Motif ID: Tbx20

Z-value: 0.293


Transcription factors associated with Tbx20:

Gene SymbolEntrez IDGene Name
Tbx20 ENSMUSG00000031965.8 Tbx20



Activity profile for motif Tbx20.

activity profile for motif Tbx20


Sorted Z-values histogram for motif Tbx20

Sorted Z-values for motif Tbx20



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx20

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_79660196 0.566 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr6_+_15196949 0.469 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr8_-_22694061 0.416 ENSMUST00000131767.1
Ikbkb
inhibitor of kappaB kinase beta
chr7_-_105787544 0.347 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr12_+_51348265 0.306 ENSMUST00000119211.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr12_+_51348370 0.281 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr6_-_122340499 0.271 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr7_-_105787567 0.246 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr5_-_53707532 0.226 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr9_-_73039644 0.225 ENSMUST00000184389.1
Pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr9_+_112227443 0.151 ENSMUST00000161216.1
2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr19_+_38055002 0.132 ENSMUST00000096096.4
ENSMUST00000116506.1
ENSMUST00000169673.1
Cep55


centrosomal protein 55


chr9_-_73039697 0.124 ENSMUST00000184035.1
ENSMUST00000098566.4
Pigb

phosphatidylinositol glycan anchor biosynthesis, class B

chr4_-_118437331 0.118 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr8_+_83900706 0.104 ENSMUST00000045393.8
ENSMUST00000132500.1
ENSMUST00000152978.1
Lphn1


latrophilin 1


chr8_-_3694167 0.101 ENSMUST00000005678.4
Fcer2a
Fc receptor, IgE, low affinity II, alpha polypeptide
chr5_-_120777628 0.091 ENSMUST00000044833.8
Oas3
2'-5' oligoadenylate synthetase 3
chrX_+_99042581 0.086 ENSMUST00000036606.7
Stard8
START domain containing 8
chr2_+_54436317 0.080 ENSMUST00000112636.1
ENSMUST00000112635.1
ENSMUST00000112634.1
Galnt13


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13


chr6_-_122340525 0.044 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr15_-_102516806 0.026 ENSMUST00000169162.1
ENSMUST00000023812.2
ENSMUST00000165174.1
ENSMUST00000169367.1
ENSMUST00000169377.1
Map3k12




mitogen-activated protein kinase kinase kinase 12




chr11_-_86807624 0.015 ENSMUST00000018569.7
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr2_+_34406845 0.012 ENSMUST00000124443.1
ENSMUST00000113124.1
Mapkap1

mitogen-activated protein kinase associated protein 1

chr2_+_34406949 0.011 ENSMUST00000040459.4
Mapkap1
mitogen-activated protein kinase associated protein 1
chr17_-_23745829 0.009 ENSMUST00000046525.8
Kremen2
kringle containing transmembrane protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.2 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 0.6 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.5 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.3 GO:0097502 mannosylation(GO:0097502)
0.0 0.1 GO:0000279 M phase(GO:0000279)
0.0 0.1 GO:0060700 regulation of ribonuclease activity(GO:0060700)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)