Motif ID: Ubp1

Z-value: 0.601


Transcription factors associated with Ubp1:

Gene SymbolEntrez IDGene Name
Ubp1 ENSMUSG00000009741.8 Ubp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ubp1mm10_v2_chr9_+_113930934_113930987-0.233.6e-01Click!


Activity profile for motif Ubp1.

activity profile for motif Ubp1


Sorted Z-values histogram for motif Ubp1

Sorted Z-values for motif Ubp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ubp1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 0.992 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr5_+_90772435 0.917 ENSMUST00000031320.6
 Pf4
platelet factor 4
chr10_-_128549125 0.897 ENSMUST00000177163.1
ENSMUST00000176683.1
ENSMUST00000176010.1
 Rpl41


ribosomal protein L41


chr2_-_151973387 0.887 ENSMUST00000109863.1
 Fam110a
family with sequence similarity 110, member A
chrX_-_134161928 0.881 ENSMUST00000033611.4
 Xkrx
X Kell blood group precursor related X linked
chr12_-_10900296 0.736 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr13_+_53525703 0.698 ENSMUST00000081132.4
 Gm5449
predicted pseudogene 5449
chr10_-_128549102 0.693 ENSMUST00000176906.1
 Rpl41
ribosomal protein L41
chrX_+_73483602 0.672 ENSMUST00000033741.8
ENSMUST00000169489.1
 Bgn

biglycan

chr7_-_44375006 0.669 ENSMUST00000107933.1
 1700008O03Rik
RIKEN cDNA 1700008O03 gene
chr17_+_29090969 0.667 ENSMUST00000119901.1
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr16_+_92498122 0.662 ENSMUST00000023670.3
 Clic6
chloride intracellular channel 6
chr10_+_14523062 0.653 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chrX_+_73639414 0.596 ENSMUST00000019701.8
 Dusp9
dual specificity phosphatase 9
chr7_-_4752972 0.585 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
 Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr10_+_31313375 0.565 ENSMUST00000000304.6
 Hddc2
HD domain containing 2
chr1_+_12718496 0.560 ENSMUST00000088585.3
 Sulf1
sulfatase 1
chr6_+_47244359 0.555 ENSMUST00000060839.6
 Cntnap2
contactin associated protein-like 2
chr18_+_35536539 0.555 ENSMUST00000081864.3
 Gm5239
predicted pseudogene 5239
chr7_-_127218303 0.552 ENSMUST00000106313.1
 Sept1
septin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 183 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.3 1.0 GO:0030421 defecation(GO:0030421)
0.3 1.0 GO:0051311 spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311)
0.2 1.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.9 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918)
0.2 0.8 GO:0030091 protein repair(GO:0030091)
0.1 0.8 GO:0032439 endosome localization(GO:0032439)
0.1 0.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.2 0.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.3 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.0 GO:0072687 meiotic spindle(GO:0072687)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.1 0.9 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 0.8 GO:0045179 apical cortex(GO:0045179)
0.2 0.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.7 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0022627 small ribosomal subunit(GO:0015935) cytosolic small ribosomal subunit(GO:0022627)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.2 0.6 GO:0033193 Lsd1/2 complex(GO:0033193)
0.1 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.6 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.8 GO:0008083 growth factor activity(GO:0008083)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.1 1.0 GO:0016805 dipeptidase activity(GO:0016805)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.2 0.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.7 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.6 GO:0042806 fucose binding(GO:0042806)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)

Gene overrepresentation in C2:CP category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 0.7 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.3 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 0.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.3 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.3 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.2 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID_CONE_PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.2 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 2.2 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 1.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 0.9 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.6 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.4 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)