Motif ID: Thrb

Z-value: 0.265


Transcription factors associated with Thrb:

Gene SymbolEntrez IDGene Name
Thrb ENSMUSG00000021779.10 Thrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Thrbmm10_v2_chr14_+_17660956_176609630.077.9e-01Click!


Activity profile for motif Thrb.

activity profile for motif Thrb


Sorted Z-values histogram for motif Thrb

Sorted Z-values for motif Thrb



Network of associatons between targets according to the STRING database.



First level regulatory network of Thrb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_112620030 0.321 ENSMUST00000180015.1
ENSMUST00000021726.6
 Adssl1

adenylosuccinate synthetase like 1

chr1_-_137969213 0.308 ENSMUST00000182680.1
ENSMUST00000182424.1
 Gm26936

predicted gene, 26936

chr3_+_67374091 0.254 ENSMUST00000077916.5
 Mlf1
myeloid leukemia factor 1
chr3_+_67374116 0.213 ENSMUST00000061322.8
 Mlf1
myeloid leukemia factor 1
chr5_-_92278155 0.204 ENSMUST00000159345.1
ENSMUST00000113102.3
 Naaa

N-acylethanolamine acid amidase

chr5_-_111761697 0.171 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr5_+_108065742 0.157 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
 Mtf2


metal response element binding transcription factor 2


chr11_+_49203465 0.156 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
 Zfp62


zinc finger protein 62


chr15_-_103251465 0.153 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
 Nfe2




nuclear factor, erythroid derived 2




chr3_-_36475688 0.127 ENSMUST00000029266.8
 Anxa5
annexin A5
chr11_+_109485606 0.127 ENSMUST00000106697.1
 Arsg
arylsulfatase G
chr9_+_102626278 0.127 ENSMUST00000038673.7
 Anapc13
anaphase promoting complex subunit 13
chr2_-_25469742 0.121 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr9_+_95857597 0.116 ENSMUST00000034980.7
 Atr
ataxia telangiectasia and Rad3 related
chr13_-_92530813 0.114 ENSMUST00000022217.8
 Zfyve16
zinc finger, FYVE domain containing 16
chr3_+_14863495 0.114 ENSMUST00000029076.4
 Car3
carbonic anhydrase 3
chrX_-_78583782 0.108 ENSMUST00000177904.1
 Prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chrX_-_78583882 0.107 ENSMUST00000114025.1
ENSMUST00000134602.1
ENSMUST00000114024.2
 Prrg1


proline rich Gla (G-carboxyglutamic acid) 1


chr2_-_25470031 0.105 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr15_-_100669496 0.097 ENSMUST00000182814.1
ENSMUST00000182068.1
 Bin2

bridging integrator 2

chr2_+_152962485 0.090 ENSMUST00000099197.2
ENSMUST00000103155.3
 Ttll9

tubulin tyrosine ligase-like family, member 9

chr3_-_79842662 0.081 ENSMUST00000029568.1
 Tmem144
transmembrane protein 144
chr16_+_36934976 0.079 ENSMUST00000023531.8
 Hcls1
hematopoietic cell specific Lyn substrate 1
chr9_-_102626095 0.072 ENSMUST00000093791.3
 Cep63
centrosomal protein 63
chr11_-_115612491 0.069 ENSMUST00000106507.2
 Mif4gd
MIF4G domain containing
chr5_+_108065696 0.060 ENSMUST00000172045.1
 Mtf2
metal response element binding transcription factor 2
chrX_+_112311334 0.058 ENSMUST00000026599.3
ENSMUST00000113415.1
 Apool

apolipoprotein O-like

chr4_+_152178126 0.055 ENSMUST00000075363.3
 Acot7
acyl-CoA thioesterase 7
chr16_+_32419696 0.054 ENSMUST00000014220.8
ENSMUST00000080316.7
 Tctex1d2

Tctex1 domain containing 2

chr2_+_92382911 0.053 ENSMUST00000054316.2
ENSMUST00000111280.2
 1700029I15Rik

RIKEN cDNA 1700029I15 gene

chr2_-_105399286 0.050 ENSMUST00000006128.6
 Rcn1
reticulocalbin 1
chr9_-_107668967 0.048 ENSMUST00000177567.1
 Slc38a3
solute carrier family 38, member 3
chr12_+_108334341 0.047 ENSMUST00000021684.4
 Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr9_-_102626509 0.046 ENSMUST00000161645.1
ENSMUST00000162297.1
ENSMUST00000162655.1
 Cep63


centrosomal protein 63


chr17_+_56162477 0.038 ENSMUST00000077788.6
 Tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr1_+_87214286 0.033 ENSMUST00000113231.3
 Eif4e2
eukaryotic translation initiation factor 4E member 2
chr4_+_20042046 0.026 ENSMUST00000098242.3
 Ggh
gamma-glutamyl hydrolase
chr14_+_54476100 0.025 ENSMUST00000164766.1
ENSMUST00000164697.1
 Rem2

rad and gem related GTP binding protein 2

chr2_+_32363192 0.021 ENSMUST00000048964.7
ENSMUST00000113332.1
 Ciz1

CDKN1A interacting zinc finger protein 1

chr11_-_103344651 0.016 ENSMUST00000041385.7
 Arhgap27
Rho GTPase activating protein 27
chr1_-_83408190 0.007 ENSMUST00000160953.1
 Sphkap
SPHK1 interactor, AKAP domain containing

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.2 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0097546 ciliary base(GO:0097546)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.0 0.0 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint