Motif ID: Tfcp2l1

Z-value: 0.724


Transcription factors associated with Tfcp2l1:

Gene SymbolEntrez IDGene Name
Tfcp2l1 ENSMUSG00000026380.9 Tfcp2l1



Activity profile for motif Tfcp2l1.

activity profile for motif Tfcp2l1


Sorted Z-values histogram for motif Tfcp2l1

Sorted Z-values for motif Tfcp2l1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfcp2l1

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_98004634 1.584 ENSMUST00000131560.1
ENSMUST00000088355.5
 Col2a1

collagen, type II, alpha 1

chr15_-_98004695 1.292 ENSMUST00000023123.8
 Col2a1
collagen, type II, alpha 1
chr15_-_78718113 1.116 ENSMUST00000088592.4
 Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr12_+_14494561 1.107 ENSMUST00000052528.3
 Gm9847
predicted pseudogene 9847
chr6_-_84593810 1.102 ENSMUST00000077705.3
ENSMUST00000168003.2
 Cyp26b1

cytochrome P450, family 26, subfamily b, polypeptide 1

chr16_-_22161450 0.972 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr3_-_107518001 0.950 ENSMUST00000169449.1
ENSMUST00000029499.8
 Slc6a17

solute carrier family 6 (neurotransmitter transporter), member 17

chr9_+_44043384 0.785 ENSMUST00000114840.1
 Thy1
thymus cell antigen 1, theta
chr1_-_124045247 0.770 ENSMUST00000112603.2
 Dpp10
dipeptidylpeptidase 10
chr1_-_124045523 0.725 ENSMUST00000112606.1
 Dpp10
dipeptidylpeptidase 10
chr3_-_107517321 0.698 ENSMUST00000166892.1
 Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr3_-_101836223 0.574 ENSMUST00000061831.4
 Mab21l3
mab-21-like 3 (C. elegans)
chr6_-_28831747 0.523 ENSMUST00000062304.5
 Lrrc4
leucine rich repeat containing 4
chr2_+_121358591 0.512 ENSMUST00000000317.6
ENSMUST00000129130.1
 Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr2_+_172549581 0.492 ENSMUST00000030391.2
 Tfap2c
transcription factor AP-2, gamma
chr11_-_105937798 0.472 ENSMUST00000183493.1
 Cyb561
cytochrome b-561
chr1_+_5083105 0.471 ENSMUST00000044369.7
 Atp6v1h
ATPase, H+ transporting, lysosomal V1 subunit H
chr3_-_94658800 0.451 ENSMUST00000107277.1
ENSMUST00000006123.4
ENSMUST00000107279.2
 Tuft1


tuftelin 1


chr3_+_103575275 0.443 ENSMUST00000090697.4
 Syt6
synaptotagmin VI
chr1_-_132707304 0.431 ENSMUST00000043189.7
 Nfasc
neurofascin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.9 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.3 1.6 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 1.5 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.4 1.1 GO:0098528 terpenoid catabolic process(GO:0016115) skeletal muscle fiber differentiation(GO:0098528)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 0.8 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.8 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 0.5 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.5 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.5 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.3 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.3 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.4 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 2.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 1.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 0.8 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786) calcium-dependent phospholipid binding(GO:0005544)
0.2 0.5 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 NABA_COLLAGENS Genes encoding collagen proteins
0.1 0.8 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 ST_STAT3_PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage