Motif ID: Taf1

Z-value: 2.189


Transcription factors associated with Taf1:

Gene SymbolEntrez IDGene Name
Taf1 ENSMUSG00000031314.11 Taf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Taf1mm10_v2_chrX_+_101532734_1015327770.841.5e-05Click!


Activity profile for motif Taf1.

activity profile for motif Taf1


Sorted Z-values histogram for motif Taf1

Sorted Z-values for motif Taf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Taf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_73966329 4.748 ENSMUST00000114372.2
ENSMUST00000033761.6
 Hcfc1

host cell factor C1

chr2_+_30286406 3.898 ENSMUST00000138666.1
ENSMUST00000113634.2
 Nup188

nucleoporin 188

chr2_-_180709985 3.556 ENSMUST00000103057.1
ENSMUST00000103055.1
 Dido1

death inducer-obliterator 1

chr2_+_119047129 3.240 ENSMUST00000153300.1
ENSMUST00000028799.5
 Casc5

cancer susceptibility candidate 5

chr8_-_111259192 3.145 ENSMUST00000169020.1
ENSMUST00000003404.8
 Glg1

golgi apparatus protein 1

chr7_+_127511976 3.129 ENSMUST00000098025.4
 Srcap
Snf2-related CREBBP activator protein
chr3_-_84220853 3.126 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
 Trim2


tripartite motif-containing 2


chr5_+_23434435 3.114 ENSMUST00000094962.2
ENSMUST00000115128.1
 Kmt2e

lysine (K)-specific methyltransferase 2E

chr1_+_87403705 3.013 ENSMUST00000172736.1
 Gigyf2
GRB10 interacting GYF protein 2
chr7_+_59228743 2.975 ENSMUST00000107537.1
 Ube3a
ubiquitin protein ligase E3A
chr5_+_3928033 2.950 ENSMUST00000143365.1
 Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chrX_-_105929206 2.795 ENSMUST00000134381.1
ENSMUST00000154866.1
 Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr18_+_34220890 2.775 ENSMUST00000171187.1
 Apc
adenomatosis polyposis coli
chrX_-_105929333 2.765 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
 Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chr6_+_92092369 2.762 ENSMUST00000113463.1
 Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr14_-_31206666 2.747 ENSMUST00000165981.1
ENSMUST00000171735.1
 Nisch

nischarin

chrX_+_151803642 2.656 ENSMUST00000156616.2
 Huwe1
HECT, UBA and WWE domain containing 1
chr18_-_6241470 2.463 ENSMUST00000163210.1
 Kif5b
kinesin family member 5B
chr3_-_69004475 2.433 ENSMUST00000154741.1
ENSMUST00000148031.1
 Ift80

intraflagellar transport 80

chr1_-_166002613 2.412 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
 Pou2f1



POU domain, class 2, transcription factor 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 427 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 8.9 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.4 8.3 GO:0060009 Sertoli cell development(GO:0060009)
0.2 6.5 GO:0061157 mRNA destabilization(GO:0061157)
0.3 5.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 4.8 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.6 4.7 GO:0019046 release from viral latency(GO:0019046)
0.7 4.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.1 4.5 GO:0070829 heterochromatin maintenance(GO:0070829)
0.9 4.5 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.3 4.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
1.0 4.1 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
1.0 4.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.8 4.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 3.8 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.2 3.7 GO:0015693 magnesium ion transport(GO:0015693)
0.5 3.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 3.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 3.4 GO:0048520 positive regulation of behavior(GO:0048520)
1.1 3.3 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1 3.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 204 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 7.0 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
1.2 6.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 5.9 GO:1990635 proximal dendrite(GO:1990635)
0.0 5.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.3 5.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 5.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 4.8 GO:0035097 histone methyltransferase complex(GO:0035097)
1.1 4.4 GO:0044307 dendritic branch(GO:0044307)
0.2 4.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.5 4.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 4.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.4 3.9 GO:0097165 nuclear stress granule(GO:0097165)
0.1 3.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 3.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 3.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 3.5 GO:0035253 ciliary rootlet(GO:0035253)
0.5 3.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 3.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 3.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 3.3 GO:0033268 node of Ranvier(GO:0033268)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 245 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 10.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 9.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 7.5 GO:0008270 zinc ion binding(GO:0008270)
1.0 7.0 GO:0015616 DNA translocase activity(GO:0015616)
0.3 6.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 6.4 GO:0005516 calmodulin binding(GO:0005516)
0.1 6.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 6.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 6.1 GO:0035064 methylated histone binding(GO:0035064)
0.6 5.7 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 5.5 GO:0030507 spectrin binding(GO:0030507)
0.2 5.4 GO:0070064 proline-rich region binding(GO:0070064)
0.6 5.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.8 5.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 4.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 4.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
1.4 4.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.6 4.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 4.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.8 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 6.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 5.9 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 5.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 5.5 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 4.5 PID_INSULIN_PATHWAY Insulin Pathway
0.1 4.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.2 PID_ATM_PATHWAY ATM pathway
0.1 3.5 PID_LKB1_PATHWAY LKB1 signaling events
0.1 3.3 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 2.8 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 2.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 2.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 2.4 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 2.0 PID_ARF_3PATHWAY Arf1 pathway
0.2 1.8 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.8 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.8 PID_TXA2PATHWAY Thromboxane A2 receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 78 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 7.0 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 5.7 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 5.3 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.2 4.8 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 4.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 4.5 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.2 4.1 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 3.5 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 3.5 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 3.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.2 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.1 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.5 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.3 2.3 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 2.3 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.3 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse