Motif ID: Sox14
Z-value: 0.920
Transcription factors associated with Sox14:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Sox14 | ENSMUSG00000053747.8 | Sox14 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sox14 | mm10_v2_chr9_-_99876147_99876193 | -0.11 | 6.6e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 112 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.9 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 1.1 | 3.4 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
| 0.0 | 2.9 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.1 | 2.4 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.0 | 2.4 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.0 | 2.2 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 1.9 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.0 | 1.9 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 1.9 | GO:0032410 | negative regulation of transporter activity(GO:0032410) |
| 0.4 | 1.8 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.1 | 1.8 | GO:0032808 | lacrimal gland development(GO:0032808) |
| 0.4 | 1.7 | GO:0032289 | central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912) |
| 0.1 | 1.7 | GO:0022401 | desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) |
| 0.0 | 1.6 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.1 | 1.4 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 1.3 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.1 | 1.2 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.1 | 1.2 | GO:0048875 | chemical homeostasis within a tissue(GO:0048875) |
| 0.0 | 1.2 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.4 | 1.1 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 42 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.1 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 2.6 | GO:0042641 | actomyosin(GO:0042641) |
| 0.1 | 1.4 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 1.2 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 1.2 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 1.1 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 1.1 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.1 | 1.0 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.0 | 1.0 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 1.0 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.2 | 0.9 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.1 | 0.9 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.0 | 0.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 0.8 | GO:0098845 | postsynaptic endosome(GO:0098845) |
| 0.0 | 0.8 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 0.8 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 0.8 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 0.7 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 0.7 | GO:0005938 | cell cortex(GO:0005938) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 73 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.7 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 4.5 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 1.1 | 3.4 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
| 0.0 | 2.8 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.1 | 2.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 2.2 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 2.1 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.2 | 1.9 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.0 | 1.9 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.4 | 1.8 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.1 | 1.7 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.0 | 1.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 1.4 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.1 | 1.2 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.0 | 1.2 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.2 | 1.1 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.0 | 1.1 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.3 | 1.0 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.2 | 1.0 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.1 | 1.0 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
Gene overrepresentation in C2:CP category:
Showing 1 to 15 of 15 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.6 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 1.6 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.3 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.2 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
| 0.0 | 1.0 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.9 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.7 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.6 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.0 | 0.5 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.0 | 0.5 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.0 | 0.4 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.4 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.4 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.3 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.3 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 30 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 1.9 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 1.8 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 1.4 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 1.3 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 1.2 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.0 | 1.0 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 1.0 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 1.0 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 0.9 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 0.9 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.9 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 0.8 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 0.8 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.8 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.0 | 0.8 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 0.7 | REACTOME_IRAK1_RECRUITS_IKK_COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.7 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.7 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.7 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
