Motif ID: Sox1

Z-value: 0.339


Transcription factors associated with Sox1:

Gene SymbolEntrez IDGene Name
Sox1 ENSMUSG00000096014.1 Sox1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox1mm10_v2_chr8_+_12395287_123952950.204.2e-01Click!


Activity profile for motif Sox1.

activity profile for motif Sox1


Sorted Z-values histogram for motif Sox1

Sorted Z-values for motif Sox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox1

PNG image of the network

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Top targets:


Showing 1 to 20 of 40 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_119690026 0.841 ENSMUST00000047045.8
 Acsm4
acyl-CoA synthetase medium-chain family member 4
chr17_+_34263209 0.472 ENSMUST00000040828.5
 H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr9_-_114390633 0.312 ENSMUST00000084881.4
 Crtap
cartilage associated protein
chr5_-_13121766 0.285 ENSMUST00000078246.4
 Gm10108
predicted pseudogene 10108
chr17_-_34287770 0.285 ENSMUST00000174751.1
ENSMUST00000040655.6
 H2-Aa

histocompatibility 2, class II antigen A, alpha

chr5_+_21737141 0.269 ENSMUST00000030882.5
 Pmpcb
peptidase (mitochondrial processing) beta
chr16_-_37654408 0.259 ENSMUST00000023514.3
 Ndufb4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr8_+_13159135 0.253 ENSMUST00000033824.6
 Lamp1
lysosomal-associated membrane protein 1
chr17_+_47737030 0.238 ENSMUST00000086932.3
 Tfeb
transcription factor EB
chr7_+_67655414 0.228 ENSMUST00000107470.1
 Ttc23
tetratricopeptide repeat domain 23
chr12_+_52097737 0.210 ENSMUST00000040090.9
 Nubpl
nucleotide binding protein-like
chr1_-_195131536 0.207 ENSMUST00000075451.6
 Cr1l
complement component (3b/4b) receptor 1-like
chr7_-_46919915 0.196 ENSMUST00000143413.1
ENSMUST00000014546.8
 Tsg101

tumor susceptibility gene 101

chr7_+_80343091 0.180 ENSMUST00000032747.5
 Hddc3
HD domain containing 3
chrX_+_101429555 0.163 ENSMUST00000033673.6
 Nono
non-POU-domain-containing, octamer binding protein
chr6_+_117841174 0.153 ENSMUST00000112859.1
ENSMUST00000137224.1
ENSMUST00000164472.1
ENSMUST00000112861.1
ENSMUST00000035638.8
 Zfp637




zinc finger protein 637




chr4_-_131937165 0.151 ENSMUST00000155990.1
 Epb4.1
erythrocyte protein band 4.1
chr7_+_101896340 0.144 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
 Anapc15


anaphase prompoting complex C subunit 15


chr2_-_84650714 0.142 ENSMUST00000111697.2
ENSMUST00000111670.2
ENSMUST00000111696.1
ENSMUST00000111678.1
ENSMUST00000111690.1
ENSMUST00000111695.1
ENSMUST00000111677.1
ENSMUST00000111698.1
ENSMUST00000099941.2
ENSMUST00000111676.1
ENSMUST00000111694.1
ENSMUST00000111675.1
ENSMUST00000111689.1
ENSMUST00000111687.1
ENSMUST00000111692.1
ENSMUST00000111685.1
ENSMUST00000111686.1
ENSMUST00000111688.1
ENSMUST00000111693.1
ENSMUST00000111684.1
 Ctnnd1



















catenin (cadherin associated protein), delta 1



















chr2_-_84650760 0.136 ENSMUST00000111691.1
 Ctnnd1
catenin (cadherin associated protein), delta 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.5 GO:0002339 B cell selection(GO:0002339)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.3 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.2 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)

Gene overrepresentation in molecular_function category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 0.8 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.5 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.3 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins