Motif ID: Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2
Z-value: 1.169
Transcription factors associated with Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bhlhe41 | ENSMUSG00000030256.5 | Bhlhe41 |
| Srebf1 | ENSMUSG00000020538.9 | Srebf1 |
| Srebf2 | ENSMUSG00000022463.7 | Srebf2 |
| Tfeb | ENSMUSG00000023990.12 | Tfeb |
| Usf1 | ENSMUSG00000026641.7 | Usf1 |
| Usf2 | ENSMUSG00000058239.7 | Usf2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Srebf2 | mm10_v2_chr15_+_82147238_82147275 | 0.58 | 1.1e-02 | Click! |
| Tfeb | mm10_v2_chr17_+_47737030_47737107 | 0.52 | 2.5e-02 | Click! |
| Usf1 | mm10_v2_chr1_+_171411305_171411337 | 0.37 | 1.3e-01 | Click! |
| Usf2 | mm10_v2_chr7_-_30956742_30956803 | 0.37 | 1.3e-01 | Click! |
| Srebf1 | mm10_v2_chr11_-_60210410_60210465 | 0.34 | 1.7e-01 | Click! |
First level regulatory network of Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2
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Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 7.8 | GO:0043379 | memory T cell differentiation(GO:0043379) |
| 2.4 | 9.7 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
| 1.5 | 4.5 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 1.5 | 4.5 | GO:1904959 | elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959) |
| 1.3 | 3.8 | GO:0099547 | regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254) |
| 1.2 | 3.7 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 1.2 | 4.8 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 1.0 | 4.2 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.9 | 3.8 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
| 0.9 | 3.6 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 0.9 | 3.5 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
| 0.9 | 2.6 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.9 | 4.3 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.8 | 3.4 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.8 | 4.5 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.7 | 2.2 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
| 0.7 | 2.1 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 0.7 | 2.1 | GO:0043181 | vacuolar sequestering(GO:0043181) |
| 0.7 | 3.4 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.6 | 4.4 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.6 | 1.2 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) |
| 0.6 | 3.0 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.6 | 2.4 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.6 | 1.7 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.6 | 1.7 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
| 0.6 | 2.3 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 0.6 | 1.7 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
| 0.5 | 4.1 | GO:1903207 | neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) |
| 0.5 | 3.1 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.5 | 2.1 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055) |
| 0.5 | 2.4 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.5 | 1.4 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
| 0.5 | 3.8 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 0.5 | 13.8 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.4 | 1.7 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
| 0.4 | 4.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.4 | 1.2 | GO:0010871 | negative regulation of receptor biosynthetic process(GO:0010871) |
| 0.4 | 0.4 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.4 | 3.0 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.4 | 2.6 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.3 | 11.1 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.3 | 2.8 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
| 0.3 | 3.4 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.3 | 6.4 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.3 | 1.7 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.3 | 1.6 | GO:1903012 | positive regulation of bone development(GO:1903012) |
| 0.3 | 1.6 | GO:0042117 | monocyte activation(GO:0042117) |
| 0.3 | 3.6 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.3 | 2.2 | GO:0030242 | pexophagy(GO:0030242) |
| 0.3 | 2.9 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 0.3 | 1.3 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
| 0.3 | 3.5 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.3 | 2.2 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.3 | 0.9 | GO:1900453 | negative regulation of long term synaptic depression(GO:1900453) |
| 0.3 | 2.1 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.3 | 5.6 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.3 | 0.9 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
| 0.3 | 0.6 | GO:0048550 | negative regulation of pinocytosis(GO:0048550) |
| 0.3 | 12.5 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.3 | 1.1 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.3 | 1.4 | GO:0000019 | regulation of mitotic recombination(GO:0000019) |
| 0.3 | 1.0 | GO:0001956 | positive regulation of neurotransmitter secretion(GO:0001956) |
| 0.3 | 1.8 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.3 | 0.8 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.3 | 1.8 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.2 | 0.5 | GO:0070625 | zymogen granule exocytosis(GO:0070625) |
| 0.2 | 4.1 | GO:0072112 | renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
| 0.2 | 1.5 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.2 | 1.9 | GO:0015074 | DNA integration(GO:0015074) |
| 0.2 | 6.4 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.2 | 2.8 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.2 | 0.5 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.2 | 1.4 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.2 | 0.5 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.2 | 0.7 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.2 | 0.7 | GO:0035963 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) |
| 0.2 | 2.9 | GO:0043084 | penile erection(GO:0043084) |
| 0.2 | 2.4 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.2 | 9.1 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.2 | 1.5 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.2 | 0.6 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
| 0.2 | 0.8 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.2 | 0.8 | GO:0097494 | regulation of vesicle size(GO:0097494) |
| 0.2 | 2.4 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.2 | 1.4 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.2 | 3.0 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.2 | 1.0 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.2 | 0.8 | GO:0021586 | pons maturation(GO:0021586) |
| 0.2 | 0.7 | GO:0060083 | smooth muscle contraction involved in micturition(GO:0060083) |
| 0.2 | 1.1 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 0.2 | 2.2 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.2 | 0.9 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.2 | 0.5 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.2 | 2.5 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.2 | 0.5 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
| 0.2 | 0.5 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.2 | 1.2 | GO:1903441 | protein localization to ciliary membrane(GO:1903441) |
| 0.2 | 2.7 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
| 0.2 | 1.7 | GO:0071472 | cellular response to salt stress(GO:0071472) |
| 0.2 | 2.2 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.2 | 2.8 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.2 | 2.6 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
| 0.2 | 11.8 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.2 | 2.3 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.2 | 1.1 | GO:0035188 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.2 | 1.1 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.2 | 1.5 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.1 | 1.8 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
| 0.1 | 1.2 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.1 | 3.7 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.1 | 1.3 | GO:1900244 | positive regulation of synaptic vesicle endocytosis(GO:1900244) |
| 0.1 | 1.3 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.1 | 1.0 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.1 | 0.7 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
| 0.1 | 0.7 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
| 0.1 | 0.3 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.1 | 1.0 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.1 | 1.9 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.1 | 1.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.3 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.1 | 0.4 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.1 | 0.8 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.1 | 1.6 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
| 0.1 | 4.7 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.1 | 0.6 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) |
| 0.1 | 0.4 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.1 | 0.9 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.1 | 3.6 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.1 | 0.7 | GO:1903551 | regulation of extracellular exosome assembly(GO:1903551) |
| 0.1 | 5.0 | GO:0045214 | sarcomere organization(GO:0045214) |
| 0.1 | 0.9 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.1 | 1.9 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 0.4 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 0.1 | 0.2 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
| 0.1 | 2.6 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.1 | 1.3 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.1 | 0.3 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.1 | 0.3 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.1 | 0.3 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 0.1 | 0.9 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 0.9 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
| 0.1 | 0.4 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.1 | 0.3 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.1 | 0.3 | GO:0060971 | embryonic heart tube left/right pattern formation(GO:0060971) |
| 0.1 | 0.4 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
| 0.1 | 0.4 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
| 0.1 | 1.1 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 0.1 | 1.7 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.1 | 0.3 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.1 | 15.4 | GO:0008643 | carbohydrate transport(GO:0008643) |
| 0.1 | 0.8 | GO:2000480 | regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.3 | GO:0019530 | taurine metabolic process(GO:0019530) |
| 0.1 | 0.2 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 0.1 | 0.4 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.1 | 0.8 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
| 0.1 | 3.4 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.1 | 1.3 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
| 0.1 | 0.4 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.1 | 1.3 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.1 | 0.8 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.1 | 1.0 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.1 | 0.2 | GO:0043686 | co-translational protein modification(GO:0043686) |
| 0.1 | 1.0 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 0.4 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.1 | 1.2 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.1 | 0.3 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 0.1 | 5.2 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.1 | 0.4 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.1 | 0.4 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.1 | 0.7 | GO:1901387 | positive regulation of voltage-gated calcium channel activity(GO:1901387) |
| 0.1 | 0.3 | GO:0031000 | response to caffeine(GO:0031000) |
| 0.1 | 0.6 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.1 | 3.2 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
| 0.1 | 1.3 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.1 | 0.3 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.1 | 4.1 | GO:0030203 | glycosaminoglycan metabolic process(GO:0030203) |
| 0.1 | 5.9 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.1 | 0.5 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 1.1 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.1 | 0.2 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.1 | 1.1 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.1 | 1.9 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.1 | 0.4 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 1.3 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 2.0 | GO:0048713 | regulation of oligodendrocyte differentiation(GO:0048713) |
| 0.1 | 0.1 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 0.1 | 0.4 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.1 | 0.1 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 0.1 | 2.1 | GO:0019432 | triglyceride biosynthetic process(GO:0019432) |
| 0.1 | 1.7 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.1 | 0.2 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.1 | 0.6 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.1 | 0.7 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.1 | 0.2 | GO:0019858 | cytosine metabolic process(GO:0019858) |
| 0.1 | 1.0 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.1 | 0.6 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.1 | 0.2 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.1 | 0.2 | GO:0045350 | interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.1 | 0.3 | GO:0048069 | eye pigmentation(GO:0048069) |
| 0.1 | 0.5 | GO:0006817 | phosphate ion transport(GO:0006817) |
| 0.1 | 0.5 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.1 | 0.4 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126) |
| 0.1 | 0.6 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.1 | 0.2 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 0.1 | 0.6 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 1.8 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.1 | 1.1 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.1 | 2.7 | GO:0007492 | endoderm development(GO:0007492) |
| 0.1 | 0.2 | GO:2000110 | protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.1 | 0.9 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.1 | 0.5 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.1 | 0.1 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) |
| 0.1 | 0.1 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.1 | 0.3 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.1 | 1.5 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.1 | 0.5 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.1 | 0.4 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 1.4 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.1 | 0.2 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
| 0.1 | 0.3 | GO:0002544 | chronic inflammatory response(GO:0002544) |
| 0.1 | 1.3 | GO:0035909 | aorta morphogenesis(GO:0035909) |
| 0.1 | 0.7 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.1 | 0.3 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 6.3 | GO:0007596 | blood coagulation(GO:0007596) |
| 0.0 | 1.0 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
| 0.0 | 0.1 | GO:0071873 | response to norepinephrine(GO:0071873) |
| 0.0 | 2.2 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.4 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.0 | 0.3 | GO:0090148 | membrane fission(GO:0090148) |
| 0.0 | 0.3 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.0 | 0.1 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.0 | 0.1 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) |
| 0.0 | 0.3 | GO:0051503 | adenine nucleotide transport(GO:0051503) |
| 0.0 | 0.5 | GO:0006681 | galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) |
| 0.0 | 0.1 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
| 0.0 | 0.8 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.8 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.0 | 0.4 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.0 | 2.0 | GO:0045839 | negative regulation of mitotic nuclear division(GO:0045839) |
| 0.0 | 1.4 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.0 | 0.5 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.0 | 0.3 | GO:0030166 | proteoglycan biosynthetic process(GO:0030166) |
| 0.0 | 0.5 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
| 0.0 | 0.2 | GO:0014842 | regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857) |
| 0.0 | 0.2 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 0.3 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
| 0.0 | 1.5 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.0 | 0.0 | GO:0014043 | regulation of neuron maturation(GO:0014041) negative regulation of neuron maturation(GO:0014043) |
| 0.0 | 0.3 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.0 | 0.1 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
| 0.0 | 0.3 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) |
| 0.0 | 0.2 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.0 | 1.1 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 0.2 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 0.0 | 0.1 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
| 0.0 | 0.3 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 0.4 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.0 | 1.0 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.0 | 0.2 | GO:0051255 | spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256) |
| 0.0 | 0.3 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 0.0 | 0.4 | GO:1901017 | negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
| 0.0 | 0.3 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.0 | 0.1 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.0 | 0.8 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.0 | 0.2 | GO:0044539 | long-chain fatty acid import(GO:0044539) |
| 0.0 | 2.7 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.0 | 0.1 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.0 | 0.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.0 | 0.3 | GO:0014044 | Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.0 | 2.1 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 0.2 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.2 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.0 | 0.2 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.0 | 0.2 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.0 | 0.4 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.2 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.0 | 0.2 | GO:0030049 | muscle filament sliding(GO:0030049) |
| 0.0 | 0.4 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 0.2 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.0 | 0.2 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.0 | 0.1 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.5 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 0.0 | 0.1 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.0 | 0.0 | GO:0033603 | positive regulation of dopamine secretion(GO:0033603) |
| 0.0 | 0.4 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.0 | 0.3 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.0 | 0.1 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.0 | 0.0 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
| 0.0 | 0.2 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.0 | 2.7 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 0.1 | GO:0035247 | peptidyl-arginine omega-N-methylation(GO:0035247) |
| 0.0 | 0.8 | GO:0032414 | positive regulation of ion transmembrane transporter activity(GO:0032414) |
| 0.0 | 0.0 | GO:0003357 | noradrenergic neuron differentiation(GO:0003357) |
| 0.0 | 0.1 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
| 0.0 | 0.3 | GO:0046548 | retinal rod cell development(GO:0046548) |
| 0.0 | 0.3 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.1 | GO:0034312 | diol biosynthetic process(GO:0034312) |
| 0.0 | 0.2 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 0.2 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.4 | GO:0021513 | spinal cord dorsal/ventral patterning(GO:0021513) |
| 0.0 | 0.2 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 0.1 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.0 | 0.5 | GO:0051646 | mitochondrion localization(GO:0051646) |
| 0.0 | 0.1 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.1 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
| 0.0 | 0.2 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.0 | 0.1 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.0 | 0.2 | GO:0050770 | regulation of axonogenesis(GO:0050770) |
| 0.0 | 0.1 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
| 0.0 | 0.1 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.0 | 0.3 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 0.1 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.0 | 0.0 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.0 | 0.1 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.0 | 0.5 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 0.1 | GO:0006598 | polyamine catabolic process(GO:0006598) |
| 0.0 | 1.2 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 0.1 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.6 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.2 | GO:0015816 | glycine transport(GO:0015816) |
| 0.0 | 0.2 | GO:0046718 | viral entry into host cell(GO:0046718) |
| 0.0 | 0.0 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.0 | 0.1 | GO:0016093 | polyprenol metabolic process(GO:0016093) |
| 0.0 | 0.9 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity(GO:0051092) |
| 0.0 | 0.4 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.0 | 0.3 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.1 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.0 | 0.3 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.0 | GO:0070162 | adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164) |
| 0.0 | 0.1 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
| 0.0 | 0.1 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 1.4 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.0 | 0.0 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.0 | 0.1 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.0 | 0.0 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 0.0 | 0.0 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.1 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 5.6 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 1.8 | 7.1 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 1.4 | 9.7 | GO:0033263 | CORVET complex(GO:0033263) |
| 1.3 | 5.3 | GO:0019034 | viral replication complex(GO:0019034) |
| 1.2 | 3.6 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 1.2 | 3.5 | GO:0000802 | transverse filament(GO:0000802) |
| 0.8 | 7.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.7 | 3.0 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
| 0.7 | 3.4 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.6 | 3.0 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.6 | 1.8 | GO:0098835 | presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
| 0.5 | 6.7 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.5 | 4.7 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.5 | 1.4 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.5 | 3.2 | GO:0070695 | FHF complex(GO:0070695) |
| 0.4 | 3.6 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.4 | 3.8 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.4 | 0.8 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.4 | 3.7 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.3 | 3.4 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.3 | 1.6 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 0.3 | 1.8 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.3 | 1.2 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.3 | 1.7 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.3 | 0.6 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.3 | 1.9 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.3 | 4.2 | GO:0043196 | varicosity(GO:0043196) |
| 0.3 | 0.8 | GO:0000801 | central element(GO:0000801) |
| 0.3 | 0.8 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.2 | 1.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.2 | 2.1 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.2 | 2.0 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.2 | 1.3 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.2 | 1.3 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.2 | 2.9 | GO:0043203 | axon hillock(GO:0043203) |
| 0.2 | 2.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.2 | 0.4 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.2 | 1.7 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.2 | 1.3 | GO:0071203 | WASH complex(GO:0071203) |
| 0.2 | 1.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 1.3 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.2 | 3.5 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.2 | 0.8 | GO:0097361 | CIA complex(GO:0097361) |
| 0.2 | 1.7 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.2 | 1.5 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.1 | 2.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.4 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 0.1 | 2.2 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.1 | 4.5 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 0.6 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 1.7 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.1 | 1.7 | GO:0030057 | desmosome(GO:0030057) |
| 0.1 | 0.6 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.1 | 1.9 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.1 | 0.4 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.1 | 2.1 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 0.4 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.1 | 1.0 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 1.8 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 3.5 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.1 | 1.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.1 | 0.9 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.1 | 0.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 2.6 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 2.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 1.1 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.4 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.1 | 0.4 | GO:0044308 | axonal spine(GO:0044308) |
| 0.1 | 3.7 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 1.2 | GO:0098984 | asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984) |
| 0.1 | 0.5 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 1.3 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 2.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 1.0 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 1.7 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.1 | 0.6 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.1 | 1.4 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.1 | 0.8 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 0.3 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.1 | 0.6 | GO:0090543 | Flemming body(GO:0090543) |
| 0.1 | 1.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 12.0 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 0.6 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 17.0 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 3.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 0.4 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.1 | 12.6 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.1 | 0.2 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 1.7 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 0.2 | GO:0031673 | H zone(GO:0031673) |
| 0.1 | 0.5 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 0.3 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 0.4 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.1 | 0.3 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.0 | 4.2 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 0.2 | GO:0051286 | cell tip(GO:0051286) |
| 0.0 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 1.0 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 0.9 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 2.0 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.2 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.8 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 3.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.2 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.0 | 1.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 1.2 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.2 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.2 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 0.3 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.0 | 0.2 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.0 | 0.1 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.0 | 0.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 1.1 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 1.0 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 0.7 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 7.7 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.0 | 0.7 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 2.6 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.0 | 7.8 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 0.2 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.4 | GO:0044754 | secondary lysosome(GO:0005767) autolysosome(GO:0044754) |
| 0.0 | 0.2 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 2.7 | GO:0016528 | sarcoplasm(GO:0016528) |
| 0.0 | 1.1 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.0 | 0.1 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 0.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.1 | GO:0042581 | specific granule(GO:0042581) |
| 0.0 | 1.5 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.2 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.2 | GO:0098827 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
| 0.0 | 0.8 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.0 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.0 | 0.2 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 2.0 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.1 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 0.1 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
| 0.0 | 0.5 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.2 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.1 | GO:0031415 | NatA complex(GO:0031415) |
| 0.0 | 0.1 | GO:0070187 | telosome(GO:0070187) |
| 0.0 | 0.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 7.5 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 0.5 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.0 | 1.2 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 0.4 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 1.9 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 0.2 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.0 | 0.0 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.0 | 0.1 | GO:1904949 | ATPase complex(GO:1904949) |
| 0.0 | 1.3 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.2 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.9 | GO:0030659 | cytoplasmic vesicle membrane(GO:0030659) |
| 0.0 | 0.7 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 1.5 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.2 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.9 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.0 | GO:0005883 | neurofilament(GO:0005883) |
| 0.0 | 0.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 9.7 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 1.5 | 4.5 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
| 1.2 | 3.6 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.8 | 5.1 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.8 | 19.2 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
| 0.8 | 4.8 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.7 | 2.1 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.7 | 4.9 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.7 | 11.1 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.7 | 3.4 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.6 | 2.6 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
| 0.6 | 1.8 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.6 | 1.7 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
| 0.6 | 4.0 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.6 | 4.0 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.5 | 2.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.5 | 2.8 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.5 | 1.8 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.5 | 9.9 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.4 | 5.2 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.4 | 2.1 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.4 | 3.4 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.4 | 3.0 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.4 | 4.5 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.4 | 1.6 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.4 | 1.2 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.4 | 1.6 | GO:0070888 | E-box binding(GO:0070888) |
| 0.4 | 1.5 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.4 | 4.2 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.3 | 1.0 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.3 | 1.3 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
| 0.3 | 1.6 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.3 | 1.9 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.3 | 2.8 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.3 | 3.9 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.3 | 6.9 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.3 | 1.5 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.3 | 5.7 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.3 | 1.7 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.3 | 0.9 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.3 | 0.8 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.3 | 2.4 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.3 | 1.1 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 0.3 | 2.0 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.3 | 0.8 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.2 | 4.0 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.2 | 0.7 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 0.2 | 6.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.2 | 3.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.2 | 1.1 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.2 | 1.1 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.2 | 1.5 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.2 | 2.3 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 0.2 | 0.6 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 0.2 | 1.3 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.2 | 0.8 | GO:0051378 | serotonin binding(GO:0051378) |
| 0.2 | 2.9 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.2 | 0.8 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
| 0.2 | 1.0 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.2 | 0.2 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.2 | 0.5 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.2 | 0.7 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.2 | 6.0 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.2 | 2.1 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.2 | 4.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.2 | 1.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.2 | 0.5 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.2 | 3.0 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.2 | 1.5 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.2 | 1.0 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.2 | 1.5 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.2 | 0.6 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.2 | 2.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 1.9 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.2 | 3.5 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
| 0.2 | 1.1 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.2 | 4.6 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.2 | 2.1 | GO:0031005 | filamin binding(GO:0031005) |
| 0.2 | 0.8 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.1 | 0.4 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.1 | 0.4 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.1 | 0.8 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 0.1 | 0.6 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.1 | 1.4 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.1 | 0.8 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.1 | 0.4 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.1 | 1.1 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.1 | 0.4 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.1 | 1.8 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 0.8 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 0.9 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
| 0.1 | 0.5 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.1 | 6.2 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 2.8 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 1.0 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 2.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.3 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.1 | 1.4 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 1.0 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 0.8 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 2.4 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 0.3 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.1 | 0.7 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.1 | 3.0 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 0.1 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.1 | 0.3 | GO:0036004 | GAF domain binding(GO:0036004) |
| 0.1 | 0.4 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
| 0.1 | 0.7 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.4 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
| 0.1 | 4.0 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 7.5 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 2.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 0.3 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 0.5 | GO:0009374 | biotin binding(GO:0009374) |
| 0.1 | 0.4 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 0.9 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 3.9 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 2.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 0.2 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.1 | 0.2 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.1 | 0.2 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.1 | 1.3 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.1 | 0.2 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.1 | 0.4 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 4.3 | GO:0017022 | myosin binding(GO:0017022) |
| 0.1 | 5.1 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.1 | 0.9 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.1 | 0.5 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 0.3 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.1 | 0.3 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.1 | 1.7 | GO:0008373 | sialyltransferase activity(GO:0008373) |
| 0.1 | 0.6 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.1 | 1.0 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.1 | 2.6 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
| 0.1 | 3.2 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.1 | 0.3 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.1 | 1.2 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.1 | 0.6 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.1 | 0.3 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
| 0.1 | 0.2 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
| 0.1 | 0.7 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 0.3 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.1 | 0.3 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.1 | 0.4 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.0 | 0.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.0 | 0.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.0 | 1.0 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 0.4 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 0.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.0 | 0.3 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.0 | 22.8 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.4 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.0 | 0.1 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
| 0.0 | 1.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 4.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.9 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 5.4 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.0 | 0.1 | GO:0019002 | GMP binding(GO:0019002) |
| 0.0 | 0.2 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.0 | 3.0 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.8 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.1 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.0 | 0.3 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.2 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.0 | 0.3 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.1 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.0 | 0.1 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.0 | 0.2 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 1.0 | GO:0043394 | proteoglycan binding(GO:0043394) |
| 0.0 | 0.1 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
| 0.0 | 0.1 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 0.0 | 0.1 | GO:0043398 | HLH domain binding(GO:0043398) |
| 0.0 | 0.1 | GO:0004980 | melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.0 | 3.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.5 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.1 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.0 | 0.7 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 2.8 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 0.2 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.0 | 0.4 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.0 | 0.1 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.0 | 0.7 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.1 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 0.2 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.0 | 0.2 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.0 | 0.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.1 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.0 | 0.3 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.1 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.0 | 0.1 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
| 0.0 | 2.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.7 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.5 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.0 | 0.9 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.6 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 1.0 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.0 | 0.4 | GO:1901505 | carbohydrate derivative transporter activity(GO:1901505) |
| 0.0 | 0.1 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
| 0.0 | 0.2 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.3 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.2 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.2 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.0 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
| 0.0 | 0.9 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 0.0 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.0 | 0.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.2 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 0.2 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.0 | 0.2 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.1 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.0 | 2.4 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.1 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.0 | 1.1 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.0 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.0 | 0.2 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.0 | 0.1 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 0.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.9 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.0 | 0.1 | GO:0004659 | prenyltransferase activity(GO:0004659) |
| 0.0 | 1.5 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.2 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 1.2 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.0 | GO:0035242 | histone-arginine N-methyltransferase activity(GO:0008469) arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.0 | 0.1 | GO:0016229 | steroid dehydrogenase activity(GO:0016229) |
| 0.0 | 0.1 | GO:0016215 | acyl-CoA desaturase activity(GO:0016215) |
| 0.0 | 0.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.0 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.0 | 0.3 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.3 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.1 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.0 | 0.1 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.0 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.7 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.1 | 7.7 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
| 0.1 | 0.6 | PID_IFNG_PATHWAY | IFN-gamma pathway |
| 0.1 | 3.2 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.1 | 6.2 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.1 | 1.9 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.1 | 1.3 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 6.4 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.1 | 2.3 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
| 0.1 | 1.2 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.1 | 1.0 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.1 | 1.0 | PID_ATM_PATHWAY | ATM pathway |
| 0.1 | 0.4 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
| 0.1 | 2.0 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.7 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 1.0 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 2.0 | PID_P73PATHWAY | p73 transcription factor network |
| 0.0 | 2.9 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.0 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
| 0.0 | 1.7 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.4 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.0 | 1.9 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.0 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.0 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.0 | 0.9 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.0 | 1.3 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.0 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
| 0.0 | 0.2 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.4 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 1.2 | PID_ERBB1_DOWNSTREAM_PATHWAY | ErbB1 downstream signaling |
| 0.0 | 0.8 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 0.1 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 0.1 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
| 0.0 | 0.2 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.7 | PID_AVB3_INTEGRIN_PATHWAY | Integrins in angiogenesis |
| 0.0 | 0.1 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 0.4 | REACTOME_REGULATION_OF_INSULIN_SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.3 | 4.1 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.3 | 7.4 | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.3 | 2.6 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.3 | 3.7 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 2.2 | REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS | Genes involved in Acetylcholine Binding And Downstream Events |
| 0.2 | 5.1 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.2 | 4.0 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.2 | 1.2 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
| 0.2 | 2.3 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.2 | 3.6 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 0.6 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.2 | 4.3 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 1.8 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 8.6 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 2.9 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 4.9 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 5.2 | REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ | Genes involved in Formation of RNA Pol II elongation complex |
| 0.1 | 1.6 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.1 | 1.2 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
| 0.1 | 3.3 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 3.8 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 1.4 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.1 | 2.7 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.1 | 1.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 1.0 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.1 | 0.9 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.1 | 0.8 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.1 | 1.2 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 0.9 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.1 | 0.5 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.1 | 0.2 | REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.1 | 0.5 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 1.1 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 1.7 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 5.8 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 1.0 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.1 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 1.0 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.8 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.0 | 1.1 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 0.8 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 0.7 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.7 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.4 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.7 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.3 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.4 | REACTOME_MEIOSIS | Genes involved in Meiosis |
| 0.0 | 2.8 | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.0 | 0.7 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 1.0 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.4 | REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
| 0.0 | 0.5 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.4 | REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS | Genes involved in Prolonged ERK activation events |
| 0.0 | 0.8 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.7 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 0.5 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.4 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.0 | 0.7 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.2 | REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.0 | 0.4 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.1 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.4 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 0.9 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.2 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
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