ISMARA results: Tbx2

Motif ID: Tbx2

Z-value: 0.536

Transcription factors associated with Tbx2:

Gene Symbol	Entrez ID	Gene Name
Tbx2	ENSMUSG00000000093.6	Tbx2

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Tbx2	mm10_v2_chr11_+_85832551_85832551	0.16	5.1e-01	Click!

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Showing 1 to 20 of 113 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_53850243	0.725	ENSMUST00000048485.5	Sln	sarcolipin
chr5_+_111733924	0.607	ENSMUST00000180627.1	Gm26897	predicted gene, 26897
chr12_+_85473883	0.598	ENSMUST00000021674.6	Fos	FBJ osteosarcoma oncogene
chr4_+_84884418	0.529	ENSMUST00000169371.2	Cntln	centlein, centrosomal protein
chr4_+_94614483	0.494	ENSMUST00000030311.4 ENSMUST00000107104.2	Ift74	intraflagellar transport 74
chr18_-_62741387	0.439	ENSMUST00000097557.3	Spink13	serine peptidase inhibitor, Kazal type 13
chr5_+_32136458	0.430	ENSMUST00000031017.9	Fosl2	fos-like antigen 2
chr11_-_84068766	0.411	ENSMUST00000018792.5	Dusp14	dual specificity phosphatase 14
chr3_-_145649970	0.409	ENSMUST00000029846.3	Cyr61	cysteine rich protein 61
chr4_+_84884276	0.379	ENSMUST00000047023.6	Cntln	centlein, centrosomal protein
chr14_+_80000292	0.377	ENSMUST00000088735.3	Olfm4	olfactomedin 4
chr10_+_106470281	0.368	ENSMUST00000029404.9 ENSMUST00000169303.1	Ppfia2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr11_+_103101682	0.343	ENSMUST00000107040.3 ENSMUST00000140372.1 ENSMUST00000024492.8 ENSMUST00000134884.1	Acbd4	acyl-Coenzyme A binding domain containing 4
chr16_+_23107413	0.320	ENSMUST00000023599.6 ENSMUST00000168891.1	Eif4a2	eukaryotic translation initiation factor 4A2
chr11_-_84068357	0.308	ENSMUST00000100705.4	Dusp14	dual specificity phosphatase 14
chr12_-_31634592	0.307	ENSMUST00000020979.7 ENSMUST00000177962.1	Bcap29	B cell receptor associated protein 29
chrX_+_159840463	0.300	ENSMUST00000112451.1 ENSMUST00000112453.2	Sh3kbp1	SH3-domain kinase binding protein 1
chr4_+_84884366	0.300	ENSMUST00000102819.3	Cntln	centlein, centrosomal protein
chr2_+_175469985	0.292	ENSMUST00000109042.3 ENSMUST00000109002.2 ENSMUST00000109043.2 ENSMUST00000143490.1	Gm8923	predicted gene 8923
chr19_-_28963863	0.275	ENSMUST00000161813.1	4430402I18Rik	RIKEN cDNA 4430402I18 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 32 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.2	0.7	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894)
0.0	0.7	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.6	GO:0035994	response to muscle stretch(GO:0035994)
0.1	0.5	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.5	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1	0.4	GO:0060467	negative regulation of fertilization(GO:0060467)
0.1	0.4	GO:0060591	chondroblast differentiation(GO:0060591)
0.0	0.4	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.4	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.4	GO:0090161	Golgi ribbon formation(GO:0090161)
0.1	0.3	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.3	GO:1904565	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0	0.3	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	0.2	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.2	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.2	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	0.2	GO:0008078	mesodermal cell migration(GO:0008078)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.2	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)

Gene overrepresentation in cellular_component category:

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Showing 1 to 12 of 12 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	0.6	GO:0035976	AP1 complex(GO:0035976)
0.0	0.5	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.4	GO:0042581	specific granule(GO:0042581)
0.0	0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.4	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	0.2	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.1	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0	0.1	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.0	0.1	GO:0098842	postsynaptic early endosome(GO:0098842)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)

Gene overrepresentation in molecular_function category:

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Showing 1 to 17 of 17 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.6	GO:0070412	R-SMAD binding(GO:0070412)
0.1	0.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.3	GO:0035727	lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.0	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.0	GO:0042610	CD8 receptor binding(GO:0042610)

Gene overrepresentation in C2:CP category:

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Showing 1 to 4 of 4 entries

Total log-likelihood	Term	Description
0.6	PID_TCR_RAS_PATHWAY	Ras signaling in the CD4+ TCR pathway
0.5	PID_TRAIL_PATHWAY	TRAIL signaling pathway
0.4	PID_INTEGRIN2_PATHWAY	Beta2 integrin cell surface interactions
0.4	PID_FRA_PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 6 of 6 entries

Total log-likelihood	Term	Description
0.6	REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.4	REACTOME_IL_7_SIGNALING	Genes involved in Interleukin-7 signaling
0.4	REACTOME_DEADENYLATION_OF_MRNA	Genes involved in Deadenylation of mRNA
0.3	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	REACTOME_REGULATION_OF_SIGNALING_BY_CBL	Genes involved in Regulation of signaling by CBL