Motif ID: Tbx19

Z-value: 0.676


Transcription factors associated with Tbx19:

Gene SymbolEntrez IDGene Name
Tbx19 ENSMUSG00000026572.5 Tbx19



Activity profile for motif Tbx19.

activity profile for motif Tbx19


Sorted Z-values histogram for motif Tbx19

Sorted Z-values for motif Tbx19



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx19

PNG image of the network

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Top targets:


Showing 1 to 20 of 109 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_+_897782 1.640 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr14_+_115042752 1.449 ENSMUST00000134140.2
 Mir17hg
Mir17 host gene 1 (non-protein coding)
chr17_-_35027909 1.441 ENSMUST00000040151.2
 Sapcd1
suppressor APC domain containing 1
chr10_-_86011833 1.036 ENSMUST00000105304.1
ENSMUST00000061699.5
 Bpifc

BPI fold containing family C

chr6_-_119467210 0.973 ENSMUST00000118120.1
 Wnt5b
wingless-related MMTV integration site 5B
chr11_+_101468164 0.966 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr9_+_15520830 0.900 ENSMUST00000178999.1
 Smco4
single-pass membrane protein with coiled-coil domains 4
chr9_-_21760275 0.859 ENSMUST00000098942.4
 Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr16_-_45844303 0.826 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr4_+_3940747 0.818 ENSMUST00000119403.1
 Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr1_+_156838915 0.759 ENSMUST00000111720.1
 Angptl1
angiopoietin-like 1
chr19_+_5474681 0.708 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
 Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr15_-_98728120 0.659 ENSMUST00000003445.6
 Fkbp11
FK506 binding protein 11
chr3_-_97610156 0.557 ENSMUST00000029730.4
 Chd1l
chromodomain helicase DNA binding protein 1-like
chr2_-_132253227 0.520 ENSMUST00000028817.6
 Pcna
proliferating cell nuclear antigen
chr13_-_23562369 0.508 ENSMUST00000105107.1
 Hist1h3e
histone cluster 1, H3e
chr17_+_6978860 0.508 ENSMUST00000089119.5
ENSMUST00000179728.1
 Rnaset2b

ribonuclease T2B

chr3_+_94693556 0.484 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
 Selenbp2



selenium binding protein 2



chr11_-_60046477 0.462 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
 Pemt


phosphatidylethanolamine N-methyltransferase


chr4_+_136347286 0.453 ENSMUST00000140052.2
 9130020K20Rik
RIKEN cDNA 9130020K20 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 0.5 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 0.5 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.4 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 0.4 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.4 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.4 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.3 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.3 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.1 0.3 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.3 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.8 GO:0045180 basal cortex(GO:0045180)
0.2 0.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0000802 transverse filament(GO:0000802)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0033093 multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.6 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 0.5 GO:0032139 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.1 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.5 GO:0008430 selenium binding(GO:0008430)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.3 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 0.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.3 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 0.5 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters