Motif ID: Tfcp2

Z-value: 2.113


Transcription factors associated with Tfcp2:

Gene SymbolEntrez IDGene Name
Tfcp2 ENSMUSG00000009733.8 Tfcp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfcp2mm10_v2_chr15_-_100551959_100552010-0.233.7e-01Click!


Activity profile for motif Tfcp2.

activity profile for motif Tfcp2


Sorted Z-values histogram for motif Tfcp2

Sorted Z-values for motif Tfcp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfcp2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_87156127 8.613 ENSMUST00000160810.1
Ecel1
endothelin converting enzyme-like 1
chr6_+_5390387 8.204 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr11_-_89302545 6.061 ENSMUST00000061728.3
Nog
noggin
chr16_-_26989974 6.048 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr8_+_57511833 5.995 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr1_+_107511489 5.875 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr1_+_107511416 5.662 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr11_-_22001605 5.313 ENSMUST00000006071.7
Otx1
orthodenticle homolog 1 (Drosophila)
chr8_+_69822429 5.236 ENSMUST00000164890.1
ENSMUST00000034325.4
Lpar2

lysophosphatidic acid receptor 2

chr2_-_166155272 4.911 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr14_-_21989475 4.533 ENSMUST00000043409.7
Zfp503
zinc finger protein 503
chr12_+_24708984 4.448 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr6_+_56017489 4.435 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr10_-_42583628 4.372 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr2_-_102186322 4.295 ENSMUST00000111222.1
ENSMUST00000058790.5
Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr5_+_92809372 4.245 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr2_-_166155624 4.172 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr1_-_131097535 4.020 ENSMUST00000016672.4
Mapkapk2
MAP kinase-activated protein kinase 2
chr18_+_60925644 4.013 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chrX_+_56779437 4.011 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr11_+_69045640 3.990 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr18_+_60925612 3.759 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr9_-_96862903 3.596 ENSMUST00000121077.1
ENSMUST00000124923.1
Acpl2

acid phosphatase-like 2

chr18_+_11633276 3.528 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr12_-_91779129 3.488 ENSMUST00000170077.1
Ston2
stonin 2
chrX_+_73639414 3.482 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr2_-_5012716 3.365 ENSMUST00000027980.7
Mcm10
minichromosome maintenance deficient 10 (S. cerevisiae)
chr4_-_153482768 3.259 ENSMUST00000105646.2
Ajap1
adherens junction associated protein 1
chr16_-_96127604 3.233 ENSMUST00000133885.1
ENSMUST00000050884.7
Hmgn1

high mobility group nucleosomal binding domain 1

chr13_-_100786402 3.230 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
Ccnb1


cyclin B1


chr1_+_184034381 3.177 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr1_+_61638819 3.165 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr4_-_21685782 3.074 ENSMUST00000076206.4
Prdm13
PR domain containing 13
chr17_+_34593388 2.764 ENSMUST00000174532.1
Pbx2
pre B cell leukemia homeobox 2
chr6_+_127887582 2.725 ENSMUST00000032501.4
Tspan11
tetraspanin 11
chr11_+_28853189 2.702 ENSMUST00000020759.5
Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr6_-_39557830 2.702 ENSMUST00000036877.3
ENSMUST00000154149.1
Dennd2a

DENN/MADD domain containing 2A

chr7_+_136894598 2.644 ENSMUST00000081510.2
Mgmt
O-6-methylguanine-DNA methyltransferase
chr14_-_34374617 2.640 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr1_-_184033998 2.619 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr16_+_20673517 2.590 ENSMUST00000115460.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chrX_+_36795642 2.503 ENSMUST00000016463.3
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr12_+_17266545 2.481 ENSMUST00000057288.5
Pdia6
protein disulfide isomerase associated 6
chr11_-_84067063 2.447 ENSMUST00000108101.1
Dusp14
dual specificity phosphatase 14
chr1_+_44551483 2.447 ENSMUST00000074525.3
Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr3_+_134828993 2.365 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr5_-_24577467 2.355 ENSMUST00000030795.8
Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr4_+_89137122 2.314 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr4_-_133967953 2.265 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr4_-_132422394 2.250 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr4_-_133967893 2.227 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr12_+_78861693 2.179 ENSMUST00000071230.7
Eif2s1
eukaryotic translation initiation factor 2, subunit 1 alpha
chr11_-_82829024 2.175 ENSMUST00000021036.6
ENSMUST00000074515.4
ENSMUST00000103218.2
Rffl


ring finger and FYVE like domain containing protein


chr11_+_98937669 2.172 ENSMUST00000107475.2
ENSMUST00000068133.3
Rara

retinoic acid receptor, alpha

chr2_+_16356744 2.164 ENSMUST00000114703.3
Plxdc2
plexin domain containing 2
chr10_+_69212634 2.137 ENSMUST00000020101.5
Rhobtb1
Rho-related BTB domain containing 1
chr16_+_38902305 2.136 ENSMUST00000023478.7
Igsf11
immunoglobulin superfamily, member 11
chr4_+_115088708 2.087 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
Pdzk1ip1



PDZK1 interacting protein 1



chr15_-_85578070 2.087 ENSMUST00000109424.2
Wnt7b
wingless-related MMTV integration site 7B
chrX_-_102250940 2.083 ENSMUST00000134887.1
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr10_+_69212676 2.068 ENSMUST00000167384.1
Rhobtb1
Rho-related BTB domain containing 1
chr1_-_161251153 2.035 ENSMUST00000051925.4
ENSMUST00000071718.5
Prdx6

peroxiredoxin 6

chr2_+_163225363 2.030 ENSMUST00000099110.3
ENSMUST00000165937.1
Tox2

TOX high mobility group box family member 2

chr16_-_20610741 2.029 ENSMUST00000045918.8
Alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr5_-_100500592 1.965 ENSMUST00000149714.1
ENSMUST00000046154.5
Lin54

lin-54 homolog (C. elegans)

chr2_+_112261926 1.945 ENSMUST00000028553.3
Nop10
NOP10 ribonucleoprotein
chr8_+_94172618 1.935 ENSMUST00000034214.6
Mt2
metallothionein 2
chr5_+_33658567 1.918 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chrX_-_164076100 1.901 ENSMUST00000037928.2
ENSMUST00000071667.2
Siah1b

seven in absentia 1B

chr7_-_90129339 1.888 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr15_-_100424092 1.850 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr4_-_154025867 1.846 ENSMUST00000130175.1
ENSMUST00000182151.1
Smim1

small integral membrane protein 1

chr4_-_154025926 1.818 ENSMUST00000132541.1
ENSMUST00000143047.1
Smim1

small integral membrane protein 1

chr4_+_109676568 1.774 ENSMUST00000102724.4
Faf1
Fas-associated factor 1
chrX_-_37085402 1.768 ENSMUST00000115231.3
Rpl39
ribosomal protein L39
chr5_+_33658550 1.764 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr9_+_65214690 1.751 ENSMUST00000069000.7
Parp16
poly (ADP-ribose) polymerase family, member 16
chr16_+_20673264 1.682 ENSMUST00000154950.1
ENSMUST00000115461.1
Eif4g1

eukaryotic translation initiation factor 4, gamma 1

chr11_+_3289880 1.673 ENSMUST00000110043.1
ENSMUST00000094471.3
Patz1

POZ (BTB) and AT hook containing zinc finger 1

chrX_+_74254679 1.633 ENSMUST00000002029.6
Emd
emerin
chr9_+_35423582 1.632 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr3_+_95622236 1.626 ENSMUST00000074353.4
Rps10-ps1
ribosomal protein S10, pseudogene 1
chrX_+_74254736 1.613 ENSMUST00000096424.4
Emd
emerin
chr12_-_65073927 1.600 ENSMUST00000021332.8
Fkbp3
FK506 binding protein 3
chr17_-_25727364 1.591 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr5_+_138363719 1.591 ENSMUST00000100526.2
Gm10874
predicted gene 10874
chr5_-_142905816 1.584 ENSMUST00000171419.1
Actb
actin, beta
chr5_-_30073554 1.571 ENSMUST00000026846.6
Tyms
thymidylate synthase
chr4_-_154025616 1.509 ENSMUST00000182191.1
ENSMUST00000146543.2
Smim1

small integral membrane protein 1

chr11_-_100939540 1.496 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr5_-_142905928 1.493 ENSMUST00000106216.2
Actb
actin, beta
chr6_+_134929118 1.481 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr14_-_26066961 1.481 ENSMUST00000100818.5
Tmem254c
transmembrane protein 254c
chr8_+_33599608 1.479 ENSMUST00000009774.9
Ppp2cb
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
chr4_+_133584419 1.452 ENSMUST00000105899.1
Gpn2
GPN-loop GTPase 2
chrX_+_74254782 1.440 ENSMUST00000119197.1
ENSMUST00000088313.4
Emd

emerin

chr2_+_70508813 1.431 ENSMUST00000100041.2
Erich2
glutamate rich 2
chr13_-_24937585 1.430 ENSMUST00000037615.6
Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr15_-_74734313 1.428 ENSMUST00000023260.3
Lypd2
Ly6/Plaur domain containing 2
chr14_-_26206619 1.414 ENSMUST00000100806.5
Tmem254b
transmembrane protein 254b
chr7_+_141447645 1.403 ENSMUST00000106004.1
ENSMUST00000106003.1
Rplp2

ribosomal protein, large P2

chr2_+_83724397 1.403 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
Itgav


integrin alpha V


chr15_-_93336800 1.386 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr11_-_100939357 1.356 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr4_+_133584355 1.337 ENSMUST00000030661.7
Gpn2
GPN-loop GTPase 2
chr16_+_20672716 1.314 ENSMUST00000044783.7
ENSMUST00000115463.1
ENSMUST00000142344.1
ENSMUST00000073840.5
ENSMUST00000140576.1
ENSMUST00000115457.1
Eif4g1





eukaryotic translation initiation factor 4, gamma 1





chr6_+_134929089 1.305 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr1_+_16665189 1.301 ENSMUST00000177501.1
ENSMUST00000065373.5
Tmem70

transmembrane protein 70

chr3_-_141931523 1.299 ENSMUST00000106232.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr15_-_75909289 1.255 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr11_+_48800357 1.254 ENSMUST00000020640.7
Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr2_+_32535724 1.247 ENSMUST00000133366.1
Fam102a
family with sequence similarity 102, member A
chr6_-_34317442 1.239 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr19_-_36919606 1.236 ENSMUST00000057337.7
Fgfbp3
fibroblast growth factor binding protein 3
chr5_-_33657889 1.234 ENSMUST00000019439.7
Tmem129
transmembrane protein 129
chr9_-_111271568 1.231 ENSMUST00000035079.3
Mlh1
mutL homolog 1 (E. coli)
chr17_-_48451510 1.229 ENSMUST00000024794.5
Tspo2
translocator protein 2
chr5_-_142906702 1.229 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
Actb


actin, beta


chr15_-_100424208 1.205 ENSMUST00000154331.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr15_-_75909319 1.203 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chr15_-_103537928 1.180 ENSMUST00000023133.6
Ppp1r1a
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr11_-_100939457 1.177 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr13_+_33964659 1.157 ENSMUST00000021843.5
ENSMUST00000058978.7
Nqo2

NAD(P)H dehydrogenase, quinone 2

chr11_+_22990519 1.156 ENSMUST00000173867.1
ENSMUST00000020562.4
Cct4

chaperonin containing Tcp1, subunit 4 (delta)

chr5_+_124629050 1.142 ENSMUST00000037865.8
Atp6v0a2
ATPase, H+ transporting, lysosomal V0 subunit A2
chr6_-_21852509 1.137 ENSMUST00000031678.3
Tspan12
tetraspanin 12
chrX_-_75130914 1.125 ENSMUST00000114091.1
Mpp1
membrane protein, palmitoylated
chrX_-_75130996 1.120 ENSMUST00000033775.2
Mpp1
membrane protein, palmitoylated
chr5_+_129787390 1.117 ENSMUST00000031402.8
Cct6a
chaperonin containing Tcp1, subunit 6a (zeta)
chr19_-_45749563 1.109 ENSMUST00000070215.7
Npm3
nucleoplasmin 3
chr19_-_12765447 1.095 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr15_+_85132080 1.086 ENSMUST00000023067.2
Ribc2
RIB43A domain with coiled-coils 2
chr7_+_35397046 1.076 ENSMUST00000079414.5
Cep89
centrosomal protein 89
chr18_-_24020749 1.074 ENSMUST00000066497.5
Zfp191
zinc finger protein 191
chr4_-_132422484 1.065 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chr15_-_73184840 1.037 ENSMUST00000044113.10
Ago2
argonaute RISC catalytic subunit 2
chrX_+_152233228 1.034 ENSMUST00000112588.2
ENSMUST00000082177.6
Kdm5c

lysine (K)-specific demethylase 5C

chr18_+_33794915 1.033 ENSMUST00000179138.1
2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr7_+_63444741 1.021 ENSMUST00000058476.7
Otud7a
OTU domain containing 7A
chr7_+_127471484 1.021 ENSMUST00000033095.8
Prr14
proline rich 14
chr4_-_139352538 1.017 ENSMUST00000102503.3
Mrto4
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr11_-_102697710 1.010 ENSMUST00000164506.2
ENSMUST00000092569.6
Ccdc43

coiled-coil domain containing 43

chr19_+_6909692 1.009 ENSMUST00000088257.7
Trmt112
tRNA methyltransferase 11-2
chr11_+_54866413 1.007 ENSMUST00000117710.1
Hint1
histidine triad nucleotide binding protein 1
chr14_-_26207041 1.004 ENSMUST00000022418.8
Tmem254b
transmembrane protein 254b
chr4_-_139352298 0.958 ENSMUST00000030513.6
ENSMUST00000155257.1
Mrto4

MRT4, mRNA turnover 4, homolog (S. cerevisiae)

chr10_+_80019621 0.913 ENSMUST00000043311.6
Hmha1
histocompatibility (minor) HA-1
chr13_+_91461050 0.896 ENSMUST00000004094.8
ENSMUST00000042122.8
Ssbp2

single-stranded DNA binding protein 2

chr18_+_33794882 0.894 ENSMUST00000146010.2
2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr12_+_37241633 0.889 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr14_+_75136326 0.883 ENSMUST00000145303.1
Lcp1
lymphocyte cytosolic protein 1
chr2_-_51934943 0.878 ENSMUST00000102767.1
ENSMUST00000102768.1
Rbm43

RNA binding motif protein 43

chr3_+_14863495 0.877 ENSMUST00000029076.4
Car3
carbonic anhydrase 3
chr11_-_80142164 0.872 ENSMUST00000050207.9
Tefm
transcription elongation factor, mitochondrial
chr18_+_65582281 0.860 ENSMUST00000183319.1
Zfp532
zinc finger protein 532
chr11_-_78751656 0.859 ENSMUST00000059468.4
Fam58b
family with sequence similarity 58, member B
chr5_-_129787175 0.853 ENSMUST00000031399.6
Psph
phosphoserine phosphatase
chr5_+_114786045 0.848 ENSMUST00000137519.1
Ankrd13a
ankyrin repeat domain 13a
chr3_+_95111013 0.844 ENSMUST00000009102.8
Vps72
vacuolar protein sorting 72 (yeast)
chr11_+_50376982 0.811 ENSMUST00000109142.1
Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
chr8_+_85492568 0.803 ENSMUST00000034136.5
Gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr19_+_6909722 0.770 ENSMUST00000116551.3
Trmt112
tRNA methyltransferase 11-2
chr9_+_15239045 0.765 ENSMUST00000034413.6
Vstm5
V-set and transmembrane domain containing 5
chr14_+_13284774 0.750 ENSMUST00000070323.5
Synpr
synaptoporin
chr8_-_110846770 0.730 ENSMUST00000042012.5
Sf3b3
splicing factor 3b, subunit 3
chr14_-_55643251 0.730 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
Tm9sf1




transmembrane 9 superfamily member 1




chr2_+_129800451 0.693 ENSMUST00000165413.2
ENSMUST00000166282.2
Stk35

serine/threonine kinase 35

chr12_-_111712909 0.681 ENSMUST00000160576.1
Bag5
BCL2-associated athanogene 5
chr2_+_93187574 0.652 ENSMUST00000090554.4
Trp53i11
transformation related protein 53 inducible protein 11
chr11_-_70969953 0.636 ENSMUST00000108530.1
ENSMUST00000035283.4
ENSMUST00000108531.1
Nup88


nucleoporin 88


chr1_+_55052770 0.633 ENSMUST00000027125.5
ENSMUST00000087617.4
Coq10b

coenzyme Q10 homolog B (S. cerevisiae)

chr15_-_75921463 0.629 ENSMUST00000053918.7
Pycrl
pyrroline-5-carboxylate reductase-like
chr7_+_101321703 0.598 ENSMUST00000174291.1
ENSMUST00000167888.2
ENSMUST00000172662.1
ENSMUST00000173270.1
ENSMUST00000174083.1
Stard10




START domain containing 10




chr14_+_30479565 0.587 ENSMUST00000022535.7
Dcp1a
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr3_+_84952146 0.583 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr19_-_40588338 0.564 ENSMUST00000176939.1
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr12_-_85288419 0.563 ENSMUST00000121930.1
Acyp1
acylphosphatase 1, erythrocyte (common) type
chr7_-_34654342 0.560 ENSMUST00000108069.1
Kctd15
potassium channel tetramerisation domain containing 15
chr2_+_84798828 0.534 ENSMUST00000102642.2
ENSMUST00000150325.1
Ube2l6

ubiquitin-conjugating enzyme E2L 6

chr19_-_40588453 0.531 ENSMUST00000025979.6
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr15_-_75909543 0.504 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chrX_-_10216437 0.501 ENSMUST00000115534.1
Rpgr
retinitis pigmentosa GTPase regulator
chr11_+_116532441 0.500 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
Sphk1



sphingosine kinase 1



chr7_+_127471009 0.497 ENSMUST00000133938.1
Prr14
proline rich 14
chrX_+_7841800 0.496 ENSMUST00000033494.9
ENSMUST00000115666.1
Otud5

OTU domain containing 5

chr2_-_154769932 0.491 ENSMUST00000184654.1
Gm14214
predicted gene 14214
chr14_+_79481164 0.486 ENSMUST00000040131.5
Elf1
E74-like factor 1
chr15_-_96699698 0.469 ENSMUST00000023099.6
Slc38a2
solute carrier family 38, member 2
chr6_+_14901344 0.459 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr7_-_126200474 0.448 ENSMUST00000168189.1
Xpo6
exportin 6
chr3_-_55055038 0.448 ENSMUST00000029368.2
Ccna1
cyclin A1
chr11_+_69914179 0.433 ENSMUST00000057884.5
Gps2
G protein pathway suppressor 2
chrX_+_7842056 0.426 ENSMUST00000115667.3
ENSMUST00000115668.3
ENSMUST00000115665.1
Otud5


OTU domain containing 5


chr11_-_45955465 0.421 ENSMUST00000011398.6
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr3_-_95106907 0.413 ENSMUST00000107233.2
Pip5k1a
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
chr17_+_35059035 0.411 ENSMUST00000007255.6
ENSMUST00000174493.1
Ddah2

dimethylarginine dimethylaminohydrolase 2

chr5_+_145114280 0.393 ENSMUST00000141602.1
Arpc1b
actin related protein 2/3 complex, subunit 1B
chr18_+_61555689 0.392 ENSMUST00000167187.1
Csnk1a1
casein kinase 1, alpha 1
chrX_-_7572843 0.384 ENSMUST00000132788.1
Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr4_+_95557494 0.375 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.5 6.1 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.5 4.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
1.4 4.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
1.3 4.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
1.1 3.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
1.1 3.2 GO:0043987 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) histone-serine phosphorylation(GO:0035404) histone H3-S10 phosphorylation(GO:0043987)
1.0 4.0 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.9 4.4 GO:0021764 amygdala development(GO:0021764)
0.9 6.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.8 3.3 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.8 3.3 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.8 3.3 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.7 8.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.7 2.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.7 3.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.7 2.8 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.7 4.0 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) macropinocytosis(GO:0044351)
0.7 5.3 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.6 3.2 GO:0060266 regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.6 3.1 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.6 7.8 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.6 1.8 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.6 2.3 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.5 2.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.5 2.1 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.5 1.4 GO:0006083 acetate metabolic process(GO:0006083)
0.5 1.4 GO:0038044 negative regulation of receptor biosynthetic process(GO:0010871) transforming growth factor-beta secretion(GO:0038044)
0.5 5.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.4 1.8 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.4 1.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.4 1.2 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.4 1.6 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.4 1.9 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.4 2.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.4 1.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.4 2.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4 2.5 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.3 1.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 1.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950) positive regulation of isotype switching to IgA isotypes(GO:0048298) meiotic metaphase plate congression(GO:0051311)
0.3 1.8 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.3 2.4 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.3 1.9 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.3 3.7 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.2 2.7 GO:1903975 regulation of glial cell migration(GO:1903975)
0.2 9.4 GO:0006270 DNA replication initiation(GO:0006270)
0.2 4.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 1.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 0.9 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.2 7.5 GO:0003016 respiratory system process(GO:0003016)
0.2 0.6 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.2 1.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 1.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 5.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 1.1 GO:1904851 positive regulation of establishment of protein localization to telomere(GO:1904851)
0.2 3.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 1.6 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 1.0 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.2 4.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.2 1.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 0.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 1.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 2.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 2.0 GO:0032060 bleb assembly(GO:0032060)
0.1 1.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 4.0 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 0.6 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.6 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 3.0 GO:0009299 mRNA transcription(GO:0009299)
0.1 0.9 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 2.5 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.7 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.1 2.2 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 0.3 GO:0001692 histamine metabolic process(GO:0001692)
0.1 2.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 2.0 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 4.2 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 11.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 1.2 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.1 2.3 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 1.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 2.9 GO:0070613 regulation of protein processing(GO:0070613)
0.1 2.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.5 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.5 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 1.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.4 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.2 GO:1904778 regulation of metaphase plate congression(GO:0090235) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 1.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.8 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 1.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.8 GO:0043486 histone exchange(GO:0043486)
0.0 3.9 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.4 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 2.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.4 GO:0006414 translational elongation(GO:0006414)
0.0 1.6 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.5 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 2.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.9 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
1.6 8.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.8 3.3 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.8 3.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.8 4.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.7 5.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.6 3.1 GO:0070826 paraferritin complex(GO:0070826)
0.5 2.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.5 3.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5 1.9 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.5 3.4 GO:0031298 replication fork protection complex(GO:0031298)
0.5 4.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.5 1.4 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.4 2.5 GO:0071817 MMXD complex(GO:0071817)
0.4 2.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 1.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 1.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 1.2 GO:0032389 MutLalpha complex(GO:0032389)
0.2 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 2.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 1.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 4.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 1.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.0 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 3.2 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 2.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 3.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 6.0 GO:0000793 condensed chromosome(GO:0000793)
0.0 4.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 4.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 3.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.6 GO:0043679 axon terminus(GO:0043679)
0.0 29.4 GO:0005615 extracellular space(GO:0005615)
0.0 1.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 3.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 5.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.3 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 3.1 GO:0030027 lamellipodium(GO:0030027)
0.0 6.2 GO:0005912 adherens junction(GO:0005912)
0.0 1.5 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 5.0 GO:0005813 centrosome(GO:0005813)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 9.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.4 4.3 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
1.0 6.1 GO:0050786 RAGE receptor binding(GO:0050786)
1.0 11.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.9 2.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.8 3.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.8 4.0 GO:0035174 histone serine kinase activity(GO:0035174)
0.8 2.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.7 2.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.7 3.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.6 3.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.6 8.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 2.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.5 2.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.5 5.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 4.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 4.4 GO:0008199 ferric iron binding(GO:0008199)
0.4 1.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.4 1.2 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.4 1.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.3 2.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 0.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 1.4 GO:0019960 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.3 1.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.3 1.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 3.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3 11.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 3.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 2.5 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.2 3.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.2 2.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 0.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 2.1 GO:0050693 LBD domain binding(GO:0050693)
0.2 0.6 GO:0004126 cytidine deaminase activity(GO:0004126) pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 1.5 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.2 0.9 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1 0.9 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 1.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 1.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.6 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 7.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 3.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 2.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.6 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.4 GO:2001069 glycogen binding(GO:2001069)
0.1 7.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 6.1 GO:0019955 cytokine binding(GO:0019955)
0.1 1.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 4.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 3.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 4.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.1 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 1.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 12.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.8 GO:0008483 transaminase activity(GO:0008483)
0.0 2.2 GO:0043022 ribosome binding(GO:0043022)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 4.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 3.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 9.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.2 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0 4.1 GO:0044325 ion channel binding(GO:0044325)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 3.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 3.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.1 GO:0051117 ATPase binding(GO:0051117)
0.0 0.6 GO:0019894 kinesin binding(GO:0019894)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.8 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 0.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 4.0 ST_STAT3_PATHWAY STAT3 Pathway
0.2 7.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 7.4 PID_BMP_PATHWAY BMP receptor signaling
0.1 5.8 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 19.7 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.3 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 9.0 PID_E2F_PATHWAY E2F transcription factor network
0.1 1.9 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 3.1 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 11.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.0 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.8 PID_ARF6_PATHWAY Arf6 signaling events
0.1 5.2 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.1 2.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.4 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.6 PID_MYC_PATHWAY C-MYC pathway
0.0 2.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 2.6 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.7 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 1.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 2.4 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_RAC1_PATHWAY RAC1 signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 5.6 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.3 6.5 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.3 3.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 4.0 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.3 7.8 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 7.4 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.2 4.6 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 6.6 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 2.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.2 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.1 2.0 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.1 3.3 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 6.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.4 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.5 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.8 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 3.1 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 4.8 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.5 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.4 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.7 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 7.4 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 4.0 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.5 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 2.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 7.3 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 6.1 REACTOME_TRANSLATION Genes involved in Translation
0.0 2.6 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 2.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 3.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 6.0 REACTOME_HEMOSTASIS Genes involved in Hemostasis
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis