Motif ID: Runx2_Bcl11a

Z-value: 0.987

Transcription factors associated with Runx2_Bcl11a:

Gene SymbolEntrez IDGene Name
Bcl11a ENSMUSG00000000861.9 Bcl11a
Runx2 ENSMUSG00000039153.10 Runx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl11amm10_v2_chr11_+_24078022_240780760.243.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Runx2_Bcl11a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_11008458 2.050 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr1_-_169747634 1.431 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chrX_+_159697308 1.236 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr17_+_88626549 1.225 ENSMUST00000163588.1
ENSMUST00000064035.6
Ston1

stonin 1

chr15_-_66801577 1.190 ENSMUST00000168589.1
Sla
src-like adaptor
chr1_+_165302625 1.119 ENSMUST00000111450.1
Gpr161
G protein-coupled receptor 161
chr10_+_61171954 1.022 ENSMUST00000122261.1
ENSMUST00000121297.1
ENSMUST00000035894.5
Tbata


thymus, brain and testes associated


chr3_-_88000350 0.938 ENSMUST00000090971.5
Bcan
brevican
chr1_+_58210397 0.908 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr9_+_54764748 0.904 ENSMUST00000034830.8
Crabp1
cellular retinoic acid binding protein I
chr11_+_3330781 0.899 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr4_+_133176336 0.881 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr9_-_103219823 0.848 ENSMUST00000168142.1
Trf
transferrin
chr13_+_76579670 0.839 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr17_+_75178797 0.821 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr2_+_31759993 0.789 ENSMUST00000124089.1
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr15_-_100584075 0.761 ENSMUST00000184908.1
POU6F1
POU domain, class 6, transcription factor 1 (Pou6f1), mRNA
chr4_+_48049080 0.744 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr11_+_80183851 0.730 ENSMUST00000017839.2
Rnf135
ring finger protein 135
chr6_-_126645784 0.729 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr7_-_103827922 0.706 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr17_+_75178911 0.697 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr11_+_3330401 0.668 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr11_+_78322965 0.644 ENSMUST00000017534.8
Aldoc
aldolase C, fructose-bisphosphate
chr5_+_37047464 0.642 ENSMUST00000137019.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr11_-_106579111 0.634 ENSMUST00000103070.2
Tex2
testis expressed gene 2
chr15_-_89170688 0.630 ENSMUST00000060808.9
Plxnb2
plexin B2
chr17_+_8849974 0.624 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr11_+_75532127 0.618 ENSMUST00000127226.1
Slc43a2
solute carrier family 43, member 2
chr1_-_38664947 0.611 ENSMUST00000039827.7
ENSMUST00000027250.7
Aff3

AF4/FMR2 family, member 3

chr18_+_32938955 0.610 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chr11_-_116654245 0.602 ENSMUST00000021166.5
Cygb
cytoglobin
chr4_+_144892813 0.591 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr4_-_143299463 0.587 ENSMUST00000119654.1
Pdpn
podoplanin
chr11_-_11970540 0.565 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr5_+_37050854 0.557 ENSMUST00000043794.4
Jakmip1
janus kinase and microtubule interacting protein 1
chr18_+_37496997 0.555 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr6_+_51432663 0.535 ENSMUST00000005103.5
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr14_+_66297029 0.531 ENSMUST00000022623.6
ENSMUST00000121006.1
Trim35

tripartite motif-containing 35

chr7_+_121707189 0.515 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr11_+_75531690 0.514 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr4_-_143299498 0.514 ENSMUST00000030317.7
Pdpn
podoplanin
chr2_+_154436437 0.512 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr10_-_33995054 0.510 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chr4_+_128058962 0.509 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr9_+_83548309 0.498 ENSMUST00000113215.3
Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
chr2_+_153031852 0.492 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr9_+_121642716 0.485 ENSMUST00000035115.4
Vipr1
vasoactive intestinal peptide receptor 1
chr9_+_32224457 0.481 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chrX_+_151344171 0.477 ENSMUST00000073364.5
Fam120c
family with sequence similarity 120, member C
chr2_-_132111440 0.474 ENSMUST00000128899.1
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr7_+_127876796 0.471 ENSMUST00000131000.1
Zfp646
zinc finger protein 646
chr16_+_94370786 0.462 ENSMUST00000147046.1
ENSMUST00000149885.1
ENSMUST00000127667.1
ENSMUST00000119131.1
ENSMUST00000145883.1
Ttc3




tetratricopeptide repeat domain 3




chr19_+_53677286 0.461 ENSMUST00000095969.3
ENSMUST00000164202.1
Rbm20

RNA binding motif protein 20

chrX_-_73966329 0.447 ENSMUST00000114372.2
ENSMUST00000033761.6
Hcfc1

host cell factor C1

chr5_-_98030727 0.447 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr7_-_128596278 0.445 ENSMUST00000179317.1
Gm7258
predicted gene 7258
chr14_+_31641051 0.443 ENSMUST00000090147.6
Btd
biotinidase
chr4_+_136284658 0.437 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr11_-_98329641 0.437 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr1_-_168432270 0.436 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr6_+_55836878 0.429 ENSMUST00000044729.6
Ccdc129
coiled-coil domain containing 129
chr11_+_75532099 0.418 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr17_+_21690766 0.417 ENSMUST00000097384.1
Gm10509
predicted gene 10509
chr10_-_62379852 0.411 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
Hk1



hexokinase 1



chr16_+_16896469 0.407 ENSMUST00000027373.9
Ppm1f
protein phosphatase 1F (PP2C domain containing)
chr11_+_101246960 0.402 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr7_+_49246812 0.401 ENSMUST00000184945.1
Nav2
neuron navigator 2
chr7_-_115824699 0.401 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr5_+_66968961 0.400 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr5_-_53707532 0.398 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chrX_+_93654863 0.396 ENSMUST00000113933.2
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chrX_+_106027300 0.386 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr11_-_6200411 0.380 ENSMUST00000066496.3
Nudcd3
NudC domain containing 3
chr14_-_54686060 0.376 ENSMUST00000125265.1
Acin1
apoptotic chromatin condensation inducer 1
chr16_+_42907563 0.375 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr9_+_120929216 0.373 ENSMUST00000130466.1
Ctnnb1
catenin (cadherin associated protein), beta 1
chr1_-_172027251 0.369 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr5_-_77408034 0.369 ENSMUST00000163898.1
ENSMUST00000046746.6
Igfbp7

insulin-like growth factor binding protein 7

chr15_-_100425050 0.364 ENSMUST00000123461.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr13_-_54687644 0.363 ENSMUST00000129881.1
Rnf44
ring finger protein 44
chr15_+_25758755 0.352 ENSMUST00000131834.1
ENSMUST00000124966.1
Myo10

myosin X

chr16_-_23520579 0.348 ENSMUST00000089883.5
Masp1
mannan-binding lectin serine peptidase 1
chr14_+_55853997 0.348 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr2_+_69897255 0.347 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr2_+_20737306 0.346 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr6_-_87809757 0.346 ENSMUST00000032134.7
Rab43
RAB43, member RAS oncogene family
chr1_-_168431695 0.346 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr5_-_122002340 0.344 ENSMUST00000134326.1
Cux2
cut-like homeobox 2
chr1_-_133131782 0.343 ENSMUST00000180528.1
Gm26616
predicted gene, 26616
chr10_+_19934472 0.340 ENSMUST00000095806.3
ENSMUST00000120259.1
Map3k5

mitogen-activated protein kinase kinase kinase 5

chr5_+_34549595 0.337 ENSMUST00000179943.1
Sh3bp2
SH3-domain binding protein 2
chr15_+_99393574 0.337 ENSMUST00000162624.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr12_-_81333129 0.336 ENSMUST00000085238.6
ENSMUST00000182208.1
Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr7_+_112519612 0.336 ENSMUST00000106640.1
Parva
parvin, alpha
chr3_+_96830069 0.336 ENSMUST00000058865.7
Pdzk1
PDZ domain containing 1
chr5_-_124187150 0.331 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr1_-_195131536 0.331 ENSMUST00000075451.6
Cr1l
complement component (3b/4b) receptor 1-like
chr1_-_190911728 0.331 ENSMUST00000159066.1
ENSMUST00000061611.8
Rps6kc1

ribosomal protein S6 kinase polypeptide 1

chr12_-_110682606 0.330 ENSMUST00000070659.5
1700001K19Rik
RIKEN cDNA 1700001K19 gene
chr7_+_100706623 0.330 ENSMUST00000107042.1
Fam168a
family with sequence similarity 168, member A
chr13_+_55600055 0.327 ENSMUST00000133176.1
ENSMUST00000064701.6
B4galt7

xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)

chr6_-_83572429 0.322 ENSMUST00000068054.7
Stambp
STAM binding protein
chr5_+_121660528 0.322 ENSMUST00000031414.8
Brap
BRCA1 associated protein
chr16_-_85901118 0.321 ENSMUST00000023611.5
Adamts5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
chr11_-_120630516 0.321 ENSMUST00000106181.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr9_-_62510498 0.320 ENSMUST00000164246.2
Coro2b
coronin, actin binding protein, 2B
chr9_+_49518336 0.313 ENSMUST00000068730.3
Gm11149
predicted gene 11149
chr2_+_121357714 0.313 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr7_-_78577771 0.312 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr4_-_32923455 0.311 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr15_+_99393610 0.309 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr5_-_24704656 0.306 ENSMUST00000181925.1
Gm26648
predicted gene, 26648
chr7_-_35754394 0.306 ENSMUST00000051377.8
Dpy19l3
dpy-19-like 3 (C. elegans)
chr15_-_53902472 0.306 ENSMUST00000078673.6
Samd12
sterile alpha motif domain containing 12
chr15_-_102722150 0.305 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr10_+_128805652 0.303 ENSMUST00000026410.1
Dnajc14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr15_-_102722120 0.300 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr9_+_109096659 0.295 ENSMUST00000130366.1
Plxnb1
plexin B1
chr3_-_131303144 0.295 ENSMUST00000106337.2
Cyp2u1
cytochrome P450, family 2, subfamily u, polypeptide 1
chr2_-_156992021 0.291 ENSMUST00000109558.1
ENSMUST00000069600.6
ENSMUST00000072298.6
Ndrg3


N-myc downstream regulated gene 3


chr10_+_59702645 0.288 ENSMUST00000171409.1
Micu1
mitochondrial calcium uptake 1
chr6_-_122602345 0.287 ENSMUST00000147760.1
ENSMUST00000112585.1
Apobec1

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1

chr6_+_51432678 0.287 ENSMUST00000160133.1
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr13_-_51734695 0.286 ENSMUST00000110039.1
Sema4d
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr7_+_125707893 0.286 ENSMUST00000069660.6
ENSMUST00000142464.1
D430042O09Rik

RIKEN cDNA D430042O09 gene

chr10_+_86302854 0.285 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr6_-_122602404 0.284 ENSMUST00000112586.1
Apobec1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr16_+_91391721 0.283 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr3_+_98013503 0.282 ENSMUST00000079812.6
Notch2
notch 2
chr18_+_36939178 0.281 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chrX_-_7947763 0.281 ENSMUST00000154244.1
Hdac6
histone deacetylase 6
chr3_+_104865062 0.278 ENSMUST00000123876.1
St7l
suppression of tumorigenicity 7-like
chr3_-_68870266 0.278 ENSMUST00000166328.1
Gm17641
predicted gene, 17641
chr19_-_4334001 0.277 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr11_-_54860564 0.276 ENSMUST00000144164.1
Lyrm7
LYR motif containing 7
chr2_+_32535724 0.275 ENSMUST00000133366.1
Fam102a
family with sequence similarity 102, member A
chr19_-_6235804 0.275 ENSMUST00000025695.9
Ppp2r5b
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr1_+_169655493 0.275 ENSMUST00000027997.3
Rgs5
regulator of G-protein signaling 5
chr8_+_123442969 0.274 ENSMUST00000093049.3
ENSMUST00000065534.3
ENSMUST00000001522.3
ENSMUST00000124741.1
ENSMUST00000108832.1
ENSMUST00000132063.1
ENSMUST00000128424.1
Def8






differentially expressed in FDCP 8






chr16_+_14361552 0.271 ENSMUST00000100167.3
ENSMUST00000154748.1
ENSMUST00000134776.1
Abcc1


ATP-binding cassette, sub-family C (CFTR/MRP), member 1


chr17_+_4994904 0.270 ENSMUST00000092723.4
ENSMUST00000115797.2
Arid1b

AT rich interactive domain 1B (SWI-like)

chr12_-_4592927 0.268 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chr10_-_61147659 0.268 ENSMUST00000092498.5
ENSMUST00000137833.1
ENSMUST00000155919.1
Sgpl1


sphingosine phosphate lyase 1


chr2_+_4300462 0.268 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr11_+_97801917 0.266 ENSMUST00000127033.2
Lasp1
LIM and SH3 protein 1
chr12_+_33315393 0.266 ENSMUST00000154742.1
Atxn7l1
ataxin 7-like 1
chr1_+_172499948 0.265 ENSMUST00000111230.1
Tagln2
transgelin 2
chr11_-_110095937 0.265 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr15_-_37459327 0.265 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr7_+_30169861 0.265 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr14_-_51913393 0.264 ENSMUST00000004673.7
ENSMUST00000111632.3
Ndrg2

N-myc downstream regulated gene 2

chr7_+_100706702 0.262 ENSMUST00000049053.7
Fam168a
family with sequence similarity 168, member A
chr13_+_54949388 0.262 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr4_-_46991842 0.261 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr1_-_172297989 0.259 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr2_-_150255591 0.254 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr7_+_19131686 0.253 ENSMUST00000165913.1
Fbxo46
F-box protein 46
chr12_-_102704896 0.250 ENSMUST00000178697.1
ENSMUST00000046518.5
Itpk1

inositol 1,3,4-triphosphate 5/6 kinase

chr9_+_30427329 0.250 ENSMUST00000164099.1
Snx19
sorting nexin 19
chr16_-_34095983 0.250 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr7_-_27181149 0.248 ENSMUST00000071986.6
ENSMUST00000121848.1
Mia

melanoma inhibitory activity

chr6_-_119388671 0.248 ENSMUST00000169744.1
Adipor2
adiponectin receptor 2
chr3_-_107760221 0.248 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr14_-_36919513 0.247 ENSMUST00000182042.1
Ccser2
coiled-coil serine rich 2
chr4_+_102254739 0.243 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr11_-_62458508 0.243 ENSMUST00000141447.1
Ncor1
nuclear receptor co-repressor 1
chr4_-_129662442 0.242 ENSMUST00000003828.4
Kpna6
karyopherin (importin) alpha 6
chr2_-_20943413 0.241 ENSMUST00000140230.1
Arhgap21
Rho GTPase activating protein 21
chr7_+_119690026 0.240 ENSMUST00000047045.8
Acsm4
acyl-CoA synthetase medium-chain family member 4
chr3_+_96181151 0.240 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr11_+_116030304 0.239 ENSMUST00000021116.5
ENSMUST00000106452.1
Unk

unkempt homolog (Drosophila)

chr5_-_44799643 0.238 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr1_-_170867761 0.238 ENSMUST00000027974.6
Atf6
activating transcription factor 6
chr7_-_25005895 0.237 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr5_+_115506668 0.234 ENSMUST00000067268.8
ENSMUST00000086523.3
Pxn

paxillin

chr17_+_8924109 0.233 ENSMUST00000149440.1
Pde10a
phosphodiesterase 10A
chr4_+_102589687 0.230 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr19_-_5273080 0.230 ENSMUST00000025786.7
Pacs1
phosphofurin acidic cluster sorting protein 1
chr6_-_90716489 0.228 ENSMUST00000101153.3
Iqsec1
IQ motif and Sec7 domain 1
chr3_+_28263205 0.228 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr14_-_36919314 0.226 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr2_-_167060417 0.226 ENSMUST00000155281.1
Znfx1
zinc finger, NFX1-type containing 1
chr9_-_108083330 0.226 ENSMUST00000159372.1
ENSMUST00000160249.1
Rnf123

ring finger protein 123

chr19_-_57118897 0.226 ENSMUST00000111526.1
Ablim1
actin-binding LIM protein 1
chr7_-_142666816 0.223 ENSMUST00000105935.1
Igf2
insulin-like growth factor 2
chr19_-_44069690 0.218 ENSMUST00000169092.1
Erlin1
ER lipid raft associated 1
chr7_-_132786914 0.217 ENSMUST00000065371.7
ENSMUST00000106166.1
Fam53b

family with sequence similarity 53, member B

chr3_+_94954075 0.217 ENSMUST00000107260.2
ENSMUST00000142311.1
ENSMUST00000137088.1
ENSMUST00000152869.1
ENSMUST00000107254.1
ENSMUST00000107253.1
Rfx5





regulatory factor X, 5 (influences HLA class II expression)





chr1_-_172219715 0.216 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr14_+_80000292 0.214 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr4_+_41903610 0.213 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr18_+_37355271 0.213 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr3_+_96596628 0.213 ENSMUST00000058943.7
Ankrd34a
ankyrin repeat domain 34A
chr15_-_79834323 0.212 ENSMUST00000177316.2
ENSMUST00000175858.2
Nptxr

neuronal pentraxin receptor

chr2_+_28641227 0.212 ENSMUST00000028155.5
ENSMUST00000113869.1
ENSMUST00000113867.2
Tsc1


tuberous sclerosis 1


chr13_+_60601921 0.212 ENSMUST00000077453.5
Dapk1
death associated protein kinase 1
chr2_+_121358591 0.211 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr17_-_56717681 0.210 ENSMUST00000164907.1
Vmac
vimentin-type intermediate filament associated coiled-coil protein
chr4_-_115133977 0.210 ENSMUST00000051400.7
Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.3 0.9 GO:0046110 xanthine metabolic process(GO:0046110)
0.3 0.9 GO:0016115 terpenoid catabolic process(GO:0016115)
0.3 0.9 GO:0050975 sensory perception of touch(GO:0050975)
0.2 0.7 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.2 1.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 2.0 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 1.1 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.2 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.6 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.2 0.6 GO:1904959 elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.2 0.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.5 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.4 GO:0019046 release from viral latency(GO:0019046)
0.1 0.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.6 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.4 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.4 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 0.6 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.4 GO:0060423 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) negative regulation of mitotic cell cycle, embryonic(GO:0045976) foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.1 0.8 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 0.6 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.3 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.3 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 1.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.2 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.4 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.1 0.3 GO:0042939 glutathione transport(GO:0034635) oligopeptide transmembrane transport(GO:0035672) xenobiotic transport(GO:0042908) tripeptide transport(GO:0042939)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 0.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.3 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 0.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.2 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 0.6 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.1 0.4 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.2 GO:0043379 rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.6 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.2 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 0.2 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.4 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.3 GO:0019532 oxalate transport(GO:0019532)
0.1 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.4 GO:0015879 carnitine transport(GO:0015879)
0.1 1.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.4 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.4 GO:0015074 DNA integration(GO:0015074)
0.1 0.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.4 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 1.1 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.4 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.2 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.2 GO:1904717 positive regulation of synapse structural plasticity(GO:0051835) regulation of AMPA glutamate receptor clustering(GO:1904717)
0.0 0.3 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.1 GO:0015992 proton transport(GO:0015992)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.0 0.2 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:1904048 negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.4 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.1 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.0 0.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.7 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.3 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.0 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.9 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 1.1 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.6 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.2 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.1 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 1.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0060433 bronchus development(GO:0060433) lobar bronchus development(GO:0060482)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.0 0.2 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 1.1 GO:0021766 hippocampus development(GO:0021766)
0.0 0.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.3 GO:0097435 fibril organization(GO:0097435)
0.0 0.0 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.0 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.0 GO:0098501 negative regulation of protein ADP-ribosylation(GO:0010836) polynucleotide dephosphorylation(GO:0098501)
0.0 0.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.0 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.0 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 1.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 0.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.1 GO:0098830 presynaptic endosome(GO:0098830)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:1990597 parallel fiber(GO:1990032) AIP1-IRE1 complex(GO:1990597)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:1990047 spindle matrix(GO:1990047)
0.0 0.2 GO:0016234 inclusion body(GO:0016234)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.2 GO:0042641 actomyosin(GO:0042641)
0.0 0.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 1.6 GO:0050436 microfibril binding(GO:0050436)
0.2 0.9 GO:0030151 molybdenum ion binding(GO:0030151)
0.2 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 0.6 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.2 0.7 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.2 0.5 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 0.9 GO:0019841 retinol binding(GO:0019841)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.8 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.4 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.1 GO:0015250 water channel activity(GO:0015250)
0.1 0.5 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673) sphingolipid transporter activity(GO:0046624)
0.1 0.3 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.4 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 0.3 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 2.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.2 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 0.2 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.2 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 0.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.0 0.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.0 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.0 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.0 0.2 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0005536 glucose binding(GO:0005536) UDP-glucosyltransferase activity(GO:0035251)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.0 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.3 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.0 2.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0015093 iron ion transmembrane transporter activity(GO:0005381) ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.0 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.0 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.6 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.1 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.3 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.0 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.1 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.3 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.3 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.8 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 PID_RHOA_PATHWAY RhoA signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 1.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 0.4 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.3 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.8 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.9 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.6 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.2 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.1 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 1.1 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME_DAG_AND_IP3_SIGNALING Genes involved in DAG and IP3 signaling
0.0 1.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.3 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.1 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants