Motif ID: Ppara
Z-value: 2.347
Transcription factors associated with Ppara:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Ppara | ENSMUSG00000022383.7 | Ppara |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 11.4 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 2.6 | 7.9 | GO:0099548 | drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548) |
| 2.4 | 7.3 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
| 2.3 | 6.9 | GO:0032430 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
| 2.0 | 8.1 | GO:0060083 | smooth muscle contraction involved in micturition(GO:0060083) |
| 2.0 | 5.9 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
| 1.9 | 5.8 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
| 1.7 | 6.8 | GO:0098884 | postsynaptic neurotransmitter receptor internalization(GO:0098884) |
| 1.3 | 3.9 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
| 1.2 | 5.0 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
| 1.2 | 11.2 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 1.2 | 4.9 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 1.2 | 4.7 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
| 1.1 | 3.4 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
| 1.1 | 3.2 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
| 1.1 | 3.2 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 1.1 | 3.2 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 1.0 | 4.9 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 1.0 | 1.0 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
| 0.9 | 2.7 | GO:1901228 | regulation of osteoclast proliferation(GO:0090289) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) negative regulation of bone development(GO:1903011) |
| 0.9 | 7.9 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.8 | 5.4 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.7 | 2.2 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.7 | 3.7 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.7 | 5.2 | GO:0030242 | pexophagy(GO:0030242) |
| 0.7 | 2.2 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.7 | 8.5 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
| 0.7 | 3.3 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
| 0.7 | 2.0 | GO:0010871 | negative regulation of receptor biosynthetic process(GO:0010871) |
| 0.7 | 1.3 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.6 | 1.9 | GO:0061763 | multivesicular body-lysosome fusion(GO:0061763) |
| 0.6 | 1.9 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
| 0.6 | 2.5 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.6 | 1.9 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 0.6 | 5.3 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.6 | 1.8 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.6 | 3.5 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
| 0.6 | 4.0 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.6 | 2.3 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.6 | 2.8 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
| 0.6 | 2.3 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.5 | 2.1 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
| 0.5 | 1.6 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 0.5 | 1.6 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) |
| 0.5 | 4.1 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.5 | 1.5 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.5 | 3.5 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
| 0.5 | 2.5 | GO:0070460 | thyroid-stimulating hormone secretion(GO:0070460) |
| 0.5 | 1.5 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 0.5 | 4.4 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.5 | 12.2 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
| 0.5 | 2.9 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.5 | 1.4 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.5 | 9.4 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.5 | 6.5 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
| 0.5 | 2.3 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.5 | 1.4 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.4 | 3.9 | GO:0098937 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 0.4 | 2.1 | GO:0055095 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 0.4 | 3.4 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.4 | 0.4 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
| 0.4 | 2.1 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.4 | 10.8 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.4 | 3.7 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.4 | 2.0 | GO:0015817 | glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365) |
| 0.4 | 0.4 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.4 | 6.3 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.4 | 2.0 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.4 | 5.9 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 0.4 | 1.9 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
| 0.4 | 2.7 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.4 | 3.0 | GO:0071472 | cellular response to salt stress(GO:0071472) |
| 0.4 | 1.5 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.4 | 1.9 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.4 | 2.3 | GO:0046103 | ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103) |
| 0.4 | 3.7 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.4 | 15.3 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.4 | 1.5 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 0.4 | 1.1 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.3 | 1.0 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
| 0.3 | 1.4 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.3 | 2.4 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
| 0.3 | 12.0 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
| 0.3 | 2.0 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.3 | 2.0 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.3 | 1.3 | GO:2000546 | positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546) |
| 0.3 | 2.6 | GO:1900244 | positive regulation of synaptic vesicle endocytosis(GO:1900244) |
| 0.3 | 6.4 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.3 | 2.2 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
| 0.3 | 0.9 | GO:0035672 | regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672) |
| 0.3 | 0.9 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.3 | 5.0 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.3 | 0.9 | GO:0043181 | vacuolar sequestering(GO:0043181) |
| 0.3 | 6.0 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.3 | 0.9 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.3 | 1.5 | GO:1903181 | regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) |
| 0.3 | 2.6 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.3 | 1.4 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.3 | 2.0 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.3 | 1.7 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.3 | 1.4 | GO:1902947 | regulation of tau-protein kinase activity(GO:1902947) |
| 0.3 | 2.1 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.3 | 2.1 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
| 0.3 | 0.8 | GO:0038027 | apolipoprotein A-I-mediated signaling pathway(GO:0038027) |
| 0.3 | 0.8 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
| 0.3 | 2.1 | GO:0098707 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.3 | 0.8 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
| 0.3 | 1.5 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.3 | 0.8 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 0.3 | 3.3 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.3 | 4.8 | GO:0099645 | protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645) |
| 0.2 | 1.5 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.2 | 6.2 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.2 | 6.9 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.2 | 0.9 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.2 | 1.6 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.2 | 2.0 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) lipid glycosylation(GO:0030259) |
| 0.2 | 3.1 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
| 0.2 | 4.9 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.2 | 2.7 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.2 | 1.3 | GO:1903351 | response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) |
| 0.2 | 2.8 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 0.2 | 0.6 | GO:0048377 | neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) positive regulation of cardiac ventricle development(GO:1904414) |
| 0.2 | 2.7 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.2 | 0.8 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
| 0.2 | 0.4 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
| 0.2 | 1.4 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.2 | 3.6 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 0.2 | 3.8 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.2 | 12.2 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
| 0.2 | 0.6 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.2 | 1.2 | GO:0036394 | amylase secretion(GO:0036394) |
| 0.2 | 1.0 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.2 | 1.0 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.2 | 0.4 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.2 | 2.0 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.2 | 0.4 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
| 0.2 | 10.5 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.2 | 0.5 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.2 | 3.3 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
| 0.2 | 1.4 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 0.2 | 0.5 | GO:0035523 | protein K29-linked deubiquitination(GO:0035523) |
| 0.2 | 0.5 | GO:0070375 | ERK5 cascade(GO:0070375) |
| 0.2 | 1.3 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.2 | 1.5 | GO:0015802 | basic amino acid transport(GO:0015802) arginine transport(GO:0015809) |
| 0.2 | 1.8 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.2 | 1.6 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
| 0.2 | 1.0 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.2 | 0.8 | GO:0030641 | regulation of cellular pH(GO:0030641) |
| 0.2 | 1.2 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.2 | 0.6 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 0.1 | 2.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.4 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) |
| 0.1 | 2.2 | GO:0051895 | negative regulation of focal adhesion assembly(GO:0051895) |
| 0.1 | 0.8 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.1 | 1.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.1 | 0.4 | GO:0036118 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 0.1 | 2.3 | GO:0021819 | layer formation in cerebral cortex(GO:0021819) |
| 0.1 | 0.7 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.1 | 0.4 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation(GO:0033138) |
| 0.1 | 0.9 | GO:0051004 | plasma membrane to endosome transport(GO:0048227) regulation of lipoprotein lipase activity(GO:0051004) |
| 0.1 | 2.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 2.5 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
| 0.1 | 0.6 | GO:0006538 | glutamate catabolic process(GO:0006538) |
| 0.1 | 0.5 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 0.1 | 0.5 | GO:0035630 | bone mineralization involved in bone maturation(GO:0035630) |
| 0.1 | 0.5 | GO:0097494 | regulation of vesicle size(GO:0097494) |
| 0.1 | 0.4 | GO:0060003 | copper ion export(GO:0060003) cellular response to manganese ion(GO:0071287) |
| 0.1 | 0.8 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.1 | 0.6 | GO:0070627 | ferrous iron import(GO:0070627) |
| 0.1 | 2.0 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 0.6 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.1 | 0.9 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
| 0.1 | 1.2 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 0.1 | 1.5 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 0.8 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 4.1 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
| 0.1 | 2.9 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 1.0 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
| 0.1 | 2.0 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.1 | 1.0 | GO:1900194 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 0.6 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.1 | 0.5 | GO:0034115 | negative regulation of heterotypic cell-cell adhesion(GO:0034115) cell-cell adhesion involved in gastrulation(GO:0070586) regulation of cell-cell adhesion involved in gastrulation(GO:0070587) negative regulation of protein kinase C signaling(GO:0090038) |
| 0.1 | 4.8 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.1 | 1.2 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.1 | 0.4 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.1 | 1.5 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 1.2 | GO:0048520 | positive regulation of behavior(GO:0048520) |
| 0.1 | 0.3 | GO:0003289 | atrial septum primum morphogenesis(GO:0003289) |
| 0.1 | 0.5 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.1 | 0.4 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 0.1 | 0.8 | GO:1901162 | serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162) |
| 0.1 | 1.4 | GO:0007183 | SMAD protein complex assembly(GO:0007183) |
| 0.1 | 1.7 | GO:0007271 | synaptic transmission, cholinergic(GO:0007271) |
| 0.1 | 0.3 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 1.1 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.1 | 0.3 | GO:0070844 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.1 | 3.3 | GO:0035249 | synaptic transmission, glutamatergic(GO:0035249) |
| 0.1 | 0.5 | GO:0071435 | potassium ion export(GO:0071435) |
| 0.1 | 0.6 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.1 | 1.6 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 2.1 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.1 | 0.3 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.1 | 3.3 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.1 | 0.5 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.1 | 1.1 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.1 | 2.2 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.1 | 2.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 11.9 | GO:0030041 | actin filament polymerization(GO:0030041) |
| 0.1 | 1.0 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 3.1 | GO:0060997 | dendritic spine morphogenesis(GO:0060997) |
| 0.1 | 0.6 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
| 0.1 | 1.1 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 0.3 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.1 | 1.0 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 0.2 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.1 | 0.4 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
| 0.1 | 0.1 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 0.1 | 0.4 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.1 | 1.0 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 1.3 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.1 | 0.5 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.1 | 0.2 | GO:0051792 | medium-chain fatty acid biosynthetic process(GO:0051792) |
| 0.1 | 0.5 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.1 | 13.1 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.1 | 1.1 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.1 | 1.1 | GO:0015858 | nucleoside transport(GO:0015858) |
| 0.1 | 3.3 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.1 | 0.4 | GO:0015879 | carnitine transport(GO:0015879) |
| 0.1 | 0.8 | GO:2000273 | positive regulation of receptor activity(GO:2000273) |
| 0.1 | 0.8 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.1 | 0.3 | GO:0051665 | membrane raft localization(GO:0051665) |
| 0.1 | 0.2 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.1 | 0.4 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 0.1 | 0.6 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.1 | 1.1 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
| 0.1 | 5.7 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.1 | 1.3 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
| 0.1 | 4.0 | GO:0030010 | establishment of cell polarity(GO:0030010) |
| 0.0 | 0.4 | GO:2000232 | regulation of rRNA processing(GO:2000232) |
| 0.0 | 0.5 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.0 | 0.3 | GO:1901387 | positive regulation of voltage-gated calcium channel activity(GO:1901387) |
| 0.0 | 0.7 | GO:0001964 | startle response(GO:0001964) |
| 0.0 | 0.2 | GO:0032148 | activation of protein kinase B activity(GO:0032148) |
| 0.0 | 0.3 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
| 0.0 | 0.4 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.0 | 0.3 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.0 | 0.6 | GO:0098780 | response to mitochondrial depolarisation(GO:0098780) |
| 0.0 | 1.6 | GO:0031641 | regulation of myelination(GO:0031641) |
| 0.0 | 0.3 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.0 | 0.5 | GO:0097484 | dendrite extension(GO:0097484) |
| 0.0 | 0.8 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 1.1 | GO:1904377 | positive regulation of protein localization to cell periphery(GO:1904377) |
| 0.0 | 0.9 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.0 | 2.1 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.3 | GO:0000022 | mitotic spindle elongation(GO:0000022) spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256) |
| 0.0 | 0.4 | GO:0072348 | sulfur compound transport(GO:0072348) |
| 0.0 | 0.5 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 1.5 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.0 | 0.3 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.0 | 0.4 | GO:0018195 | peptidyl-arginine modification(GO:0018195) |
| 0.0 | 1.4 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
| 0.0 | 1.8 | GO:0009062 | fatty acid catabolic process(GO:0009062) |
| 0.0 | 1.9 | GO:0050806 | positive regulation of synaptic transmission(GO:0050806) |
| 0.0 | 0.2 | GO:1903020 | positive regulation of glycoprotein metabolic process(GO:1903020) |
| 0.0 | 0.4 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 0.0 | 0.1 | GO:1901857 | positive regulation of cellular respiration(GO:1901857) |
| 0.0 | 1.0 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.0 | 0.1 | GO:0015744 | succinate transport(GO:0015744) |
| 0.0 | 0.1 | GO:0030238 | male sex determination(GO:0030238) |
| 0.0 | 2.4 | GO:0007286 | spermatid development(GO:0007286) |
| 0.0 | 0.9 | GO:0010824 | regulation of centrosome duplication(GO:0010824) |
| 0.0 | 0.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.0 | 0.3 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.0 | 0.2 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.0 | 0.6 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.0 | 1.5 | GO:0030534 | adult behavior(GO:0030534) |
| 0.0 | 0.2 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.0 | 0.2 | GO:0072329 | monocarboxylic acid catabolic process(GO:0072329) |
| 0.0 | 0.1 | GO:1903527 | regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527) |
| 0.0 | 1.4 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.8 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.0 | 0.0 | GO:0060281 | regulation of oocyte development(GO:0060281) |
| 0.0 | 1.1 | GO:0000045 | autophagosome assembly(GO:0000045) |
| 0.0 | 0.5 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.0 | 0.3 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.1 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.3 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 0.5 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.0 | 0.1 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.0 | 0.2 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.0 | 0.3 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.0 | 0.3 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.5 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) |
| 0.0 | 0.2 | GO:0048536 | spleen development(GO:0048536) |
| 0.0 | 0.0 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
| 0.0 | 0.2 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.0 | 0.3 | GO:0000422 | mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726) |
| 0.0 | 0.3 | GO:0016239 | positive regulation of macroautophagy(GO:0016239) |
| 0.0 | 0.4 | GO:0001707 | mesoderm formation(GO:0001707) |
| 0.0 | 0.2 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
| 0.0 | 0.9 | GO:0045667 | regulation of osteoblast differentiation(GO:0045667) |
| 0.0 | 0.6 | GO:0042073 | intraciliary transport(GO:0042073) |
| 0.0 | 0.4 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.2 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 7.3 | GO:0072534 | perineuronal net(GO:0072534) |
| 1.7 | 6.8 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 1.2 | 5.8 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 1.1 | 9.9 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 1.1 | 9.8 | GO:0097427 | microtubule bundle(GO:0097427) |
| 1.0 | 3.9 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.9 | 4.7 | GO:0044316 | cone cell pedicle(GO:0044316) |
| 0.9 | 2.8 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.9 | 6.4 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.8 | 11.3 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.7 | 3.6 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.7 | 7.9 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.7 | 6.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.5 | 1.6 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 0.5 | 1.5 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.5 | 9.4 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.5 | 4.1 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.5 | 0.9 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.4 | 4.0 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.4 | 8.8 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.4 | 2.1 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.4 | 4.0 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.4 | 10.2 | GO:0031430 | M band(GO:0031430) |
| 0.4 | 1.9 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 0.3 | 3.0 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.3 | 1.0 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.3 | 12.1 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.3 | 2.6 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.3 | 2.3 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.3 | 1.4 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.3 | 5.9 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.3 | 2.1 | GO:0097433 | dense body(GO:0097433) |
| 0.3 | 22.8 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.2 | 7.1 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.2 | 3.2 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.2 | 5.5 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.2 | 0.8 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.2 | 1.9 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.2 | 1.0 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.2 | 3.6 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.2 | 3.5 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 1.8 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.2 | 0.7 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.2 | 1.4 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.2 | 2.4 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.2 | 3.0 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.2 | 0.8 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.2 | 19.8 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.1 | 3.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 3.0 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.1 | 0.5 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.1 | 0.6 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 6.0 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 21.6 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 1.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 2.2 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 0.4 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
| 0.1 | 1.1 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.1 | 1.1 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 2.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 0.6 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.1 | 0.4 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.1 | 3.4 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.1 | 0.5 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.1 | 0.9 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.1 | 1.0 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 2.1 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.1 | 4.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 4.4 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 0.8 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.1 | 2.4 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 13.1 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 2.1 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 4.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.1 | 1.0 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 0.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 10.5 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.1 | 0.9 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 0.7 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 0.7 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 0.3 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.1 | 0.5 | GO:0097413 | Lewy body(GO:0097413) |
| 0.1 | 2.6 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.1 | 5.0 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.1 | 1.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 0.8 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 7.9 | GO:0031252 | cell leading edge(GO:0031252) |
| 0.0 | 8.0 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 8.8 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 0.7 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 0.0 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.0 | 3.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.1 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 0.5 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 0.4 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 2.8 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.9 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 2.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.3 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 1.6 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 10.5 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 0.6 | GO:0005901 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.0 | 0.8 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 9.8 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.0 | 1.6 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.4 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.7 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.0 | 0.3 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.0 | 1.1 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.6 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.4 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 0.1 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 0.8 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.0 | 0.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 1.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.3 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.3 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.7 | GO:0005604 | basement membrane(GO:0005604) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 7.9 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 2.4 | 7.3 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
| 2.3 | 6.8 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) |
| 1.9 | 11.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 1.4 | 4.1 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 1.3 | 5.3 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 1.0 | 18.0 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 1.0 | 5.8 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.9 | 3.7 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.9 | 5.4 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.8 | 2.5 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.8 | 4.9 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.8 | 3.3 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 0.8 | 4.0 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.7 | 2.2 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 0.7 | 2.2 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.7 | 2.8 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.7 | 2.0 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.7 | 2.0 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.7 | 2.0 | GO:0015182 | L-asparagine transmembrane transporter activity(GO:0015182) |
| 0.7 | 7.9 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.6 | 6.4 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 0.6 | 2.4 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.6 | 1.8 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.6 | 7.2 | GO:0050897 | cobalt ion binding(GO:0050897) |
| 0.5 | 2.1 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.5 | 1.5 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.5 | 2.0 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.5 | 1.5 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.5 | 3.5 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.5 | 1.5 | GO:0019966 | interleukin-1 binding(GO:0019966) tumor necrosis factor binding(GO:0043120) |
| 0.5 | 2.9 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.5 | 1.9 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.5 | 4.3 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.5 | 3.2 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
| 0.4 | 8.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.4 | 1.3 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.4 | 3.0 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.4 | 2.1 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.4 | 5.9 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.4 | 17.1 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.4 | 2.1 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.4 | 2.1 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.4 | 2.3 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.4 | 14.4 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.4 | 2.5 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.4 | 10.8 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.4 | 2.1 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.4 | 2.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.4 | 6.0 | GO:0004890 | GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917) |
| 0.4 | 1.4 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.4 | 3.9 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.3 | 1.4 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
| 0.3 | 3.0 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.3 | 1.9 | GO:0019841 | retinol binding(GO:0019841) |
| 0.3 | 0.9 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.3 | 0.9 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.3 | 2.1 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.3 | 2.7 | GO:0036122 | BMP binding(GO:0036122) |
| 0.3 | 8.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.3 | 1.2 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.3 | 3.8 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.3 | 15.2 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.3 | 1.4 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
| 0.3 | 1.1 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.3 | 6.3 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.3 | 4.3 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.3 | 0.8 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 0.3 | 0.8 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
| 0.3 | 5.0 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.2 | 1.9 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.2 | 1.0 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.2 | 6.9 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.2 | 3.0 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.2 | 3.7 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.2 | 3.9 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.2 | 3.9 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.2 | 1.6 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 5.1 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.2 | 2.3 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.2 | 0.8 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
| 0.2 | 2.2 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 0.2 | 1.5 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.2 | 1.0 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.2 | 1.5 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 0.2 | 1.1 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 1.5 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.2 | 0.9 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.2 | 8.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.2 | 0.9 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.2 | 3.9 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 0.5 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.2 | 9.8 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.2 | 0.7 | GO:0004103 | choline kinase activity(GO:0004103) |
| 0.2 | 3.8 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.2 | 0.8 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
| 0.2 | 1.1 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.2 | 1.6 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.2 | 3.1 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.2 | 1.0 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.2 | 1.6 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.2 | 0.8 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.2 | 2.1 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.2 | 2.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.2 | 2.0 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.2 | 1.2 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.2 | 2.1 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 3.5 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.1 | 4.7 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.1 | 1.1 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.1 | 0.4 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
| 0.1 | 1.9 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.1 | 3.0 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 0.4 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.1 | 0.4 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
| 0.1 | 0.8 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
| 0.1 | 4.6 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.4 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.1 | 1.2 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.1 | 1.2 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.1 | 0.6 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.1 | 2.2 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 5.3 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 0.4 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
| 0.1 | 0.4 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.1 | 0.6 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.1 | 0.8 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.1 | 2.6 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
| 0.1 | 2.5 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 0.5 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.1 | 0.4 | GO:0030375 | thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.1 | 0.3 | GO:0004473 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.1 | 1.3 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.1 | 0.6 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 0.1 | 1.4 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.1 | 0.6 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.1 | 2.0 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.1 | 0.3 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.1 | 1.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 2.0 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.1 | 1.4 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
| 0.1 | 0.5 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.1 | 0.7 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.1 | 1.0 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 2.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 2.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.6 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.1 | 1.0 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 0.6 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.1 | 0.4 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
| 0.1 | 2.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 1.1 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 0.3 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
| 0.1 | 1.0 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 1.4 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 0.3 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.1 | 2.0 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.1 | 0.5 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 1.4 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.1 | 3.8 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.1 | 1.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 0.3 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.1 | 2.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 6.9 | GO:0016247 | channel regulator activity(GO:0016247) |
| 0.1 | 1.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 5.4 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 0.5 | GO:0015464 | acetylcholine receptor activity(GO:0015464) acetylcholine-gated cation channel activity(GO:0022848) |
| 0.1 | 2.6 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 19.7 | GO:0003779 | actin binding(GO:0003779) |
| 0.1 | 9.3 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.1 | 5.8 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.1 | 0.3 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.1 | 0.2 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 0.0 | 0.7 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.3 | GO:0002135 | CTP binding(GO:0002135) sulfonylurea receptor binding(GO:0017098) |
| 0.0 | 0.5 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.2 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.0 | 1.0 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 2.1 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.9 | GO:0005496 | steroid binding(GO:0005496) |
| 0.0 | 0.3 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 1.1 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.4 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.0 | 0.5 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.0 | 1.1 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 2.1 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.3 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.0 | 1.0 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 4.4 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.0 | 0.3 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 0.7 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.0 | 1.3 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 1.8 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 0.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 1.4 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.0 | 0.5 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 0.1 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
| 0.0 | 0.7 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 0.6 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 0.6 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 0.0 | 1.1 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.1 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.0 | 0.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.7 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.5 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.5 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.0 | 0.9 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.0 | 0.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.4 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 0.7 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 1.8 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 2.2 | GO:0008514 | organic anion transmembrane transporter activity(GO:0008514) |
| 0.0 | 4.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.5 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.2 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.0 | 3.1 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 1.1 | GO:0016879 | ligase activity, forming carbon-nitrogen bonds(GO:0016879) |
| 0.0 | 0.5 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.1 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 1.8 | GO:0051020 | GTPase binding(GO:0051020) |
| 0.0 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.9 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 0.3 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.1 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
| 0.0 | 0.5 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 5.4 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.2 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.0 | 1.7 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.0 | 0.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 1.4 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.4 | 8.8 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.3 | 2.3 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.2 | 3.9 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.2 | 9.1 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
| 0.2 | 2.2 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
| 0.2 | 2.9 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.2 | 3.4 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.2 | 11.9 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
| 0.2 | 5.8 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.2 | 1.3 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.1 | 2.2 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 16.1 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 5.2 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
| 0.1 | 2.2 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 1.9 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.1 | 4.0 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.1 | 3.8 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 2.1 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 2.6 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.1 | 1.9 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.1 | 7.5 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 1.0 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.1 | 2.0 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.1 | 1.2 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.1 | 1.3 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 3.1 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.5 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 2.1 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
| 0.0 | 1.4 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.0 | 0.7 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.4 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 1.9 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.4 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.9 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.0 | 2.0 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.6 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.0 | 0.9 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.0 | 0.9 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.1 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 11.3 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.6 | 18.3 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.5 | 14.3 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.5 | 6.6 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.5 | 3.7 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.4 | 3.9 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.4 | 5.5 | REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.3 | 8.7 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.3 | 3.7 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.3 | 3.8 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
| 0.3 | 8.6 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.3 | 0.8 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.3 | 3.2 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.3 | 1.3 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.2 | 2.2 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.2 | 25.3 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.2 | 9.4 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.2 | 1.3 | REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
| 0.2 | 3.5 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.2 | 7.5 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.2 | 4.2 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.2 | 1.4 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.2 | 2.2 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.2 | 2.0 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.2 | 2.2 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 3.4 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.1 | 1.5 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 1.7 | REACTOME_COMPLEMENT_CASCADE | Genes involved in Complement cascade |
| 0.1 | 3.5 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 2.9 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 2.0 | REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.1 | 1.5 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 3.0 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 2.1 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 2.0 | REACTOME_SHC_MEDIATED_SIGNALLING | Genes involved in SHC-mediated signalling |
| 0.1 | 2.0 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 2.3 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 2.4 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 0.4 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 0.5 | REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 0.5 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.1 | 0.8 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 2.0 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.1 | 3.0 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 2.3 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 0.8 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.1 | 0.8 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.1 | 1.1 | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.1 | 0.3 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.1 | 0.8 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 1.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.1 | 1.0 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 2.3 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 3.3 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.8 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 2.7 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.7 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 1.0 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 0.5 | REACTOME_SIGNALING_BY_ERBB4 | Genes involved in Signaling by ERBB4 |
| 0.0 | 0.4 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.6 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.6 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.6 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 1.4 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.3 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 0.3 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 1.9 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.3 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.0 | 0.9 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.0 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.4 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.4 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.0 | 1.0 | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | Genes involved in Signaling by EGFR in Cancer |
| 0.0 | 0.4 | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 0.4 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.0 | 0.2 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
