Motif ID: Pou4f3

Z-value: 0.502


Transcription factors associated with Pou4f3:

Gene SymbolEntrez IDGene Name
Pou4f3 ENSMUSG00000024497.3 Pou4f3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou4f3mm10_v2_chr18_+_42394539_42394575-0.106.9e-01Click!


Activity profile for motif Pou4f3.

activity profile for motif Pou4f3


Sorted Z-values histogram for motif Pou4f3

Sorted Z-values for motif Pou4f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou4f3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_58499398 1.937 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1
chr10_+_37139558 1.873 ENSMUST00000062667.3
 5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr10_-_37138863 1.462 ENSMUST00000092584.5
 Marcks
myristoylated alanine rich protein kinase C substrate
chr11_+_117809687 1.158 ENSMUST00000120928.1
ENSMUST00000175737.1
 Syngr2

synaptogyrin 2

chr18_+_11633276 1.074 ENSMUST00000115861.2
 Rbbp8
retinoblastoma binding protein 8
chr11_+_117809653 1.062 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
 Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr5_+_92809372 1.024 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr17_-_48432723 0.962 ENSMUST00000046549.3
 Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr11_+_114675431 0.814 ENSMUST00000045779.5
 Ttyh2
tweety homolog 2 (Drosophila)
chr10_+_97482350 0.794 ENSMUST00000163448.2
 Dcn
decorin
chr7_-_101837776 0.787 ENSMUST00000165052.1
 Inppl1
inositol polyphosphate phosphatase-like 1
chr13_-_58354862 0.750 ENSMUST00000043605.5
 Kif27
kinesin family member 27
chr3_-_33082004 0.653 ENSMUST00000108225.3
 Pex5l
peroxisomal biogenesis factor 5-like
chr1_+_109983737 0.644 ENSMUST00000172005.1
 Cdh7
cadherin 7, type 2
chr2_+_132847719 0.632 ENSMUST00000124836.1
ENSMUST00000154160.1
 Crls1

cardiolipin synthase 1

chr4_+_63558748 0.491 ENSMUST00000077709.4
 6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr13_-_56296551 0.458 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr1_-_89933290 0.446 ENSMUST00000036954.7
 Gbx2
gastrulation brain homeobox 2
chr10_+_102158858 0.439 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
 Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr17_+_6978860 0.408 ENSMUST00000089119.5
ENSMUST00000179728.1
 Rnaset2b

ribonuclease T2B

chr5_-_3647806 0.393 ENSMUST00000119783.1
ENSMUST00000007559.8
 Gatad1

GATA zinc finger domain containing 1

chr2_+_109917639 0.344 ENSMUST00000046548.7
ENSMUST00000111037.2
 Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr14_+_58893465 0.342 ENSMUST00000079960.1
 Rpl13-ps3
ribosomal protein L13, pseudogene 3
chrX_+_9885622 0.337 ENSMUST00000067529.2
ENSMUST00000086165.3
 Sytl5

synaptotagmin-like 5

chr9_+_110132015 0.326 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
 Smarcc1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1




chr9_+_123366921 0.280 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr14_+_69347587 0.265 ENSMUST00000064831.5
 Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr7_-_38019505 0.251 ENSMUST00000085513.4
 Uri1
URI1, prefoldin-like chaperone
chr2_-_140671400 0.246 ENSMUST00000056760.3
 Flrt3
fibronectin leucine rich transmembrane protein 3
chr5_-_117287583 0.218 ENSMUST00000111973.1
ENSMUST00000036951.6
 Pebp1

phosphatidylethanolamine binding protein 1

chr15_+_79690869 0.218 ENSMUST00000046463.8
 Gtpbp1
GTP binding protein 1
chr5_-_43981757 0.211 ENSMUST00000061299.7
 Fgfbp1
fibroblast growth factor binding protein 1
chr18_+_56562443 0.205 ENSMUST00000130163.1
ENSMUST00000132628.1
 Phax

phosphorylated adaptor for RNA export

chr7_+_35802593 0.196 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr6_-_24528013 0.177 ENSMUST00000023851.5
 Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr1_+_194619815 0.162 ENSMUST00000027952.5
 Plxna2
plexin A2
chr10_-_76110956 0.144 ENSMUST00000120757.1
 Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr1_+_45795485 0.135 ENSMUST00000147308.1
 Wdr75
WD repeat domain 75
chr10_-_63927434 0.123 ENSMUST00000079279.3
 Gm10118
predicted gene 10118
chr7_-_138909492 0.110 ENSMUST00000106112.1
 Bnip3
BCL2/adenovirus E1B interacting protein 3
chr7_-_99980431 0.100 ENSMUST00000080817.4
 Rnf169
ring finger protein 169
chr5_-_38491948 0.096 ENSMUST00000129099.1
 Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr2_-_160619971 0.077 ENSMUST00000109473.1
 Gm14221
predicted gene 14221
chr12_-_82496537 0.056 ENSMUST00000179295.1
 Gm5435
predicted gene 5435
chr5_-_69590783 0.030 ENSMUST00000173927.1
 Gnpda2
glucosamine-6-phosphate deaminase 2
chr7_-_46672537 0.014 ENSMUST00000049298.7
 Tph1
tryptophan hydroxylase 1
chr5_-_120612558 0.011 ENSMUST00000140554.1
ENSMUST00000031599.2
ENSMUST00000177800.1
 1110008J03Rik


RIKEN cDNA 1110008J03 gene


chr9_+_110052016 0.009 ENSMUST00000164930.1
ENSMUST00000163979.1
 Map4

microtubule-associated protein 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 1.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.2 0.5 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 0.3 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.7 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.6 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 0.4 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 1.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) response to cobalt ion(GO:0032025) mitochondrial protein catabolic process(GO:0035694)
0.0 0.8 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 1.0 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0042585 germinal vesicle(GO:0042585)
0.2 0.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.3 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.8 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 2.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 1.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.8 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.8 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.5 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.9 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 0.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.9 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation