Motif ID: Sox13

Z-value: 0.382


Transcription factors associated with Sox13:

Gene SymbolEntrez IDGene Name
Sox13 ENSMUSG00000070643.5 Sox13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox13mm10_v2_chr1_-_133424377_133424404-0.262.9e-01Click!


Activity profile for motif Sox13.

activity profile for motif Sox13


Sorted Z-values histogram for motif Sox13

Sorted Z-values for motif Sox13



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_96210107 1.676 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr8_-_84773381 1.066 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr1_+_19103022 0.819 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr9_-_75597643 0.811 ENSMUST00000164100.1
 Tmod2
tropomodulin 2
chr8_-_11008458 0.726 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr2_-_36104060 0.722 ENSMUST00000112961.3
ENSMUST00000112966.3
 Lhx6

LIM homeobox protein 6

chr1_-_93101825 0.546 ENSMUST00000112958.2
 Kif1a
kinesin family member 1A
chr18_+_69593361 0.546 ENSMUST00000114978.2
ENSMUST00000114977.1
 Tcf4

transcription factor 4

chr18_+_64887690 0.527 ENSMUST00000163516.1
 Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr13_-_66851513 0.419 ENSMUST00000169322.1
 Gm17404
predicted gene, 17404
chr14_-_121698417 0.405 ENSMUST00000040700.7
 Dock9
dedicator of cytokinesis 9
chr1_+_17145357 0.357 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr7_-_132813095 0.341 ENSMUST00000106165.1
 Fam53b
family with sequence similarity 53, member B
chr13_-_66852017 0.332 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr17_-_68004075 0.332 ENSMUST00000024840.5
 Arhgap28
Rho GTPase activating protein 28
chr5_-_8367982 0.304 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
 Adam22






a disintegrin and metallopeptidase domain 22






chr7_+_24271568 0.252 ENSMUST00000032696.6
 Zfp93
zinc finger protein 93
chr14_-_47568427 0.242 ENSMUST00000042988.6
 Atg14
autophagy related 14
chr18_+_37355271 0.187 ENSMUST00000051163.1
 Pcdhb8
protocadherin beta 8
chr19_-_19001099 0.180 ENSMUST00000040153.8
ENSMUST00000112828.1
 Rorb

RAR-related orphan receptor beta

chr12_+_36314160 0.135 ENSMUST00000041407.5
 Sostdc1
sclerostin domain containing 1
chr15_-_50890396 0.126 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr16_-_28929658 0.125 ENSMUST00000100023.1
 Mb21d2
Mab-21 domain containing 2
chr2_+_176236860 0.078 ENSMUST00000166464.1
 2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr4_+_103143052 0.074 ENSMUST00000106855.1
 Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr3_-_96058446 0.061 ENSMUST00000015891.5
 Vps45
vacuolar protein sorting 45 (yeast)
chr1_+_39900883 0.048 ENSMUST00000163854.2
ENSMUST00000168431.1
 Map4k4

mitogen-activated protein kinase kinase kinase kinase 4

chr2_+_25180737 0.047 ENSMUST00000104999.2
 Nrarp
Notch-regulated ankyrin repeat protein
chr4_+_48585276 0.047 ENSMUST00000123476.1
 Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr10_-_116473418 0.018 ENSMUST00000087965.4
ENSMUST00000164271.1
 Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.7 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.5 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.7 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.1 1.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.8 GO:0030901 midbrain development(GO:0030901)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.5 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_EPO_PATHWAY EPO signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME_MYOGENESIS Genes involved in Myogenesis