Motif ID: Sox5_Sry
Z-value: 1.282
Transcription factors associated with Sox5_Sry:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Sox5 | ENSMUSG00000041540.10 | Sox5 |
Sry | ENSMUSG00000069036.3 | Sry |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Sox5 | mm10_v2_chr6_-_143947061_143947088 | 0.66 | 3.2e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.1 | 9.2 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
1.3 | 5.1 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
1.3 | 10.3 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
1.2 | 13.4 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.5 | 1.9 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
0.5 | 2.9 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
0.5 | 1.4 | GO:0097401 | synaptic vesicle lumen acidification(GO:0097401) |
0.5 | 1.9 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
0.5 | 2.8 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
0.4 | 2.4 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
0.4 | 1.2 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
0.4 | 1.6 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
0.4 | 3.2 | GO:0061368 | maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.4 | 1.1 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
0.3 | 3.1 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.3 | 2.0 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
0.3 | 1.3 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.3 | 2.7 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
0.3 | 0.9 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
0.3 | 1.9 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.3 | 0.9 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.3 | 3.5 | GO:0032808 | lacrimal gland development(GO:0032808) |
0.3 | 1.2 | GO:0045358 | negative regulation of interferon-beta biosynthetic process(GO:0045358) |
0.3 | 3.1 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.3 | 0.8 | GO:0021837 | motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465) |
0.3 | 2.3 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.3 | 0.8 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
0.2 | 0.7 | GO:0050904 | diapedesis(GO:0050904) |
0.2 | 1.9 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
0.2 | 0.9 | GO:1903028 | regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028) |
0.2 | 5.1 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.2 | 0.7 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
0.2 | 3.3 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.2 | 2.0 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.2 | 9.1 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.2 | 1.9 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
0.2 | 0.6 | GO:0003162 | atrioventricular node development(GO:0003162) |
0.2 | 3.7 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.2 | 0.8 | GO:0016240 | autophagosome docking(GO:0016240) |
0.2 | 0.6 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
0.2 | 0.6 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
0.2 | 1.6 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.2 | 1.0 | GO:0046684 | response to pyrethroid(GO:0046684) |
0.2 | 0.5 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) |
0.2 | 0.9 | GO:0048133 | NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728) |
0.2 | 0.5 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.2 | 0.7 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
0.2 | 0.9 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
0.2 | 0.2 | GO:0035441 | cell migration involved in vasculogenesis(GO:0035441) |
0.2 | 1.0 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
0.2 | 0.8 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.2 | 0.6 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
0.2 | 0.5 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
0.1 | 4.6 | GO:0030325 | adrenal gland development(GO:0030325) |
0.1 | 0.3 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.1 | 0.4 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
0.1 | 0.7 | GO:0042891 | antibiotic transport(GO:0042891) dipeptide transport(GO:0042938) |
0.1 | 0.7 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.1 | 0.4 | GO:0097278 | transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278) |
0.1 | 0.3 | GO:0051884 | regulation of anagen(GO:0051884) |
0.1 | 0.9 | GO:0035826 | rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476) |
0.1 | 0.5 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
0.1 | 1.4 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.1 | 1.5 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
0.1 | 0.6 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
0.1 | 0.6 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
0.1 | 1.3 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.1 | 0.4 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
0.1 | 1.4 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 0.3 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.1 | 0.4 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
0.1 | 0.8 | GO:0031642 | negative regulation of myelination(GO:0031642) negative regulation of excitatory postsynaptic potential(GO:0090394) |
0.1 | 2.6 | GO:0030204 | chondroitin sulfate metabolic process(GO:0030204) |
0.1 | 0.6 | GO:0021960 | anterior commissure morphogenesis(GO:0021960) |
0.1 | 0.2 | GO:0060160 | musculoskeletal movement, spinal reflex action(GO:0050883) negative regulation of dopamine receptor signaling pathway(GO:0060160) |
0.1 | 1.0 | GO:0097475 | motor neuron migration(GO:0097475) |
0.1 | 1.8 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
0.1 | 2.1 | GO:0001967 | suckling behavior(GO:0001967) |
0.1 | 2.5 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
0.1 | 0.5 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
0.1 | 1.0 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
0.1 | 0.3 | GO:0071492 | cellular response to UV-A(GO:0071492) |
0.1 | 0.2 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
0.1 | 0.7 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
0.1 | 0.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.1 | 0.5 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
0.1 | 0.9 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
0.1 | 1.2 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
0.1 | 2.9 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.1 | 0.4 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
0.1 | 0.3 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
0.1 | 0.1 | GO:0002053 | positive regulation of mesenchymal cell proliferation(GO:0002053) |
0.1 | 0.6 | GO:0070842 | aggresome assembly(GO:0070842) |
0.1 | 0.6 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.1 | 0.8 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.1 | 1.0 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
0.1 | 0.4 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
0.1 | 0.4 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
0.0 | 0.3 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
0.0 | 0.3 | GO:0019532 | oxalate transport(GO:0019532) |
0.0 | 0.2 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.0 | 0.5 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.0 | 0.9 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
0.0 | 0.2 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
0.0 | 0.1 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
0.0 | 0.8 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.0 | 0.7 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.0 | 1.3 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 0.2 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
0.0 | 0.4 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 0.2 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
0.0 | 0.2 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
0.0 | 0.3 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.0 | 0.4 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
0.0 | 0.1 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
0.0 | 0.1 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670) |
0.0 | 1.4 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.0 | 0.2 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
0.0 | 0.3 | GO:0046007 | regulation of germinal center formation(GO:0002634) negative regulation of activated T cell proliferation(GO:0046007) |
0.0 | 0.2 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.2 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.0 | 2.8 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
0.0 | 0.5 | GO:0001553 | luteinization(GO:0001553) |
0.0 | 0.1 | GO:0033030 | negative regulation of neutrophil apoptotic process(GO:0033030) |
0.0 | 0.1 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
0.0 | 0.1 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.0 | 0.1 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
0.0 | 0.1 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.0 | 0.6 | GO:0072348 | sulfur compound transport(GO:0072348) |
0.0 | 0.9 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.0 | 0.2 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.0 | 0.2 | GO:0007144 | female meiosis I(GO:0007144) |
0.0 | 0.1 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
0.0 | 0.1 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
0.0 | 0.6 | GO:0035329 | hippo signaling(GO:0035329) |
0.0 | 1.1 | GO:0045839 | negative regulation of mitotic nuclear division(GO:0045839) |
0.0 | 0.1 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
0.0 | 1.6 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.7 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.7 | GO:0021591 | ventricular system development(GO:0021591) |
0.0 | 0.9 | GO:0006284 | base-excision repair(GO:0006284) |
0.0 | 0.1 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.0 | 0.4 | GO:0008053 | mitochondrial fusion(GO:0008053) |
0.0 | 0.2 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.1 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.0 | 4.0 | GO:0006470 | protein dephosphorylation(GO:0006470) |
0.0 | 0.9 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
0.0 | 0.1 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.0 | 0.4 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
0.0 | 0.6 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
0.0 | 0.9 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 0.5 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
0.0 | 1.9 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
0.0 | 0.3 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
0.0 | 0.1 | GO:0010745 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) |
0.0 | 0.1 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.0 | 0.2 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 5.1 | GO:0031673 | H zone(GO:0031673) |
0.7 | 13.4 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.4 | 2.4 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.3 | 2.0 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
0.2 | 5.1 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.2 | 0.9 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
0.2 | 2.2 | GO:0001739 | sex chromatin(GO:0001739) |
0.2 | 0.6 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
0.2 | 1.7 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.2 | 0.9 | GO:1990130 | Iml1 complex(GO:1990130) |
0.2 | 1.4 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.1 | 0.7 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.1 | 2.3 | GO:1990635 | proximal dendrite(GO:1990635) |
0.1 | 2.3 | GO:0098839 | postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634) |
0.1 | 3.1 | GO:0031430 | M band(GO:0031430) |
0.1 | 0.5 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.1 | 0.8 | GO:0044305 | calyx of Held(GO:0044305) |
0.1 | 0.6 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.1 | 1.2 | GO:0044327 | dendritic spine head(GO:0044327) |
0.1 | 2.8 | GO:0071565 | nBAF complex(GO:0071565) |
0.1 | 0.5 | GO:0043198 | dendritic shaft(GO:0043198) |
0.1 | 13.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.1 | 1.4 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 0.3 | GO:0032437 | cuticular plate(GO:0032437) |
0.1 | 0.8 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 1.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.1 | 0.4 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.1 | 0.7 | GO:0097165 | nuclear stress granule(GO:0097165) |
0.1 | 0.8 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.1 | 1.9 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.1 | 1.0 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.1 | 0.4 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
0.0 | 0.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 0.6 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 3.5 | GO:0030425 | dendrite(GO:0030425) |
0.0 | 0.4 | GO:0070578 | micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578) |
0.0 | 0.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 2.0 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 1.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 2.2 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.4 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 0.2 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.0 | 1.5 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.3 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.0 | 0.6 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.6 | GO:0097386 | glial cell projection(GO:0097386) |
0.0 | 1.4 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 1.9 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 1.2 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.8 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.1 | GO:1990357 | terminal web(GO:1990357) |
0.0 | 0.1 | GO:0001520 | outer dense fiber(GO:0001520) |
0.0 | 0.5 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.0 | 0.1 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.0 | 0.7 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 1.4 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 13.2 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.0 | 0.9 | GO:0016234 | inclusion body(GO:0016234) |
0.0 | 0.4 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.3 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.4 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 2.5 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
0.0 | 0.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.1 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 1.1 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.2 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 3.1 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 1.7 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 1.3 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 0.8 | GO:0036126 | sperm flagellum(GO:0036126) |
0.0 | 0.7 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.2 | GO:0000346 | transcription export complex(GO:0000346) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.1 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.7 | 4.8 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.6 | 9.5 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.5 | 9.9 | GO:0030275 | LRR domain binding(GO:0030275) |
0.5 | 2.0 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
0.4 | 2.7 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.4 | 2.6 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
0.4 | 1.4 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.3 | 1.6 | GO:0043532 | angiostatin binding(GO:0043532) |
0.3 | 18.0 | GO:0030507 | spectrin binding(GO:0030507) |
0.3 | 1.2 | GO:0001093 | TFIIB-class transcription factor binding(GO:0001093) |
0.3 | 1.4 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.3 | 3.9 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.2 | 1.5 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.2 | 0.7 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
0.2 | 0.9 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
0.2 | 2.9 | GO:0038191 | neuropilin binding(GO:0038191) |
0.2 | 2.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.2 | 1.9 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.2 | 1.4 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.2 | 0.6 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
0.2 | 11.2 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.2 | 1.4 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.2 | 0.7 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
0.1 | 0.7 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.1 | 0.9 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
0.1 | 0.9 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.1 | 0.6 | GO:0008761 | UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) |
0.1 | 1.3 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 0.8 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.1 | 0.6 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
0.1 | 1.8 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.1 | 1.6 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.1 | 0.5 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
0.1 | 0.4 | GO:0035198 | miRNA binding(GO:0035198) |
0.1 | 0.8 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 3.0 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.1 | 0.8 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.1 | 0.4 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.1 | 0.4 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.1 | 2.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.1 | 2.0 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 0.7 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.9 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 0.1 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
0.1 | 0.4 | GO:0002135 | CTP binding(GO:0002135) |
0.1 | 0.5 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.1 | 0.2 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
0.1 | 0.4 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.1 | 14.2 | GO:0008017 | microtubule binding(GO:0008017) |
0.1 | 1.1 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.1 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.0 | 1.0 | GO:0031402 | sodium ion binding(GO:0031402) |
0.0 | 0.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 0.6 | GO:0050811 | GABA receptor binding(GO:0050811) inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.0 | 1.4 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.2 | GO:0019237 | centromeric DNA binding(GO:0019237) |
0.0 | 0.4 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 0.6 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.0 | 1.0 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.5 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.0 | 0.2 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.0 | 0.3 | GO:0035005 | lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.0 | 1.9 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 0.1 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.0 | 0.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.2 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.0 | 0.1 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.2 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.0 | 0.3 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 0.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.0 | 0.9 | GO:0043531 | ADP binding(GO:0043531) |
0.0 | 1.0 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 0.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.1 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.0 | 0.6 | GO:0042605 | peptide antigen binding(GO:0042605) |
0.0 | 0.4 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.1 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
0.0 | 0.2 | GO:0097153 | cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
0.0 | 0.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 3.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.8 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 1.0 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.0 | 0.1 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.0 | 0.4 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
0.0 | 1.3 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 5.7 | GO:0003779 | actin binding(GO:0003779) |
0.0 | 3.1 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 0.1 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 1.3 | GO:0008135 | translation factor activity, RNA binding(GO:0008135) |
0.0 | 0.3 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
0.0 | 0.4 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.0 | 0.3 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.0 | 1.8 | GO:0004386 | helicase activity(GO:0004386) |
0.0 | 0.1 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.0 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.2 | 10.2 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
0.1 | 5.5 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.1 | 7.0 | PID_FGF_PATHWAY | FGF signaling pathway |
0.1 | 4.8 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.1 | 3.3 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.1 | 1.1 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.1 | 0.5 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 0.2 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
0.0 | 0.5 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
0.0 | 2.3 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 1.2 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
0.0 | 0.6 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 1.8 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 1.2 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
0.0 | 2.9 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.4 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
0.0 | 1.1 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
0.0 | 0.8 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
0.0 | 1.0 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 1.2 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 0.5 | PID_RHOA_PATHWAY | RhoA signaling pathway |
0.0 | 0.7 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
0.0 | 0.6 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
0.0 | 1.3 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
0.0 | 0.1 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
0.0 | 0.3 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.0 | 0.1 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
0.0 | 0.3 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 13.4 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.2 | 9.2 | REACTOME_INTERFERON_GAMMA_SIGNALING | Genes involved in Interferon gamma signaling |
0.2 | 5.1 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
0.2 | 1.3 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.2 | 3.6 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.1 | 1.8 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
0.1 | 2.0 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.1 | 0.3 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.1 | 2.9 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.1 | 2.2 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.1 | 1.0 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.1 | 0.6 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.1 | 1.5 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.1 | 1.4 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.1 | 0.4 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.1 | 0.9 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.1 | 0.7 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
0.1 | 0.6 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.1 | 0.8 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 2.0 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.0 | 1.1 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.7 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.0 | 3.0 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.8 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.7 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 2.2 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
0.0 | 0.6 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.0 | 0.2 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.5 | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | Genes involved in Trafficking of AMPA receptors |
0.0 | 1.9 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 0.1 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 0.5 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 0.2 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.0 | 0.6 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
0.0 | 0.6 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 0.7 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.4 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |