Motif ID: Pou3f2

Z-value: 0.539


Transcription factors associated with Pou3f2:

Gene SymbolEntrez IDGene Name
Pou3f2 ENSMUSG00000095139.1 Pou3f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f2mm10_v2_chr4_-_22488296_224883660.465.6e-02Click!


Activity profile for motif Pou3f2.

activity profile for motif Pou3f2


Sorted Z-values histogram for motif Pou3f2

Sorted Z-values for motif Pou3f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou3f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 112 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_5593566 1.987 ENSMUST00000160910.1
 Zeb1
zinc finger E-box binding homeobox 1
chr1_+_74661794 1.528 ENSMUST00000129890.1
 Ttll4
tubulin tyrosine ligase-like family, member 4
chr5_-_148392810 1.225 ENSMUST00000138257.1
 Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr11_+_23256566 1.201 ENSMUST00000136235.1
 Xpo1
exportin 1, CRM1 homolog (yeast)
chr17_-_6449571 1.119 ENSMUST00000180035.1
 Tmem181b-ps
transmembrane protein 181B, pseudogene
chr2_+_65930117 1.046 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chrX_-_145505175 1.043 ENSMUST00000143610.1
 Amot
angiomotin
chr3_+_88965812 0.976 ENSMUST00000090933.4
 Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr6_+_90465287 0.931 ENSMUST00000113530.1
 Klf15
Kruppel-like factor 15
chrX_-_165004829 0.897 ENSMUST00000114890.2
 Gm17604
predicted gene, 17604
chr14_-_103843685 0.876 ENSMUST00000172237.1
 Ednrb
endothelin receptor type B
chr14_+_32166104 0.808 ENSMUST00000164341.1
 Ncoa4
nuclear receptor coactivator 4
chr7_+_75610038 0.803 ENSMUST00000125771.1
 Akap13
A kinase (PRKA) anchor protein 13
chr14_-_103844173 0.758 ENSMUST00000022718.3
 Ednrb
endothelin receptor type B
chr13_-_74376566 0.750 ENSMUST00000091481.2
 Zfp72
zinc finger protein 72
chr16_+_36875119 0.731 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
 Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr4_-_110286581 0.693 ENSMUST00000138972.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_+_74661714 0.686 ENSMUST00000042125.8
ENSMUST00000141119.1
 Ttll4

tubulin tyrosine ligase-like family, member 4

chr1_+_34121250 0.682 ENSMUST00000183006.1
 Dst
dystonin
chr15_-_83149270 0.661 ENSMUST00000129372.1
 Poldip3
polymerase (DNA-directed), delta interacting protein 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 2.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.5 1.6 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.3 1.3 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 1.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.2 GO:0015809 arginine transport(GO:0015809)
0.2 1.0 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 1.0 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.9 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.8 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.8 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.7 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.6 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0044754 autolysosome(GO:0044754)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.0 GO:0005915 zonula adherens(GO:0005915)
0.1 0.9 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.8 GO:0000346 transcription export complex(GO:0000346)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.2 0.7 GO:0031673 H zone(GO:0031673)
0.0 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0042581 specific granule(GO:0042581)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.5 1.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 1.3 GO:0043532 angiostatin binding(GO:0043532)
0.2 1.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 1.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.6 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.2 0.5 GO:0042936 dipeptide transporter activity(GO:0042936)
0.2 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.1 0.4 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)

Gene overrepresentation in C2:CP category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 2.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 1.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.7 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 1.4 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.0 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.1 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac