Motif ID: Tbp

Z-value: 3.255


Transcription factors associated with Tbp:

Gene SymbolEntrez IDGene Name
Tbp ENSMUSG00000014767.10 Tbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbpmm10_v2_chr17_+_15499888_15499960-0.814.7e-05Click!


Activity profile for motif Tbp.

activity profile for motif Tbp


Sorted Z-values histogram for motif Tbp

Sorted Z-values for motif Tbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbp

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_87948666 22.320 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr7_-_103853199 18.507 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr1_-_138842429 14.753 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr13_+_21717626 12.983 ENSMUST00000091754.2
Hist1h3h
histone cluster 1, H3h
chr1_-_171196229 10.122 ENSMUST00000111332.1
Pcp4l1
Purkinje cell protein 4-like 1
chr13_+_23575753 9.437 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr1_+_109993982 9.432 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr7_-_142899985 9.314 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr7_-_137314394 9.035 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr13_-_21783391 8.448 ENSMUST00000099704.3
Hist1h3i
histone cluster 1, H3i
chr13_+_23581563 8.030 ENSMUST00000102968.1
Hist1h4d
histone cluster 1, H4d
chr13_+_23752267 8.013 ENSMUST00000091703.2
Hist1h3b
histone cluster 1, H3b
chr13_+_113035111 7.942 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr13_+_51846673 7.812 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr17_+_24720063 7.765 ENSMUST00000170715.1
ENSMUST00000054289.6
ENSMUST00000146867.1
Rps2


ribosomal protein S2


chr6_-_87981482 7.652 ENSMUST00000056403.5
H1fx
H1 histone family, member X
chr13_+_23544052 7.518 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr13_-_99900645 7.511 ENSMUST00000022150.6
Cartpt
CART prepropeptide
chr13_+_23763660 7.348 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr11_+_94936224 7.233 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr13_-_23745511 7.206 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr13_-_21750505 7.143 ENSMUST00000102983.1
Hist1h4k
histone cluster 1, H4k
chr7_-_4812351 7.087 ENSMUST00000079496.7
Ube2s
ubiquitin-conjugating enzyme E2S
chr13_-_23622502 6.609 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr12_+_3954943 6.587 ENSMUST00000020990.5
Pomc
pro-opiomelanocortin-alpha
chr11_+_120949053 6.546 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
Slc16a3



solute carrier family 16 (monocarboxylic acid transporters), member 3



chrX_-_162159717 6.214 ENSMUST00000087085.3
Nhs
Nance-Horan syndrome (human)
chr13_-_21780616 6.160 ENSMUST00000080511.2
Hist1h1b
histone cluster 1, H1b
chr19_-_53589067 6.157 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr6_-_136875794 6.132 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr8_-_110168204 5.934 ENSMUST00000003754.6
Calb2
calbindin 2
chr12_-_111672290 5.820 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr13_-_23934156 5.774 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr14_+_67745229 5.762 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr4_+_116685859 5.667 ENSMUST00000129315.1
ENSMUST00000106470.1
Prdx1

peroxiredoxin 1

chr17_-_34000257 5.538 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr13_-_23762378 5.403 ENSMUST00000091701.2
Hist1h3a
histone cluster 1, H3a
chr4_+_116685544 5.399 ENSMUST00000135573.1
ENSMUST00000151129.1
Prdx1

peroxiredoxin 1

chr6_-_125165707 5.242 ENSMUST00000118875.1
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr1_-_91413163 5.240 ENSMUST00000086851.1
Hes6
hairy and enhancer of split 6
chr10_+_88091070 4.946 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr13_-_21716143 4.932 ENSMUST00000091756.1
Hist1h2bl
histone cluster 1, H2bl
chr2_-_164857542 4.930 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr19_+_8888880 4.634 ENSMUST00000096251.3
1810009A15Rik
RIKEN cDNA 1810009A15 gene
chr13_+_23531044 4.632 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr17_-_33824346 4.616 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
Rps28




ribosomal protein S28




chr10_-_128626464 4.599 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr2_+_13573927 4.520 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr13_+_21716385 4.486 ENSMUST00000070124.3
Hist1h2ai
histone cluster 1, H2ai
chr11_+_3289168 4.435 ENSMUST00000134089.1
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr6_-_125165576 4.401 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr10_-_88605017 4.333 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr8_+_94179089 4.324 ENSMUST00000034215.6
Mt1
metallothionein 1
chr11_-_33163072 4.222 ENSMUST00000093201.6
ENSMUST00000101375.4
ENSMUST00000109354.3
ENSMUST00000075641.3
Npm1



nucleophosmin 1



chr10_-_40302186 4.211 ENSMUST00000099945.4
Amd1
S-adenosylmethionine decarboxylase 1
chr10_-_93589621 4.104 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr11_-_77725281 4.055 ENSMUST00000078623.4
Cryba1
crystallin, beta A1
chr5_-_77115145 4.021 ENSMUST00000081964.5
Hopx
HOP homeobox
chr11_-_31671863 4.012 ENSMUST00000058060.7
Bod1
biorientation of chromosomes in cell division 1
chr17_-_24251382 3.938 ENSMUST00000115390.3
Ccnf
cyclin F
chr13_-_21501418 3.934 ENSMUST00000044043.2
Gm11273
predicted gene 11273
chr8_+_84969767 3.901 ENSMUST00000109733.1
Prdx2
peroxiredoxin 2
chr4_-_3835595 3.890 ENSMUST00000138502.1
Rps20
ribosomal protein S20
chr4_-_133967296 3.759 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr13_-_21787218 3.751 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr13_-_23683941 3.705 ENSMUST00000171127.1
Hist1h2ac
histone cluster 1, H2ac
chr8_-_84969412 3.704 ENSMUST00000147812.1
Rnaseh2a
ribonuclease H2, large subunit
chr17_-_33955658 3.679 ENSMUST00000174609.2
ENSMUST00000008812.7
Rps18

ribosomal protein S18

chr7_-_45459839 3.654 ENSMUST00000094434.4
Ftl1
ferritin light chain 1
chr18_+_34625009 3.618 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr9_+_95637601 3.569 ENSMUST00000015498.8
Pcolce2
procollagen C-endopeptidase enhancer 2
chr5_-_99978914 3.561 ENSMUST00000112939.3
ENSMUST00000171786.1
ENSMUST00000072750.6
ENSMUST00000019128.8
ENSMUST00000172361.1
Hnrnpd




heterogeneous nuclear ribonucleoprotein D




chr3_-_33082004 3.552 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr7_+_35119285 3.539 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr4_-_116627478 3.524 ENSMUST00000081182.4
ENSMUST00000030457.5
Nasp

nuclear autoantigenic sperm protein (histone-binding)

chr2_-_119618455 3.515 ENSMUST00000123818.1
Oip5
Opa interacting protein 5
chr13_+_23684192 3.511 ENSMUST00000018246.4
Hist1h2bc
histone cluster 1, H2bc
chr11_+_3289880 3.493 ENSMUST00000110043.1
ENSMUST00000094471.3
Patz1

POZ (BTB) and AT hook containing zinc finger 1

chr8_+_84969587 3.475 ENSMUST00000109734.1
ENSMUST00000005292.8
Prdx2

peroxiredoxin 2

chr13_+_21735055 3.445 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr17_+_80944611 3.372 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr2_+_119618717 3.342 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chr1_-_134079114 3.248 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr5_+_135887905 3.245 ENSMUST00000005077.6
Hspb1
heat shock protein 1
chr4_-_132353605 3.244 ENSMUST00000155129.1
Rcc1
regulator of chromosome condensation 1
chr7_-_103843154 3.220 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr13_-_3893556 3.192 ENSMUST00000099946.4
Net1
neuroepithelial cell transforming gene 1
chr13_+_21787461 3.170 ENSMUST00000110473.2
ENSMUST00000102982.1
Hist1h2bp

histone cluster 1, H2bp

chr3_-_145649970 3.155 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr4_+_136143497 3.139 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr17_+_33824591 3.137 ENSMUST00000048249.6
Ndufa7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a)
chr10_+_80826656 3.136 ENSMUST00000060987.8
ENSMUST00000177850.1
ENSMUST00000180036.1
ENSMUST00000179172.1
Oaz1



ornithine decarboxylase antizyme 1



chr3_+_96268654 3.124 ENSMUST00000098843.2
Hist2h3b
histone cluster 2, H3b
chrX_+_36795642 3.123 ENSMUST00000016463.3
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr12_+_55598917 3.077 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr3_+_106113229 3.067 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chrX_-_74353575 3.065 ENSMUST00000114152.1
ENSMUST00000114153.1
ENSMUST00000015433.3
Lage3


L antigen family, member 3


chr17_-_14694223 2.937 ENSMUST00000170872.1
Thbs2
thrombospondin 2
chr11_-_100135928 2.920 ENSMUST00000107411.2
Krt15
keratin 15
chr17_+_23726336 2.838 ENSMUST00000024701.7
Pkmyt1
protein kinase, membrane associated tyrosine/threonine 1
chr2_+_91256144 2.824 ENSMUST00000154959.1
ENSMUST00000059566.4
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr8_+_84969824 2.813 ENSMUST00000125893.1
Prdx2
peroxiredoxin 2
chr16_-_36455378 2.802 ENSMUST00000068182.2
Stfa3
stefin A3
chr4_-_116627921 2.630 ENSMUST00000030456.7
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr5_-_125390176 2.614 ENSMUST00000156249.1
Ubc
ubiquitin C
chr6_-_24528013 2.607 ENSMUST00000023851.5
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr2_+_25180737 2.605 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr19_-_7039987 2.583 ENSMUST00000025918.7
Stip1
stress-induced phosphoprotein 1
chr15_+_80255184 2.569 ENSMUST00000109605.3
Atf4
activating transcription factor 4
chr2_-_93957040 2.562 ENSMUST00000148314.2
Gm13889
predicted gene 13889
chr6_+_135065651 2.560 ENSMUST00000050104.7
Gprc5a
G protein-coupled receptor, family C, group 5, member A
chr1_+_164048214 2.538 ENSMUST00000027874.5
Sele
selectin, endothelial cell
chr7_-_30612731 2.531 ENSMUST00000006476.4
Upk1a
uroplakin 1A
chr6_-_72958097 2.527 ENSMUST00000114049.1
Tmsb10
thymosin, beta 10
chr13_-_23571151 2.524 ENSMUST00000102969.3
Hist1h2ae
histone cluster 1, H2ae
chrX_+_74270812 2.494 ENSMUST00000008826.7
ENSMUST00000151702.1
ENSMUST00000074085.5
ENSMUST00000135690.1
Rpl10



ribosomal protein L10



chr16_-_89508313 2.473 ENSMUST00000056118.2
Krtap7-1
keratin associated protein 7-1
chr7_+_28810886 2.467 ENSMUST00000038572.8
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr9_-_78481724 2.467 ENSMUST00000042235.8
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr11_+_52232183 2.418 ENSMUST00000109072.1
Skp1a
S-phase kinase-associated protein 1A
chr11_+_99864476 2.416 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr16_+_90220742 2.407 ENSMUST00000023707.9
Sod1
superoxide dismutase 1, soluble
chr17_+_29032664 2.406 ENSMUST00000130216.1
Srsf3
serine/arginine-rich splicing factor 3
chr2_+_91255954 2.389 ENSMUST00000134699.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr18_+_34624621 2.363 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr11_-_31671727 2.357 ENSMUST00000109415.1
Bod1
biorientation of chromosomes in cell division 1
chr15_+_10952332 2.345 ENSMUST00000022853.8
ENSMUST00000110523.1
C1qtnf3

C1q and tumor necrosis factor related protein 3

chr11_+_46436925 2.331 ENSMUST00000152119.1
ENSMUST00000140027.1
ENSMUST00000020665.6
ENSMUST00000170928.1
ENSMUST00000109231.1
ENSMUST00000109232.3
ENSMUST00000128940.1
Med7






mediator complex subunit 7






chr5_+_64160207 2.324 ENSMUST00000101195.2
Tbc1d1
TBC1 domain family, member 1
chr5_+_135887988 2.300 ENSMUST00000111155.1
Hspb1
heat shock protein 1
chr10_+_96616998 2.293 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr11_+_6415443 2.268 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr2_-_25224653 2.259 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr2_-_51149100 2.256 ENSMUST00000154545.1
ENSMUST00000017288.2
Rnd3

Rho family GTPase 3

chr3_+_142765216 2.217 ENSMUST00000029938.8
Gtf2b
general transcription factor IIB
chr5_-_125389915 2.174 ENSMUST00000136312.1
Ubc
ubiquitin C
chr8_-_61591130 2.166 ENSMUST00000135439.1
ENSMUST00000121200.1
Palld

palladin, cytoskeletal associated protein

chr6_-_72958465 2.137 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chrM_+_7759 2.098 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr4_+_120666562 2.080 ENSMUST00000094814.4
Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr14_-_56062307 2.079 ENSMUST00000043249.8
Mcpt4
mast cell protease 4
chr11_-_115514374 2.058 ENSMUST00000021083.6
Hn1
hematological and neurological expressed sequence 1
chr4_+_43493345 2.057 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr14_+_69609068 2.012 ENSMUST00000022660.7
Loxl2
lysyl oxidase-like 2
chr11_+_6560183 2.008 ENSMUST00000109722.2
Ccm2
cerebral cavernous malformation 2
chr19_-_34255325 2.004 ENSMUST00000039631.8
Acta2
actin, alpha 2, smooth muscle, aorta
chrX_+_52791179 1.996 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr2_-_62483637 1.933 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr11_+_120598421 1.925 ENSMUST00000026128.3
Anapc11
anaphase promoting complex subunit 11
chr9_+_78175898 1.915 ENSMUST00000180974.1
C920006O11Rik
RIKEN cDNA C920006O11 gene
chr1_+_87183310 1.890 ENSMUST00000044533.8
Prss56
protease, serine 56
chr2_+_152736244 1.879 ENSMUST00000038368.8
ENSMUST00000109824.1
Id1

inhibitor of DNA binding 1

chr11_-_99024179 1.863 ENSMUST00000068031.7
Top2a
topoisomerase (DNA) II alpha
chr5_+_125389284 1.838 ENSMUST00000100700.2
Gm10382
predicted gene 10382
chr6_-_34317442 1.833 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr17_-_80207299 1.828 ENSMUST00000063417.9
Srsf7
serine/arginine-rich splicing factor 7
chr4_+_123282778 1.816 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
Pabpc4


poly(A) binding protein, cytoplasmic 4


chr15_-_60824942 1.811 ENSMUST00000100635.3
Fam84b
family with sequence similarity 84, member B
chr7_-_16259185 1.810 ENSMUST00000168818.1
C5ar1
complement component 5a receptor 1
chr8_-_124569696 1.802 ENSMUST00000063278.6
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr2_+_130576170 1.792 ENSMUST00000028764.5
Oxt
oxytocin
chr11_+_62551676 1.781 ENSMUST00000136938.1
Ubb
ubiquitin B
chr9_-_88522876 1.772 ENSMUST00000180563.2
ENSMUST00000183030.1
ENSMUST00000182232.1
Snhg5


small nucleolar RNA host gene 5


chrX_+_141475385 1.763 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5

collagen, type IV, alpha 5

chr19_+_9982694 1.754 ENSMUST00000025563.6
Fth1
ferritin heavy chain 1
chr12_-_110696289 1.743 ENSMUST00000021698.6
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr8_-_84846860 1.725 ENSMUST00000003912.6
Calr
calreticulin
chr5_+_139253489 1.721 ENSMUST00000138508.1
ENSMUST00000110878.1
Get4

golgi to ER traffic protein 4 homolog (S. cerevisiae)

chr19_+_8723478 1.696 ENSMUST00000180819.1
ENSMUST00000181422.1
Snhg1

small nucleolar RNA host gene (non-protein coding) 1

chr10_+_79704478 1.681 ENSMUST00000179781.1
Bsg
basigin
chr8_-_84969740 1.677 ENSMUST00000109736.2
ENSMUST00000140561.1
Rnaseh2a

ribonuclease H2, large subunit

chr10_+_79704499 1.595 ENSMUST00000067036.5
ENSMUST00000178383.1
Bsg

basigin

chr11_+_120598532 1.587 ENSMUST00000093140.4
Anapc11
anaphase promoting complex subunit 11
chr2_-_11603192 1.580 ENSMUST00000040314.5
Rbm17
RNA binding motif protein 17
chr2_+_167062934 1.571 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr8_+_58912257 1.523 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr3_-_106167564 1.518 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr19_-_3414464 1.508 ENSMUST00000025842.6
Gal
galanin
chr5_+_115559505 1.484 ENSMUST00000156359.1
ENSMUST00000152976.1
Rplp0

ribosomal protein, large, P0

chr5_+_115559467 1.450 ENSMUST00000086519.5
Rplp0
ribosomal protein, large, P0
chr4_+_86930691 1.417 ENSMUST00000164590.1
Acer2
alkaline ceramidase 2
chr10_+_79988584 1.410 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr4_+_152008803 1.404 ENSMUST00000097773.3
Klhl21
kelch-like 21
chr9_+_21723576 1.403 ENSMUST00000034713.7
Ldlr
low density lipoprotein receptor
chr5_+_90903864 1.403 ENSMUST00000075433.6
Cxcl2
chemokine (C-X-C motif) ligand 2
chr9_+_44334685 1.386 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chr6_+_72598475 1.385 ENSMUST00000070597.6
ENSMUST00000176364.1
ENSMUST00000176168.1
Retsat


retinol saturase (all trans retinol 13,14 reductase)


chr17_-_35074485 1.374 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr13_+_23574381 1.373 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr4_+_127021311 1.372 ENSMUST00000030623.7
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr12_+_108851122 1.366 ENSMUST00000057026.8
Slc25a47
solute carrier family 25, member 47
chr5_-_114823460 1.346 ENSMUST00000140374.1
ENSMUST00000100850.4
Gm20499
2610524H06Rik
predicted gene 20499
RIKEN cDNA 2610524H06 gene
chr6_+_4747306 1.310 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr8_+_4349588 1.286 ENSMUST00000110982.1
ENSMUST00000024004.7
Ccl25

chemokine (C-C motif) ligand 25

chr2_-_26640230 1.275 ENSMUST00000181621.1
ENSMUST00000180659.1
Snhg7

small nucleolar RNA host gene (non-protein coding) 7

chr2_-_86347764 1.240 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr13_+_23571382 1.225 ENSMUST00000079251.5
Hist1h2bg
histone cluster 1, H2bg
chr3_-_59262825 1.205 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr15_+_3270767 1.178 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr11_+_52232009 1.164 ENSMUST00000037324.5
ENSMUST00000166537.1
Skp1a

S-phase kinase-associated protein 1A


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 21.7 GO:0015671 oxygen transport(GO:0015671)
3.0 14.8 GO:0035262 gonad morphogenesis(GO:0035262)
2.6 10.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.5 7.5 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
2.5 77.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
2.4 7.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
2.3 9.3 GO:0042414 epinephrine metabolic process(GO:0042414)
2.2 6.6 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
1.7 22.3 GO:0042573 retinoic acid metabolic process(GO:0042573)
1.4 5.8 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
1.4 4.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407)
1.4 4.2 GO:0006597 spermine biosynthetic process(GO:0006597)
1.4 5.5 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
1.3 3.9 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.2 4.9 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.2 4.9 GO:0042360 vitamin E metabolic process(GO:0042360)
1.2 3.6 GO:1901355 response to rapamycin(GO:1901355)
1.2 20.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
1.1 7.4 GO:0016584 nucleosome positioning(GO:0016584)
1.0 7.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.0 5.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.9 5.5 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.9 4.5 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.9 5.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.9 10.7 GO:0002227 innate immune response in mucosa(GO:0002227)
0.9 4.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.9 4.3 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.8 5.8 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.8 2.4 GO:0019401 alditol biosynthetic process(GO:0019401)
0.8 3.2 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.8 3.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.8 7.8 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.8 1.5 GO:0051795 positive regulation of catagen(GO:0051795)
0.7 4.0 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.7 6.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.6 7.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.6 2.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.6 3.8 GO:2000210 positive regulation of anoikis(GO:2000210)
0.6 1.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.6 1.8 GO:1902022 ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of activation of Janus kinase activity(GO:0010533) L-lysine transport(GO:1902022)
0.6 1.8 GO:0042713 sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455)
0.6 2.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.6 3.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.6 1.7 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.5 3.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.5 3.8 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.5 1.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.5 1.4 GO:0043031 regulation of phosphatidylcholine catabolic process(GO:0010899) positive regulation of lipoprotein particle clearance(GO:0010986) negative regulation of macrophage activation(GO:0043031) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) regulation of microglial cell activation(GO:1903978)
0.5 1.9 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) female meiosis chromosome separation(GO:0051309)
0.5 3.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.4 2.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.4 3.5 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.4 3.5 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.4 31.5 GO:0006334 nucleosome assembly(GO:0006334)
0.4 1.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.4 2.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 2.6 GO:0021886 female meiosis I(GO:0007144) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.4 1.9 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.4 1.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.4 1.1 GO:1903225 regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.0 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 1.0 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.3 6.0 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 1.3 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.3 2.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.3 1.9 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.3 1.1 GO:1903416 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) response to glycoside(GO:1903416)
0.3 3.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.3 2.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 5.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 2.5 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.2 3.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.2 2.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 4.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 3.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 2.0 GO:0046688 response to copper ion(GO:0046688)
0.2 3.1 GO:0061756 leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.2 1.7 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 0.4 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.2 3.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2 1.4 GO:0042572 retinol metabolic process(GO:0042572)
0.2 3.2 GO:0051451 myoblast migration(GO:0051451)
0.2 2.0 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.2 3.8 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 6.4 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 3.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 2.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 3.9 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.8 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 5.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 3.1 GO:0030903 notochord development(GO:0030903)
0.1 2.3 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 4.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.9 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.1 0.3 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 3.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 6.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 2.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.5 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 1.4 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 7.7 GO:0006342 chromatin silencing(GO:0006342)
0.1 2.5 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.1 2.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 2.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 3.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 4.6 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 1.4 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 1.4 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.5 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 1.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 2.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 2.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 1.8 GO:0061515 myeloid cell development(GO:0061515)
0.0 4.1 GO:0048754 branching morphogenesis of an epithelial tube(GO:0048754)
0.0 1.2 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 3.1 GO:0008033 tRNA processing(GO:0008033)
0.0 1.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 2.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.0 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 3.0 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.7 GO:0043627 response to estrogen(GO:0043627)
0.0 2.2 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 2.8 GO:0072659 protein localization to plasma membrane(GO:0072659)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
2.5 83.9 GO:0000788 nuclear nucleosome(GO:0000788)
2.4 7.2 GO:0005584 collagen type I trimer(GO:0005584)
1.5 11.9 GO:0005833 hemoglobin complex(GO:0005833)
1.4 9.6 GO:0097452 GAIT complex(GO:0097452)
1.2 3.5 GO:0036488 CHOP-C/EBP complex(GO:0036488)
1.1 4.5 GO:0045098 type III intermediate filament(GO:0045098)
0.9 5.5 GO:0097512 cardiac myofibril(GO:0097512)
0.9 5.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.9 3.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.9 33.6 GO:0000786 nucleosome(GO:0000786)
0.8 4.1 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.7 4.3 GO:0005859 muscle myosin complex(GO:0005859)
0.7 5.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.6 2.6 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.5 2.7 GO:0001652 granular component(GO:0001652)
0.5 3.1 GO:0071817 MMXD complex(GO:0071817)
0.5 3.6 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.5 2.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.5 24.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.5 5.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.5 1.8 GO:0097454 Schwann cell microvillus(GO:0097454)
0.4 11.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.4 10.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 1.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 1.0 GO:0036128 CatSper complex(GO:0036128)
0.3 2.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 1.4 GO:0097443 sorting endosome(GO:0097443)
0.3 1.1 GO:0032021 NELF complex(GO:0032021)
0.2 1.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 3.5 GO:0044754 autolysosome(GO:0044754)
0.2 2.3 GO:0045298 tubulin complex(GO:0045298)
0.2 1.7 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 2.9 GO:0031091 platelet alpha granule(GO:0031091)
0.2 5.3 GO:0005921 gap junction(GO:0005921)
0.2 1.4 GO:0005827 polar microtubule(GO:0005827)
0.2 1.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.9 GO:0001533 cornified envelope(GO:0001533)
0.2 3.5 GO:0010369 chromocenter(GO:0010369)
0.2 3.3 GO:0002080 acrosomal membrane(GO:0002080)
0.2 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 0.8 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 2.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.4 GO:0031045 dense core granule(GO:0031045)
0.1 2.5 GO:0045120 pronucleus(GO:0045120)
0.1 5.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 5.4 GO:0005882 intermediate filament(GO:0005882)
0.1 6.0 GO:0005871 kinesin complex(GO:0005871)
0.1 6.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 3.3 GO:0005876 spindle microtubule(GO:0005876)
0.1 17.9 GO:0043209 myelin sheath(GO:0043209)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 4.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 6.2 GO:0000793 condensed chromosome(GO:0000793)
0.1 2.2 GO:0002102 podosome(GO:0002102)
0.0 6.4 GO:0000776 kinetochore(GO:0000776)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.3 GO:0005581 collagen trimer(GO:0005581)
0.0 7.2 GO:0030141 secretory granule(GO:0030141)
0.0 7.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.8 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 1.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 30.9 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.3 GO:0031902 late endosome membrane(GO:0031902)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 21.7 GO:0005344 oxygen transporter activity(GO:0005344)
3.7 22.3 GO:0019841 retinol binding(GO:0019841)
3.2 9.6 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
2.2 6.6 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
2.1 21.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.9 9.3 GO:0035240 dopamine binding(GO:0035240)
1.5 5.8 GO:0004111 creatine kinase activity(GO:0004111)
1.4 66.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
1.1 4.5 GO:1990254 keratin filament binding(GO:1990254)
1.1 4.2 GO:0019808 polyamine binding(GO:0019808)
0.9 6.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.9 4.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.8 7.4 GO:0032564 dATP binding(GO:0032564)
0.8 3.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.8 5.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.7 3.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.6 4.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.6 1.8 GO:0004875 complement receptor activity(GO:0004875)
0.6 2.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5 7.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.5 1.4 GO:0071633 dihydroceramidase activity(GO:0071633)
0.5 4.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.5 1.9 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.4 5.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.4 5.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.4 1.5 GO:0004966 galanin receptor activity(GO:0004966)
0.4 1.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4 1.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 1.0 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 2.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 3.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.3 1.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.3 1.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.3 7.1 GO:0097602 cullin family protein binding(GO:0097602)
0.3 3.5 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.2 2.5 GO:1990715 mRNA CDS binding(GO:1990715)
0.2 7.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 3.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 1.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 6.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 2.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 3.3 GO:0005537 mannose binding(GO:0005537)
0.2 2.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 0.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 5.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.8 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 2.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 4.7 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 36.7 GO:0042393 histone binding(GO:0042393)
0.2 5.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 3.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 7.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 1.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 3.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 23.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.5 GO:0016151 nickel cation binding(GO:0016151)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 4.3 GO:0005507 copper ion binding(GO:0005507)
0.1 1.9 GO:0070628 proteasome binding(GO:0070628)
0.1 3.6 GO:0016504 peptidase activator activity(GO:0016504)
0.1 1.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 3.1 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.0 GO:0051861 glycolipid binding(GO:0051861)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 6.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.7 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 4.8 GO:0002020 protease binding(GO:0002020)
0.0 3.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 2.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 3.3 GO:0005506 iron ion binding(GO:0005506)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 1.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 2.5 GO:0008201 heparin binding(GO:0008201)
0.0 1.9 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.7 GO:0051087 chaperone binding(GO:0051087)
0.0 1.4 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 7.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 7.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 2.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0005179 hormone activity(GO:0005179)
0.0 3.3 GO:0008017 microtubule binding(GO:0008017)
0.0 2.5 GO:0004930 G-protein coupled receptor activity(GO:0004930)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 14.9 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 6.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.3 9.8 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.3 14.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.3 3.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.3 5.8 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.2 7.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 12.3 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.2 12.1 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 15.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 4.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 6.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 3.1 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 3.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 7.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 2.9 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.1 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.1 1.4 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 PID_ATM_PATHWAY ATM pathway
0.0 2.5 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 3.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.8 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 3.2 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.3 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.1 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.9 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 107.9 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
1.9 5.8 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
1.3 6.6 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
1.3 20.9 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.8 9.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.7 6.5 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 7.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.5 3.1 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.5 4.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5 24.5 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4 4.9 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 4.1 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 8.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.3 2.8 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.3 7.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 4.8 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.3 2.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 9.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 9.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 6.0 REACTOME_KINESINS Genes involved in Kinesins
0.2 2.8 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 3.5 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 3.3 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 9.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 8.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 1.4 REACTOME_LIPOPROTEIN_METABOLISM Genes involved in Lipoprotein metabolism
0.1 4.2 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ Genes involved in Cleavage of Growing Transcript in the Termination Region
0.1 5.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 3.1 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 5.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 0.8 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 0.8 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.0 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.1 10.5 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 5.5 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 2.2 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 1.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.1 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 7.1 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.5 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 2.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.9 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 1.4 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives