Motif ID: Pou2f1

Z-value: 0.856


Transcription factors associated with Pou2f1:

Gene SymbolEntrez IDGene Name
Pou2f1 ENSMUSG00000026565.12 Pou2f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou2f1mm10_v2_chr1_-_166002591_166002609-0.662.7e-03Click!


Activity profile for motif Pou2f1.

activity profile for motif Pou2f1


Sorted Z-values histogram for motif Pou2f1

Sorted Z-values for motif Pou2f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_26229707 2.738 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr1_+_45311538 1.780 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr11_+_84525669 1.242 ENSMUST00000126072.1
ENSMUST00000128121.1
 1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr11_+_84525647 1.132 ENSMUST00000134800.1
 1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr15_+_94629148 1.073 ENSMUST00000080141.4
 Tmem117
transmembrane protein 117
chr12_-_108003594 1.057 ENSMUST00000066060.4
 Bcl11b
B cell leukemia/lymphoma 11B
chr5_+_137553517 0.978 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
 Actl6b




actin-like 6B




chr4_+_13751297 0.896 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_133688978 0.852 ENSMUST00000149154.1
ENSMUST00000167944.1
 Pcdh19

protocadherin 19

chr11_+_58948890 0.838 ENSMUST00000078267.3
 Hist3h2ba
histone cluster 3, H2ba
chr7_+_24507006 0.832 ENSMUST00000176880.1
 Zfp428
zinc finger protein 428
chr9_+_91368970 0.812 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chrX_+_42526585 0.774 ENSMUST00000101619.3
 Gm10483
predicted gene 10483
chr9_+_91368811 0.770 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr4_+_85205120 0.759 ENSMUST00000107188.3
 Sh3gl2
SH3-domain GRB2-like 2
chr13_+_23571382 0.729 ENSMUST00000079251.5
 Hist1h2bg
histone cluster 1, H2bg
chr4_-_132533488 0.723 ENSMUST00000152993.1
ENSMUST00000067496.6
 Atpif1

ATPase inhibitory factor 1

chr13_-_23574196 0.721 ENSMUST00000105106.1
 Hist1h2bf
histone cluster 1, H2bf
chr1_-_138856819 0.649 ENSMUST00000112025.1
 2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr2_+_144599897 0.646 ENSMUST00000028917.6
 Dtd1
D-tyrosyl-tRNA deacylase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0006334 nucleosome assembly(GO:0006334)
0.0 2.3 GO:0006342 chromatin silencing(GO:0006342)
0.4 1.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.1 1.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 1.0 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.2 0.8 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.8 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.8 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.7 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2 0.6 GO:0072284 cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.6 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.6 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 0.5 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.1 0.5 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.4 GO:1900141 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142)
0.1 0.4 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.1 1.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.0 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.7 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.6 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.4 GO:0070569 pyrimidine ribonucleotide binding(GO:0032557) uridylyltransferase activity(GO:0070569)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in C2:CP category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.6 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.3 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.3 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.1 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes