Motif ID: Sox11

Z-value: 0.337


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.136.0e-01Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_34965631 0.397 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr9_-_16378231 0.326 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr13_-_41487306 0.293 ENSMUST00000021794.6
 Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr11_+_69364010 0.275 ENSMUST00000166700.1
 Gm17305
predicted gene, 17305
chr9_+_89909775 0.225 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr14_-_52213379 0.206 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr5_+_144100387 0.203 ENSMUST00000041804.7
 Lmtk2
lemur tyrosine kinase 2
chr2_+_3114220 0.179 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr17_+_43016536 0.172 ENSMUST00000024708.4
 Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr10_+_121365078 0.170 ENSMUST00000040344.6
 Gns
glucosamine (N-acetyl)-6-sulfatase
chr11_-_50292302 0.161 ENSMUST00000059458.4
 Maml1
mastermind like 1 (Drosophila)
chr1_+_82233112 0.160 ENSMUST00000023262.5
 Gm9747
predicted gene 9747
chr9_-_51102062 0.156 ENSMUST00000170947.1
 4833427G06Rik
RIKEN cDNA 4833427G06 gene
chr5_+_89027959 0.151 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chrX_+_56786527 0.145 ENSMUST00000144600.1
 Fhl1
four and a half LIM domains 1
chr5_-_87490869 0.139 ENSMUST00000147854.1
 Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr13_-_113618549 0.132 ENSMUST00000109241.3
 Snx18
sorting nexin 18
chr5_+_145084100 0.121 ENSMUST00000124379.1
 Arpc1a
actin related protein 2/3 complex, subunit 1A
chr9_+_32116040 0.118 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr19_-_46969474 0.116 ENSMUST00000086961.7
 Nt5c2
5'-nucleotidase, cytosolic II
chr16_+_8830093 0.115 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr4_-_44072578 0.115 ENSMUST00000173383.1
 Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr7_-_105737376 0.112 ENSMUST00000098148.4
 Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr9_+_65890237 0.108 ENSMUST00000045802.6
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr2_-_109278274 0.102 ENSMUST00000081631.3
 Mettl15
methyltransferase like 15
chr6_-_23248264 0.097 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr1_-_45503282 0.097 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr5_+_121795034 0.096 ENSMUST00000162327.1
 Atxn2
ataxin 2
chr10_+_24869982 0.095 ENSMUST00000092646.6
 Med23
mediator complex subunit 23
chr3_+_67430096 0.092 ENSMUST00000077271.6
ENSMUST00000161009.1
 Gfm1

G elongation factor, mitochondrial 1

chr15_+_76797628 0.091 ENSMUST00000165535.2
 Gm17271
predicted gene, 17271
chr11_+_98937669 0.089 ENSMUST00000107475.2
ENSMUST00000068133.3
 Rara

retinoic acid receptor, alpha

chr12_+_8921598 0.087 ENSMUST00000020909.3
 Laptm4a
lysosomal-associated protein transmembrane 4A
chr13_-_84064772 0.085 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr16_-_50330987 0.085 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr13_+_40859768 0.083 ENSMUST00000110191.2
 Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr14_-_47418407 0.076 ENSMUST00000043296.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr14_-_121698417 0.072 ENSMUST00000040700.7
 Dock9
dedicator of cytokinesis 9
chr2_-_119662756 0.068 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
 Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr11_-_69369377 0.068 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr15_-_81104999 0.066 ENSMUST00000109579.2
 Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr2_-_156111954 0.065 ENSMUST00000142960.2
ENSMUST00000136296.2
ENSMUST00000059647.5
ENSMUST00000109604.2
ENSMUST00000138068.1
ENSMUST00000128499.1
 Cpne1

Rbm12



copine I

RNA binding motif protein 12



chr4_-_149774238 0.058 ENSMUST00000105686.2
 Slc25a33
solute carrier family 25, member 33
chr7_-_55962466 0.057 ENSMUST00000032635.7
ENSMUST00000152649.1
 Nipa2

non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

chr16_-_44558864 0.055 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr2_+_157279026 0.055 ENSMUST00000116380.2
 Rpn2
ribophorin II
chr1_+_44119952 0.053 ENSMUST00000114709.2
 Bivm
basic, immunoglobulin-like variable motif containing
chr1_-_162866502 0.048 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr17_-_29007925 0.048 ENSMUST00000009138.5
ENSMUST00000119274.1
 Stk38

serine/threonine kinase 38

chr2_+_157279065 0.047 ENSMUST00000029171.5
 Rpn2
ribophorin II
chr16_-_44558879 0.046 ENSMUST00000114634.1
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr11_+_4873951 0.045 ENSMUST00000038570.2
 Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr6_-_42693087 0.045 ENSMUST00000121083.1
 Fam115a
family with sequence similarity 115, member A
chr19_+_8837676 0.041 ENSMUST00000159634.1
 Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr2_-_127247768 0.037 ENSMUST00000003759.4
 Ciao1
cytosolic iron-sulfur protein assembly 1
chr6_-_60829826 0.037 ENSMUST00000163779.1
 Snca
synuclein, alpha
chr7_+_70388305 0.037 ENSMUST00000080024.5
 B130024G19Rik
RIKEN cDNA B130024G19 gene
chr2_-_36136602 0.036 ENSMUST00000122456.1
 Rbm18
RNA binding motif protein 18
chr7_+_83631959 0.035 ENSMUST00000075418.7
ENSMUST00000117410.1
 Stard5

StAR-related lipid transfer (START) domain containing 5

chr13_-_99516537 0.035 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr5_+_8046077 0.035 ENSMUST00000088786.4
 Sri
sorcin
chr2_-_127247620 0.033 ENSMUST00000174030.1
ENSMUST00000174863.1
 Ciao1

cytosolic iron-sulfur protein assembly 1

chrX_+_166344692 0.031 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr5_+_145083830 0.030 ENSMUST00000031625.8
 Arpc1a
actin related protein 2/3 complex, subunit 1A
chr5_-_148552783 0.029 ENSMUST00000079324.7
ENSMUST00000164904.1
 Ubl3

ubiquitin-like 3

chr9_+_107888129 0.029 ENSMUST00000035202.2
 Mon1a
MON1 homolog A (yeast)
chr6_-_42693030 0.028 ENSMUST00000045140.4
 Fam115a
family with sequence similarity 115, member A
chr5_+_64812336 0.026 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)
chr4_+_59003121 0.026 ENSMUST00000095070.3
ENSMUST00000174664.1
 Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr13_+_24327415 0.025 ENSMUST00000167746.1
 Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr4_-_129378116 0.022 ENSMUST00000030610.2
 Zbtb8a
zinc finger and BTB domain containing 8a
chr10_+_115569986 0.021 ENSMUST00000173620.1
 A930009A15Rik
RIKEN cDNA A930009A15 gene
chr3_+_60877002 0.019 ENSMUST00000099086.2
 Gm8325
predicted pseudogene 8325
chr9_+_101074727 0.014 ENSMUST00000085177.3
 Msl2
male-specific lethal 2 homolog (Drosophila)
chr11_+_24080664 0.009 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chrX_+_85574018 0.008 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
 Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr4_-_43030440 0.005 ENSMUST00000135660.1
 Stoml2
stomatin (Epb7.2)-like 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.0 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0032052 bile acid binding(GO:0032052)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism