Motif ID: Rhox11

Z-value: 0.465


Transcription factors associated with Rhox11:

Gene SymbolEntrez IDGene Name
Rhox11 ENSMUSG00000051038.9 Rhox11



Activity profile for motif Rhox11.

activity profile for motif Rhox11


Sorted Z-values histogram for motif Rhox11

Sorted Z-values for motif Rhox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Rhox11

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_139130159 2.318 ENSMUST00000129851.1
 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr5_+_17574268 2.209 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_17574726 1.700 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr12_+_74288735 1.526 ENSMUST00000095617.1
 1700086L19Rik
RIKEN cDNA 1700086L19 gene
chr11_+_29373618 1.294 ENSMUST00000040182.6
ENSMUST00000109477.1
 Ccdc88a

coiled coil domain containing 88A

chr5_+_21186267 1.212 ENSMUST00000036031.8
 Gsap
gamma-secretase activating protein
chr1_-_162866502 1.069 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr5_+_111733924 1.030 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr11_-_30198232 0.932 ENSMUST00000102838.3
 Sptbn1
spectrin beta, non-erythrocytic 1
chr16_+_29579347 0.804 ENSMUST00000038867.6
ENSMUST00000161186.1
 Opa1

optic atrophy 1

chr15_+_8169067 0.794 ENSMUST00000110617.1
 2410089E03Rik
RIKEN cDNA 2410089E03 gene
chr2_-_150362708 0.696 ENSMUST00000051153.5
 3300002I08Rik
RIKEN cDNA 3300002I08 gene
chr8_+_104831572 0.678 ENSMUST00000059449.6
 Ces2b
carboxyesterase 2B
chr15_+_25742314 0.650 ENSMUST00000135981.1
 Myo10
myosin X
chr17_+_79614900 0.646 ENSMUST00000040368.2
 Rmdn2
regulator of microtubule dynamics 2
chr10_+_58394381 0.642 ENSMUST00000105468.1
 Lims1
LIM and senescent cell antigen-like domains 1
chr10_+_58394361 0.642 ENSMUST00000020077.4
 Lims1
LIM and senescent cell antigen-like domains 1
chr16_+_29579331 0.630 ENSMUST00000160597.1
 Opa1
optic atrophy 1
chr9_-_60838200 0.605 ENSMUST00000063858.7
 Gm9869
predicted gene 9869
chr13_+_49653297 0.563 ENSMUST00000021824.7
 Nol8
nucleolar protein 8
chr16_+_23107413 0.521 ENSMUST00000023599.6
ENSMUST00000168891.1
 Eif4a2

eukaryotic translation initiation factor 4A2

chr8_+_72492915 0.520 ENSMUST00000181452.1
 Gm17435
predicted gene, 17435
chr4_+_126556994 0.518 ENSMUST00000147675.1
 Clspn
claspin
chr13_-_3611064 0.498 ENSMUST00000096069.3
 BC016423
cDNA sequence BC016423
chr9_-_20521375 0.479 ENSMUST00000068296.7
ENSMUST00000174462.1
 Zfp266

zinc finger protein 266

chr3_+_156561792 0.468 ENSMUST00000074015.4
 Negr1
neuronal growth regulator 1
chr3_+_68468162 0.401 ENSMUST00000182532.1
 Schip1
schwannomin interacting protein 1
chr7_-_46795661 0.387 ENSMUST00000123725.1
 Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr18_+_62977854 0.385 ENSMUST00000150267.1
 Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr9_-_20644726 0.350 ENSMUST00000148631.1
ENSMUST00000131128.1
ENSMUST00000151861.1
ENSMUST00000131343.1
ENSMUST00000086458.3
 Fbxl12




F-box and leucine-rich repeat protein 12




chr16_+_23107754 0.344 ENSMUST00000077605.5
ENSMUST00000115341.3
 Eif4a2

eukaryotic translation initiation factor 4A2

chr18_-_24709348 0.290 ENSMUST00000067987.1
 Gm9955
predicted gene 9955
chr8_-_105827190 0.264 ENSMUST00000041400.5
 Ranbp10
RAN binding protein 10
chr1_-_175688353 0.258 ENSMUST00000104984.1
 Chml
choroideremia-like
chr5_+_121220191 0.239 ENSMUST00000119892.2
ENSMUST00000042614.6
 Gm15800

predicted gene 15800

chr3_+_90603767 0.236 ENSMUST00000001046.5
ENSMUST00000107330.1
 S100a4

S100 calcium binding protein A4

chr13_+_47043499 0.232 ENSMUST00000037025.8
ENSMUST00000143868.1
 Kdm1b

lysine (K)-specific demethylase 1B

chr9_+_50768228 0.230 ENSMUST00000042391.6
 Fdxacb1
ferredoxin-fold anticodon binding domain containing 1
chr9_-_44713196 0.218 ENSMUST00000144251.1
ENSMUST00000156918.1
 Phldb1

pleckstrin homology-like domain, family B, member 1

chr17_-_57059795 0.212 ENSMUST00000040280.7
 Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr7_-_46795881 0.212 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
 Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr2_+_178118975 0.211 ENSMUST00000108917.1
 Phactr3
phosphatase and actin regulator 3
chr15_+_36179299 0.208 ENSMUST00000047348.3
 Spag1
sperm associated antigen 1
chr6_-_34977999 0.207 ENSMUST00000044387.7
 2010107G12Rik
RIKEN cDNA 2010107G12 gene
chr1_+_87853264 0.206 ENSMUST00000027517.7
 Dgkd
diacylglycerol kinase, delta
chr7_-_28008416 0.205 ENSMUST00000180024.1
 Zfp850
zinc finger protein 850
chr19_-_8818924 0.198 ENSMUST00000153281.1
 Ttc9c
tetratricopeptide repeat domain 9C
chr6_-_106800051 0.189 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
 Crbn


cereblon


chr11_-_97700327 0.175 ENSMUST00000018681.7
 Pcgf2
polycomb group ring finger 2
chr11_+_98741805 0.168 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr19_+_57452900 0.163 ENSMUST00000026073.6
ENSMUST00000026072.3
 Trub1

TruB pseudouridine (psi) synthase homolog 1 (E. coli)

chr5_+_143933059 0.147 ENSMUST00000166847.1
 Rsph10b
radial spoke head 10 homolog B (Chlamydomonas)
chr11_+_70639118 0.139 ENSMUST00000055184.6
ENSMUST00000108551.2
 Gp1ba

glycoprotein 1b, alpha polypeptide

chr7_+_46796088 0.133 ENSMUST00000006774.4
ENSMUST00000165031.1
 Gtf2h1

general transcription factor II H, polypeptide 1

chr2_-_131352857 0.112 ENSMUST00000059372.4
 Rnf24
ring finger protein 24
chr4_+_126556935 0.104 ENSMUST00000048391.8
 Clspn
claspin
chr6_+_128662379 0.084 ENSMUST00000032518.4
 Clec2h
C-type lectin domain family 2, member h
chr15_+_7129557 0.082 ENSMUST00000067190.5
ENSMUST00000164529.1
 Lifr

leukemia inhibitory factor receptor

chr14_-_20496780 0.076 ENSMUST00000022353.3
 Mss51
MSS51 mitochondrial translational activator
chr5_-_114858682 0.066 ENSMUST00000066959.4
 Gm9936
predicted gene 9936
chrX_-_111536325 0.065 ENSMUST00000156639.1
 Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr17_+_25727726 0.062 ENSMUST00000047273.1
 Rpusd1
RNA pseudouridylate synthase domain containing 1
chr14_-_46822232 0.054 ENSMUST00000111817.1
ENSMUST00000079314.5
 Gmfb

glia maturation factor, beta

chr10_-_59951753 0.032 ENSMUST00000020308.3
 Ddit4
DNA-damage-inducible transcript 4
chr18_+_6765171 0.027 ENSMUST00000097680.5
 Rab18
RAB18, member RAS oncogene family
chr9_+_86743616 0.012 ENSMUST00000036426.6
 Prss35
protease, serine, 35
chr7_+_5051515 0.007 ENSMUST00000069324.5
 Zfp580
zinc finger protein 580
chr4_-_119383732 0.004 ENSMUST00000044781.2
ENSMUST00000084307.3
 Ccdc30

coiled-coil domain containing 30


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.4 1.4 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.3 1.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.3 1.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 2.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.1 GO:0070995 toxin metabolic process(GO:0009404) NADPH oxidation(GO:0070995)
0.1 1.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.2 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.6 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 0.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.4 GO:0001553 luteinization(GO:0001553)
0.0 0.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0042730 fibrinolysis(GO:0042730)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 0.9 GO:0032437 cuticular plate(GO:0032437)
0.2 2.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 GO:0038191 neuropilin binding(GO:0038191)
0.2 1.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 1.4 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 1.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 3.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.6 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.9 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.9 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling