Motif ID: Sox30

Z-value: 0.363


Transcription factors associated with Sox30:

Gene SymbolEntrez IDGene Name
Sox30 ENSMUSG00000040489.5 Sox30



Activity profile for motif Sox30.

activity profile for motif Sox30


Sorted Z-values histogram for motif Sox30

Sorted Z-values for motif Sox30



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox30

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 1.999 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chrX_-_134161928 1.314 ENSMUST00000033611.4
 Xkrx
X Kell blood group precursor related X linked
chr6_-_3494587 0.816 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr9_+_7764041 0.757 ENSMUST00000052865.9
 Tmem123
transmembrane protein 123
chr10_+_17796256 0.700 ENSMUST00000037964.6
 Txlnb
taxilin beta
chr5_+_92809372 0.695 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr9_-_103480328 0.689 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chr14_-_19823807 0.656 ENSMUST00000022341.5
 2700060E02Rik
RIKEN cDNA 2700060E02 gene
chr3_+_34649987 0.624 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr13_-_102958084 0.563 ENSMUST00000099202.3
ENSMUST00000172264.1
 Mast4

microtubule associated serine/threonine kinase family member 4

chr14_+_116925379 0.547 ENSMUST00000088483.3
 Gpc6
glypican 6
chr18_-_62756275 0.540 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr2_-_101883010 0.453 ENSMUST00000154525.1
 Prr5l
proline rich 5 like
chrX_+_56786527 0.449 ENSMUST00000144600.1
 Fhl1
four and a half LIM domains 1
chr18_-_88927447 0.444 ENSMUST00000147313.1
 Socs6
suppressor of cytokine signaling 6
chr12_-_99883429 0.384 ENSMUST00000046485.3
 Efcab11
EF-hand calcium binding domain 11
chr13_-_56135629 0.356 ENSMUST00000016081.6
ENSMUST00000045788.7
 H2afy

H2A histone family, member Y

chr2_-_58052832 0.299 ENSMUST00000090940.5
 Ermn
ermin, ERM-like protein
chr19_+_44293676 0.281 ENSMUST00000026221.5
 Scd2
stearoyl-Coenzyme A desaturase 2
chr3_-_8964037 0.245 ENSMUST00000091354.5
ENSMUST00000094381.4
 Tpd52

tumor protein D52

chr2_+_3114220 0.222 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr7_+_90426312 0.214 ENSMUST00000061391.7
 Ccdc89
coiled-coil domain containing 89
chr19_-_24477356 0.213 ENSMUST00000099556.1
 Fam122a
family with sequence similarity 122, member A
chr17_-_79355082 0.205 ENSMUST00000068958.7
 Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr9_-_60511003 0.186 ENSMUST00000098660.3
 Thsd4
thrombospondin, type I, domain containing 4
chr10_+_14523062 0.185 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr5_-_17835857 0.175 ENSMUST00000082367.6
 Cd36
CD36 antigen
chr3_-_127837419 0.164 ENSMUST00000051737.6
 Ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr11_+_3983636 0.158 ENSMUST00000078757.1
 Gal3st1
galactose-3-O-sulfotransferase 1
chr2_-_119787504 0.145 ENSMUST00000110793.1
ENSMUST00000099529.2
ENSMUST00000048493.5
 Rpap1


RNA polymerase II associated protein 1


chr16_+_4741543 0.127 ENSMUST00000120232.1
 Hmox2
heme oxygenase (decycling) 2
chr5_-_137072254 0.116 ENSMUST00000077523.3
ENSMUST00000041388.4
 Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

chr10_-_53647080 0.105 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr9_-_32541589 0.097 ENSMUST00000016231.7
 Fli1
Friend leukemia integration 1
chr1_+_135729147 0.089 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr15_+_100038635 0.081 ENSMUST00000100203.3
 Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr11_+_3983704 0.081 ENSMUST00000063004.7
 Gal3st1
galactose-3-O-sulfotransferase 1
chr2_-_181599128 0.081 ENSMUST00000060173.8
 Samd10
sterile alpha motif domain containing 10
chr9_-_72111651 0.079 ENSMUST00000185117.1
 Tcf12
transcription factor 12
chr1_+_37997975 0.071 ENSMUST00000027252.7
 Eif5b
eukaryotic translation initiation factor 5B
chr13_-_97747373 0.071 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_+_134396320 0.069 ENSMUST00000105869.2
 Pafah2
platelet-activating factor acetylhydrolase 2
chr11_+_43474276 0.057 ENSMUST00000173002.1
ENSMUST00000057679.3
 C1qtnf2

C1q and tumor necrosis factor related protein 2

chr3_+_90476121 0.045 ENSMUST00000001042.8
 Ilf2
interleukin enhancer binding factor 2
chr18_-_74961252 0.044 ENSMUST00000066532.4
 Lipg
lipase, endothelial
chr12_+_8674224 0.037 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr7_+_127800604 0.009 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
 Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr4_+_109343029 0.008 ENSMUST00000030281.5
 Eps15
epidermal growth factor receptor pathway substrate 15
chrX_+_100767719 0.007 ENSMUST00000000901.6
ENSMUST00000113736.2
ENSMUST00000087984.4
 Dlg3


discs, large homolog 3 (Drosophila)


chr3_+_19957037 0.004 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
 Cp


ceruloplasmin



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.3 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.2 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:2000097 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.3 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.0 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 2.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling