---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_26229707	8.726	ENSMUST00000060716.5 ENSMUST00000164660.1	Samd3	sterile alpha motif domain containing 3
chr1_-_138847579	5.686	ENSMUST00000093486.3 ENSMUST00000046870.6	Lhx9	LIM homeobox protein 9
chr2_+_164562579	4.294	ENSMUST00000017867.3 ENSMUST00000109344.2 ENSMUST00000109345.2	Wfdc2	WAP four-disulfide core domain 2
chr17_+_29093763	3.632	ENSMUST00000023829.6	Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)
chr10_-_92162753	3.513	ENSMUST00000182197.1	Rmst	rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr2_-_57114970	3.489	ENSMUST00000028166.2	Nr4a2	nuclear receptor subfamily 4, group A, member 2
chr1_+_6730051	3.286	ENSMUST00000043578.6 ENSMUST00000131467.1 ENSMUST00000150761.1 ENSMUST00000151281.1	St18	suppression of tumorigenicity 18
chr2_-_13011747	3.276	ENSMUST00000061545.5	C1ql3	C1q-like 3
chr9_-_43239816	3.121	ENSMUST00000034512.5	Oaf	OAF homolog (Drosophila)
chr11_-_94507337	2.568	ENSMUST00000040692.8	Mycbpap	MYCBP associated protein
chr10_+_4710119	2.498	ENSMUST00000105588.1 ENSMUST00000105589.1	Esr1	estrogen receptor 1 (alpha)
chr10_-_120899067	2.367	ENSMUST00000092143.5	Msrb3	methionine sulfoxide reductase B3
chr6_-_94700137	2.352	ENSMUST00000101126.2 ENSMUST00000032105.4	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1
chr4_-_35845204	2.227	ENSMUST00000164772.1 ENSMUST00000065173.2	Lingo2	leucine rich repeat and Ig domain containing 2
chr1_+_132316112	2.116	ENSMUST00000082125.5 ENSMUST00000072177.7	Nuak2	NUAK family, SNF1-like kinase, 2
chr10_+_56377300	2.033	ENSMUST00000068581.7	Gja1	gap junction protein, alpha 1
chr1_+_6730135	1.935	ENSMUST00000155921.1	St18	suppression of tumorigenicity 18
chr11_-_84068357	1.926	ENSMUST00000100705.4	Dusp14	dual specificity phosphatase 14
chr6_+_7555053	1.897	ENSMUST00000090679.2 ENSMUST00000184986.1	Tac1	tachykinin 1
chr7_-_28302238	1.895	ENSMUST00000108315.3	Dll3	delta-like 3 (Drosophila)
chr4_+_125490688	1.758	ENSMUST00000030676.7	Grik3	glutamate receptor, ionotropic, kainate 3
chr11_-_84068766	1.731	ENSMUST00000018792.5	Dusp14	dual specificity phosphatase 14
chr14_+_62292475	1.679	ENSMUST00000166879.1	Rnaseh2b	ribonuclease H2, subunit B
chr12_+_3891728	1.607	ENSMUST00000172689.1 ENSMUST00000111186.1	Dnmt3a	DNA methyltransferase 3A
chr4_-_134018829	1.507	ENSMUST00000051674.2	Lin28a	lin-28 homolog A (C. elegans)
chr17_-_70849644	1.451	ENSMUST00000134654.1 ENSMUST00000172229.1 ENSMUST00000127719.1	Tgif1	TGFB-induced factor homeobox 1
chrX_+_142681398	1.273	ENSMUST00000112889.1 ENSMUST00000101198.2 ENSMUST00000112891.1 ENSMUST00000087333.2	Tmem164	transmembrane protein 164
chr1_+_153665274	1.264	ENSMUST00000152114.1 ENSMUST00000111812.1	Rgs8	regulator of G-protein signaling 8
chr6_-_127769427	1.255	ENSMUST00000032500.8	Prmt8	protein arginine N-methyltransferase 8
chr4_-_132510493	1.220	ENSMUST00000030724.8	Sesn2	sestrin 2
chr16_-_95459245	1.157	ENSMUST00000176345.1 ENSMUST00000121809.2 ENSMUST00000118113.1 ENSMUST00000122199.1	Erg	avian erythroblastosis virus E-26 (v-ets) oncogene related
chrM_+_8600	1.079	ENSMUST00000082409.1	mt-Co3	mitochondrially encoded cytochrome c oxidase III
chr1_+_153665666	1.077	ENSMUST00000111814.1 ENSMUST00000111810.1	Rgs8	regulator of G-protein signaling 8
chr12_+_55598917	1.043	ENSMUST00000051857.3	Insm2	insulinoma-associated 2
chr8_+_45885479	1.020	ENSMUST00000034053.5	Pdlim3	PDZ and LIM domain 3
chr3_-_154328634	1.010	ENSMUST00000167744.1	Lhx8	LIM homeobox protein 8
chr3_+_96629919	1.008	ENSMUST00000048915.6	Rbm8a	RNA binding motif protein 8a
chr8_+_106870827	0.996	ENSMUST00000176144.1 ENSMUST00000175987.1	Has3	hyaluronan synthase 3
chr4_-_123750236	0.935	ENSMUST00000102636.3	Akirin1	akirin 1
chr2_-_148046896	0.934	ENSMUST00000172928.1 ENSMUST00000047315.3	Foxa2	forkhead box A2
chr1_+_164115264	0.916	ENSMUST00000162746.1	Selp	selectin, platelet
chr2_+_27079371	0.912	ENSMUST00000091233.6	Adamtsl2	ADAMTS-like 2
chr1_+_131970589	0.896	ENSMUST00000027695.6	Slc45a3	solute carrier family 45, member 3
chrM_+_9452	0.881	ENSMUST00000082411.1	mt-Nd3	mitochondrially encoded NADH dehydrogenase 3
chr2_-_148045891	0.803	ENSMUST00000109964.1	Foxa2	forkhead box A2
chr2_+_20519776	0.787	ENSMUST00000114604.2 ENSMUST00000066509.3	Etl4	enhancer trap locus 4
chr4_-_42168603	0.774	ENSMUST00000098121.3	Gm13305	predicted gene 13305
chr15_-_98831498	0.770	ENSMUST00000168846.1	Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr7_-_141443989	0.765	ENSMUST00000026580.5	Lrdd	leucine-rich and death domain containing
chr3_+_40950631	0.763	ENSMUST00000048490.6	Larp1b	La ribonucleoprotein domain family, member 1B
chr12_-_31634592	0.756	ENSMUST00000020979.7 ENSMUST00000177962.1	Bcap29	B cell receptor associated protein 29
chr1_+_153665587	0.750	ENSMUST00000147700.1	Rgs8	regulator of G-protein signaling 8
chr1_-_105356658	0.746	ENSMUST00000058688.5 ENSMUST00000172299.1	Rnf152	ring finger protein 152
chr1_+_153665627	0.739	ENSMUST00000147482.1	Rgs8	regulator of G-protein signaling 8
chr9_-_69760924	0.685	ENSMUST00000071281.4	Foxb1	forkhead box B1
chr18_-_46212595	0.664	ENSMUST00000037011.4	Trim36	tripartite motif-containing 36
chr3_-_10208569	0.659	ENSMUST00000029041.4	Fabp4	fatty acid binding protein 4, adipocyte
chrX_+_100730178	0.617	ENSMUST00000113744.1	Gdpd2	glycerophosphodiester phosphodiesterase domain containing 2
chr6_+_50110837	0.616	ENSMUST00000167628.1	Mpp6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr7_-_30563184	0.556	ENSMUST00000043898.6	Psenen	presenilin enhancer 2 homolog (C. elegans)
chr11_-_117969176	0.548	ENSMUST00000054002.3	Socs3	suppressor of cytokine signaling 3
chr10_-_35711891	0.540	ENSMUST00000080898.2	Amd2	S-adenosylmethionine decarboxylase 2
chrX_-_53269020	0.536	ENSMUST00000114838.1	Fam122b	family with sequence similarity 122, member B
chr4_+_41760454	0.532	ENSMUST00000108040.1	Il11ra1	interleukin 11 receptor, alpha chain 1
chr10_-_128211788	0.527	ENSMUST00000061995.8	Spryd4	SPRY domain containing 4
chr4_+_117849361	0.518	ENSMUST00000163288.1	Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr4_-_117156144	0.517	ENSMUST00000102696.4	Rps8	ribosomal protein S8
chrX_+_100729917	0.508	ENSMUST00000019503.7	Gdpd2	glycerophosphodiester phosphodiesterase domain containing 2
chr19_+_6057925	0.504	ENSMUST00000179142.1	Fau	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr3_-_75556759	0.494	ENSMUST00000162138.1 ENSMUST00000029424.5 ENSMUST00000161137.1	Pdcd10	programmed cell death 10
chr10_+_80930071	0.480	ENSMUST00000015456.8	Gadd45b	growth arrest and DNA-damage-inducible 45 beta
chr16_-_56024628	0.480	ENSMUST00000119981.1 ENSMUST00000096021.3	Pcnp	PEST proteolytic signal containing nuclear protein
chrX_-_152016269	0.474	ENSMUST00000026288.4	Ribc1	RIB43A domain with coiled-coils 1
chrM_+_7759	0.473	ENSMUST00000082407.1 ENSMUST00000082408.1	mt-Atp8 mt-Atp6	mitochondrially encoded ATP synthase 8 mitochondrially encoded ATP synthase 6
chr7_-_114117761	0.470	ENSMUST00000069449.5	Rras2	related RAS viral (r-ras) oncogene homolog 2
chr19_+_8617991	0.453	ENSMUST00000010250.2	Slc22a6	solute carrier family 22 (organic anion transporter), member 6
chr2_-_25272380	0.446	ENSMUST00000028342.6	Ssna1	Sjogren's syndrome nuclear autoantigen 1
chr19_+_6057888	0.436	ENSMUST00000043074.5 ENSMUST00000178310.1	Fau	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr16_-_84835484	0.435	ENSMUST00000114191.1	Atp5j	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr16_+_19028232	0.428	ENSMUST00000074116.4	Gm10088	predicted gene 10088
chr5_-_24601961	0.427	ENSMUST00000030791.7	Smarcd3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr13_-_89742490	0.426	ENSMUST00000109546.2	Vcan	versican
chr1_-_174921813	0.424	ENSMUST00000055294.3	Grem2	gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr3_+_75557530	0.422	ENSMUST00000161776.1 ENSMUST00000029423.8	Serpini1	serine (or cysteine) peptidase inhibitor, clade I, member 1
chr3_+_51415986	0.419	ENSMUST00000029303.7	Naa15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr10_-_85916902	0.408	ENSMUST00000037646.7	Prdm4	PR domain containing 4
chr9_+_35421541	0.407	ENSMUST00000119129.2	Cdon	cell adhesion molecule-related/down-regulated by oncogenes
chr19_+_20601958	0.406	ENSMUST00000087638.3	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1
chr9_-_21073494	0.401	ENSMUST00000010348.5	Fdx1l	ferredoxin 1-like
chr1_+_74236479	0.393	ENSMUST00000113820.2 ENSMUST00000006467.7 ENSMUST00000113819.1	Arpc2	actin related protein 2/3 complex, subunit 2
chr9_-_13818665	0.393	ENSMUST00000150893.1 ENSMUST00000124883.1	Cep57	centrosomal protein 57
chr16_-_9994921	0.380	ENSMUST00000115835.1	Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr19_+_55894508	0.374	ENSMUST00000142291.1	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box
chr7_+_18884679	0.338	ENSMUST00000032573.6	Pglyrp1	peptidoglycan recognition protein 1
chr11_+_98348404	0.326	ENSMUST00000078694.6	Ppp1r1b	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr2_+_138278481	0.325	ENSMUST00000075410.4	Btbd3	BTB (POZ) domain containing 3
chr2_+_54436317	0.319	ENSMUST00000112636.1 ENSMUST00000112635.1 ENSMUST00000112634.1	Galnt13	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr1_+_170214826	0.317	ENSMUST00000159201.1 ENSMUST00000055830.1	4930500M09Rik	RIKEN cDNA 4930500M09 gene
chr12_+_78861693	0.308	ENSMUST00000071230.7	Eif2s1	eukaryotic translation initiation factor 2, subunit 1 alpha
chr3_+_102734496	0.304	ENSMUST00000029451.5	Tspan2	tetraspanin 2
chr18_+_60963517	0.302	ENSMUST00000115295.2 ENSMUST00000039904.6	Camk2a	calcium/calmodulin-dependent protein kinase II alpha
chr7_-_45830776	0.286	ENSMUST00000107723.2 ENSMUST00000131384.1	Grwd1	glutamate-rich WD repeat containing 1
chr1_-_87394721	0.281	ENSMUST00000113212.3	Kcnj13	potassium inwardly-rectifying channel, subfamily J, member 13
chr19_-_6057736	0.269	ENSMUST00000007482.6	Mrpl49	mitochondrial ribosomal protein L49
chr15_+_10952332	0.263	ENSMUST00000022853.8 ENSMUST00000110523.1	C1qtnf3	C1q and tumor necrosis factor related protein 3
chr2_-_30178422	0.262	ENSMUST00000100220.4 ENSMUST00000179795.1	D2Wsu81e	DNA segment, Chr 2, Wayne State University 81, expressed
chr12_-_56345862	0.260	ENSMUST00000021416.7	Mbip	MAP3K12 binding inhibitory protein 1
chrX_+_42150672	0.251	ENSMUST00000069619.7	Stag2	stromal antigen 2
chr9_+_15239045	0.248	ENSMUST00000034413.6	Vstm5	V-set and transmembrane domain containing 5
chr11_-_22286795	0.246	ENSMUST00000109563.2 ENSMUST00000180360.1	Ehbp1	EH domain binding protein 1
chr5_-_24329556	0.245	ENSMUST00000115098.2	Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr4_+_117849193	0.234	ENSMUST00000132043.2 ENSMUST00000169990.1	Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr19_+_21272276	0.225	ENSMUST00000025659.4	Zfand5	zinc finger, AN1-type domain 5
chr8_+_122476143	0.222	ENSMUST00000116412.1	Ctu2	cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr4_+_11191354	0.220	ENSMUST00000170901.1	Ccne2	cyclin E2
chr15_+_80623499	0.214	ENSMUST00000043149.7	Grap2	GRB2-related adaptor protein 2
chr6_+_61180313	0.213	ENSMUST00000126214.1	Ccser1	coiled-coil serine rich 1
chr10_-_86705485	0.212	ENSMUST00000020238.7	Hsp90b1	heat shock protein 90, beta (Grp94), member 1
chrX_+_101383726	0.210	ENSMUST00000119190.1	Gjb1	gap junction protein, beta 1
chr15_-_10470490	0.199	ENSMUST00000136591.1	Dnajc21	DnaJ (Hsp40) homolog, subfamily C, member 21
chr13_+_93304066	0.195	ENSMUST00000109493.1	Homer1	homer homolog 1 (Drosophila)
chr19_+_4097392	0.190	ENSMUST00000174514.1 ENSMUST00000174149.1	Cdk2ap2	CDK2-associated protein 2
chr11_+_86683985	0.187	ENSMUST00000108022.1 ENSMUST00000108021.1	Ptrh2	peptidyl-tRNA hydrolase 2
chr15_+_99670574	0.186	ENSMUST00000023758.7	Asic1	acid-sensing (proton-gated) ion channel 1
chr6_-_48048911	0.180	ENSMUST00000095944.3	Zfp777	zinc finger protein 777
chrM_+_10167	0.175	ENSMUST00000082414.1	mt-Nd4	mitochondrially encoded NADH dehydrogenase 4
chr7_+_127746775	0.164	ENSMUST00000033081.7	Fbxl19	F-box and leucine-rich repeat protein 19
chr6_-_21851914	0.161	ENSMUST00000134635.1 ENSMUST00000123116.1 ENSMUST00000120965.1	Tspan12	tetraspanin 12
chr10_+_116177351	0.146	ENSMUST00000155606.1 ENSMUST00000128399.1	Ptprr	protein tyrosine phosphatase, receptor type, R
chr8_-_4259257	0.142	ENSMUST00000053252.7	Ctxn1	cortexin 1
chr13_-_96542479	0.141	ENSMUST00000022172.4	Polk	polymerase (DNA directed), kappa
chr11_-_86683761	0.136	ENSMUST00000018315.3	Vmp1	vacuole membrane protein 1
chr14_+_31251454	0.134	ENSMUST00000022458.4	Bap1	Brca1 associated protein 1
chr4_+_43641262	0.131	ENSMUST00000123351.1 ENSMUST00000128549.1	Npr2	natriuretic peptide receptor 2
chr8_+_122476196	0.123	ENSMUST00000146634.1 ENSMUST00000134127.1	Ctu2	cytosolic thiouridylase subunit 2 homolog (S. pombe)
chrX_+_42151002	0.112	ENSMUST00000123245.1	Stag2	stromal antigen 2
chr14_+_56887795	0.105	ENSMUST00000022511.8	Zmym2	zinc finger, MYM-type 2
chr9_-_123678782	0.093	ENSMUST00000170591.1 ENSMUST00000171647.1	Slc6a20a	solute carrier family 6 (neurotransmitter transporter), member 20A
chr18_-_36766198	0.092	ENSMUST00000061522.7	Dnd1	dead end homolog 1 (zebrafish)
chr11_-_97187872	0.090	ENSMUST00000001479.4	Kpnb1	karyopherin (importin) beta 1
chr15_+_74516196	0.087	ENSMUST00000042035.9	Bai1	brain-specific angiogenesis inhibitor 1
chr11_+_95414078	0.087	ENSMUST00000107724.2 ENSMUST00000150884.1 ENSMUST00000107722.1 ENSMUST00000127713.1	Spop	speckle-type POZ protein
chr7_+_130577334	0.075	ENSMUST00000059145.7 ENSMUST00000084513.4	Tacc2	transforming, acidic coiled-coil containing protein 2
chr7_+_46796088	0.071	ENSMUST00000006774.4 ENSMUST00000165031.1	Gtf2h1	general transcription factor II H, polypeptide 1
chr6_+_15196949	0.067	ENSMUST00000151301.1 ENSMUST00000131414.1 ENSMUST00000140557.1 ENSMUST00000115469.1	Foxp2	forkhead box P2
chr5_-_137786651	0.051	ENSMUST00000031740.9	Mepce	methylphosphate capping enzyme
chr5_-_137786681	0.048	ENSMUST00000132726.1	Mepce	methylphosphate capping enzyme
chrX_+_140956892	0.040	ENSMUST00000112971.1	Atg4a	autophagy related 4A, cysteine peptidase
chr17_+_48932368	0.037	ENSMUST00000046254.2	Lrfn2	leucine rich repeat and fibronectin type III domain containing 2
chr2_+_25272475	0.035	ENSMUST00000028341.4	Anapc2	anaphase promoting complex subunit 2
chr9_+_120929216	0.033	ENSMUST00000130466.1	Ctnnb1	catenin (cadherin associated protein), beta 1
chr11_+_98741805	0.025	ENSMUST00000064187.5	Thra	thyroid hormone receptor alpha
chr7_-_115824699	0.023	ENSMUST00000169129.1	Sox6	SRY-box containing gene 6
chrX_+_20425688	0.023	ENSMUST00000115384.2	Phf16	PHD finger protein 16
chr13_+_113209659	0.020	ENSMUST00000038144.8	Esm1	endothelial cell-specific molecule 1
chr6_+_83054653	0.013	ENSMUST00000092618.6	Aup1	ancient ubiquitous protein 1
chr8_+_84148252	0.011	ENSMUST00000093375.4	4930432K21Rik	RIKEN cDNA 4930432K21 gene

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	5.7	GO:0035262	gonad morphogenesis(GO:0035262)
0.9	1.9	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.9	3.5	GO:0051866	general adaptation syndrome(GO:0051866)
0.8	2.4	GO:0032474	otolith morphogenesis(GO:0032474)
0.7	2.0	GO:0003104	positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.6	2.5	GO:0060745	mammary gland branching involved in pregnancy(GO:0060745)
0.6	2.4	GO:0030091	protein repair(GO:0030091)
0.6	1.7	GO:0045014	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.5	1.0	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.4	5.2	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.4	0.4	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.4	1.2	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4	3.6	GO:0071493	cellular response to UV-B(GO:0071493)
0.4	1.9	GO:0007386	compartment pattern specification(GO:0007386)
0.3	1.3	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3	0.9	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.3	3.8	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.3	0.8	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3	0.8	GO:0061537	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2	1.2	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.2	1.6	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.2	0.5	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.2	0.5	GO:0006597	spermine biosynthetic process(GO:0006597)
0.2	0.7	GO:0007412	axon target recognition(GO:0007412)
0.2	1.5	GO:0010587	miRNA catabolic process(GO:0010587)
0.2	0.5	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2	1.8	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2	0.5	GO:0015747	urate transport(GO:0015747)
0.1	0.4	GO:2000812	response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812)
0.1	0.9	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	1.1	GO:0090527	actin filament reorganization(GO:0090527)
0.1	0.3	GO:0051715	cytolysis in other organism(GO:0051715)
0.1	0.4	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1	3.6	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	0.3	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.7	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	0.4	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	1.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.3	GO:0002143	tRNA wobble position uridine thiolation(GO:0002143)
0.1	0.7	GO:0071285	cellular response to lithium ion(GO:0071285)
0.1	0.9	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	1.7	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.1	0.3	GO:0014005	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1	0.9	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.1	0.4	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	0.3	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1	0.2	GO:0050915	sensory perception of sour taste(GO:0050915)
0.1	0.4	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.4	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	2.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	0.4	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	0.3	GO:0051189	molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1	0.4	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.6	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.5	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.9	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.7	GO:0007340	acrosome reaction(GO:0007340)
0.0	4.7	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.0	0.4	GO:0046697	decidualization(GO:0046697)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.3	GO:0099628	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0	4.5	GO:0050807	regulation of synapse organization(GO:0050807)
0.0	1.0	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.3	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	1.1	GO:0009060	aerobic respiration(GO:0009060)
0.0	0.2	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	1.0	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.0	GO:0061550	regulation of anagen(GO:0051884) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) cranial ganglion development(GO:0061550)
0.0	0.4	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:1900194	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0	0.5	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.1	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.1	GO:0040031	snRNA modification(GO:0040031)
0.0	0.4	GO:0071385	cellular response to glucocorticoid stimulus(GO:0071385)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.6	GO:0070557	PCNA-p21 complex(GO:0070557)
0.4	2.5	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.3	1.7	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.2	0.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	2.1	GO:0005916	fascia adherens(GO:0005916)
0.2	1.0	GO:0001674	female germ cell nucleus(GO:0001674)
0.1	1.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	0.4	GO:0031983	vesicle lumen(GO:0031983)
0.1	0.3	GO:0099573	glutamatergic postsynaptic density(GO:0099573)
0.1	3.8	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	0.3	GO:0097450	astrocyte end-foot(GO:0097450)
0.1	0.2	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.1	0.6	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	0.9	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	1.6	GO:0001741	XY body(GO:0001741)
0.1	0.2	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	1.8	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	0.4	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	0.4	GO:0071664	beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.1	0.4	GO:0031415	NatA complex(GO:0031415)
0.1	0.8	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	3.5	GO:0005581	collagen trimer(GO:0005581)
0.0	4.9	GO:0032993	protein-DNA complex(GO:0032993)
0.0	1.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	1.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.4	GO:0071564	npBAF complex(GO:0071564)
0.0	0.4	GO:0098839	postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0	1.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.5	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.6	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.9	4.3	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.8	2.5	GO:0031798	type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.5	2.0	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.4	2.4	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.4	1.8	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.3	1.0	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.3	0.9	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3	1.3	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2	3.6	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2	1.7	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2	0.9	GO:0042806	fucose binding(GO:0042806)
0.2	0.9	GO:0050436	microfibril binding(GO:0050436)
0.2	1.2	GO:0070728	leucine binding(GO:0070728)
0.2	1.6	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	1.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	1.5	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	0.5	GO:0019808	polyamine binding(GO:0019808)
0.1	0.5	GO:0004921	interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1	0.5	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	0.3	GO:0031752	D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1	1.6	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	3.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.3	GO:0042834	peptidoglycan binding(GO:0042834)
0.1	0.4	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	0.8	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	0.8	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.1	1.5	GO:0008432	JUN kinase binding(GO:0008432)
0.1	1.9	GO:0005112	Notch binding(GO:0005112)
0.0	1.1	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0	0.4	GO:0036122	BMP binding(GO:0036122)
0.0	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.6	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	3.9	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	1.7	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.9	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	1.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.4	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.4	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.3	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.4	GO:0016595	glutamate binding(GO:0016595)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.3	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.7	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.9	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.0	0.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.6	SA_G2_AND_M_PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	4.5	PID_HNF3A_PATHWAY	FOXA1 transcription factor network
0.0	1.2	PID_FRA_PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.6	PID_SYNDECAN_3_PATHWAY	Syndecan-3-mediated signaling events
0.0	3.5	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.2	PID_FOXO_PATHWAY	FoxO family signaling
0.0	0.9	PID_AMB2_NEUTROPHILS_PATHWAY	amb2 Integrin signaling
0.0	1.2	PID_ERBB4_PATHWAY	ErbB4 signaling events
0.0	0.5	PID_IL23_PATHWAY	IL23-mediated signaling events
0.0	1.9	PID_NOTCH_PATHWAY	Notch signaling pathway
0.0	0.2	SA_REG_CASCADE_OF_CYCLIN_EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.4	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.2	PID_TCR_JNK_PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.4	PID_TOLL_ENDOGENOUS_PATHWAY	Endogenous TLR signaling
0.0	1.2	PID_LKB1_PATHWAY	LKB1 signaling events
0.0	1.0	PID_MYC_REPRESS_PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.5	PID_P38_MKK3_6PATHWAY	p38 MAPK signaling pathway
0.0	1.5	PID_AR_PATHWAY	Coregulation of Androgen receptor activity
0.0	0.7	PID_AP1_PATHWAY	AP-1 transcription factor network
0.0	0.3	PID_PI3K_PLC_TRK_PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	1.2	PID_MYC_ACTIV_PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.4	PID_REELIN_PATHWAY	Reelin signaling pathway
0.0	0.1	PID_SMAD2_3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.2	REACTOME_GAP_JUNCTION_ASSEMBLY	Genes involved in Gap junction assembly
0.1	3.6	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	1.7	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	0.4	REACTOME_ETHANOL_OXIDATION	Genes involved in Ethanol oxidation
0.1	1.8	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	0.5	REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	0.8	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	1.0	REACTOME_HYALURONAN_METABOLISM	Genes involved in Hyaluronan metabolism
0.1	0.8	REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME_IL_6_SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.9	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	1.9	REACTOME_NUCLEAR_SIGNALING_BY_ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.4	REACTOME_CS_DS_DEGRADATION	Genes involved in CS/DS degradation
0.0	1.8	REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.7	REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.7	REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.9	REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	3.7	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.8	REACTOME_SIGNALING_BY_EGFR_IN_CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.4	REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	1.0	REACTOME_MRNA_3_END_PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.4	REACTOME_SIGNALING_BY_BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME_MYOGENESIS	Genes involved in Myogenesis
0.0	0.8	REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.9	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.2	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME_DARPP_32_EVENTS	Genes involved in DARPP-32 events

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