Motif ID: Prdm1

Z-value: 0.845


Transcription factors associated with Prdm1:

Gene SymbolEntrez IDGene Name
Prdm1 ENSMUSG00000038151.6 Prdm1



Activity profile for motif Prdm1.

activity profile for motif Prdm1


Sorted Z-values histogram for motif Prdm1

Sorted Z-values for motif Prdm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_43363855 0.856 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr16_+_43364145 0.831 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr1_-_32547293 0.830 ENSMUST00000171322.1
Gm5415
predicted gene 5415
chr8_-_84800024 0.697 ENSMUST00000126806.1
ENSMUST00000076715.6
Nfix

nuclear factor I/X

chr11_-_77894096 0.683 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr3_-_86548268 0.671 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr8_-_84800344 0.657 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr4_-_96591555 0.656 ENSMUST00000055693.8
Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr2_+_154548888 0.647 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr16_+_65520503 0.643 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
Pou1f1


POU domain, class 1, transcription factor 1


chr1_-_156674290 0.629 ENSMUST00000079625.4
Tor3a
torsin family 3, member A
chr1_-_79671966 0.612 ENSMUST00000162342.1
Ap1s3
adaptor-related protein complex AP-1, sigma 3
chr5_+_3343893 0.599 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr18_-_41951187 0.584 ENSMUST00000070949.4
Prelid2
PRELI domain containing 2
chr7_-_5413145 0.580 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr6_+_117168535 0.558 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
Cxcl12


chemokine (C-X-C motif) ligand 12


chr4_-_154636831 0.554 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr11_+_3514861 0.536 ENSMUST00000094469.4
Selm
selenoprotein M
chr2_+_116067213 0.532 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr1_-_56978534 0.528 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 1.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1 1.0 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.8 GO:0016926 protein desumoylation(GO:0016926)
0.2 0.7 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 0.6 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 0.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.6 GO:0044838 cell quiescence(GO:0044838)
0.2 0.5 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.2 0.5 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.5 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.4 GO:0021984 adenohypophysis development(GO:0021984)
0.1 0.4 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.4 GO:0030432 peristalsis(GO:0030432)
0.0 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.4 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.1 GO:0004454 ketohexokinase activity(GO:0004454)
0.0 0.9 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 0.7 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 0.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 0.4 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.3 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 0.3 GO:0000405 bubble DNA binding(GO:0000405)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 0.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation