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Motif ID: Tbx3

Z-value: 0.394

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_-_4522427	0.890	ENSMUST00000098859.3	Tnni3	troponin I, cardiac 3
chr7_-_4522794	0.687	ENSMUST00000140424.1	Tnni3	troponin I, cardiac 3
chr10_+_127514939	0.638	ENSMUST00000035735.9	Ndufa4l2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr11_-_94507337	0.606	ENSMUST00000040692.8	Mycbpap	MYCBP associated protein
chr14_+_67745229	0.542	ENSMUST00000111095.2	Gnrh1	gonadotropin releasing hormone 1
chr2_+_154551771	0.434	ENSMUST00000104928.1	Actl10	actin-like 10
chrX_-_20931520	0.429	ENSMUST00000001156.7	Cfp	complement factor properdin
chr17_-_59013264	0.427	ENSMUST00000174122.1 ENSMUST00000025065.5	Nudt12	nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr18_-_23981555	0.353	ENSMUST00000115829.1	Zscan30	zinc finger and SCAN domain containing 30
chr10_+_56377300	0.297	ENSMUST00000068581.7	Gja1	gap junction protein, alpha 1
chr5_-_106926245	0.257	ENSMUST00000117588.1	Hfm1	HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr19_+_7056731	0.220	ENSMUST00000040261.5	Macrod1	MACRO domain containing 1
chr1_-_31222604	0.203	ENSMUST00000127775.1	4931428L18Rik	RIKEN cDNA 4931428L18 gene
chr12_+_84361636	0.095	ENSMUST00000110276.1	Coq6	coenzyme Q6 homolog (yeast)
chr3_+_89246397	0.094	ENSMUST00000168900.1	Krtcap2	keratinocyte associated protein 2
chr1_+_93215899	0.085	ENSMUST00000138595.1	E030010N08Rik	RIKEN cDNA E030010N08 gene
chr12_-_84361802	0.068	ENSMUST00000021659.1 ENSMUST00000065536.2	Fam161b	family with sequence similarity 161, member B
chr7_+_107567445	0.061	ENSMUST00000120990.1	Olfml1	olfactomedin-like 1
chr12_+_84361968	0.048	ENSMUST00000021661.6	Coq6	coenzyme Q6 homolog (yeast)
chr11_-_100970887	0.029	ENSMUST00000060792.5	Ptrf	polymerase I and transcript release factor
chr13_+_108046411	0.027	ENSMUST00000095458.4	Smim15	small integral membrane protein 15
chr12_+_84362029	0.016	ENSMUST00000110278.1 ENSMUST00000145522.1	Coq6	coenzyme Q6 homolog (yeast)
chr4_+_135759705	0.004	ENSMUST00000105854.1	Myom3	myomesin family, member 3

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.6	GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.1	0.5	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087)
0.1	0.4	GO:0006742	NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1	0.3	GO:0003104	positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.1	0.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.2	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.3	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.6	GO:1990584	cardiac Troponin complex(GO:1990584)
0.1	0.5	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.6	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:0030172	troponin C binding(GO:0030172)
0.1	0.4	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	0.3	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0	0.6	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	PID_AR_NONGENOMIC_PATHWAY	Nongenotropic Androgen signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.1	1.6	REACTOME_STRIATED_MUSCLE_CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.3	REACTOME_GAP_JUNCTION_ASSEMBLY	Genes involved in Gap junction assembly

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