Motif ID: Sox15

Z-value: 0.449


Transcription factors associated with Sox15:

Gene SymbolEntrez IDGene Name
Sox15 ENSMUSG00000041287.5 Sox15



Activity profile for motif Sox15.

activity profile for motif Sox15


Sorted Z-values histogram for motif Sox15

Sorted Z-values for motif Sox15



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox15

PNG image of the network

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Top targets:


Showing 1 to 20 of 127 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 1.542 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr10_+_53596936 1.166 ENSMUST00000020004.6
 Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr7_-_49636847 1.022 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr14_-_48662740 0.893 ENSMUST00000122009.1
 Otx2
orthodenticle homolog 2 (Drosophila)
chr19_+_55741810 0.792 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr7_+_82867327 0.680 ENSMUST00000082237.5
 Mex3b
mex3 homolog B (C. elegans)
chr17_-_70851189 0.670 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr18_+_11633276 0.656 ENSMUST00000115861.2
 Rbbp8
retinoblastoma binding protein 8
chr10_-_37138863 0.623 ENSMUST00000092584.5
 Marcks
myristoylated alanine rich protein kinase C substrate
chrX_+_109095359 0.606 ENSMUST00000033598.8
 Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr11_+_88068242 0.592 ENSMUST00000018521.4
 Vezf1
vascular endothelial zinc finger 1
chr3_-_8964037 0.556 ENSMUST00000091354.5
ENSMUST00000094381.4
 Tpd52

tumor protein D52

chr1_-_138842429 0.550 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr12_-_40445754 0.530 ENSMUST00000069692.8
ENSMUST00000069637.7
 Zfp277

zinc finger protein 277

chrX_+_112604274 0.504 ENSMUST00000071814.6
 Zfp711
zinc finger protein 711
chr13_+_21722057 0.500 ENSMUST00000110476.3
 Hist1h2bm
histone cluster 1, H2bm
chr9_-_103480328 0.475 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chr3_+_37639985 0.442 ENSMUST00000108107.1
 Spry1
sprouty homolog 1 (Drosophila)
chr4_-_34882919 0.434 ENSMUST00000098163.2
ENSMUST00000047950.5
 Zfp292

zinc finger protein 292

chr19_-_46039621 0.432 ENSMUST00000056931.7
 Ldb1
LIM domain binding 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 1.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 0.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.7 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 0.7 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.6 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.5 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.5 GO:2000772 regulation of cellular senescence(GO:2000772)
0.1 0.4 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.4 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.4 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.8 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.2 0.6 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.2 0.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.7 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.1 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.6 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism