 6.961 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr6_-_88898664 6.841 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr11_-_106998483 6.677 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr17_+_35861318 6.477 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr9_+_119357381 6.127 ENSMUST00000039610.8
Xylb
xylulokinase homolog (H. influenzae)
chr7_+_16781341 5.846 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr17_+_87635974 5.642 ENSMUST00000053577.8
Epcam
epithelial cell adhesion molecule
chr14_-_20181773 5.570 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr1_-_175979114 5.541 ENSMUST00000104983.1
B020018G12Rik
RIKEN cDNA B020018G12 gene
chr1_+_135232045 5.203 ENSMUST00000110798.3
Gm4204
predicted gene 4204
chr9_-_100486788 5.005 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chr7_-_34812677 4.913 ENSMUST00000078686.6
Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr11_-_60811228 4.788 ENSMUST00000018744.8
Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr6_+_56017489 4.729 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr3_+_85915722 4.719 ENSMUST00000054148.7
Gm9790
predicted gene 9790
chr11_+_97029925 4.692 ENSMUST00000021249.4
Scrn2
secernin 2
chr10_-_128180265 4.641 ENSMUST00000099139.1
Rbms2
RNA binding motif, single stranded interacting protein 2
chr8_+_33653238 4.603 ENSMUST00000033992.8
Gsr
glutathione reductase
chr3_+_131112785 4.568 ENSMUST00000098611.3
Lef1
lymphoid enhancer binding factor 1
chr17_+_80127447 4.409 ENSMUST00000039205.4
Galm
galactose mutarotase
chr9_-_70421533 4.331 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr7_-_143460989 4.223 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr17_+_35861343 4.180 ENSMUST00000172931.1
Nrm
nurim (nuclear envelope membrane protein)
chr3_+_116878227 4.138 ENSMUST00000040260.6
Frrs1
ferric-chelate reductase 1
chr7_-_99353104 4.086 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr16_+_59471775 3.994 ENSMUST00000023407.5
ENSMUST00000120667.1
ENSMUST00000120674.1
Mina


myc induced nuclear antigen


chr16_+_30065333 3.956 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr6_-_124779686 3.857 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr18_-_60501983 3.819 ENSMUST00000042710.6
Smim3
small integral membrane protein 3
chrM_+_8600 3.811 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr8_+_114133557 3.762 ENSMUST00000073521.5
ENSMUST00000066514.6
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr5_-_135251209 3.746 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr8_-_71511762 3.720 ENSMUST00000048452.4
Plvap
plasmalemma vesicle associated protein
chr19_-_41896132 3.702 ENSMUST00000038677.3
Rrp12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr18_+_34751803 3.688 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr14_+_55824795 3.683 ENSMUST00000024179.5
ENSMUST00000172271.1
Nfatc4

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4

chr6_-_124814288 3.681 ENSMUST00000172132.2
Tpi1
triosephosphate isomerase 1
chr6_-_23248264 3.667 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr9_+_22454290 3.627 ENSMUST00000168332.1
Gm17545
predicted gene, 17545
chr4_-_117182623 3.595 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr2_-_28466266 3.582 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr7_+_16992708 3.537 ENSMUST00000094805.4
Ccdc8
coiled-coil domain containing 8
chr10_-_77089428 3.521 ENSMUST00000156009.1
Col18a1
collagen, type XVIII, alpha 1
chr8_+_114133635 3.494 ENSMUST00000147605.1
ENSMUST00000134593.1
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr1_+_92906959 3.476 ENSMUST00000060913.6
Dusp28
dual specificity phosphatase 28
chr8_-_116993459 3.457 ENSMUST00000040484.5
Gcsh
glycine cleavage system protein H (aminomethyl carrier)
chr18_+_34736359 3.418 ENSMUST00000105038.2
Gm3550
predicted gene 3550
chr18_-_74207771 3.400 ENSMUST00000040188.8
ENSMUST00000177604.1
Ska1

spindle and kinetochore associated complex subunit 1

chr4_-_149137536 3.333 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
Apitd1



apoptosis-inducing, TAF9-like domain 1



chr14_-_47411666 3.304 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr14_+_74735641 3.244 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr11_-_58801944 3.218 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr1_-_153549697 3.201 ENSMUST00000041874.7
Npl
N-acetylneuraminate pyruvate lyase
chr2_+_157737401 3.201 ENSMUST00000029178.6
Ctnnbl1
catenin, beta like 1
chr7_-_122101735 3.195 ENSMUST00000139456.1
ENSMUST00000106471.2
ENSMUST00000123296.1
ENSMUST00000033157.3
Ndufab1



NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1



chr8_+_127447669 3.169 ENSMUST00000159511.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr4_+_155704789 3.161 ENSMUST00000030905.2
Ssu72
Ssu72 RNA polymerase II CTD phosphatase homolog (yeast)
chr11_+_115403734 3.151 ENSMUST00000153983.1
ENSMUST00000106539.3
ENSMUST00000103036.4
Ict1


immature colon carcinoma transcript 1


chr11_+_117199641 3.151 ENSMUST00000093907.4
Sept9
septin 9
chr15_+_80948484 3.121 ENSMUST00000023043.2
ENSMUST00000168756.1
ENSMUST00000164806.1
Adsl


adenylosuccinate lyase


chr8_+_85026833 3.111 ENSMUST00000047281.8
2310036O22Rik
RIKEN cDNA 2310036O22 gene
chr9_-_114982739 3.068 ENSMUST00000053150.5
Gm9846
predicted gene 9846
chr15_+_99006056 3.066 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr7_-_118116128 3.039 ENSMUST00000128482.1
ENSMUST00000131840.1
Rps15a

ribosomal protein S15A

chr17_+_29090969 3.026 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr10_+_128238034 2.974 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr2_+_26586607 2.964 ENSMUST00000174211.1
ENSMUST00000145575.2
ENSMUST00000173920.1
Egfl7


EGF-like domain 7


chr11_+_101442298 2.959 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr19_+_6061176 2.933 ENSMUST00000162726.3
Znhit2
zinc finger, HIT domain containing 2
chr6_-_72235559 2.920 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr5_+_74195281 2.884 ENSMUST00000051937.7
Rasl11b
RAS-like, family 11, member B
chr8_+_84901928 2.867 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr7_+_16891755 2.847 ENSMUST00000078182.4
Gng8
guanine nucleotide binding protein (G protein), gamma 8
chr9_+_54950782 2.837 ENSMUST00000034848.7
Psma4
proteasome (prosome, macropain) subunit, alpha type 4
chr10_+_82954344 2.829 ENSMUST00000095396.3
Gm4799
predicted gene 4799
chr17_+_50698525 2.816 ENSMUST00000061681.7
Gm7334
predicted gene 7334
chr7_-_100514800 2.778 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr15_-_36308956 2.777 ENSMUST00000090170.4
Rpl7a-ps3
ribosomal protein L7A, pseudogene 3
chr5_-_72587544 2.775 ENSMUST00000031124.4
Gm5868
predicted gene 5868
chr11_-_106999482 2.757 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr6_+_42349826 2.723 ENSMUST00000070635.6
Zyx
zyxin
chr10_+_80292453 2.713 ENSMUST00000068408.7
ENSMUST00000062674.6
Rps15

ribosomal protein S15

chr15_-_102667749 2.702 ENSMUST00000075630.3
Atp5g2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chr14_-_47418407 2.689 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr16_+_14906622 2.689 ENSMUST00000090277.1
Efcab1
EF hand calcium binding domain 1
chr3_-_36571952 2.677 ENSMUST00000029270.3
Ccna2
cyclin A2
chr12_-_69159109 2.659 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr10_-_80320506 2.624 ENSMUST00000020341.8
2310011J03Rik
RIKEN cDNA 2310011J03 gene
chr5_+_134582690 2.622 ENSMUST00000023867.6
Rfc2
replication factor C (activator 1) 2
chr3_-_97610156 2.604 ENSMUST00000029730.4
Chd1l
chromodomain helicase DNA binding protein 1-like
chr11_-_120796369 2.587 ENSMUST00000143139.1
ENSMUST00000129955.1
ENSMUST00000026151.4
ENSMUST00000167023.1
ENSMUST00000106133.1
ENSMUST00000106135.1
Dus1l





dihydrouridine synthase 1-like (S. cerevisiae)





chr11_-_84068554 2.581 ENSMUST00000164891.1
Dusp14
dual specificity phosphatase 14
chr8_+_70131327 2.576 ENSMUST00000095273.5
Nr2c2ap
nuclear receptor 2C2-associated protein
chr16_-_4719078 2.550 ENSMUST00000120056.1
ENSMUST00000074970.7
Nmral1

NmrA-like family domain containing 1

chr8_-_105707933 2.547 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr5_+_137778849 2.532 ENSMUST00000126126.1
ENSMUST00000031739.4
Ppp1r35

protein phosphatase 1, regulatory subunit 35

chr17_-_35673738 2.527 ENSMUST00000001565.8
Gtf2h4
general transcription factor II H, polypeptide 4
chr11_+_44617310 2.522 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr6_+_42350000 2.485 ENSMUST00000164375.1
Zyx
zyxin
chr6_+_83349446 2.484 ENSMUST00000136501.1
Bola3
bolA-like 3 (E. coli)
chr3_-_153912966 2.480 ENSMUST00000089950.4
Rabggtb
RAB geranylgeranyl transferase, b subunit
chr16_-_4719148 2.463 ENSMUST00000115851.3
Nmral1
NmrA-like family domain containing 1
chr14_-_8309770 2.462 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
Fam107a


family with sequence similarity 107, member A


chr2_-_118256929 2.448 ENSMUST00000028820.6
ENSMUST00000028821.3
Fsip1

fibrous sheath-interacting protein 1

chr17_-_70924958 2.440 ENSMUST00000180468.1
Gm26510
predicted gene, 26510
chr5_+_110330697 2.438 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr6_-_131293187 2.437 ENSMUST00000032307.5
Magohb
mago-nashi homolog B (Drosophila)
chr7_+_66060338 2.430 ENSMUST00000153609.1
Snrpa1
small nuclear ribonucleoprotein polypeptide A'
chr11_-_93965957 2.426 ENSMUST00000021220.3
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr14_+_27039001 2.412 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr5_+_99979061 2.408 ENSMUST00000046721.1
4930524J08Rik
RIKEN cDNA 4930524J08 gene
chr3_+_95111013 2.391 ENSMUST00000009102.8
Vps72
vacuolar protein sorting 72 (yeast)
chr8_+_70673198 2.384 ENSMUST00000034311.8
Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_+_46841475 2.362 ENSMUST00000147535.1
Ldha
lactate dehydrogenase A
chr11_+_101448403 2.346 ENSMUST00000010502.6
Ifi35
interferon-induced protein 35
chr17_-_25880236 2.337 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr10_-_92722356 2.330 ENSMUST00000020163.6
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr4_+_89137122 2.310 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr9_-_20898592 2.301 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr9_-_96478660 2.291 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr5_+_73006897 2.285 ENSMUST00000031127.7
Slc10a4
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr11_-_106999369 2.269 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr11_-_84068766 2.267 ENSMUST00000018792.5
Dusp14
dual specificity phosphatase 14
chr11_-_84069179 2.262 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr14_+_67745229 2.249 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr4_+_80910646 2.242 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chr3_+_129878571 2.233 ENSMUST00000029629.8
Pla2g12a
phospholipase A2, group XIIA
chr2_-_151973840 2.228 ENSMUST00000109865.1
ENSMUST00000109864.1
Fam110a

family with sequence similarity 110, member A

chr11_+_75999912 2.227 ENSMUST00000066408.5
1700016K19Rik
RIKEN cDNA 1700016K19 gene
chr3_+_55112080 2.218 ENSMUST00000044116.7
ENSMUST00000107971.2
ENSMUST00000118118.1
Spg20


spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)


chr15_+_79670856 2.197 ENSMUST00000023062.3
Tomm22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr11_+_69995874 2.183 ENSMUST00000101526.2
Phf23
PHD finger protein 23
chr7_+_45163915 2.182 ENSMUST00000085374.5
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr4_+_41135743 2.181 ENSMUST00000040008.3
Ube2r2
ubiquitin-conjugating enzyme E2R 2
chr7_-_126792469 2.180 ENSMUST00000032936.6
Ppp4c
protein phosphatase 4, catalytic subunit
chr7_-_38107490 2.177 ENSMUST00000108023.3
Ccne1
cyclin E1
chr16_+_38562806 2.172 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr18_-_20682963 2.149 ENSMUST00000165229.2
Gm10269
predicted gene 10269
chr3_-_90243073 2.148 ENSMUST00000107369.1
Creb3l4
cAMP responsive element binding protein 3-like 4
chr17_+_80224441 2.144 ENSMUST00000069486.6
Gemin6
gem (nuclear organelle) associated protein 6
chr4_-_116994374 2.133 ENSMUST00000030446.8
Urod
uroporphyrinogen decarboxylase
chr8_-_107439585 2.117 ENSMUST00000077208.4
Rps26-ps1
ribosomal protein S26, pseudogene 1
chr14_+_52110939 2.114 ENSMUST00000111600.4
Rpgrip1
retinitis pigmentosa GTPase regulator interacting protein 1
chr5_+_107900502 2.104 ENSMUST00000082223.6
Rpl5
ribosomal protein L5
chr11_+_114668524 2.102 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
Rpl38



ribosomal protein L38



chr7_-_101903783 2.098 ENSMUST00000106969.1
Tomt
transmembrane O-methyltransferase
chr5_-_4758216 2.083 ENSMUST00000054294.4
Fzd1
frizzled homolog 1 (Drosophila)
chr16_-_22265950 2.073 ENSMUST00000161286.1
Tra2b
transformer 2 beta homolog (Drosophila)
chr14_+_63860290 2.068 ENSMUST00000022528.4
Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr11_+_69995777 2.056 ENSMUST00000018716.3
Phf23
PHD finger protein 23
chr3_-_138131356 2.036 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr2_+_172472512 2.035 ENSMUST00000029007.2
Fam209
family with sequence similarity 209
chr19_+_36083696 2.025 ENSMUST00000025714.7
Rpp30
ribonuclease P/MRP 30 subunit
chr4_-_117156144 2.012 ENSMUST00000102696.4
Rps8
ribosomal protein S8
chr14_+_121878591 2.010 ENSMUST00000039803.5
Ubac2
ubiquitin associated domain containing 2
chr15_-_82244716 2.008 ENSMUST00000089155.4
ENSMUST00000089157.3
Cenpm

centromere protein M

chr8_+_95825353 1.998 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr7_-_141475131 1.993 ENSMUST00000043870.8
Polr2l
polymerase (RNA) II (DNA directed) polypeptide L
chr11_-_5152218 1.982 ENSMUST00000163299.1
ENSMUST00000062821.6
Emid1

EMI domain containing 1

chr15_-_5121172 1.977 ENSMUST00000090488.2
Gm10250
predicted pseudogene 10250
chr15_+_76904070 1.972 ENSMUST00000004072.8
Rpl8
ribosomal protein L8
chr11_-_106388066 1.949 ENSMUST00000106813.2
ENSMUST00000141146.1
Icam2

intercellular adhesion molecule 2

chr11_-_116027961 1.940 ENSMUST00000106454.1
H3f3b
H3 histone, family 3B
chr7_-_118116171 1.937 ENSMUST00000131374.1
Rps15a
ribosomal protein S15A
chr7_-_118584669 1.929 ENSMUST00000044195.4
Tmc7
transmembrane channel-like gene family 7
chr10_+_78393298 1.922 ENSMUST00000072739.4
Gm10146
predicted gene 10146
chr12_-_111966954 1.922 ENSMUST00000021719.5
2010107E04Rik
RIKEN cDNA 2010107E04 gene
chr10_-_80406811 1.920 ENSMUST00000020372.5
Uqcr11
ubiquinol-cytochrome c reductase, complex III subunit XI
chr11_-_68973840 1.908 ENSMUST00000038644.4
Rangrf
RAN guanine nucleotide release factor
chr9_+_54950808 1.902 ENSMUST00000172407.1
Psma4
proteasome (prosome, macropain) subunit, alpha type 4
chr9_-_44344159 1.899 ENSMUST00000077353.7
Hmbs
hydroxymethylbilane synthase
chr10_+_62947011 1.895 ENSMUST00000131422.1
Dna2
DNA replication helicase 2 homolog (yeast)
chr11_+_51619731 1.882 ENSMUST00000127405.1
Nhp2
NHP2 ribonucleoprotein
chr8_+_70152754 1.880 ENSMUST00000072500.6
ENSMUST00000164040.1
ENSMUST00000110146.2
ENSMUST00000110143.1
ENSMUST00000110141.2
ENSMUST00000110140.1
2310045N01Rik

Mef2b



RIKEN cDNA 2310045N01 gene

myocyte enhancer factor 2B



chr10_+_128747850 1.872 ENSMUST00000163377.2
Wibg
within bgcn homolog (Drosophila)
chr10_-_40302186 1.863 ENSMUST00000099945.4
Amd1
S-adenosylmethionine decarboxylase 1
chr4_-_116994354 1.861 ENSMUST00000130273.1
Urod
uroporphyrinogen decarboxylase
chr14_+_47472547 1.858 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr14_+_73173825 1.843 ENSMUST00000166875.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr9_-_96478596 1.839 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr4_+_108579445 1.833 ENSMUST00000102744.3
Orc1
origin recognition complex, subunit 1
chr1_+_17727034 1.831 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr18_-_9726670 1.826 ENSMUST00000171339.1
Gm17430
predicted gene, 17430
chr10_-_81266906 1.821 ENSMUST00000046114.4
Mrpl54
mitochondrial ribosomal protein L54
chr11_+_32205411 1.806 ENSMUST00000039601.3
ENSMUST00000149043.1
Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr19_+_33822908 1.800 ENSMUST00000042061.6
Gm5519
predicted pseudogene 5519
chr7_+_27486910 1.798 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr11_-_40695203 1.791 ENSMUST00000101347.3
Mat2b
methionine adenosyltransferase II, beta
chr14_+_20703027 1.785 ENSMUST00000071215.3
Chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr16_+_38562821 1.775 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr7_+_141131268 1.766 ENSMUST00000026568.8
Ptdss2
phosphatidylserine synthase 2
chr16_+_55966275 1.765 ENSMUST00000023269.4
RPL24
60S ribosomal protein L24
chr2_-_30093642 1.762 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr19_+_12846773 1.756 ENSMUST00000164001.1
Gm5244
predicted pseudogene 5244
chrM_+_7005 1.751 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr16_+_32419696 1.750 ENSMUST00000014220.8
ENSMUST00000080316.7
Tctex1d2

Tctex1 domain containing 2

chr13_-_118387224 1.744 ENSMUST00000022245.8
Mrps30
mitochondrial ribosomal protein S30
chr11_-_98625661 1.743 ENSMUST00000104933.1
Gm12355
predicted gene 12355

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0042732 D-xylose metabolic process(GO:0042732)
2.4 7.3 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
2.3 7.0 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
1.7 5.0 GO:0002865 immune response-inhibiting signal transduction(GO:0002765) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
1.5 4.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
1.5 6.1 GO:0006545 glycine biosynthetic process(GO:0006545)
1.4 5.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.4 5.5 GO:0015825 L-serine transport(GO:0015825)
1.4 4.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.3 4.0 GO:0021557 oculomotor nerve development(GO:0021557)
1.3 3.8 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
1.2 3.7 GO:1990523 bone regeneration(GO:1990523)
1.2 3.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.2 3.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.1 3.2 GO:0046294 formaldehyde catabolic process(GO:0046294)
1.0 2.0 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
1.0 3.0 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.9 0.9 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.9 4.6 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.9 2.7 GO:0006597 spermine biosynthetic process(GO:0006597)
0.8 4.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.8 2.4 GO:0045004 DNA replication proofreading(GO:0045004)
0.8 2.3 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.7 2.2 GO:0016598 protein arginylation(GO:0016598)
0.7 2.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.7 0.7 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.7 2.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.7 2.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.7 3.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.7 2.9 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.7 2.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.7 2.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.7 2.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.7 3.4 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.7 6.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.7 2.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.7 3.3 GO:0015705 iodide transport(GO:0015705)
0.7 1.3 GO:0097194 execution phase of apoptosis(GO:0097194)
0.6 3.8 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.6 4.4 GO:0009249 protein lipoylation(GO:0009249)
0.6 3.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 6.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.6 1.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 4.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.6 2.3 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.6 1.2 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.6 1.7 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.6 2.8 GO:0019236 response to pheromone(GO:0019236)
0.6 2.2 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.6 1.7 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.6 1.7 GO:0036292 DNA rewinding(GO:0036292)
0.6 5.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.6 2.8 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.5 2.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.5 3.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.5 12.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.5 3.2 GO:0003383 apical constriction(GO:0003383)
0.5 4.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.5 3.1 GO:0048318 axial mesoderm development(GO:0048318)
0.5 1.5 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.5 1.5 GO:0046061 dATP catabolic process(GO:0046061)
0.5 1.5 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.5 1.9 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.5 1.4 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.5 1.9 GO:0018065 protein-cofactor linkage(GO:0018065)
0.5 2.4 GO:0002339 B cell selection(GO:0002339)
0.5 1.4 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.5 2.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.5 1.8 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.5 3.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.5 1.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.4 1.3 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.4 1.8 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 3.9 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.4 1.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.4 1.7 GO:0010813 neuropeptide catabolic process(GO:0010813) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.4 2.1 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.4 0.8 GO:0014016 neuroblast differentiation(GO:0014016)
0.4 3.2 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.4 2.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.4 1.6 GO:0010815 bradykinin catabolic process(GO:0010815)
0.4 1.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.4 2.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.4 1.5 GO:0006788 heme oxidation(GO:0006788)
0.4 1.1 GO:0007525 somatic muscle development(GO:0007525)
0.4 3.5 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.3 4.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.3 1.7 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.3 1.0 GO:1901355 response to rapamycin(GO:1901355)
0.3 0.7 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.3 1.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.3 3.6 GO:0006228 UTP biosynthetic process(GO:0006228)
0.3 1.6 GO:0090666 telomere assembly(GO:0032202) scaRNA localization to Cajal body(GO:0090666)
0.3 1.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.3 1.9 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.3 1.9 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.3 1.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.3 10.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.3 2.7 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.3 4.9 GO:0016486 peptide hormone processing(GO:0016486)
0.3 1.4 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.3 1.1 GO:0015822 ornithine transport(GO:0015822)
0.3 1.4 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.3 7.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 2.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 1.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 1.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 10.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 1.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.3 1.3 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.3 1.8 GO:0060325 face morphogenesis(GO:0060325)
0.3 2.9 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.3 1.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 1.0 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.3 0.8 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.3 1.3 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.3 1.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 1.5 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.3 2.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.3 0.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.3 0.8 GO:0090646 RNA 5'-end processing(GO:0000966) mitochondrial tRNA processing(GO:0090646)
0.2 2.0 GO:0008343 adult feeding behavior(GO:0008343)
0.2 1.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 1.5 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026)
0.2 1.2 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.2 1.2 GO:0015817 histidine transport(GO:0015817)
0.2 3.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.2 0.7 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 3.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2 1.6 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.2 0.7 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.2 0.5 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.2 0.7 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.2 1.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 3.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 0.6 GO:1904046 seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 2.9 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 2.9 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 1.4 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.2 1.2 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 1.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 2.0 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 1.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 1.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 1.0 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.2 2.7 GO:0046697 decidualization(GO:0046697)
0.2 0.8 GO:0030576 Cajal body organization(GO:0030576)
0.2 1.4 GO:0042148 strand invasion(GO:0042148)
0.2 1.1 GO:0021539 subthalamus development(GO:0021539)
0.2 1.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 0.8 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.2 1.5 GO:0031424 keratinization(GO:0031424)
0.2 2.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 3.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2 0.9 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 1.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 1.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.2 0.5 GO:0036166 phenotypic switching(GO:0036166)
0.2 5.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 0.7 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.2 1.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 0.9 GO:0051155 positive regulation of myotube differentiation(GO:0010831) positive regulation of striated muscle cell differentiation(GO:0051155)
0.2 1.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 1.0 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 0.8 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2 5.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 1.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 0.5 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.2 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 0.5 GO:0036337 Fas signaling pathway(GO:0036337)
0.2 0.9 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 1.2 GO:0006004 fucose metabolic process(GO:0006004)
0.2 1.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 1.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.4 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.9 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 2.1 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.9 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 3.3 GO:0006825 copper ion transport(GO:0006825)
0.1 0.9 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 1.1 GO:0015824 proline transport(GO:0015824)
0.1 0.3 GO:0006566 threonine metabolic process(GO:0006566)
0.1 1.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 8.5 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 1.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 1.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 2.0 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.1 0.5 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 1.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 1.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 3.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.4 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 1.0 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.8 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.1 0.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.6 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 1.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.0 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.3 GO:0070836 caveola assembly(GO:0070836)
0.1 1.1 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.7 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 3.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.9 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 3.3 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.9 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.1 0.4 GO:0035547 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.1 2.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.9 GO:0006983 ER overload response(GO:0006983)
0.1 0.4 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 0.7 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.9 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.9 GO:0036035 osteoclast development(GO:0036035)
0.1 0.8 GO:0060347 heart trabecula formation(GO:0060347)
0.1 1.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 1.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 6.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 1.1 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 1.7 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.1 0.5 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 14.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 1.3 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.1 0.3 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 1.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 5.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.5 GO:0007602 phototransduction(GO:0007602)
0.1 1.2 GO:0042407 cristae formation(GO:0042407)
0.1 0.3 GO:0036233 glycine import(GO:0036233)
0.1 0.7 GO:0055070 copper ion homeostasis(GO:0055070)
0.1 0.3 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.7 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 1.1 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.6 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.8 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 2.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 2.1 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.1 0.3 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 2.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.2 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 1.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 2.7 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 2.0 GO:0042168 heme metabolic process(GO:0042168)
0.1 1.0 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.3 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.1 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 1.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.9 GO:0051601 exocyst localization(GO:0051601)
0.1 3.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.4 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.1 1.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.9 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 0.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 0.7 GO:0021554 optic nerve development(GO:0021554)
0.1 1.4 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 1.3 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.7 GO:0006270 DNA replication initiation(GO:0006270)
0.1 1.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 1.4 GO:0045760 positive regulation of action potential(GO:0045760)
0.1 3.9 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.7 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 4.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 3.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.4 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 1.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 3.0 GO:0009261 purine ribonucleotide catabolic process(GO:0009154) ribonucleotide catabolic process(GO:0009261)
0.1 0.6 GO:0030539 male genitalia development(GO:0030539)
0.1 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 2.2 GO:0007566 embryo implantation(GO:0007566)
0.1 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 1.1 GO:0006301 postreplication repair(GO:0006301)
0.1 0.9 GO:0060009 Sertoli cell development(GO:0060009)
0.1 1.1 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 2.1 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.1 0.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.6 GO:0031297 replication fork processing(GO:0031297)
0.1 1.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.0 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 2.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 1.1 GO:0007398 ectoderm development(GO:0007398)
0.1 1.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 2.4 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 2.4 GO:0048538 thymus development(GO:0048538)
0.1 0.1 GO:0009838 abscission(GO:0009838)
0.1 0.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.5 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 2.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 0.1 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.5 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 5.5 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.7 GO:0048489 synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)
0.0 2.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 2.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.4 GO:0045333 cellular respiration(GO:0045333)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0021915 neural tube development(GO:0021915)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.2 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 3.4 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.2 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:2001256 mitochondrial calcium ion transport(GO:0006851) regulation of store-operated calcium entry(GO:2001256)
0.0 0.7 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.5 GO:0030903 notochord development(GO:0030903)
0.0 1.0 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.8 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 1.7 GO:0009408 response to heat(GO:0009408)
0.0 0.6 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.1 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 1.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 2.6 GO:0031109 microtubule polymerization or depolymerization(GO:0031109)
0.0 0.0 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.5 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.8 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.5 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.3 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 4.2 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.4 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.3 GO:0043039 tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039)
0.0 0.6 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0048477 oogenesis(GO:0048477)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.0 0.9 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.0 0.2 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.7 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.1 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0 0.2 GO:0015992 proton transport(GO:0015992)
0.0 0.9 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.1 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.4 GO:0043966 histone H3 acetylation(GO:0043966)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.1 8.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.0 3.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.9 1.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.8 5.9 GO:0001940 male pronucleus(GO:0001940)
0.8 8.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.8 4.7 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.7 2.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.7 2.2 GO:0000814 ESCRT II complex(GO:0000814)
0.7 2.7 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.7 11.1 GO:0005652 nuclear lamina(GO:0005652)
0.6 2.5 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.6 1.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.6 3.5 GO:1990393 3M complex(GO:1990393)
0.6 2.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.6 1.7 GO:1990047 spindle matrix(GO:1990047)
0.6 1.1 GO:0061700 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.5 2.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.5 1.6 GO:0000811 GINS complex(GO:0000811)
0.5 1.5 GO:0071914 prominosome(GO:0071914)
0.5 2.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.5 2.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.5 6.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.5 1.9 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.5 1.8 GO:0032021 NELF complex(GO:0032021)
0.4 1.3 GO:0000801 central element(GO:0000801)
0.4 1.8 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.4 3.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.4 4.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.4 3.2 GO:0033269 internode region of axon(GO:0033269)
0.4 3.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.4 5.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.4 28.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 2.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 1.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.4 1.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 2.9 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4 6.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 3.8 GO:0005688 U6 snRNP(GO:0005688)
0.3 2.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.3 3.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.3 17.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 1.3 GO:0070552 BRISC complex(GO:0070552)
0.3 1.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.3 4.2 GO:0000974 Prp19 complex(GO:0000974)
0.3 1.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.3 1.5 GO:0001533 cornified envelope(GO:0001533)
0.3 1.7 GO:0033010 paranodal junction(GO:0033010)
0.3 1.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 5.2 GO:0031527 filopodium membrane(GO:0031527)
0.3 1.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 3.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 3.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 3.8 GO:0031105 septin complex(GO:0031105)
0.2 3.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 1.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.9 GO:0001520 outer dense fiber(GO:0001520)
0.2 3.7 GO:0031528 microvillus membrane(GO:0031528)
0.2 10.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 0.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 2.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 1.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 1.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 3.1 GO:0070469 respiratory chain(GO:0070469)
0.2 1.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2 0.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 0.6 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.2 2.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 0.9 GO:0000235 astral microtubule(GO:0000235)
0.2 2.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 0.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 0.6 GO:0014802 terminal cisterna(GO:0014802)
0.2 3.2 GO:0005686 U2 snRNP(GO:0005686)
0.2 0.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 2.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 3.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 13.2 GO:0005643 nuclear pore(GO:0005643)
0.2 0.8 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.4 GO:0036157 outer dynein arm(GO:0036157)
0.2 0.6 GO:0005745 m-AAA complex(GO:0005745)
0.1 1.5 GO:0032009 early phagosome(GO:0032009)
0.1 4.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.0 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 0.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.6 GO:0030891 VCB complex(GO:0030891)
0.1 2.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.0 GO:0097255 R2TP complex(GO:0097255)
0.1 1.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.7 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 2.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.2 GO:0061617 MICOS complex(GO:0061617)
0.1 0.9 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.6 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 1.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.4 GO:0009986 cell surface(GO:0009986)
0.1 10.8 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 1.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.7 GO:0043218 compact myelin(GO:0043218)
0.1 1.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.9 GO:0031415 NatA complex(GO:0031415)
0.1 3.5 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 1.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 2.1 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.7 GO:0070187 telosome(GO:0070187)
0.1 0.4 GO:1902636 kinociliary basal body(GO:1902636)
0.1 2.6 GO:0036126 sperm flagellum(GO:0036126)
0.1 1.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 4.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.4 GO:0030894 replisome(GO:0030894) nuclear replisome(GO:0043601)
0.1 1.8 GO:0031514 motile cilium(GO:0031514)
0.1 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.5 GO:0090543 Flemming body(GO:0090543)
0.1 6.2 GO:0005581 collagen trimer(GO:0005581)
0.1 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 3.5 GO:0005840 ribosome(GO:0005840)
0.1 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 3.3 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.2 GO:0070069 cytochrome complex(GO:0070069)
0.1 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.7 GO:0030686 90S preribosome(GO:0030686)
0.1 2.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 3.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.8 GO:0046930 pore complex(GO:0046930)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 2.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.0 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.6 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 1.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.4 GO:0030914 STAGA complex(GO:0030914)
0.1 3.7 GO:0005882 intermediate filament(GO:0005882)
0.1 2.5 GO:0097546 ciliary base(GO:0097546)
0.1 1.6 GO:0005921 gap junction(GO:0005921)
0.1 1.3 GO:0071564 npBAF complex(GO:0071564)
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.1 1.4 GO:0001741 XY body(GO:0001741)
0.1 1.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 3.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 2.7 GO:0005871 kinesin complex(GO:0005871)
0.1 0.9 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.4 GO:0032590 dendrite membrane(GO:0032590)
0.1 2.5 GO:0005902 microvillus(GO:0005902)
0.1 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 4.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0036452 ESCRT complex(GO:0036452)
0.0 1.4 GO:0005903 brush border(GO:0005903)
0.0 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 13.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 7.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0000502 proteasome complex(GO:0000502)
0.0 3.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 1.9 GO:0014704 intercalated disc(GO:0014704)
0.0 2.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.9 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 8.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.9 GO:0000776 kinetochore(GO:0000776)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 37.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.1 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.4 GO:0097223 sperm part(GO:0097223)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
2.3 11.4 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
2.0 6.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.5 4.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
1.4 7.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.3 5.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.2 4.9 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
1.1 3.2 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
1.0 3.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.9 3.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.8 5.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.8 4.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.8 3.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.8 2.5 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.8 2.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.8 2.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.8 4.8 GO:0042731 PH domain binding(GO:0042731)
0.8 3.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.8 2.3 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.8 3.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.8 2.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.8 4.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.7 2.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.7 2.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.7 2.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.7 2.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.7 4.7 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.7 2.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.6 0.6 GO:0008641 ubiquitin activating enzyme activity(GO:0004839) small protein activating enzyme activity(GO:0008641)
0.6 2.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.6 4.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.6 8.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6 1.7 GO:0051870 methotrexate binding(GO:0051870)
0.6 8.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6 1.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.5 4.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.5 2.6 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.5 5.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.5 1.5 GO:0071723 lipopeptide binding(GO:0071723)
0.5 6.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 2.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.5 5.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.5 1.9 GO:0019808 polyamine binding(GO:0019808)
0.5 1.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.4 3.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.4 1.7 GO:0030984 kininogen binding(GO:0030984)
0.4 2.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.4 1.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.4 1.2 GO:0030172 troponin C binding(GO:0030172)
0.4 0.8 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.4 8.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 3.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.4 1.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.4 6.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.4 6.3 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.4 11.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 1.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.4 1.1 GO:0034618 arginine binding(GO:0034618)
0.4 1.4 GO:0035877 death effector domain binding(GO:0035877)
0.4 3.5 GO:0015266 protein channel activity(GO:0015266)
0.4 4.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 3.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 4.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 3.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 1.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.3 7.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 1.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 0.6 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.3 4.7 GO:0016805 dipeptidase activity(GO:0016805)
0.3 2.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 2.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.3 1.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3 1.2 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.3 1.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.3 1.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.3 1.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 1.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 1.1 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.3 45.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 0.8 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.3 1.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 2.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 5.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 2.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.2 2.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 0.7 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.2 6.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 0.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 2.5 GO:0008430 selenium binding(GO:0008430)
0.2 1.1 GO:0008097 5S rRNA binding(GO:0008097)
0.2 1.4 GO:0000150 recombinase activity(GO:0000150)
0.2 1.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 3.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 0.7 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.2 1.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 2.1 GO:0008301 DNA binding, bending(GO:0008301)
0.2 0.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 0.8 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.2 3.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 2.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 4.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 1.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 5.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.2 1.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 2.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.0 GO:0016531 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531) copper-dependent protein binding(GO:0032767)
0.2 1.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 0.8 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.2 3.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 1.1 GO:0004497 monooxygenase activity(GO:0004497)
0.2 0.6 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 2.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 1.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 0.9 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 3.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 0.8 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2 1.0 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 0.7 GO:0050436 microfibril binding(GO:0050436)
0.2 0.5 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 2.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.8 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 1.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 4.3 GO:0008198 ferrous iron binding(GO:0008198)
0.2 4.0 GO:0008432 JUN kinase binding(GO:0008432)
0.2 1.7 GO:0036310 annealing helicase activity(GO:0036310)
0.2 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 1.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.4 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 0.6 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 0.3 GO:0070905 serine binding(GO:0070905)
0.1 0.4 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 1.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 2.1 GO:0005537 mannose binding(GO:0005537)
0.1 1.6 GO:0070402 NADPH binding(GO:0070402)
0.1 0.5 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.1 0.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.8 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 3.6 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 5.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)
0.1 0.4 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.1 0.5 GO:0036435 deubiquitinase activator activity(GO:0035800) K48-linked polyubiquitin binding(GO:0036435)
0.1 2.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 2.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 3.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 3.6 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 1.2 GO:1990405 protein antigen binding(GO:1990405)
0.1 0.8 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.1 3.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 2.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.4 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 1.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.8 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 1.9 GO:0005109 frizzled binding(GO:0005109)
0.1 0.6 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 2.4 GO:0016504 peptidase activator activity(GO:0016504)
0.1 1.4 GO:0051400 BH domain binding(GO:0051400)
0.1 1.6 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 1.0 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 1.3 GO:0016594 glycine binding(GO:0016594)
0.1 1.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.7 GO:0005112 Notch binding(GO:0005112)
0.1 1.7 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 1.3 GO:0001848 complement binding(GO:0001848)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 1.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 3.2 GO:0070888 E-box binding(GO:0070888)
0.1 1.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 3.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 3.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 2.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 2.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.0 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.4 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1 1.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 4.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 1.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 1.5 GO:0002039 p53 binding(GO:0002039)
0.1 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 0.6 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.2 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.1 0.1 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.1 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.7 GO:0005507 copper ion binding(GO:0005507)
0.1 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.9 GO:0017166 vinculin binding(GO:0017166)
0.1 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 4.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 2.3 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.6 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 6.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0 1.2 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.2 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.9 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 2.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.9 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 8.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.1 GO:0020037 heme binding(GO:0020037)
0.0 0.5 GO:0017069 snRNA binding(GO:0017069)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.7 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 6.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 1.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.0 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0016835 carbon-oxygen lyase activity(GO:0016835)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.3 GO:0042393 histone binding(GO:0042393)
0.0 5.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.0 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4 10.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.3 13.1 PID_ATR_PATHWAY ATR signaling pathway
0.2 7.0 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.2 1.8 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 5.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 6.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 2.6 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 1.5 PID_ALK2_PATHWAY ALK2 signaling events
0.1 3.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 3.6 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.1 2.6 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.1 13.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 4.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 2.1 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 1.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 3.9 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 0.8 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.5 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 1.2 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.1 2.2 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 1.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 9.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.8 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 2.4 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 2.9 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 3.3 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.3 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.4 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.9 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 1.1 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.4 PID_BMP_PATHWAY BMP receptor signaling
0.0 2.0 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 2.4 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 1.1 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.5 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.1 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID_NCADHERIN_PATHWAY N-cadherin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 1.7 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.5 8.5 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.4 26.8 REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.4 8.0 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.4 40.2 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.4 8.1 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.3 5.0 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.3 0.9 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 2.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.3 6.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 4.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 2.2 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 3.8 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 2.5 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 4.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 6.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 3.8 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 6.1 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 15.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.2 2.5 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 4.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.2 4.7 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.2 1.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 5.5 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.2 2.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 13.6 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 1.7 REACTOME_LIPOPROTEIN_METABOLISM Genes involved in Lipoprotein metabolism
0.2 1.5 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.2 5.1 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.2 2.3 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 4.0 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.0 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.3 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 0.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 7.5 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 4.4 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 4.0 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.5 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 0.6 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 3.0 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.6 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 1.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 5.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.3 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.6 REACTOME_TRNA_AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 4.3 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 2.8 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.1 7.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.0 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.3 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 3.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.4 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.6 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 0.6 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 2.7 REACTOME_TRANSLATION Genes involved in Translation
0.0 1.5 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.0 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.2 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.4 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.8 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.9 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.8 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM Genes involved in Integration of energy metabolism
0.0 0.4 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 2.7 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.2 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 1.0 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.7 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.5 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME_METABOLISM_OF_CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions