Motif ID: Vdr

Z-value: 0.997


Transcription factors associated with Vdr:

Gene SymbolEntrez IDGene Name
Vdr ENSMUSG00000022479.9 Vdr



Activity profile for motif Vdr.

activity profile for motif Vdr


Sorted Z-values histogram for motif Vdr

Sorted Z-values for motif Vdr



Network of associatons between targets according to the STRING database.



First level regulatory network of Vdr

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_16752203 3.589 ENSMUST00000102884.3
ENSMUST00000020329.6
 Egfr

epidermal growth factor receptor

chr10_+_127725392 3.378 ENSMUST00000026466.3
 Tac2
tachykinin 2
chr10_+_79716588 2.308 ENSMUST00000099513.1
ENSMUST00000020581.2
 Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr5_+_17574268 2.137 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_-_19310035 1.723 ENSMUST00000003640.2
 Fosb
FBJ osteosarcoma oncogene B
chr3_-_88000350 1.693 ENSMUST00000090971.5
 Bcan
brevican
chr7_+_130865835 1.510 ENSMUST00000075181.4
ENSMUST00000048180.5
 Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr1_-_162859684 1.450 ENSMUST00000131058.1
 Fmo1
flavin containing monooxygenase 1
chr6_+_4903298 1.344 ENSMUST00000035813.2
 Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr4_+_123183722 1.294 ENSMUST00000152194.1
 Hpcal4
hippocalcin-like 4
chr4_+_148160613 1.243 ENSMUST00000047951.8
 Fbxo2
F-box protein 2
chr1_+_170308802 1.234 ENSMUST00000056991.5
 1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr6_+_4902913 1.193 ENSMUST00000175889.1
ENSMUST00000168998.2
 Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr11_-_118093702 1.185 ENSMUST00000018719.3
 Dnah17
dynein, axonemal, heavy chain 17
chrX_+_136741821 1.179 ENSMUST00000089350.4
 BC065397
cDNA sequence BC065397
chr1_-_180483410 1.174 ENSMUST00000136521.1
ENSMUST00000179826.1
 6330403A02Rik

RIKEN cDNA 6330403A02 gene

chr4_+_13743424 1.159 ENSMUST00000006761.3
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_129121699 1.121 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
 Hpca


hippocalcin


chr3_+_117575268 1.097 ENSMUST00000039564.6
 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr18_+_36281069 1.090 ENSMUST00000051301.3
 Pura
purine rich element binding protein A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 74 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 3.6 GO:0070459 prolactin secretion(GO:0070459)
0.8 3.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.8 2.5 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 2.5 GO:0070995 NADPH oxidation(GO:0070995)
0.5 2.3 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.4 2.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 1.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 1.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 1.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 1.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.4 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 1.1 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.1 1.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 1.0 GO:1902022 L-lysine transport(GO:1902022)
0.0 1.0 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.3 0.9 GO:0016056 photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 3.6 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.5 2.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.8 2.3 GO:0098855 HCN channel complex(GO:0098855)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.1 1.2 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.1 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 0.7 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.0 0.7 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.5 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 3.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.6 2.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 2.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.1 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 1.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.4 1.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 1.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 0.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)

Gene overrepresentation in C2:CP category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 3.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.8 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 1.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.6 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.1 1.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 0.9 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.8 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.6 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.4 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.6 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 2.3 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 2.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.7 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.6 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 1.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.4 REACTOME_IL_3_5_AND_GM_CSF_SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.1 0.3 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.1 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane