Motif ID: Ptf1a

Z-value: 0.506


Transcription factors associated with Ptf1a:

Gene SymbolEntrez IDGene Name
Ptf1a ENSMUSG00000026735.2 Ptf1a



Activity profile for motif Ptf1a.

activity profile for motif Ptf1a


Sorted Z-values histogram for motif Ptf1a

Sorted Z-values for motif Ptf1a



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_141214080 0.712 ENSMUST00000026573.5
ENSMUST00000170841.1
 1600016N20Rik

RIKEN cDNA 1600016N20 gene

chr2_+_26973416 0.608 ENSMUST00000014996.7
ENSMUST00000102891.3
 Adamts13

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

chr19_+_7056731 0.569 ENSMUST00000040261.5
 Macrod1
MACRO domain containing 1
chr11_-_93965957 0.475 ENSMUST00000021220.3
 Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr7_-_4532419 0.423 ENSMUST00000094897.4
 Dnaaf3
dynein, axonemal assembly factor 3
chr11_-_6444352 0.412 ENSMUST00000093346.5
ENSMUST00000109737.2
 H2afv

H2A histone family, member V

chr5_+_64970069 0.396 ENSMUST00000031080.8
 Fam114a1
family with sequence similarity 114, member A1
chr7_-_140102367 0.394 ENSMUST00000142105.1
 Fuom
fucose mutarotase
chr11_+_78324200 0.377 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr10_+_127501672 0.359 ENSMUST00000160019.1
ENSMUST00000160610.1
 Stac3

SH3 and cysteine rich domain 3

chr4_-_155010984 0.358 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
 Plch2


phospholipase C, eta 2


chr10_+_127501707 0.312 ENSMUST00000035839.2
 Stac3
SH3 and cysteine rich domain 3
chr9_-_108305941 0.284 ENSMUST00000044725.7
 Tcta
T cell leukemia translocation altered gene
chr15_-_98004695 0.282 ENSMUST00000023123.8
 Col2a1
collagen, type II, alpha 1
chr11_+_120633719 0.281 ENSMUST00000181502.1
 Gm17586
predicted gene, 17586
chr9_-_21852603 0.278 ENSMUST00000034728.7
 Dock6
dedicator of cytokinesis 6
chr11_-_96916448 0.276 ENSMUST00000103152.4
 Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr9_+_106477269 0.263 ENSMUST00000047721.8
 Rrp9
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr1_+_20951666 0.259 ENSMUST00000038447.4
 Efhc1
EF-hand domain (C-terminal) containing 1
chr8_-_13890233 0.252 ENSMUST00000033839.7
 Coprs
coordinator of PRMT5, differentiation stimulator
chr8_+_94857450 0.245 ENSMUST00000109521.3
 Polr2c
polymerase (RNA) II (DNA directed) polypeptide C
chr15_-_98004634 0.233 ENSMUST00000131560.1
ENSMUST00000088355.5
 Col2a1

collagen, type II, alpha 1

chr10_+_90829538 0.211 ENSMUST00000179694.2
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr12_+_112760652 0.210 ENSMUST00000063888.3
 Pld4
phospholipase D family, member 4
chr1_+_36691487 0.210 ENSMUST00000081180.4
 Cox5b
cytochrome c oxidase subunit Vb
chr11_+_40733936 0.208 ENSMUST00000127382.1
 Nudcd2
NudC domain containing 2
chr11_-_102185202 0.191 ENSMUST00000107156.2
 Lsm12
LSM12 homolog (S. cerevisiae)
chr11_+_40733639 0.190 ENSMUST00000020578.4
 Nudcd2
NudC domain containing 2
chr2_-_91950386 0.190 ENSMUST00000111303.1
 Dgkz
diacylglycerol kinase zeta
chr11_+_48800357 0.189 ENSMUST00000020640.7
 Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr10_-_126901315 0.187 ENSMUST00000026504.5
ENSMUST00000168520.1
 Xrcc6bp1

XRCC6 binding protein 1

chr9_+_123021315 0.182 ENSMUST00000084733.5
 Tmem42
transmembrane protein 42
chr11_-_100440928 0.179 ENSMUST00000107397.1
 Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr11_-_100441006 0.173 ENSMUST00000092689.2
 Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr5_-_99252839 0.172 ENSMUST00000168092.1
ENSMUST00000031276.8
 Rasgef1b

RasGEF domain family, member 1B

chr14_+_75845093 0.171 ENSMUST00000110894.2
 Tpt1
tumor protein, translationally-controlled 1
chr7_-_144582392 0.163 ENSMUST00000033394.7
 Fadd
Fas (TNFRSF6)-associated via death domain
chr14_-_70207637 0.156 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr11_-_100441058 0.154 ENSMUST00000107399.2
ENSMUST00000092688.5
 Nt5c3b

5'-nucleotidase, cytosolic IIIB

chr1_+_92910805 0.153 ENSMUST00000179711.1
 Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr7_-_79386943 0.151 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chrX_+_101383726 0.147 ENSMUST00000119190.1
 Gjb1
gap junction protein, beta 1
chr9_-_112187898 0.144 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chrX_+_166238923 0.143 ENSMUST00000060210.7
ENSMUST00000112233.1
 Gpm6b

glycoprotein m6b

chr11_-_96916407 0.143 ENSMUST00000130774.1
 Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr9_-_108597558 0.141 ENSMUST00000006853.5
 P4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr6_+_83078339 0.140 ENSMUST00000165164.2
ENSMUST00000092614.2
 Pcgf1

polycomb group ring finger 1

chr18_+_32377176 0.137 ENSMUST00000091967.5
ENSMUST00000025239.7
 Bin1

bridging integrator 1

chr16_-_55283237 0.135 ENSMUST00000036412.3
 Zpld1
zona pellucida like domain containing 1
chr2_-_7395968 0.134 ENSMUST00000002176.6
 Celf2
CUGBP, Elav-like family member 2
chr6_+_83078606 0.132 ENSMUST00000177177.1
ENSMUST00000176089.1
 Pcgf1

polycomb group ring finger 1

chr10_+_88201158 0.132 ENSMUST00000171151.2
 Ccdc53
coiled-coil domain containing 53
chr4_-_36056726 0.120 ENSMUST00000108124.3
 Lingo2
leucine rich repeat and Ig domain containing 2
chr9_-_112187766 0.119 ENSMUST00000111872.2
ENSMUST00000164754.2
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr3_-_75556759 0.114 ENSMUST00000162138.1
ENSMUST00000029424.5
ENSMUST00000161137.1
 Pdcd10


programmed cell death 10


chr11_-_96916366 0.111 ENSMUST00000144731.1
ENSMUST00000127048.1
 Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr18_+_34331132 0.108 ENSMUST00000072576.3
ENSMUST00000119329.1
 Srp19

signal recognition particle 19

chr14_-_105176860 0.107 ENSMUST00000163545.1
 Rbm26
RNA binding motif protein 26
chr3_+_75557530 0.106 ENSMUST00000161776.1
ENSMUST00000029423.8
 Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr1_+_92910758 0.100 ENSMUST00000027487.8
 Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr14_-_55944536 0.098 ENSMUST00000022834.6
 Cma1
chymase 1, mast cell
chr2_-_131175201 0.095 ENSMUST00000110218.2
 Spef1
sperm flagellar 1
chr19_+_9982694 0.092 ENSMUST00000025563.6
 Fth1
ferritin heavy chain 1
chr11_-_102185239 0.091 ENSMUST00000021297.5
 Lsm12
LSM12 homolog (S. cerevisiae)
chr2_-_175131864 0.090 ENSMUST00000108929.2
 Gm14399
predicted gene 14399
chr11_+_49247462 0.088 ENSMUST00000109194.1
 Mgat1
mannoside acetylglucosaminyltransferase 1
chr3_+_138277489 0.087 ENSMUST00000004232.9
 Adh1
alcohol dehydrogenase 1 (class I)
chr3_-_108445183 0.081 ENSMUST00000090553.5
ENSMUST00000153499.1
 Sars

seryl-aminoacyl-tRNA synthetase

chr4_+_152096719 0.080 ENSMUST00000105661.3
ENSMUST00000084115.3
 Plekhg5

pleckstrin homology domain containing, family G (with RhoGef domain) member 5

chr18_-_80440850 0.072 ENSMUST00000161003.1
 Ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr11_+_78465697 0.072 ENSMUST00000001126.3
 Slc46a1
solute carrier family 46, member 1
chr2_+_25500750 0.070 ENSMUST00000015239.3
 Fbxw5
F-box and WD-40 domain protein 5
chr11_+_82911253 0.070 ENSMUST00000164945.1
ENSMUST00000018989.7
 Unc45b

unc-45 homolog B (C. elegans)

chr4_-_64046925 0.067 ENSMUST00000107377.3
 Tnc
tenascin C
chr11_-_103344651 0.062 ENSMUST00000041385.7
 Arhgap27
Rho GTPase activating protein 27
chr17_+_7925990 0.061 ENSMUST00000036370.7
 Tagap
T cell activation Rho GTPase activating protein
chr15_-_79774408 0.059 ENSMUST00000023055.6
 Dnal4
dynein, axonemal, light chain 4
chr15_-_79774383 0.058 ENSMUST00000069877.5
 Dnal4
dynein, axonemal, light chain 4
chr19_+_16435616 0.057 ENSMUST00000025602.2
 Gna14
guanine nucleotide binding protein, alpha 14
chr4_+_155839675 0.055 ENSMUST00000141883.1
 Mxra8
matrix-remodelling associated 8
chr9_-_112234956 0.054 ENSMUST00000162097.1
ENSMUST00000159055.1
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr4_-_88438900 0.050 ENSMUST00000132493.1
ENSMUST00000030221.2
ENSMUST00000151280.1
 Ptplad2


protein tyrosine phosphatase-like A domain containing 2


chr11_+_120762792 0.049 ENSMUST00000105046.2
 Hmga1-rs1
high mobility group AT-hook I, related sequence 1
chr1_-_172329261 0.048 ENSMUST00000062387.2
 Kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr19_-_7241216 0.048 ENSMUST00000025675.9
 Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr6_-_69243445 0.048 ENSMUST00000101325.3
 Igkv4-71
immunoglobulin kappa chain variable 4-71
chr6_-_5256226 0.047 ENSMUST00000125686.1
ENSMUST00000031773.2
 Pon3

paraoxonase 3

chr10_+_42678890 0.046 ENSMUST00000040718.5
 Ostm1
osteopetrosis associated transmembrane protein 1
chr11_+_101325063 0.044 ENSMUST00000041095.7
ENSMUST00000107264.1
 Aoc2

amine oxidase, copper containing 2 (retina-specific)

chr4_+_115088708 0.038 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
 Pdzk1ip1



PDZK1 interacting protein 1



chr12_-_113307912 0.034 ENSMUST00000103418.1
 Ighg2b
immunoglobulin heavy constant gamma 2B
chr5_+_149439706 0.034 ENSMUST00000031667.4
 Tex26
testis expressed 26
chr2_+_164769892 0.029 ENSMUST00000088248.6
ENSMUST00000001439.6
 Ube2c

ubiquitin-conjugating enzyme E2C

chr16_+_43762221 0.029 ENSMUST00000023390.4
 Drd3
dopamine receptor D3
chr15_+_80097866 0.027 ENSMUST00000143928.1
 Syngr1
synaptogyrin 1
chr7_-_127725616 0.025 ENSMUST00000076091.2
 Ctf2
cardiotrophin 2
chr16_+_14562316 0.023 ENSMUST00000129643.1
 A630010A05Rik
RIKEN cDNA A630010A05 gene
chr10_-_75932468 0.021 ENSMUST00000120281.1
ENSMUST00000000924.6
 Mmp11

matrix metallopeptidase 11

chr5_+_114314941 0.015 ENSMUST00000124316.1
ENSMUST00000169347.1
 Myo1h

myosin 1H

chr11_+_86484647 0.012 ENSMUST00000020827.6
 Rnft1
ring finger protein, transmembrane 1
chr10_+_86022189 0.010 ENSMUST00000120344.1
ENSMUST00000117597.1
 Fbxo7

F-box protein 7

chr7_-_79842287 0.007 ENSMUST00000049004.6
 Anpep
alanyl (membrane) aminopeptidase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.5 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.3 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.2 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:1904046 seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.0 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0042806 fucose binding(GO:0042806)
0.1 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.0 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0008131 primary amine oxidase activity(GO:0008131)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions