Motif ID: Sox1

Z-value: 0.339


Transcription factors associated with Sox1:

Gene SymbolEntrez IDGene Name
Sox1 ENSMUSG00000096014.1 Sox1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox1mm10_v2_chr8_+_12395287_123952950.204.2e-01Click!


Activity profile for motif Sox1.

activity profile for motif Sox1


Sorted Z-values histogram for motif Sox1

Sorted Z-values for motif Sox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_119690026 0.841 ENSMUST00000047045.8
Acsm4
acyl-CoA synthetase medium-chain family member 4
chr17_+_34263209 0.472 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr9_-_114390633 0.312 ENSMUST00000084881.4
Crtap
cartilage associated protein
chr5_-_13121766 0.285 ENSMUST00000078246.4
Gm10108
predicted pseudogene 10108
chr17_-_34287770 0.285 ENSMUST00000174751.1
ENSMUST00000040655.6
H2-Aa

histocompatibility 2, class II antigen A, alpha

chr5_+_21737141 0.269 ENSMUST00000030882.5
Pmpcb
peptidase (mitochondrial processing) beta
chr16_-_37654408 0.259 ENSMUST00000023514.3
Ndufb4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr8_+_13159135 0.253 ENSMUST00000033824.6
Lamp1
lysosomal-associated membrane protein 1
chr17_+_47737030 0.238 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr7_+_67655414 0.228 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr12_+_52097737 0.210 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr1_-_195131536 0.207 ENSMUST00000075451.6
Cr1l
complement component (3b/4b) receptor 1-like
chr7_-_46919915 0.196 ENSMUST00000143413.1
ENSMUST00000014546.8
Tsg101

tumor susceptibility gene 101

chr7_+_80343091 0.180 ENSMUST00000032747.5
Hddc3
HD domain containing 3
chrX_+_101429555 0.163 ENSMUST00000033673.6
Nono
non-POU-domain-containing, octamer binding protein
chr6_+_117841174 0.153 ENSMUST00000112859.1
ENSMUST00000137224.1
ENSMUST00000164472.1
ENSMUST00000112861.1
ENSMUST00000035638.8
Zfp637




zinc finger protein 637




chr4_-_131937165 0.151 ENSMUST00000155990.1
Epb4.1
erythrocyte protein band 4.1
chr7_+_101896340 0.144 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr2_-_84650714 0.142 ENSMUST00000111697.2
ENSMUST00000111670.2
ENSMUST00000111696.1
ENSMUST00000111678.1
ENSMUST00000111690.1
ENSMUST00000111695.1
ENSMUST00000111677.1
ENSMUST00000111698.1
ENSMUST00000099941.2
ENSMUST00000111676.1
ENSMUST00000111694.1
ENSMUST00000111675.1
ENSMUST00000111689.1
ENSMUST00000111687.1
ENSMUST00000111692.1
ENSMUST00000111685.1
ENSMUST00000111686.1
ENSMUST00000111688.1
ENSMUST00000111693.1
ENSMUST00000111684.1
Ctnnd1



















catenin (cadherin associated protein), delta 1



















chr2_-_84650760 0.136 ENSMUST00000111691.1
Ctnnd1
catenin (cadherin associated protein), delta 1
chr9_+_44326804 0.121 ENSMUST00000054708.3
Dpagt1
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr10_+_84756055 0.117 ENSMUST00000060397.6
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr1_+_109983737 0.103 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr2_+_34406845 0.090 ENSMUST00000124443.1
ENSMUST00000113124.1
Mapkap1

mitogen-activated protein kinase associated protein 1

chr7_-_127890918 0.085 ENSMUST00000121394.1
Prss53
protease, serine, 53
chrX_+_74297097 0.078 ENSMUST00000019231.5
ENSMUST00000147900.1
ENSMUST00000147275.1
ENSMUST00000114171.3
Atp6ap1



ATPase, H+ transporting, lysosomal accessory protein 1



chr8_+_83165348 0.076 ENSMUST00000034145.4
Tbc1d9
TBC1 domain family, member 9
chr6_+_121183667 0.072 ENSMUST00000118234.1
ENSMUST00000088561.3
ENSMUST00000137432.1
ENSMUST00000120066.1
Pex26



peroxisomal biogenesis factor 26



chr9_-_108305941 0.067 ENSMUST00000044725.7
Tcta
T cell leukemia translocation altered gene
chr2_-_34755229 0.061 ENSMUST00000102800.1
Gapvd1
GTPase activating protein and VPS9 domains 1
chr2_+_84798828 0.048 ENSMUST00000102642.2
ENSMUST00000150325.1
Ube2l6

ubiquitin-conjugating enzyme E2L 6

chr14_-_30923547 0.045 ENSMUST00000170415.1
Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr15_-_76918010 0.029 ENSMUST00000048854.7
Zfp647
zinc finger protein 647
chr17_+_34969912 0.029 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr5_-_140649018 0.027 ENSMUST00000042661.3
Ttyh3
tweety homolog 3 (Drosophila)
chr6_+_114648811 0.026 ENSMUST00000182510.1
Atg7
autophagy related 7
chr15_-_75048837 0.019 ENSMUST00000179762.1
ENSMUST00000065408.9
Ly6c1

lymphocyte antigen 6 complex, locus C1

chr15_-_74997634 0.010 ENSMUST00000023248.6
Ly6a
lymphocyte antigen 6 complex, locus A
chr5_-_129670074 0.009 ENSMUST00000049778.6
Zfp11
zinc finger protein 11
chr3_-_34005490 0.001 ENSMUST00000060997.2
Gm9791
predicted pseudogene 9791

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0002339 B cell selection(GO:0002339)
0.1 0.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.2 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.3 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.8 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.5 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0042605 peptide antigen binding(GO:0042605)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions