Motif ID: Pou1f1

Z-value: 0.607


Transcription factors associated with Pou1f1:

Gene SymbolEntrez IDGene Name
Pou1f1 ENSMUSG00000004842.12 Pou1f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou1f1mm10_v2_chr16_+_65520503_65520548-0.029.5e-01Click!


Activity profile for motif Pou1f1.

activity profile for motif Pou1f1


Sorted Z-values histogram for motif Pou1f1

Sorted Z-values for motif Pou1f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou1f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 1.719 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr10_+_26229707 0.630 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr5_+_106609098 0.628 ENSMUST00000167618.1
 Gm17304
predicted gene, 17304
chr2_-_169587745 0.579 ENSMUST00000109160.2
 Gm11011
predicted gene 11011
chr2_-_67433181 0.576 ENSMUST00000180773.1
 Gm26727
predicted gene, 26727
chr9_+_34904913 0.503 ENSMUST00000045091.6
 Kirrel3
kin of IRRE like 3 (Drosophila)
chr5_+_73006897 0.498 ENSMUST00000031127.7
 Slc10a4
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr12_-_20900867 0.485 ENSMUST00000079237.5
 Zfp125
zinc finger protein 125
chr13_+_76579670 0.451 ENSMUST00000126960.1
ENSMUST00000109583.2
 Mctp1

multiple C2 domains, transmembrane 1

chr7_+_82611777 0.448 ENSMUST00000172784.1
 Adamtsl3
ADAMTS-like 3
chr17_+_21690766 0.431 ENSMUST00000097384.1
 Gm10509
predicted gene 10509
chr17_+_17316078 0.428 ENSMUST00000105311.3
 Gm6712
predicted gene 6712
chr4_-_97183166 0.427 ENSMUST00000086672.2
 Gm10192
predicted gene 10192
chr7_-_28008416 0.427 ENSMUST00000180024.1
 Zfp850
zinc finger protein 850
chr13_-_14523178 0.415 ENSMUST00000110516.2
 Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr10_-_109009055 0.388 ENSMUST00000156979.1
 Syt1
synaptotagmin I
chr6_-_113719880 0.381 ENSMUST00000064993.5
 Ghrl
ghrelin
chr17_+_16972910 0.378 ENSMUST00000071374.5
 BC002059
cDNA sequence BC002059
chr13_-_62607499 0.376 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr2_+_163225363 0.342 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.0 GO:0015671 oxygen transport(GO:0015671)
0.0 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.5 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.3 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 0.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.2 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.2 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.1 0.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.1 GO:1990047 spindle matrix(GO:1990047)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.3 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 0.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.4 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.3 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha