Motif ID: Tcf21_Msc
Z-value: 1.156
Transcription factors associated with Tcf21_Msc:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Msc | ENSMUSG00000025930.5 | Msc |
Tcf21 | ENSMUSG00000045680.7 | Tcf21 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.5 | GO:0006601 | creatine biosynthetic process(GO:0006601) |
0.3 | 0.9 | GO:0018094 | protein polyglycylation(GO:0018094) |
0.3 | 1.2 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.3 | 0.8 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
0.2 | 1.2 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) positive regulation of NAD(P)H oxidase activity(GO:0033864) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137) |
0.2 | 1.4 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
0.2 | 0.7 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
0.2 | 2.2 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.2 | 0.8 | GO:1904451 | regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
0.2 | 0.6 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.2 | 0.6 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.2 | 0.2 | GO:0010957 | negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) |
0.2 | 0.5 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
0.2 | 0.7 | GO:0072272 | proximal/distal pattern formation involved in metanephric nephron development(GO:0072272) |
0.2 | 0.8 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.2 | 0.8 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
0.2 | 0.6 | GO:0071105 | response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105) |
0.1 | 0.4 | GO:0098968 | neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968) |
0.1 | 0.7 | GO:0061511 | centriole elongation(GO:0061511) |
0.1 | 1.4 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.1 | 1.1 | GO:0030035 | microspike assembly(GO:0030035) |
0.1 | 0.3 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
0.1 | 0.4 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
0.1 | 2.0 | GO:0048240 | sperm capacitation(GO:0048240) |
0.1 | 0.3 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
0.1 | 1.0 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.1 | 0.3 | GO:2000484 | regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) positive regulation of interleukin-8 secretion(GO:2000484) |
0.1 | 0.3 | GO:0036292 | DNA rewinding(GO:0036292) |
0.1 | 0.7 | GO:0042574 | retinal metabolic process(GO:0042574) |
0.1 | 0.6 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.1 | 0.3 | GO:0035622 | intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034) |
0.1 | 0.7 | GO:0043383 | negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060) |
0.1 | 0.8 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
0.1 | 0.5 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
0.1 | 0.4 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
0.1 | 1.0 | GO:0090205 | positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205) |
0.1 | 1.4 | GO:0006721 | terpenoid metabolic process(GO:0006721) |
0.1 | 0.5 | GO:0021593 | rhombomere morphogenesis(GO:0021593) |
0.1 | 0.2 | GO:0021852 | pyramidal neuron migration(GO:0021852) |
0.1 | 0.7 | GO:2000194 | regulation of female gonad development(GO:2000194) |
0.1 | 0.4 | GO:0050912 | detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
0.1 | 0.5 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.1 | 0.9 | GO:0032695 | negative regulation of interleukin-12 production(GO:0032695) |
0.1 | 2.5 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
0.1 | 0.4 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
0.1 | 0.3 | GO:0032224 | positive regulation of synaptic transmission, cholinergic(GO:0032224) |
0.1 | 0.4 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
0.1 | 0.2 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
0.1 | 0.6 | GO:0006013 | mannose metabolic process(GO:0006013) |
0.1 | 0.6 | GO:0042095 | interferon-gamma biosynthetic process(GO:0042095) |
0.1 | 0.2 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
0.1 | 0.2 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) |
0.1 | 0.6 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.1 | 0.2 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.1 | 0.2 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.1 | 0.2 | GO:0016332 | establishment or maintenance of polarity of embryonic epithelium(GO:0016332) |
0.1 | 0.4 | GO:0042473 | outer ear morphogenesis(GO:0042473) |
0.1 | 0.9 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
0.1 | 0.2 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.1 | 0.6 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.1 | 0.1 | GO:1902730 | positive regulation of proteoglycan biosynthetic process(GO:1902730) |
0.1 | 0.3 | GO:0003062 | regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065) |
0.1 | 0.2 | GO:2000318 | positive regulation of T-helper 17 type immune response(GO:2000318) |
0.1 | 0.2 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
0.1 | 0.2 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
0.0 | 0.2 | GO:0033580 | protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125) |
0.0 | 0.3 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
0.0 | 0.4 | GO:0048625 | myoblast fate commitment(GO:0048625) |
0.0 | 0.2 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
0.0 | 0.2 | GO:0042891 | antibiotic transport(GO:0042891) |
0.0 | 0.3 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
0.0 | 0.2 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
0.0 | 0.9 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.0 | 0.3 | GO:0061365 | positive regulation of triglyceride lipase activity(GO:0061365) |
0.0 | 0.2 | GO:0061009 | common bile duct development(GO:0061009) |
0.0 | 0.1 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
0.0 | 0.2 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
0.0 | 0.4 | GO:0014842 | regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857) |
0.0 | 0.2 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.0 | 0.3 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.0 | 0.2 | GO:1904781 | positive regulation of protein localization to centrosome(GO:1904781) |
0.0 | 0.7 | GO:0048368 | lateral mesoderm development(GO:0048368) |
0.0 | 0.2 | GO:0032298 | positive regulation of DNA-dependent DNA replication initiation(GO:0032298) |
0.0 | 0.2 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
0.0 | 0.4 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.0 | 0.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.0 | 0.2 | GO:0072429 | response to intra-S DNA damage checkpoint signaling(GO:0072429) |
0.0 | 0.3 | GO:0044336 | canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) |
0.0 | 0.9 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.0 | 0.2 | GO:0060372 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) |
0.0 | 0.7 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.1 | GO:0006553 | lysine metabolic process(GO:0006553) |
0.0 | 0.4 | GO:0051043 | regulation of membrane protein ectodomain proteolysis(GO:0051043) |
0.0 | 0.1 | GO:0035799 | ureter maturation(GO:0035799) |
0.0 | 1.0 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.0 | 0.3 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
0.0 | 0.8 | GO:0031643 | positive regulation of myelination(GO:0031643) |
0.0 | 0.9 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
0.0 | 0.3 | GO:0030432 | peristalsis(GO:0030432) |
0.0 | 0.1 | GO:0042117 | monocyte activation(GO:0042117) |
0.0 | 0.2 | GO:0032264 | IMP salvage(GO:0032264) |
0.0 | 0.1 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
0.0 | 0.1 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
0.0 | 0.1 | GO:1990523 | bone regeneration(GO:1990523) |
0.0 | 0.3 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
0.0 | 0.3 | GO:0007602 | phototransduction(GO:0007602) |
0.0 | 0.1 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
0.0 | 0.1 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
0.0 | 0.2 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
0.0 | 0.1 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
0.0 | 0.2 | GO:0010713 | negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) |
0.0 | 0.2 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
0.0 | 0.4 | GO:0097084 | vascular smooth muscle cell development(GO:0097084) |
0.0 | 0.3 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.0 | 0.3 | GO:0033004 | negative regulation of mast cell activation(GO:0033004) |
0.0 | 0.1 | GO:0010891 | negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898) |
0.0 | 0.2 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
0.0 | 0.4 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
0.0 | 0.2 | GO:0015074 | DNA integration(GO:0015074) |
0.0 | 0.3 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
0.0 | 0.3 | GO:0090003 | regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003) |
0.0 | 0.3 | GO:0060297 | regulation of sarcomere organization(GO:0060297) |
0.0 | 0.8 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 0.1 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
0.0 | 0.7 | GO:0097320 | membrane tubulation(GO:0097320) |
0.0 | 0.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 0.3 | GO:0060033 | anatomical structure regression(GO:0060033) |
0.0 | 0.8 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.1 | GO:0045759 | negative regulation of action potential(GO:0045759) |
0.0 | 0.6 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
0.0 | 0.1 | GO:0046381 | CMP-N-acetylneuraminate metabolic process(GO:0046381) |
0.0 | 0.1 | GO:0048254 | snoRNA localization(GO:0048254) |
0.0 | 0.3 | GO:0007093 | mitotic cell cycle checkpoint(GO:0007093) |
0.0 | 0.3 | GO:0032060 | bleb assembly(GO:0032060) |
0.0 | 0.4 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
0.0 | 0.2 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
0.0 | 2.3 | GO:0051592 | response to calcium ion(GO:0051592) |
0.0 | 0.3 | GO:0050965 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
0.0 | 0.6 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 0.3 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.8 | GO:1901264 | carbohydrate derivative transport(GO:1901264) |
0.0 | 0.4 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
0.0 | 0.3 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
0.0 | 0.1 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
0.0 | 1.0 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 0.1 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.0 | 0.1 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
0.0 | 0.4 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
0.0 | 0.1 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
0.0 | 0.1 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
0.0 | 0.3 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
0.0 | 0.1 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
0.0 | 0.1 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
0.0 | 0.8 | GO:0050830 | defense response to Gram-positive bacterium(GO:0050830) |
0.0 | 0.1 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.0 | 0.1 | GO:1900112 | regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.0 | 0.0 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
0.0 | 0.1 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
0.0 | 0.5 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
0.0 | 0.3 | GO:0045475 | locomotor rhythm(GO:0045475) |
0.0 | 0.4 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.0 | 0.2 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 1.1 | GO:0048709 | oligodendrocyte differentiation(GO:0048709) |
0.0 | 0.1 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.0 | 0.6 | GO:0016925 | protein sumoylation(GO:0016925) |
0.0 | 0.1 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.0 | 0.3 | GO:0060008 | Sertoli cell differentiation(GO:0060008) |
0.0 | 0.1 | GO:0045780 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
0.0 | 0.0 | GO:1905169 | protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171) |
0.0 | 0.1 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
0.0 | 0.2 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
0.0 | 0.0 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
0.0 | 0.2 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.0 | 0.0 | GO:1901072 | glucosamine-containing compound catabolic process(GO:1901072) |
0.0 | 0.1 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
0.0 | 0.1 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
0.0 | 0.2 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.0 | 0.1 | GO:0045793 | positive regulation of cell size(GO:0045793) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
0.2 | 1.2 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.2 | 0.8 | GO:0097574 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) |
0.2 | 0.8 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 0.3 | GO:0071438 | integrin alpha3-beta1 complex(GO:0034667) invadopodium membrane(GO:0071438) |
0.1 | 0.4 | GO:0001651 | dense fibrillar component(GO:0001651) |
0.1 | 0.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.1 | 0.4 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.1 | 0.3 | GO:1990423 | RZZ complex(GO:1990423) |
0.1 | 0.3 | GO:0061702 | inflammasome complex(GO:0061702) |
0.1 | 1.0 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.1 | 0.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.1 | 0.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.1 | 0.4 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.1 | 0.2 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
0.0 | 1.3 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.3 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.0 | 0.4 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.0 | 1.0 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 0.6 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.6 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.0 | 0.2 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
0.0 | 0.3 | GO:0042629 | mast cell granule(GO:0042629) |
0.0 | 0.2 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
0.0 | 0.5 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.0 | 0.1 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
0.0 | 0.3 | GO:0061574 | ASAP complex(GO:0061574) |
0.0 | 0.3 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.3 | GO:0030478 | actin cap(GO:0030478) |
0.0 | 0.5 | GO:0035102 | PRC1 complex(GO:0035102) |
0.0 | 0.1 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 2.2 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.1 | GO:0098536 | deuterosome(GO:0098536) |
0.0 | 0.3 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.0 | 0.3 | GO:0043596 | nuclear replication fork(GO:0043596) |
0.0 | 0.7 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.4 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 0.1 | GO:0005940 | septin ring(GO:0005940) |
0.0 | 0.1 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.0 | 2.2 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.1 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
0.0 | 0.1 | GO:0033269 | internode region of axon(GO:0033269) |
0.0 | 0.3 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 0.3 | GO:0043218 | compact myelin(GO:0043218) |
0.0 | 0.1 | GO:1990357 | terminal web(GO:1990357) |
0.0 | 0.1 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
0.0 | 0.2 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.0 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 0.5 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 1.0 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 0.2 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.4 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.7 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 0.4 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.1 | GO:0070552 | BRISC complex(GO:0070552) |
0.0 | 0.4 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.0 | 0.9 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.1 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.0 | 0.1 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.0 | 1.7 | GO:0032993 | protein-DNA complex(GO:0032993) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 2.2 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.3 | 0.9 | GO:0070736 | protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) |
0.3 | 1.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.2 | 0.7 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
0.2 | 0.7 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.2 | 1.0 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.2 | 0.6 | GO:0004568 | chitinase activity(GO:0004568) |
0.2 | 0.5 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
0.2 | 0.8 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.2 | 0.5 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
0.2 | 0.9 | GO:0019841 | retinal binding(GO:0016918) retinol binding(GO:0019841) |
0.1 | 1.5 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
0.1 | 0.6 | GO:0004103 | choline kinase activity(GO:0004103) |
0.1 | 0.8 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
0.1 | 0.4 | GO:0008527 | taste receptor activity(GO:0008527) |
0.1 | 0.9 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.1 | 0.4 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.1 | 0.7 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
0.1 | 1.2 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.1 | 0.5 | GO:0070492 | oligosaccharide binding(GO:0070492) |
0.1 | 0.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.1 | 0.6 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.1 | 1.4 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.1 | 0.2 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
0.1 | 1.6 | GO:0016769 | transferase activity, transferring nitrogenous groups(GO:0016769) |
0.1 | 0.3 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
0.1 | 0.4 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.1 | 0.4 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
0.1 | 0.4 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
0.1 | 0.5 | GO:0034046 | poly(G) binding(GO:0034046) |
0.1 | 0.6 | GO:0050693 | LBD domain binding(GO:0050693) |
0.1 | 0.7 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.1 | 0.2 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.0 | 0.6 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.0 | 0.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.0 | 1.0 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.2 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
0.0 | 0.3 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 0.4 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.0 | 0.1 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
0.0 | 0.5 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.3 | GO:0031432 | titin binding(GO:0031432) |
0.0 | 0.7 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
0.0 | 0.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 1.6 | GO:0016504 | peptidase activator activity(GO:0016504) |
0.0 | 0.2 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
0.0 | 0.4 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.2 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.0 | 0.2 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
0.0 | 0.2 | GO:0009374 | biotin binding(GO:0009374) |
0.0 | 0.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.0 | 0.5 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
0.0 | 0.1 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.0 | 0.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.0 | 0.5 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.4 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.1 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.0 | 0.2 | GO:0048256 | flap endonuclease activity(GO:0048256) |
0.0 | 0.3 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.0 | 0.3 | GO:0036310 | annealing helicase activity(GO:0036310) |
0.0 | 0.1 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.0 | 0.1 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
0.0 | 0.1 | GO:0004645 | phosphorylase activity(GO:0004645) |
0.0 | 0.6 | GO:0043236 | laminin binding(GO:0043236) |
0.0 | 0.6 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 0.1 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
0.0 | 0.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.9 | GO:1901505 | carbohydrate derivative transporter activity(GO:1901505) |
0.0 | 0.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.0 | 0.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 3.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.1 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.0 | 0.4 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.2 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
0.0 | 0.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.7 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 0.1 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.0 | 0.4 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.0 | 0.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.1 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.0 | 0.1 | GO:0016708 | nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726) |
0.0 | 0.1 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
0.0 | 0.3 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
0.0 | 0.1 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.0 | 0.4 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.0 | 0.7 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 0.3 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 0.0 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
0.0 | 0.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.2 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 0.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.2 | GO:0005003 | ephrin receptor activity(GO:0005003) |
0.0 | 1.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.3 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
0.0 | 0.7 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
0.0 | 0.4 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.2 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.0 | 0.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.0 | 0.4 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.5 | GO:0004521 | endoribonuclease activity(GO:0004521) |
0.0 | 0.3 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.8 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.0 | 0.8 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 0.3 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 0.3 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
0.0 | 0.7 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
0.0 | 1.0 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.9 | PID_MYC_PATHWAY | C-MYC pathway |
0.0 | 0.6 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.8 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.7 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.0 | 0.3 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.0 | 1.6 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.0 | 0.2 | PID_NEPHRIN_NEPH1_PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
0.0 | 0.2 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.0 | 0.6 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.5 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 1.0 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.2 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.0 | 0.1 | PID_IL27_PATHWAY | IL27-mediated signaling events |
0.0 | 1.7 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.5 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 0.5 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 1.7 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.4 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 0.1 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.0 | 0.5 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 0.2 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.6 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.1 | 1.0 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
0.1 | 0.7 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.1 | 0.3 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.1 | 0.3 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.0 | 1.0 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
0.0 | 1.2 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.0 | 1.2 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.0 | 2.0 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.0 | 1.0 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.0 | 0.4 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 0.4 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.0 | 0.2 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
0.0 | 1.8 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.2 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.0 | 0.4 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.0 | 0.6 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.3 | REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
0.0 | 1.2 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.1 | REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE | Genes involved in p53-Dependent G1 DNA Damage Response |
0.0 | 0.6 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.6 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.2 | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Activation of the pre-replicative complex |
0.0 | 0.2 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.3 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.1 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |