Motif ID: Rbpj

Z-value: 0.791


Transcription factors associated with Rbpj:

Gene SymbolEntrez IDGene Name
Rbpj ENSMUSG00000039191.6 Rbpj

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rbpjmm10_v2_chr5_+_53590215_535903510.799.0e-05Click!


Activity profile for motif Rbpj.

activity profile for motif Rbpj


Sorted Z-values histogram for motif Rbpj

Sorted Z-values for motif Rbpj



Network of associatons between targets according to the STRING database.



First level regulatory network of Rbpj

PNG image of the network

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Top targets:


Showing 1 to 20 of 168 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_78324200 1.508 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr10_-_30842765 1.458 ENSMUST00000019924.8
Hey2
hairy/enhancer-of-split related with YRPW motif 2
chr2_-_54085542 1.052 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr4_-_126202335 1.020 ENSMUST00000142125.1
ENSMUST00000106141.2
Thrap3

thyroid hormone receptor associated protein 3

chr2_+_105668935 1.006 ENSMUST00000142772.1
Pax6
paired box gene 6
chr15_-_86033777 1.002 ENSMUST00000016172.7
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr2_+_37776229 0.995 ENSMUST00000050372.7
Crb2
crumbs homolog 2 (Drosophila)
chr18_+_34625009 0.986 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr9_+_123478693 0.984 ENSMUST00000026269.2
Limd1
LIM domains containing 1
chr11_-_62457772 0.971 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chr7_+_122159422 0.844 ENSMUST00000033154.6
Plk1
polo-like kinase 1
chrX_-_73966329 0.826 ENSMUST00000114372.2
ENSMUST00000033761.6
Hcfc1

host cell factor C1

chr12_+_83688123 0.811 ENSMUST00000041806.5
Psen1
presenilin 1
chr18_+_34624621 0.795 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr2_+_59612034 0.785 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr11_-_102579461 0.780 ENSMUST00000107081.1
Gm11627
predicted gene 11627
chr7_-_105752193 0.763 ENSMUST00000033184.4
Tpp1
tripeptidyl peptidase I
chr19_+_53140430 0.750 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr4_-_11007635 0.740 ENSMUST00000054776.3
Plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr4_+_8690399 0.721 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.8 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 1.8 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 1.6 GO:0051639 actin filament network formation(GO:0051639)
0.5 1.5 GO:0003195 tricuspid valve formation(GO:0003195)
0.3 1.5 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.2 1.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 1.3 GO:0014028 notochord formation(GO:0014028)
0.1 1.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.3 1.0 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 1.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.9 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.3 0.8 GO:0019046 release from viral latency(GO:0019046)
0.2 0.8 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038)
0.2 0.8 GO:0015871 astrocyte activation involved in immune response(GO:0002265) choline transport(GO:0015871)
0.0 0.8 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.4 0.7 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 0.6 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.6 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.6 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.1 GO:0016592 mediator complex(GO:0016592)
0.0 1.8 GO:0005871 kinesin complex(GO:0005871)
0.2 1.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 1.2 GO:0032127 dense core granule membrane(GO:0032127)
0.1 1.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.0 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 0.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0031258 catenin complex(GO:0016342) lamellipodium membrane(GO:0031258)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.8 GO:0003777 microtubule motor activity(GO:0003777)
0.5 1.5 GO:0035939 microsatellite binding(GO:0035939)
0.3 1.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.5 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.2 GO:0017166 vinculin binding(GO:0017166)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.2 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.0 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 0.8 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.8 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.8 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.6 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)

Gene overrepresentation in C2:CP category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.4 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.4 PID_CDC42_PATHWAY CDC42 signaling events
0.1 1.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.6 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.5 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.1 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.8 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.5 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.5 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.3 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 1.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.8 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules