Motif ID: Rhox11

Z-value: 0.465


Transcription factors associated with Rhox11:

Gene SymbolEntrez IDGene Name
Rhox11 ENSMUSG00000051038.9 Rhox11



Activity profile for motif Rhox11.

activity profile for motif Rhox11


Sorted Z-values histogram for motif Rhox11

Sorted Z-values for motif Rhox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Rhox11

PNG image of the network

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Top targets:


Showing 1 to 20 of 68 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_139130159 2.318 ENSMUST00000129851.1
 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr5_+_17574268 2.209 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_17574726 1.700 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr12_+_74288735 1.526 ENSMUST00000095617.1
 1700086L19Rik
RIKEN cDNA 1700086L19 gene
chr11_+_29373618 1.294 ENSMUST00000040182.6
ENSMUST00000109477.1
 Ccdc88a

coiled coil domain containing 88A

chr5_+_21186267 1.212 ENSMUST00000036031.8
 Gsap
gamma-secretase activating protein
chr1_-_162866502 1.069 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr5_+_111733924 1.030 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr11_-_30198232 0.932 ENSMUST00000102838.3
 Sptbn1
spectrin beta, non-erythrocytic 1
chr16_+_29579347 0.804 ENSMUST00000038867.6
ENSMUST00000161186.1
 Opa1

optic atrophy 1

chr15_+_8169067 0.794 ENSMUST00000110617.1
 2410089E03Rik
RIKEN cDNA 2410089E03 gene
chr2_-_150362708 0.696 ENSMUST00000051153.5
 3300002I08Rik
RIKEN cDNA 3300002I08 gene
chr8_+_104831572 0.678 ENSMUST00000059449.6
 Ces2b
carboxyesterase 2B
chr15_+_25742314 0.650 ENSMUST00000135981.1
 Myo10
myosin X
chr17_+_79614900 0.646 ENSMUST00000040368.2
 Rmdn2
regulator of microtubule dynamics 2
chr10_+_58394381 0.642 ENSMUST00000105468.1
 Lims1
LIM and senescent cell antigen-like domains 1
chr10_+_58394361 0.642 ENSMUST00000020077.4
 Lims1
LIM and senescent cell antigen-like domains 1
chr16_+_29579331 0.630 ENSMUST00000160597.1
 Opa1
optic atrophy 1
chr9_-_60838200 0.605 ENSMUST00000063858.7
 Gm9869
predicted gene 9869
chr13_+_49653297 0.563 ENSMUST00000021824.7
 Nol8
nucleolar protein 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 3.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.2 2.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.4 1.4 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.3 1.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.3 1.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 1.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 1.1 GO:0070995 toxin metabolic process(GO:0009404) NADPH oxidation(GO:0070995)
0.1 0.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.6 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.4 GO:0001553 luteinization(GO:0001553)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.2 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 1.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.3 GO:0036064 ciliary basal body(GO:0036064)
0.2 0.9 GO:0032437 cuticular plate(GO:0032437)
0.0 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.1 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.9 GO:0038191 neuropilin binding(GO:0038191)
0.2 2.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 1.4 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 1.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.3 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.3 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.7 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.6 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.9 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen