Motif ID: Thra

Z-value: 0.760


Transcription factors associated with Thra:

Gene SymbolEntrez IDGene Name
Thra ENSMUSG00000058756.7 Thra

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Thramm10_v2_chr11_+_98741805_98741816-0.735.8e-04Click!


Activity profile for motif Thra.

activity profile for motif Thra


Sorted Z-values histogram for motif Thra

Sorted Z-values for motif Thra



Network of associatons between targets according to the STRING database.



First level regulatory network of Thra

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_116422858 2.555 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr18_+_57142782 2.154 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr13_+_44729794 1.822 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr4_+_44300876 1.563 ENSMUST00000045607.5
Melk
maternal embryonic leucine zipper kinase
chr1_+_84839833 1.523 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr14_-_118052235 1.404 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr10_-_92162753 1.381 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr4_-_137766474 1.322 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr17_-_32388885 1.107 ENSMUST00000087703.5
ENSMUST00000170603.1
Wiz

widely-interspaced zinc finger motifs

chr12_+_79029150 1.061 ENSMUST00000039928.5
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr12_+_112678803 1.025 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
Zbtb42


zinc finger and BTB domain containing 42


chr14_-_118706180 1.016 ENSMUST00000036554.6
ENSMUST00000166646.1
Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr4_-_135272798 0.920 ENSMUST00000037099.8
Clic4
chloride intracellular channel 4 (mitochondrial)
chr11_+_69965396 0.906 ENSMUST00000018713.6
Cldn7
claudin 7
chr6_+_113531675 0.883 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr1_-_84839304 0.882 ENSMUST00000027421.6
Trip12
thyroid hormone receptor interactor 12
chr6_+_120836201 0.881 ENSMUST00000009256.2
Bcl2l13
BCL2-like 13 (apoptosis facilitator)
chr11_+_40733936 0.843 ENSMUST00000127382.1
Nudcd2
NudC domain containing 2
chrX_-_143827391 0.840 ENSMUST00000087316.5
Capn6
calpain 6
chr1_-_163994767 0.837 ENSMUST00000097493.3
ENSMUST00000045876.6
BC055324

cDNA sequence BC055324

chr14_+_25459267 0.825 ENSMUST00000007961.8
Zmiz1
zinc finger, MIZ-type containing 1
chr5_-_74065736 0.824 ENSMUST00000145016.1
Usp46
ubiquitin specific peptidase 46
chr13_+_44729535 0.822 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr1_-_170306332 0.809 ENSMUST00000179801.1
Gm7694
predicted gene 7694
chr1_+_131910458 0.806 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr16_-_23520579 0.800 ENSMUST00000089883.5
Masp1
mannan-binding lectin serine peptidase 1
chr2_+_131186942 0.793 ENSMUST00000028804.8
ENSMUST00000079857.8
Cdc25b

cell division cycle 25B

chr15_-_77842133 0.793 ENSMUST00000016771.6
Myh9
myosin, heavy polypeptide 9, non-muscle
chr17_+_85620816 0.762 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr13_+_94875600 0.720 ENSMUST00000022195.10
Otp
orthopedia homolog (Drosophila)
chrX_-_102252154 0.718 ENSMUST00000050551.3
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr11_+_40733639 0.713 ENSMUST00000020578.4
Nudcd2
NudC domain containing 2
chr10_+_93641041 0.702 ENSMUST00000020204.4
Ntn4
netrin 4
chr8_+_120537423 0.697 ENSMUST00000118136.1
Gse1
genetic suppressor element 1
chr12_-_111672290 0.682 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr3_-_52104891 0.671 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr10_+_80148263 0.666 ENSMUST00000099492.3
ENSMUST00000042057.5
Midn

midnolin

chr12_-_98737405 0.630 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr5_-_134946917 0.629 ENSMUST00000051401.2
Cldn4
claudin 4
chr14_-_70207637 0.607 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chr1_+_74791516 0.604 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr10_+_88147061 0.599 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr5_+_110839973 0.598 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr2_+_129592818 0.567 ENSMUST00000153491.1
ENSMUST00000161620.1
ENSMUST00000179001.1
Sirpa


signal-regulatory protein alpha


chr11_-_106272927 0.567 ENSMUST00000021052.9
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chrX_-_75843185 0.550 ENSMUST00000137192.1
Pls3
plastin 3 (T-isoform)
chr1_+_160195215 0.549 ENSMUST00000135680.1
ENSMUST00000097193.2
Mrps14

mitochondrial ribosomal protein S14

chr14_+_25459206 0.546 ENSMUST00000162645.1
Zmiz1
zinc finger, MIZ-type containing 1
chr7_-_35802968 0.536 ENSMUST00000061586.4
Zfp507
zinc finger protein 507
chr5_+_53590215 0.514 ENSMUST00000037618.6
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chrX_+_169685191 0.507 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr14_-_20730327 0.505 ENSMUST00000047490.5
Ndst2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr2_+_155382186 0.504 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr12_+_86678685 0.501 ENSMUST00000021681.3
Vash1
vasohibin 1
chr8_-_72443772 0.497 ENSMUST00000019876.5
Calr3
calreticulin 3
chr10_+_88146992 0.497 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr7_+_27258725 0.494 ENSMUST00000079258.6
Numbl
numb-like
chr6_+_83137089 0.490 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chrX_-_53269020 0.484 ENSMUST00000114838.1
Fam122b
family with sequence similarity 122, member B
chr19_-_46044914 0.479 ENSMUST00000026252.7
Ldb1
LIM domain binding 1
chr6_+_134035691 0.476 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr4_-_129227883 0.472 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr10_-_13324250 0.471 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2
chr8_-_105707933 0.465 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr7_+_35802593 0.457 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr7_-_102250086 0.449 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr4_-_140774196 0.445 ENSMUST00000026381.6
Padi4
peptidyl arginine deiminase, type IV
chr13_-_99900645 0.441 ENSMUST00000022150.6
Cartpt
CART prepropeptide
chr10_-_13324160 0.436 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr2_+_112265809 0.435 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr16_+_32431225 0.430 ENSMUST00000115140.1
Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr7_+_102229999 0.425 ENSMUST00000120119.1
Pgap2
post-GPI attachment to proteins 2
chr19_+_8764934 0.417 ENSMUST00000184663.1
Nxf1
nuclear RNA export factor 1
chr10_-_88146867 0.411 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chrX_-_75843063 0.404 ENSMUST00000114057.1
Pls3
plastin 3 (T-isoform)
chr3_+_96172327 0.400 ENSMUST00000076372.4
Sf3b4
splicing factor 3b, subunit 4
chr2_+_157279026 0.397 ENSMUST00000116380.2
Rpn2
ribophorin II
chr9_+_107576915 0.376 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
Hyal1



hyaluronoglucosaminidase 1



chr10_+_126978690 0.375 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chrX_+_73716712 0.373 ENSMUST00000114461.2
Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr7_-_141214080 0.369 ENSMUST00000026573.5
ENSMUST00000170841.1
1600016N20Rik

RIKEN cDNA 1600016N20 gene

chr2_+_157279065 0.364 ENSMUST00000029171.5
Rpn2
ribophorin II
chr2_+_129592914 0.363 ENSMUST00000103203.1
Sirpa
signal-regulatory protein alpha
chr11_-_40733373 0.359 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr15_-_98165560 0.346 ENSMUST00000123922.1
Asb8
ankyrin repeat and SOCS box-containing 8
chr14_+_20929416 0.339 ENSMUST00000022369.7
Vcl
vinculin
chr4_-_126202583 0.339 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
Thrap3


thyroid hormone receptor associated protein 3


chr7_-_126475082 0.324 ENSMUST00000032978.6
Sh2b1
SH2B adaptor protein 1
chr2_+_145785980 0.319 ENSMUST00000110005.1
ENSMUST00000094480.4
Rin2

Ras and Rab interactor 2

chr6_-_86526164 0.318 ENSMUST00000053015.5
Pcbp1
poly(rC) binding protein 1
chr17_+_74717743 0.310 ENSMUST00000024882.6
Ttc27
tetratricopeptide repeat domain 27
chr6_+_91157373 0.309 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr11_+_97315716 0.308 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr3_-_96172384 0.306 ENSMUST00000180958.1
Gm17690
predicted gene, 17690
chr7_-_100514800 0.306 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr15_-_78529617 0.302 ENSMUST00000023075.8
C1qtnf6
C1q and tumor necrosis factor related protein 6
chr15_-_98165613 0.294 ENSMUST00000143400.1
Asb8
ankyrin repeat and SOCS box-containing 8
chr14_-_16243309 0.293 ENSMUST00000112625.1
Oxsm
3-oxoacyl-ACP synthase, mitochondrial
chr14_+_21500879 0.290 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr7_+_102267795 0.275 ENSMUST00000033289.4
Stim1
stromal interaction molecule 1
chr16_+_32430895 0.271 ENSMUST00000115137.1
ENSMUST00000079791.4
Pcyt1a

phosphate cytidylyltransferase 1, choline, alpha isoform

chr16_+_32431020 0.264 ENSMUST00000104893.2
Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr7_-_122101735 0.261 ENSMUST00000139456.1
ENSMUST00000106471.2
ENSMUST00000123296.1
ENSMUST00000033157.3
Ndufab1



NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1



chr5_+_121795034 0.261 ENSMUST00000162327.1
Atxn2
ataxin 2
chr12_+_78861693 0.259 ENSMUST00000071230.7
Eif2s1
eukaryotic translation initiation factor 2, subunit 1 alpha
chr6_-_71823805 0.256 ENSMUST00000065103.2
Mrpl35
mitochondrial ribosomal protein L35
chr5_+_32863700 0.256 ENSMUST00000149350.1
ENSMUST00000118698.1
ENSMUST00000150130.1
ENSMUST00000087897.4
ENSMUST00000119705.1
ENSMUST00000125574.1
ENSMUST00000049780.6
Depdc5






DEP domain containing 5






chr14_-_55758458 0.254 ENSMUST00000001497.7
Cideb
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr7_+_19228334 0.254 ENSMUST00000063976.8
Opa3
optic atrophy 3
chr1_+_131827977 0.254 ENSMUST00000086559.6
Slc41a1
solute carrier family 41, member 1
chr7_+_28440927 0.253 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr16_+_91485295 0.250 ENSMUST00000129878.1
Ifnar1
interferon (alpha and beta) receptor 1
chr10_+_94198955 0.249 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr19_+_11770415 0.247 ENSMUST00000167199.1
Mrpl16
mitochondrial ribosomal protein L16
chr3_-_105960099 0.244 ENSMUST00000118209.1
Atp5f1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1
chr12_+_44328882 0.244 ENSMUST00000020939.8
ENSMUST00000110748.2
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr17_-_27820534 0.243 ENSMUST00000075076.4
ENSMUST00000114863.2
D17Wsu92e

DNA segment, Chr 17, Wayne State University 92, expressed

chr16_-_31275277 0.243 ENSMUST00000060188.7
Ppp1r2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr1_+_163994866 0.237 ENSMUST00000111490.1
ENSMUST00000045694.7
Mettl18

methyltransferase like 18

chr11_+_79660532 0.237 ENSMUST00000155381.1
Rab11fip4
RAB11 family interacting protein 4 (class II)
chr17_-_74294834 0.236 ENSMUST00000078459.6
Memo1
mediator of cell motility 1
chr7_+_3290553 0.234 ENSMUST00000096744.5
Myadm
myeloid-associated differentiation marker
chr12_-_113260217 0.228 ENSMUST00000178282.1
Igha
immunoglobulin heavy constant alpha
chr2_+_32450444 0.224 ENSMUST00000048431.2
Naif1
nuclear apoptosis inducing factor 1
chr2_+_155381808 0.223 ENSMUST00000043237.7
ENSMUST00000174685.1
Trp53inp2

transformation related protein 53 inducible nuclear protein 2

chr2_-_119477613 0.223 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr12_+_84451485 0.222 ENSMUST00000137170.1
Lin52
lin-52 homolog (C. elegans)
chr16_+_31663841 0.217 ENSMUST00000115201.1
Dlg1
discs, large homolog 1 (Drosophila)
chr3_+_108284089 0.211 ENSMUST00000102632.4
Sort1
sortilin 1
chr6_+_86628174 0.211 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr3_+_32736990 0.210 ENSMUST00000127477.1
ENSMUST00000121778.1
ENSMUST00000154257.1
Ndufb5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5


chr5_-_134747241 0.206 ENSMUST00000015138.9
Eln
elastin
chr2_+_173659834 0.204 ENSMUST00000109110.3
Rab22a
RAB22A, member RAS oncogene family
chr7_+_126976338 0.202 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr2_-_73911323 0.201 ENSMUST00000111996.1
ENSMUST00000018914.2
Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr15_+_76343504 0.199 ENSMUST00000023210.6
Cyc1
cytochrome c-1
chr1_-_12991109 0.197 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr3_+_86224665 0.195 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr4_-_58912678 0.193 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
AI314180


expressed sequence AI314180


chr15_+_99702278 0.191 ENSMUST00000023759.4
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr8_-_91801547 0.190 ENSMUST00000093312.4
Irx3
Iroquois related homeobox 3 (Drosophila)
chr14_+_79481164 0.188 ENSMUST00000040131.5
Elf1
E74-like factor 1
chr6_-_128437653 0.188 ENSMUST00000151796.1
Fkbp4
FK506 binding protein 4
chr12_-_111712946 0.182 ENSMUST00000160825.1
ENSMUST00000162953.1
Bag5

BCL2-associated athanogene 5

chr5_-_72868431 0.179 ENSMUST00000073843.6
ENSMUST00000071944.6
ENSMUST00000113594.1
Tec


tec protein tyrosine kinase


chr2_+_26389334 0.179 ENSMUST00000076431.6
ENSMUST00000114093.1
Pmpca

peptidase (mitochondrial processing) alpha

chr12_-_111713185 0.176 ENSMUST00000054636.6
Bag5
BCL2-associated athanogene 5
chr17_-_46487641 0.168 ENSMUST00000047034.8
Ttbk1
tau tubulin kinase 1
chr3_+_122729158 0.165 ENSMUST00000066728.5
Pde5a
phosphodiesterase 5A, cGMP-specific
chr8_-_54529951 0.155 ENSMUST00000067476.8
Spcs3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr11_-_29547820 0.154 ENSMUST00000102844.3
Rps27a
ribosomal protein S27A
chr10_-_7681118 0.153 ENSMUST00000159977.1
ENSMUST00000162682.1
Pcmt1

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

chr12_+_82170016 0.152 ENSMUST00000166429.1
Sipa1l1
signal-induced proliferation-associated 1 like 1
chr7_-_86775860 0.149 ENSMUST00000001824.5
Folh1
folate hydrolase 1
chr4_+_54947976 0.147 ENSMUST00000098070.3
Zfp462
zinc finger protein 462
chr17_+_34644764 0.146 ENSMUST00000036720.8
Fkbpl
FK506 binding protein-like
chr2_-_76647992 0.144 ENSMUST00000002808.6
Prkra
protein kinase, interferon inducible double stranded RNA dependent activator
chr16_+_91485233 0.143 ENSMUST00000023689.4
ENSMUST00000117748.1
Ifnar1

interferon (alpha and beta) receptor 1

chr4_+_62663620 0.140 ENSMUST00000126338.1
Rgs3
regulator of G-protein signaling 3
chr4_-_156255327 0.128 ENSMUST00000179919.1
Samd11
sterile alpha motif domain containing 11
chr2_-_80129458 0.126 ENSMUST00000102653.1
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr14_-_101640434 0.121 ENSMUST00000168587.1
Commd6
COMM domain containing 6
chr4_-_140665891 0.118 ENSMUST00000069623.5
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr4_-_126202757 0.112 ENSMUST00000080919.5
Thrap3
thyroid hormone receptor associated protein 3
chr7_-_73537621 0.105 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr4_-_145194999 0.102 ENSMUST00000036579.7
Vps13d
vacuolar protein sorting 13 D (yeast)
chr17_-_27820445 0.101 ENSMUST00000114859.1
D17Wsu92e
DNA segment, Chr 17, Wayne State University 92, expressed
chr1_+_156035705 0.100 ENSMUST00000111754.2
ENSMUST00000133152.1
Tor1aip2

torsin A interacting protein 2

chr12_-_111712909 0.099 ENSMUST00000160576.1
Bag5
BCL2-associated athanogene 5
chr4_+_127243784 0.095 ENSMUST00000142029.1
Smim12
small integral membrane protein 12
chr5_+_119834663 0.095 ENSMUST00000018407.6
Tbx5
T-box 5
chr16_+_10545390 0.094 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a


C-type lectin domain family 16, member A


chr4_-_62360524 0.094 ENSMUST00000107461.1
ENSMUST00000084528.3
Fkbp15

FK506 binding protein 15

chr16_-_76403673 0.094 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chr8_+_3676299 0.086 ENSMUST00000044857.3
Trappc5
trafficking protein particle complex 5
chr5_-_24445166 0.078 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr11_+_54100924 0.077 ENSMUST00000093107.5
ENSMUST00000019050.5
ENSMUST00000174616.1
ENSMUST00000129499.1
ENSMUST00000126840.1
P4ha2




procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide




chr9_+_57521232 0.075 ENSMUST00000000090.6
Cox5a
cytochrome c oxidase subunit Va
chr11_+_4986824 0.075 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr3_+_38886940 0.072 ENSMUST00000061260.7
Fat4
FAT tumor suppressor homolog 4 (Drosophila)
chr3_-_94786430 0.069 ENSMUST00000107272.1
Cgn
cingulin
chr8_+_72443874 0.068 ENSMUST00000064853.6
ENSMUST00000121902.1
1700030K09Rik

RIKEN cDNA 1700030K09 gene

chr11_+_101070012 0.067 ENSMUST00000001802.9
Naglu
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
chr14_-_101640670 0.060 ENSMUST00000100339.2
Commd6
COMM domain containing 6
chr11_+_82115180 0.060 ENSMUST00000009329.2
Ccl8
chemokine (C-C motif) ligand 8
chr7_+_19083842 0.058 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
Dmpk



dystrophia myotonica-protein kinase



chr9_+_121950988 0.056 ENSMUST00000043011.7
Fam198a
family with sequence similarity 198, member A
chr6_-_11907419 0.053 ENSMUST00000031637.5
Ndufa4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
chr15_-_35938009 0.051 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr17_+_28177339 0.051 ENSMUST00000073534.2
ENSMUST00000002318.1
Zfp523

zinc finger protein 523

chr3_+_114030532 0.046 ENSMUST00000123619.1
ENSMUST00000092155.5
Col11a1

collagen, type XI, alpha 1

chr6_+_29396576 0.046 ENSMUST00000115275.1
Ccdc136
coiled-coil domain containing 136
chr16_-_65562686 0.046 ENSMUST00000004965.6
Chmp2b
charged multivesicular body protein 2B
chr9_+_44240668 0.043 ENSMUST00000092426.3
Ccdc153
coiled-coil domain containing 153
chr12_+_111713255 0.042 ENSMUST00000040519.5
ENSMUST00000160366.1
ENSMUST00000163220.2
ENSMUST00000162316.1
Apopt1



apoptogenic, mitochondrial 1



chr15_-_100551959 0.038 ENSMUST00000009877.6
Tfcp2
transcription factor CP2
chr11_-_33513736 0.038 ENSMUST00000102815.3
Ranbp17
RAN binding protein 17
chr5_-_24445254 0.037 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr4_+_131873608 0.037 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr3_-_94786469 0.036 ENSMUST00000107273.1
Cgn
cingulin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0043654 skeletal muscle satellite cell activation(GO:0014719) recognition of apoptotic cell(GO:0043654)
0.3 1.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.3 0.9 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.3 0.8 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.3 1.8 GO:0007296 vitellogenesis(GO:0007296)
0.3 0.8 GO:0097402 neuroblast migration(GO:0097402)
0.2 1.4 GO:0006570 tyrosine metabolic process(GO:0006570)
0.2 2.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.8 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.2 1.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 0.7 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.2 0.5 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.2 0.5 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 1.3 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.6 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.1 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.9 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.4 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.5 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.5 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.8 GO:0007144 female meiosis I(GO:0007144)
0.1 0.7 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.9 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.5 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.7 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.1 0.5 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.1 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 0.2 GO:0060282 positive regulation of chronic inflammatory response(GO:0002678) positive regulation of oocyte development(GO:0060282)
0.1 0.6 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.2 GO:0097494 regulation of vesicle size(GO:0097494)
0.1 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 1.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.3 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0033762 response to glucagon(GO:0033762)
0.0 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 1.3 GO:0046677 endochondral ossification(GO:0001958) replacement ossification(GO:0036075) response to antibiotic(GO:0046677)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0003211 cardiac ventricle formation(GO:0003211)
0.0 0.2 GO:0051004 plasma membrane to endosome transport(GO:0048227) regulation of lipoprotein lipase activity(GO:0051004)
0.0 1.6 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.0 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.4 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.3 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.0 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.0 GO:0035989 tendon development(GO:0035989)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.0 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
0.0 0.7 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 2.2 GO:0006457 protein folding(GO:0006457)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.2 0.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.0 GO:0042587 glycogen granule(GO:0042587)
0.1 2.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.2 GO:0071953 elastic fiber(GO:0071953)
0.1 0.3 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 1.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.6 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.3 2.2 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.7 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.1 1.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.4 GO:0034618 arginine binding(GO:0034618)
0.1 1.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 0.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 2.6 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.8 GO:0043495 protein anchor(GO:0043495)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 2.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.9 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.5 PID_ATM_PATHWAY ATM pathway
0.0 0.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.0 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.5 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.7 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.8 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.9 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.0 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 1.2 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.5 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.4 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1