Motif ID: Zbtb18
Z-value: 0.793
Transcription factors associated with Zbtb18:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Zbtb18 | ENSMUSG00000063659.6 | Zbtb18 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zbtb18 | mm10_v2_chr1_+_177445660_177445821 | -0.30 | 2.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 88 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.9 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.3 | 1.7 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.0 | 1.5 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.4 | 1.3 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
| 0.1 | 0.9 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.1 | 0.9 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.0 | 0.8 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.0 | 0.7 | GO:1902993 | positive regulation of amyloid precursor protein catabolic process(GO:1902993) |
| 0.2 | 0.6 | GO:0099548 | trans-synaptic signaling by nitric oxide(GO:0099548) |
| 0.0 | 0.6 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
| 0.1 | 0.5 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
| 0.1 | 0.5 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.1 | 0.4 | GO:0061056 | positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) sclerotome development(GO:0061056) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 0.1 | 0.4 | GO:0002317 | plasma cell differentiation(GO:0002317) positive regulation of viral entry into host cell(GO:0046598) |
| 0.1 | 0.4 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.4 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.0 | 0.4 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 0.4 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.1 | 0.3 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
| 0.1 | 0.3 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 37 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.9 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 1.3 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.2 | 0.9 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 0.8 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.6 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.6 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.4 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 0.3 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.0 | 0.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 0.2 | GO:0097574 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) |
| 0.0 | 0.2 | GO:0031983 | vesicle lumen(GO:0031983) |
| 0.0 | 0.2 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.0 | 0.2 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.0 | 0.2 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 0.2 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
| 0.0 | 0.2 | GO:0001740 | Barr body(GO:0001740) |
| 0.0 | 0.2 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.2 | GO:0098533 | ATPase dependent transmembrane transport complex(GO:0098533) |
| 0.0 | 0.2 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 0.2 | GO:0016272 | prefoldin complex(GO:0016272) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 60 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 1.7 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.1 | 1.5 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 1.3 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 0.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.7 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.6 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.1 | 0.5 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.1 | 0.4 | GO:0005113 | patched binding(GO:0005113) |
| 0.1 | 0.4 | GO:0005534 | galactose binding(GO:0005534) |
| 0.0 | 0.4 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.0 | 0.4 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.3 | GO:0051378 | serotonin binding(GO:0051378) |
| 0.0 | 0.3 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.0 | 0.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 0.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.2 | 0.2 | GO:0005119 | smoothened binding(GO:0005119) |
| 0.1 | 0.2 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
| 0.1 | 0.2 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
Gene overrepresentation in C2:CP category:
Showing 1 to 9 of 9 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.7 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.6 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.6 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.5 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 0.5 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.4 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.0 | 0.3 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.2 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 23 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 1.8 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.7 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 1.4 | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 1.0 | REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.0 | 0.8 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.6 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 0.5 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 0.5 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.5 | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
| 0.0 | 0.4 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.4 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.0 | 0.4 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.0 | 0.4 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.3 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.2 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 0.2 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 0.2 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.2 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.0 | 0.1 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
