Motif ID: Pou2f3

Z-value: 0.861


Transcription factors associated with Pou2f3:

Gene SymbolEntrez IDGene Name
Pou2f3 ENSMUSG00000032015.9 Pou2f3



Activity profile for motif Pou2f3.

activity profile for motif Pou2f3


Sorted Z-values histogram for motif Pou2f3

Sorted Z-values for motif Pou2f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_53845086 6.807 ENSMUST00000108014.1
 Gm10985
predicted gene 10985
chr1_-_166002613 1.861 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
 Pou2f1



POU domain, class 2, transcription factor 1



chr5_-_109558957 1.330 ENSMUST00000044579.7
 Crlf2
cytokine receptor-like factor 2
chr4_+_101986626 0.983 ENSMUST00000106914.1
 Gm12789
predicted gene 12789
chr15_+_92597104 0.979 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr9_-_89092835 0.921 ENSMUST00000167113.1
 Trim43b
tripartite motif-containing 43B
chr19_+_40659770 0.862 ENSMUST00000112231.2
ENSMUST00000127828.1
 Entpd1

ectonucleoside triphosphate diphosphohydrolase 1

chr7_-_42578588 0.788 ENSMUST00000179470.1
 Gm21028
predicted gene, 21028
chr2_-_72986716 0.759 ENSMUST00000112062.1
 Gm11084
predicted gene 11084
chr8_+_129118043 0.718 ENSMUST00000108744.1
 1700008F21Rik
RIKEN cDNA 1700008F21 gene
chr1_-_166002591 0.698 ENSMUST00000111429.4
ENSMUST00000176800.1
 Pou2f1

POU domain, class 2, transcription factor 1

chr12_+_118846329 0.697 ENSMUST00000063918.2
 Sp8
trans-acting transcription factor 8
chr14_+_26122609 0.694 ENSMUST00000100810.6
 Duxbl2
doubl homeobox B-like 2
chr17_-_31636631 0.679 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
 Cbs


cystathionine beta-synthase


chr9_+_13431361 0.647 ENSMUST00000071254.6
 Phxr4
per-hexamer repeat gene 4
chr7_-_99980431 0.612 ENSMUST00000080817.4
 Rnf169
ring finger protein 169
chrX_-_23266751 0.608 ENSMUST00000115316.2
 Klhl13
kelch-like 13
chr14_-_100149764 0.596 ENSMUST00000097079.4
 Klf12
Kruppel-like factor 12
chr12_+_38780284 0.592 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr7_-_49636847 0.589 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 1.3 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.1 0.9 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 0.7 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.0 0.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 0.6 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.6 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.1 0.5 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.5 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.5 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.5 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.4 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.9 GO:0005605 basal lamina(GO:0005605)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.4 GO:0005940 septin ring(GO:0005940)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.3 GO:0070820 tertiary granule(GO:0070820)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.2 GO:0071920 cleavage body(GO:0071920)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.9 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.2 0.7 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.4 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.4 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.2 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.6 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.5 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.2 PID_IL27_PATHWAY IL27-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.9 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition