Motif ID: Rarg

Z-value: 1.035


Transcription factors associated with Rarg:

Gene SymbolEntrez IDGene Name
Rarg ENSMUSG00000001288.8 Rarg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rargmm10_v2_chr15_-_102246439_102246510-0.214.1e-01Click!


Activity profile for motif Rarg.

activity profile for motif Rarg


Sorted Z-values histogram for motif Rarg

Sorted Z-values for motif Rarg



Network of associatons between targets according to the STRING database.



First level regulatory network of Rarg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_31949571 2.421 ENSMUST00000064016.5
 Gpr17
G protein-coupled receptor 17
chr9_+_123366921 2.360 ENSMUST00000038863.7
 Lars2
leucyl-tRNA synthetase, mitochondrial
chr5_-_113015473 2.012 ENSMUST00000065167.4
 Adrbk2
adrenergic receptor kinase, beta 2
chr9_+_56865104 1.965 ENSMUST00000035661.5
 Cspg4
chondroitin sulfate proteoglycan 4
chr16_+_17276337 1.864 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
 Tmem191c


transmembrane protein 191C


chr4_-_155645408 1.862 ENSMUST00000115821.2
 Gm10563
predicted gene 10563
chr16_+_17276291 1.778 ENSMUST00000164950.1
ENSMUST00000159242.1
 Tmem191c

transmembrane protein 191C

chrY_+_818646 1.629 ENSMUST00000115894.1
 Uba1y
ubiquitin-activating enzyme, Chr Y
chr1_-_32547293 1.599 ENSMUST00000171322.1
 Gm5415
predicted gene 5415
chr9_+_44981779 1.405 ENSMUST00000034602.7
 Cd3d
CD3 antigen, delta polypeptide
chr4_-_53159885 1.344 ENSMUST00000030010.3
 Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr19_-_57008187 1.339 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr15_+_25742314 1.225 ENSMUST00000135981.1
 Myo10
myosin X
chr1_-_79858627 1.117 ENSMUST00000027467.4
 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr8_+_40862379 1.111 ENSMUST00000098816.3
ENSMUST00000057784.8
ENSMUST00000141505.1
 Slc7a2


solute carrier family 7 (cationic amino acid transporter, y+ system), member 2


chr12_+_116275386 1.095 ENSMUST00000090195.4
 Gm11027
predicted gene 11027
chr8_+_70501116 1.018 ENSMUST00000127983.1
 Crlf1
cytokine receptor-like factor 1
chr14_+_66635251 0.983 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
 Adra1a


adrenergic receptor, alpha 1a


chr11_+_68432112 0.950 ENSMUST00000021283.7
 Pik3r5
phosphoinositide-3-kinase, regulatory subunit 5, p101
chrX_+_136822781 0.943 ENSMUST00000113085.1
 Plp1
proteolipid protein (myelin) 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 170 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 2.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 2.0 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 1.6 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 1.6 GO:0016926 protein desumoylation(GO:0016926)
0.3 1.4 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 1.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.3 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 1.2 GO:0045143 homologous chromosome segregation(GO:0045143)
0.4 1.1 GO:1902022 L-lysine transport(GO:1902022)
0.3 1.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.3 1.0 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.2 1.0 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 0.9 GO:0016056 photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 0.9 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.9 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 1.1 GO:0044307 dendritic branch(GO:0044307)
0.1 1.1 GO:0031091 platelet alpha granule(GO:0031091)
0.1 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 1.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 1.0 GO:0031430 M band(GO:0031430)
0.2 0.9 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.9 GO:0031225 anchored component of membrane(GO:0031225)
0.2 0.8 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 0.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.7 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.7 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.0 0.6 GO:0043196 varicosity(GO:0043196)
0.0 0.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.6 GO:0032590 dendrite membrane(GO:0032590)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 123 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 1.9 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 1.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.8 GO:0005518 collagen binding(GO:0005518)
0.3 1.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.4 1.3 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 1.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.3 1.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 1.0 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.2 1.0 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 1.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.0 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.2 0.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.0 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.0 1.7 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.1 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 0.9 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.7 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.6 PID_MYC_PATHWAY C-MYC pathway
0.0 0.6 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID_S1P_S1P3_PATHWAY S1P3 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 2.4 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.0 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 1.4 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.1 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.9 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.9 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.1 0.7 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.6 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 0.5 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels