Motif ID: Zbtb3

Z-value: 0.575


Transcription factors associated with Zbtb3:

Gene SymbolEntrez IDGene Name
Zbtb3 ENSMUSG00000071661.6 Zbtb3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb3mm10_v2_chr19_+_8802486_88025300.672.5e-03Click!


Activity profile for motif Zbtb3.

activity profile for motif Zbtb3


Sorted Z-values histogram for motif Zbtb3

Sorted Z-values for motif Zbtb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb3

PNG image of the network

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Top targets:


Showing 1 to 20 of 119 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_20589471 1.167 ENSMUST00000100074.3
ENSMUST00000096197.4
 Vwa5b2

von Willebrand factor A domain containing 5B2

chr8_+_10272572 1.026 ENSMUST00000042103.8
 Myo16
myosin XVI
chr15_-_67113909 0.992 ENSMUST00000092640.5
 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr19_-_4334001 0.722 ENSMUST00000176653.1
 Kdm2a
lysine (K)-specific demethylase 2A
chr16_+_11405648 0.660 ENSMUST00000096273.2
 Snx29
sorting nexin 29
chr15_-_72546279 0.600 ENSMUST00000044624.6
 Kcnk9
potassium channel, subfamily K, member 9
chr17_+_24549950 0.590 ENSMUST00000035565.3
 Pkd1
polycystic kidney disease 1 homolog
chr19_-_59076069 0.578 ENSMUST00000047511.7
ENSMUST00000163821.1
 4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr7_-_63212514 0.575 ENSMUST00000032738.5
 Chrna7
cholinergic receptor, nicotinic, alpha polypeptide 7
chr5_+_115908644 0.553 ENSMUST00000141101.1
 Cit
citron
chr4_-_129662442 0.546 ENSMUST00000003828.4
 Kpna6
karyopherin (importin) alpha 6
chr6_-_28421680 0.510 ENSMUST00000090511.3
 Gcc1
golgi coiled coil 1
chr8_-_70439557 0.509 ENSMUST00000076615.5
 Crtc1
CREB regulated transcription coactivator 1
chr13_-_96132568 0.508 ENSMUST00000161263.1
 Sv2c
synaptic vesicle glycoprotein 2c
chr15_-_66969616 0.483 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr4_-_44167988 0.468 ENSMUST00000143337.1
 Rnf38
ring finger protein 38
chr9_-_40531362 0.467 ENSMUST00000119373.1
 Gramd1b
GRAM domain containing 1B
chr9_+_44499126 0.447 ENSMUST00000074989.5
 Bcl9l
B cell CLL/lymphoma 9-like
chr5_+_141856692 0.420 ENSMUST00000074546.6
 Sdk1
sidekick homolog 1 (chicken)
chr5_+_76840597 0.370 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
 C530008M17Rik


RIKEN cDNA C530008M17 gene



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.8 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.7 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.2 0.6 GO:0060854 patterning of lymph vessels(GO:0060854)
0.2 0.6 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.1 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 0.5 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.5 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.3 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.1 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.3 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0016459 myosin complex(GO:0016459)
0.1 0.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.1 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.5 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.2 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 0.6 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.6 REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport