Motif ID: Sox18_Sox12

Z-value: 0.654

Transcription factors associated with Sox18_Sox12:

Gene SymbolEntrez IDGene Name
Sox12 ENSMUSG00000051817.8 Sox12
Sox18 ENSMUSG00000046470.5 Sox18

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox12mm10_v2_chr2_-_152398046_1523980760.484.6e-02Click!
Sox18mm10_v2_chr2_-_181671622_181671645-0.107.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Sox18_Sox12

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_11970540 1.623 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr6_-_113934679 1.386 ENSMUST00000101044.2
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr9_-_60511003 1.367 ENSMUST00000098660.3
Thsd4
thrombospondin, type I, domain containing 4
chr18_-_74961252 1.293 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr18_-_88927447 1.262 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr14_+_62837679 1.176 ENSMUST00000014691.8
Wdfy2
WD repeat and FYVE domain containing 2
chr16_-_23520579 1.130 ENSMUST00000089883.5
Masp1
mannan-binding lectin serine peptidase 1
chr7_+_24271568 0.995 ENSMUST00000032696.6
Zfp93
zinc finger protein 93
chr2_+_25180737 0.947 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chrX_+_56779699 0.945 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
Fhl1


four and a half LIM domains 1


chr19_-_34527396 0.937 ENSMUST00000049572.8
ENSMUST00000178114.1
Lipa

lysosomal acid lipase A

chr14_+_116925379 0.895 ENSMUST00000088483.3
Gpc6
glypican 6
chr4_-_58499398 0.891 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr16_-_91618986 0.871 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
Dnajc28



DnaJ (Hsp40) homolog, subfamily C, member 28



chr7_+_75643223 0.837 ENSMUST00000137959.1
Akap13
A kinase (PRKA) anchor protein 13
chr11_-_62392605 0.835 ENSMUST00000151498.2
ENSMUST00000159069.1
Ncor1

nuclear receptor co-repressor 1

chr5_+_92809372 0.784 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr2_+_119034783 0.611 ENSMUST00000028796.1
Rpusd2
RNA pseudouridylate synthase domain containing 2
chr14_-_100149764 0.584 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr1_-_133921393 0.583 ENSMUST00000048432.5
Prelp
proline arginine-rich end leucine-rich repeat
chr13_-_25020289 0.575 ENSMUST00000021772.2
Mrs2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr15_+_25742314 0.570 ENSMUST00000135981.1
Myo10
myosin X
chr5_+_48242549 0.547 ENSMUST00000172493.1
Slit2
slit homolog 2 (Drosophila)
chrY_-_1286563 0.495 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr16_-_22161450 0.489 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr4_+_134396320 0.486 ENSMUST00000105869.2
Pafah2
platelet-activating factor acetylhydrolase 2
chr16_-_50330987 0.476 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr5_+_96173940 0.473 ENSMUST00000048361.8
Gm2840
predicted gene 2840
chr3_-_108402589 0.472 ENSMUST00000147565.1
Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr16_+_38562821 0.470 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr14_-_118052235 0.467 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr7_+_100493795 0.453 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr4_-_131937165 0.451 ENSMUST00000155990.1
Epb4.1
erythrocyte protein band 4.1
chr2_-_59948155 0.444 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr11_-_106998483 0.437 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr15_+_25773985 0.431 ENSMUST00000125667.1
Myo10
myosin X
chrX_-_70477170 0.420 ENSMUST00000101506.3
ENSMUST00000114630.2
BC023829

cDNA sequence BC023829

chr1_-_72212249 0.402 ENSMUST00000048860.7
Mreg
melanoregulin
chr8_-_22694061 0.395 ENSMUST00000131767.1
Ikbkb
inhibitor of kappaB kinase beta
chr1_-_169747634 0.380 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chr4_-_116405986 0.375 ENSMUST00000123072.1
ENSMUST00000144281.1
Mast2

microtubule associated serine/threonine kinase 2

chr7_+_75455534 0.354 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr7_+_100494044 0.346 ENSMUST00000153287.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chrM_+_9870 0.346 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr5_+_144100387 0.344 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr8_-_67910911 0.338 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr3_+_67430096 0.336 ENSMUST00000077271.6
ENSMUST00000161009.1
Gfm1

G elongation factor, mitochondrial 1

chr1_-_24612700 0.336 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr1_-_93101825 0.332 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr7_+_19228334 0.328 ENSMUST00000063976.8
Opa3
optic atrophy 3
chr2_+_154436437 0.303 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr18_+_7869707 0.301 ENSMUST00000166062.1
ENSMUST00000169010.1
Wac

WW domain containing adaptor with coiled-coil

chrX_+_9885622 0.298 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr11_-_109472611 0.298 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr1_+_66386968 0.294 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr2_+_101678403 0.291 ENSMUST00000004949.7
Traf6
TNF receptor-associated factor 6
chr16_-_63864114 0.284 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr4_-_115133977 0.284 ENSMUST00000051400.7
Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1
chr17_-_25844417 0.276 ENSMUST00000176591.1
Rhot2
ras homolog gene family, member T2
chr18_+_69593361 0.273 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chrM_+_11734 0.272 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr15_+_100038635 0.267 ENSMUST00000100203.3
Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr16_+_16896469 0.263 ENSMUST00000027373.9
Ppm1f
protein phosphatase 1F (PP2C domain containing)
chr11_-_69369377 0.262 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr2_-_27463994 0.262 ENSMUST00000164296.1
Brd3
bromodomain containing 3
chr1_+_136467958 0.252 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr2_+_55411790 0.248 ENSMUST00000155997.1
ENSMUST00000128307.1
Gm14033

predicted gene 14033

chr3_-_142169196 0.245 ENSMUST00000098568.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr16_+_38562806 0.244 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chrX_+_101274023 0.244 ENSMUST00000117706.1
Med12
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chr8_-_84773381 0.240 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr4_-_136886187 0.234 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr10_-_88605017 0.225 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr15_+_6422240 0.225 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr2_-_26122769 0.221 ENSMUST00000140993.1
ENSMUST00000028300.5
Nacc2

nucleus accumbens associated 2, BEN and BTB (POZ) domain containing

chr8_+_84946987 0.221 ENSMUST00000067472.7
ENSMUST00000109740.2
Rtbdn

retbindin

chr7_+_127800604 0.220 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr4_-_136835843 0.219 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Ephb2


Eph receptor B2


chr3_-_19264959 0.218 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr1_+_34005872 0.217 ENSMUST00000182296.1
Dst
dystonin
chr1_-_155527083 0.216 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr16_+_21891969 0.214 ENSMUST00000042065.6
Map3k13
mitogen-activated protein kinase kinase kinase 13
chr7_+_80186835 0.213 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

chr6_-_25809210 0.212 ENSMUST00000115330.1
ENSMUST00000115329.1
Pot1a

protection of telomeres 1A

chrX_+_142227923 0.212 ENSMUST00000042329.5
Nxt2
nuclear transport factor 2-like export factor 2
chr3_+_4211716 0.212 ENSMUST00000170943.1
Gm8775
predicted gene 8775
chr10_+_72309225 0.209 ENSMUST00000061324.4
Gm9923
predicted pseudogene 9923
chr14_-_47418407 0.208 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr15_-_102722120 0.208 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr18_-_66022580 0.206 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr6_-_42645254 0.203 ENSMUST00000031879.3
Fam115c
family with sequence similarity 115, member C
chr1_+_165788681 0.192 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr4_+_130663321 0.191 ENSMUST00000030315.6
ENSMUST00000105992.2
ENSMUST00000105991.2
ENSMUST00000143277.1
ENSMUST00000097864.2
ENSMUST00000097862.2
Pum1





pumilio 1 (Drosophila)





chr11_-_89538556 0.191 ENSMUST00000169201.1
Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr4_-_41870612 0.185 ENSMUST00000179680.1
Gm21966
predicted gene, 21966
chr8_+_123062942 0.184 ENSMUST00000142541.1
ENSMUST00000125975.1
Spg7

spastic paraplegia 7 homolog (human)

chr10_+_24869998 0.182 ENSMUST00000020159.8
Med23
mediator complex subunit 23
chr6_-_108185552 0.180 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr19_-_53589067 0.180 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chrX_+_140367494 0.179 ENSMUST00000141660.1
Frmpd3
FERM and PDZ domain containing 3
chr4_+_62525369 0.176 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr5_-_5559501 0.176 ENSMUST00000119521.1
Gtpbp10
GTP-binding protein 10 (putative)
chr8_+_116921735 0.175 ENSMUST00000034205.4
Cenpn
centromere protein N
chr15_-_102722150 0.173 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr8_-_110997764 0.173 ENSMUST00000040416.7
Ddx19a
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
chr7_+_129591859 0.172 ENSMUST00000084519.5
Wdr11
WD repeat domain 11
chr2_+_3713478 0.171 ENSMUST00000115053.2
Fam107b
family with sequence similarity 107, member B
chr13_+_40859768 0.171 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr1_+_12718496 0.171 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr11_-_26591729 0.170 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr4_+_137993016 0.170 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
Eif4g3



eukaryotic translation initiation factor 4 gamma, 3



chr9_-_75597643 0.169 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr8_-_11008458 0.167 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr2_-_129297205 0.166 ENSMUST00000052708.6
Ckap2l
cytoskeleton associated protein 2-like
chr17_-_31519914 0.164 ENSMUST00000167419.1
ENSMUST00000171291.1
Wdr4

WD repeat domain 4

chrX_+_142228177 0.164 ENSMUST00000112914.1
Nxt2
nuclear transport factor 2-like export factor 2
chr2_+_4559742 0.162 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr11_-_90687572 0.162 ENSMUST00000107869.2
ENSMUST00000154599.1
ENSMUST00000107868.1
ENSMUST00000020849.2
Tom1l1



target of myb1-like 1 (chicken)



chr18_-_39487096 0.161 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr4_-_14621494 0.156 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr3_+_96104498 0.154 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
Otud7b



OTU domain containing 7B



chr12_-_10900296 0.149 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chrX_+_106920618 0.147 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr17_+_29660595 0.146 ENSMUST00000024816.6
Cmtr1
cap methyltransferase 1
chr9_+_122923050 0.145 ENSMUST00000051667.7
ENSMUST00000148851.1
Zfp105

zinc finger protein 105

chr18_+_65580230 0.145 ENSMUST00000049016.5
ENSMUST00000183236.1
Zfp532

zinc finger protein 532

chr1_-_162548484 0.145 ENSMUST00000028017.9
Mettl13
methyltransferase like 13
chr12_+_33314277 0.144 ENSMUST00000133549.1
Atxn7l1
ataxin 7-like 1
chr9_-_48480540 0.144 ENSMUST00000034524.3
Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr1_+_109993982 0.143 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr2_+_176236860 0.143 ENSMUST00000166464.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr10_+_24869982 0.143 ENSMUST00000092646.6
Med23
mediator complex subunit 23
chr6_-_3494587 0.140 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr9_-_110375430 0.137 ENSMUST00000168137.1
5830462I19Rik
RIKEN cDNA 5830462I19 gene
chr16_-_3908596 0.136 ENSMUST00000123235.2
1700037C18Rik
RIKEN cDNA 1700037C18 gene
chr17_-_25844514 0.136 ENSMUST00000176709.1
Rhot2
ras homolog gene family, member T2
chr1_-_119837613 0.136 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr13_+_24327415 0.135 ENSMUST00000167746.1
Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr9_+_52047150 0.129 ENSMUST00000163153.1
Rdx
radixin
chr15_-_77153772 0.125 ENSMUST00000166610.1
ENSMUST00000111581.2
Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr5_+_8046077 0.122 ENSMUST00000088786.4
Sri
sorcin
chr2_-_160859601 0.121 ENSMUST00000103112.1
Zhx3
zinc fingers and homeoboxes 3
chr1_+_44119952 0.121 ENSMUST00000114709.2
Bivm
basic, immunoglobulin-like variable motif containing
chr12_+_117843489 0.121 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr5_-_88526496 0.121 ENSMUST00000164073.1
Igj
immunoglobulin joining chain
chr2_+_102706356 0.118 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr19_+_4711153 0.117 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr2_-_84775420 0.113 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr11_-_5837760 0.112 ENSMUST00000109837.1
Polm
polymerase (DNA directed), mu
chr5_+_34999111 0.111 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr3_+_76075583 0.110 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr3_+_63295815 0.110 ENSMUST00000029400.1
Mme
membrane metallo endopeptidase
chr2_+_4882204 0.102 ENSMUST00000115019.1
Sephs1
selenophosphate synthetase 1
chr5_+_30647921 0.102 ENSMUST00000062962.5
Slc35f6
solute carrier family 35, member F6
chr5_+_34999070 0.100 ENSMUST00000114280.1
Rgs12
regulator of G-protein signaling 12
chr2_-_69712461 0.100 ENSMUST00000102706.3
ENSMUST00000073152.6
Fastkd1

FAST kinase domains 1

chr2_-_119662756 0.099 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr12_-_102423741 0.098 ENSMUST00000110020.1
Lgmn
legumain
chr19_-_24961545 0.098 ENSMUST00000025815.8
Cbwd1
COBW domain containing 1
chr9_-_72111651 0.095 ENSMUST00000185117.1
Tcf12
transcription factor 12
chr19_+_46623387 0.094 ENSMUST00000111855.4
Wbp1l
WW domain binding protein 1 like
chr10_+_97482350 0.093 ENSMUST00000163448.2
Dcn
decorin
chr9_-_108079255 0.088 ENSMUST00000162516.1
Rnf123
ring finger protein 123
chr9_-_36797303 0.088 ENSMUST00000115086.5
Ei24
etoposide induced 2.4 mRNA
chr13_-_66851513 0.087 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr8_-_45410539 0.086 ENSMUST00000034056.4
ENSMUST00000167106.1
Tlr3

toll-like receptor 3

chr2_+_112284561 0.086 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr4_-_15945359 0.086 ENSMUST00000029877.8
Decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr11_-_113751813 0.085 ENSMUST00000053536.4
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr17_-_34118476 0.083 ENSMUST00000095347.5
Brd2
bromodomain containing 2
chr11_+_4873951 0.082 ENSMUST00000038570.2
Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr7_-_105787567 0.081 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr1_-_97761538 0.081 ENSMUST00000171129.1
Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr7_+_128265675 0.080 ENSMUST00000118169.1
ENSMUST00000142841.1
Slc5a2

solute carrier family 5 (sodium/glucose cotransporter), member 2

chr16_-_59632520 0.080 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr4_-_150003130 0.079 ENSMUST00000084117.6
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr1_+_55406163 0.078 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr1_-_119837338 0.076 ENSMUST00000163435.1
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr4_+_42714926 0.075 ENSMUST00000178454.1
Gm21955
predicted gene, 21955
chr18_+_37742088 0.075 ENSMUST00000003599.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr12_-_79007276 0.075 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr11_+_4986824 0.071 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr1_-_155146755 0.070 ENSMUST00000027744.8
Mr1
major histocompatibility complex, class I-related
chr9_-_108079279 0.070 ENSMUST00000162355.1
ENSMUST00000047746.6
ENSMUST00000174504.1
ENSMUST00000178267.1
ENSMUST00000160649.1
Rnf123




ring finger protein 123




chr11_+_6560183 0.070 ENSMUST00000109722.2
Ccm2
cerebral cavernous malformation 2
chr5_+_34999046 0.069 ENSMUST00000114281.1
Rgs12
regulator of G-protein signaling 12
chr11_+_59306920 0.066 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr5_-_24577467 0.064 ENSMUST00000030795.8
Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr1_+_131867224 0.064 ENSMUST00000112386.1
ENSMUST00000027693.7
Rab7l1

RAB7, member RAS oncogene family-like 1

chr18_-_40219324 0.064 ENSMUST00000025364.4
Yipf5
Yip1 domain family, member 5
chr2_+_102659213 0.062 ENSMUST00000111213.1
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr9_+_102834864 0.061 ENSMUST00000175883.1
Ryk
receptor-like tyrosine kinase
chr4_-_110287479 0.061 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr9_+_99575776 0.059 ENSMUST00000066650.5
ENSMUST00000148987.1
Dbr1

debranching enzyme homolog 1 (S. cerevisiae)

chr4_+_43384332 0.058 ENSMUST00000136360.1
Rusc2
RUN and SH3 domain containing 2
chr1_+_165788746 0.058 ENSMUST00000161559.2
Cd247
CD247 antigen
chr4_-_129239165 0.056 ENSMUST00000097873.3
C77080
expressed sequence C77080
chr4_-_14621669 0.056 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr11_+_64979025 0.056 ENSMUST00000071891.5
ENSMUST00000108697.1
ENSMUST00000101049.2
Elac2


elaC homolog 2 (E. coli)


chr10_-_6980376 0.054 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.2 1.4 GO:0048840 otolith development(GO:0048840)
0.2 0.9 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.8 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.2 1.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2 0.5 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.2 1.6 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.5 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.3 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 0.3 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.8 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.9 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.3 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 0.9 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.6 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 0.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.4 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.2 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:0045349 regulation of dendritic cell cytokine production(GO:0002730) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-beta biosynthetic process(GO:0045359) necroptotic signaling pathway(GO:0097527)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.3 GO:0033572 transferrin transport(GO:0033572)
0.0 0.1 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.4 GO:0042640 anagen(GO:0042640)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.9 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.9 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.1 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 1.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.4 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 1.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.0 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.0 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.0 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0070207 protein homotrimerization(GO:0070207)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.9 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.1 1.4 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0005923 bicellular tight junction(GO:0005923) apical junction complex(GO:0043296) occluding junction(GO:0070160)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.0 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 2.8 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 0.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.0 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.2 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.1 0.5 GO:0048495 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0070330 aromatase activity(GO:0070330)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 0.5 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.1 GO:0016298 lipase activity(GO:0016298)
0.0 0.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.0 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID_IGF1_PATHWAY IGF1 pathway
0.0 1.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 1.0 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.2 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 1.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.2 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.3 PID_EPHA_FWDPATHWAY EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.4 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 0.2 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.3 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.6 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.7 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.8 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.0 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex